Thiosalicylic acid hot sale

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Thiosalicylic acid in hot sale with competitive price

Thiosalicylic acid is an organosulfur compound containing carboxyl and sulfhydryl functional groups. Its molecular formula is C₆H₄(SH)(CO₂H). it is a yellow solid that is slightly soluble in water, ethanol and diethyl ether, and alkanes, but more soluble in DMSO.

Preparation and uses

Thiosalicylic acid is prepared from 2-aminobenzoic acid via diazotization.

Thiosalicylic acid is a precursor to the dyestuff thioindigo. Thiosalicylic acid is also used to make the vaccine preservative thiomersal.

Other aspects

It is a precursor to drug candidates for treatment of atherosclerosis and melanoma.

Product Name: Thiosalicylic acid

Synonyms: 2-Carboxythiophenol; 2-mercapto-benzoic acid; 
2-Sulfanylbenzoic acid; 2-thio-salicylicaci; 
Benzoic acid, o-mercapto-; o-Benzoic acid thiol;
o-benzoicacidthiol; o-Carboxythiophenol

CAS: 147-93-3     EINECS: 205-704-3

MF: C7H6O2S    MW: 154.19

Thiosalicylic acid Chemical Properties

Melting point  162-165 °C(lit.)

Boiling point  247.55°C (rough estimate)

density  1.49

refractive index  1.5100 (estimate)

Fp  150 °C

Storage temp.  0-6°C

Form  Fine Crystalline Powder

Color  White to yellow

Water Solubility  soluble in hot water

Sensitive  Air & Light Sensitive

CAS DataBase Reference 147-93-3(CAS DataBase Reference)

Safety Information

Hazard Codes   Xi,Xn,N

Risk Statements   36/37/38-20/21/22

Safety Statements   26-36/37/39-36

TSCA   Yes

HS Code   29309070

Hazardous Substances Data 147-93-3(Hazardous Substances Data)

Thiosalicylic acid Usage And Synthesis

Chemical Properties white to light yellow crystal powder

Uses
1. Trapping agent used in the desulfenylation of 3-indolyl sulfides.1 Condenses with diamines to form macrocyclic diamides.2

2. Used as trapping agent in the desulfenylation of 3-indolyl sulfides;Used to condense with diamines to form macrocyclic diamides.

3. A trapping agent used in the desulfenylation of 3-indolyl sulfides

Definition: A sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid.

Purification Methods
Crystallise the thio acid from hot EtOH (4mL/g), after adding hot distilled water (8mL/g) and boiling with charcoal. The hot solution is filtered, cooled, the solid is collected and dried in vacuo (P2O5). Crystallise it from AcOH and sublime in vacuo.