Tetrabutylammonium bromide 99%,1-Butanaminium,N,N,N-tributyl-,bromide

Details:

Tetrabutylammonium bromide Basic information

Tetrabutylammonium bromide, a quaternary ammonium compound widely used as a phase transfer catalyst. TBAB decreases the retention time and removes peak tailing by acting as an ion pair reagent during the chromatographic analysis of quaternary ammonium compounds. In the molten state, TBAB behaves like an ionic liquid, which is a promising green alternative to organic solvents in polymer synthesis.

Physical and Chemical Properties Application Uses preparation Toxicity

Product Name:		Tetrabutylammonium bromide
Synonyms:		1-Butanaminium, N,N,N-tributyl-, bromide;1-Butanaminium,N,N,N-tributyl-,bromide;n,n,n-tributyl-1-butanaminiubromide;ALIQUAT(R) 100;IPC-TBA-BR;Tetrabutylazanium bromide;Tetrabutylaminium·bromide;Tetrabutylammonium bromide, 99%, for ion-pair chromatography
CAS:		1643-19-2
MF:		C16H36BrN
MW:		322.37
EINECS:		216-699-2
Product Categories:		organo amine halide;Other Products;Ammonium Salts Essential Chemicals;Reagent Plus;Routine Reagents; Ammonium SaltsAnalytical Reagents;Electrochemistry; Supporting Electrolytes for Electrochemistry;AnionicHPLC; Chromatography/CE Reagents;Ion Pair;Ion Pair Reagents; Ion Pair Reagents - Anionic;Ion Pair Reagents - Anionic Concentrate; quarternary ammonium salts;Ammonium Bromides (Quaternary); Analytical Chemistry;HPLC Ion-Pair Reagents for Acidic Samples; Ion-Pair Reagents for HPLC;Quaternary Ammonium Compounds; Ammonium, Phosphonium, Sulfonium Salts (Ionic Liquids); Ionic Liquids;Synthetic Organic Chemistry;Ammonium Salts; Greener Alternatives: Catalysis;Phase Transfer Catalysts; Pharmaceutical intermediates;1643-19-2
	Tetrabutylammonium bromide Chemical Properties

Melting point	102-106 °C(lit.)
Boiling point	102 °C
Density	1.039 g/mL at 25 °C
Refractive index	n20/D 1.422
Fp	100℃
storage temp.	Store below +30°C.
solubility	H2O: 0.1 g/mL, clear, colorless
Form	Crystalline Powder
Color	White to slightly cream
Specific Gravity	1.007
Odor	Amine like
Water Solubility	600 g/L (20 ºC)
λmax	λ: 240 nm Amax: 0.04 λ: 250 nm Amax: 0.03 λ: 260 nm Amax: 0.02 λ: 500 nm Amax: 0.02
Sensitive	Hygroscopic
Stability:	Stable. Incompatible with strong oxidizing agents. Protect from moisture.
CAS Data	1643-19-2
NIST Chemistry Reference	Tetra-N-butylammonium bromide(1643-19-2)
Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-22
Safety Statements	26-36-37/39
WGK Germany	3
F	3
Hazard Note	Irritant
TSCA	Yes
HS Code	29239000
Chemical Properties	white crystals or powder
Uses	PTC catalyst

Tetrabutylammonium bromide Application:

Used as a reagent for the analysis of organic synthesis.
2. an effective phase transfer catalyst.
3. For organic synthesis intermediates, phase transfer catalyst
4. Ion-pairing reagents for the synthesis of bacampicillin, sultamicillin like.
5. Ion pair chromatography reagents, phase transfer catalyst. Bacampicillin, sultamicillin like synthesis.

 

Tetrabutylammonium bromide (TBAB) is a quaternary ammonium compound. It is the most widely used phase transfer catalyst. Its interfacial properties have been studied in case of hydroxide initiated reactions. This may be applied in understanding the mechanism of phase transfer reactions. TBAB is reported to decrease retention time and remove peak tailing by acting as an ion pair reagent during the chromatographic analysis of quaternary ammonium compounds. In the molten state TBAB behaves like an ionic liquid which is a promising green alternative to organic solvents in organic synthesis. Its molar heat capacity, entropy and free energy function have been determined.
Recently, molten tetrabutylammonium bromide (TBAB) was used as a low toxic and cost-effective IL in a number of constructive synthetic transformations.
Tetrabutylammonium bromide (TBAB) may be used in the molten state in the following processes:
Synthesis of (2S)-5-(3-phenyl-2-phthalimidylpropanoylamino)isophthalic acid.
Synthesis of alkyl-substituted pyrroles in the absence of catalyst and organic solvent.
Synthesis of dithioacetals from acetals by transthioacetalisation in a solvent free environment.
Synthesis of polyamides (PAs) by the polymerization of terephthalic acid and diisocyanates.
Catalyze the addition of thiols to conjugated alkenes.
Dehydrochlorination of poly(vinyl chloride).

Tetrabutylammonium bromide, a quaternary ammonium compound widely used as a phase transfer catalyst. TBAB decreases the retention time and removes peak tailing by acting as an ion pair reagent during the chromatographic analysis of quaternary ammonium compounds. In the molten state, TBAB behaves like an ionic liquid, which is a promising green alternative to organic solvents in polymer synthesis.

Tetrabutylammonium Bromide is used in the synthesis of polymer solar cells. Also used in the synthesis of single component green-light emitting electrochemical cells.

Tetrabutylammonium bromide may be used as a catalyst in the synthesis of following:

1-cyano-2-thiophenylethane

1-cyano-2-thiobutylethane

1-cyano-2-(2-aminothiophenyl)ethane

methyl 3-thiophenylpropionate

methyl 3-thiobutylpropionate

methyl 2-methyl-3-thiophenylpropionate

methyl 2-methyl-3-thiobutylpropionate

diethyl 2-thiophenylsuccinate

diethyl 2-thiobutylsuccinate

3-(4-chlorophenyl)-2-nitro-2-thiophenylpropane

4-(4-chlorophenyl)-3-nitro-4-thiobutylbutane

3-thiophenylcyclohexanone

3-thioethylcyclohexanone

4-methyl-4-thiophenylpentan-2-one

4-methyl-4-thiobutylpentan-2-one

4-thiophenylbutan-2-one

4-thiobutylbutan-2-one

3-thiophenylbutanal

3-thiobutylbutanal