Resatorvid (TAK-242)

Resatorvid (TAK-242)

Resatorvid (TAK-242)

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50 Milligram

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  • Min.Order :50 Milligram
  • Purity: 98%
  • Payment Terms : T/T,

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Resatorvid TAK-242 Resatorvid (TAK-242)

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Resatorvid (TAK-242) is a potent TLR4 signaling inhibitor which selectively inhibits the TLR4-mediated production of cytokines and nitric oxide.

Details:

Product Name: Resatorvid (TAK-242)  

Synonyms: TAK-242; CLI-095

CAS No.:243984-11-4


Synonyms: (6R)-6-[[(2-Chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid ethyl ester


Molecular Formula: C15H17ClFNO4S


Molecular Weight: 361.82


Appearance: Light yellow solid


Purity: >98%; ee,>98% by HPLC


Solubility: DMSO


Storage: at -20°C 2 years; Store in a tightly closed container, in a cool and dry place.

Biological Activity of TAK-242
TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock.TAK-242 (resatorvid), a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, inhibits the production of lipopolysaccharide-induced inflammatory mediators by binding to the intracellular domain of TLR4. 

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