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1 Kilogram |
Negotiable |
2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose Tetra-O-benzyl-D-glucopyranose 4132-28-9
Superiority
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Quality Standard:
Item |
Specification |
Appearance |
White to offwhite powder or crystalline solid |
Assay (HPLC), % |
≥98 |
Melt point, ℃ |
147-154 |
Specific Rotation [α]20/D, ° |
15.5-22(C=1,CHCl3) |
Loss on dry, % |
≤1.0 |
Residue on ignition,% |
≤0.10 |
TLC |
Single spot |
Properties: It is a white to offwhite powder or crystalline solid. Insoluble in water£¬slightly soluble in dioxane and soluble in toluene etc.
Uses:This product is an important pharmaceutical intermediates and be used in synthesis voglibose, miglitol, dapagliflozin, and such as valienamine moiety of acarbose, bicyclic spiroacetal unsaturated glucoside of avermectin subunit, methoxy substituted THF synthons of annonaceous aeetogenins, serotype O-antigen oligosaccharides of shigella flexneri, phthalocyanine-glycoconjugates for photodynamic therapy, sugar-drug conjugate for molecular targeted therapies and so on. It also be used to synthesize some bioactive substance, for example, nojirimycin, aminocyclopentitol and tetrahydroimidazopyridines with glycosidase inhibitory activity, aspalathin with plasma glucose-lowering properties, rebeccamycin and glucosylisophosphoramide mustard with anti-tumor activity diosgenin analogue with anticancer activity to cervicouterine, ferrocen-tetrabenzyl glucose conjugate with antimalarial activity, bicyclic carbohydrates possessed activity against Leishmania donovani, glucopyranosyl phosphocholine with antifungal active, flavone glycoside with antioxidant and neuroprotective activities, aza-inositol with protein kinase B inhibitory activity, glucogallin with aldose reductase inhibitory activity, and glucosyl-2-azetidinone with cholesterol absorption inhibitory activity. This product is also used in synthesis arbutin, carminic acid, methoxyphenyl di-D-glucopyranoside as cryoprotectant, 1-O-octyl-D-glucitol as ice recrystallization inhibitor, alkyl glucoside surfactant, amphiphilicity block polymer in ink composition, metallofullerene glycoconjugates and the like. In addition, this product is also used as synthon of 2,3,4,6-tetra-O-benzyl-D-glucono-1,5-lactone, trehalose, disaccharides, glycopeptides, pseudo-fructose, trehazolamine, septanoside, C-glycoside, various glycosylation donors such as 2,3,4,6-tetra-O-benzyl-D-glucopyranosyl trichloroacetimidate, 1-deoxy-1-halo / thio / thiophenyl / isopropyl / trimethylsilane-tetrabenzyl glucose, 1-O-acyl / alkynyl / allyl-tetrabenzyl glucose, etc..
Storage: Maintain in cool, dry containment.
Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in China. Through more than four years development, our company has developed from single product at first to providing solution to finished products now, is committed to providing solutions for success and growth through long term relationships.
Currently, our products have been exported to more than 50 countries all over the world. Our service is accomplished by providing good quality solution that matches the specifications of our clients at competitive price. Our products will derive from trusted sources and arrive to our clients in time and well arranged manner, be creating the greatest benefits for our customers.
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