Ruxolitinib API & Intermediates

Min.Order / FOB Price:Get Latest Price

1 Gram	Negotiable

1 Gram

Negotiable

Min.Order :1 Gram
Purity: ≥99%
Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

Ruxolitinib INCB-018424 941678-49-5

Quick Details

Appearance:
Application:Ruxolitinib is a Janus kinase inhibitor that is used in the treatment of intermediate or high risk myelofibrosis. Ruxolitinib is associated with transient and usually mild elevations in serum aminotra
PackAge:Barrel sealed
ProductionCapacity:1000|Kilogram|Day
Storage:
Transportation:

Superiority:

Our company has commercialized this product for long-term stable supply, the purity ≥ 99.5%. At present, our sales of this product have reached more than 480 kg.

Details:

Ruxolitinib is an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.

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