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Caffeic acid good supplier manufacturer 331-39-5 Hot sale 331-39-5
Caffeic acid has antidiabetic, antioxidant, anticarcinogenic, and anti-inflammatory activities, it can suppress ultraviolet B(UVB)-induced COX-2 expression by blocking Fyn kinase activity, inhibits HBV-DNA replication as well as HBsAg production, also reduces serum DHBV level in DHBV-infected duckling model. Caffeic acid may be used as designed novel therapeutic drugs for Parkinson's disease by inhibiting α-synuclein fibrillation.
Caffeic acid can shrink and strengthen microvessels, reduce permeability, improve coagulation function and the number of leukocytes and platelets. Clinically, it is commonly used in the prevention and treatment of various surgical and medical bleeding. It has a significant effect on gynecological bleeding diseases. It is also used for leukopenia caused by chemotherapy, radiotherapy and other reasons, It also has a certain effect on diseases such as primary thrombocytopenia and aplastic leucopenia.
Extraction Method: Single spike cimicifuga rhizome is extracted with methanol which is removed through concentration under reduced pressure. Add hot water to the residue to dissolve it. Heating the water to dissolve the residue, and further filter the insolubles upon heating. After cooling, add benzene for extraction with the benzene solution being washed with 1% aqueous sodium bicarbonate and further collecting the washed solution. Add dilute hydrochloric acid for acidification, and then apply benzene to remove the free organic acid; Concentrate under reduced pressure to get rid of the benzene with the residue being the enriched product of caffeic acid.
Formal Name
3-(3,4-dihydroxy
CAS Number
331-39-5
Synonyms
Molecular Formula
C9H8O4
Formula Weight
180.2
Purity
≥97%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
SMILES
OC1=C(O)C=C(/C=C/C(O)=O)C=C1
CAS NO:331-39-5
CAS NO:331-39-5
CAS NO:331-39-5
CAS NO:331-39-5
CAS NO:331-39-5
CAS NO:331-39-5
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