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331-39-5 Caffeic acid supplier factory 331-39-5 Caffeic acid Top quality Caffeic acid
Caffeic acid belongs to common phenolic compounds with effects of increasing the levels of white blood cells. It is easily to be confused with caffeine and is widely distributed in the plant kingdom. Its major plant sources include lemon peel, Ranunculaceae cimicifuga rhizome, and valerian root. Caffeic acid, together with ferulic acid, erucic acid, and p-hydroxy cinnamic acid are ubiquitous hydroxy cinnamic acid-class molecule distributed in various kinds of plants. This kind of products has conjugated double bonds in the side chain of the molecular structure, and thus exhibiting significant fluorescence upon ultraviolet light, mostly showing bluish color fluorescence. This is a advantage for paper chromatography tests or thin layer chromatography tests.
Detoxifing effect of green coffee has been used for a long time. CAFA is an innovative form of the native caffeic acid, which has been specifically created for cosmetics applications. Being highly water soluble, stable and purified, it brings five synergistic actions to prevent UV inducing photo-ageing.
Application: caffeic acid is safe to be applied in cosmetics and has a broader antibacterial and antiviral activity. It can also absorb ultraviolet radiation. A low concentration of it already has inhibitory efficacy on the generation of skin melanin. Its applied amount in the beauty products for whitening is at the range of 0.5 to 2%. It can also be used as additive for the oxidized hair dyes which is good for enhancing the strength of the color.
Preparation: it can be produced from the Perkin’s reaction between protocatechuic aldehyde and acetic acid,As follows:
Caffeic acid, NF-kappaB inhibitor
Specific NF-κB inhibitor
Specific NF-κB inhibitor (IC50 = 8.8 μM). Antioxidant, immunomodulatory and anti-inflammatory effects in vitro and in vivo. Additionally inhibits HDAC (IC50 = 0.85 mM). Blood-brain barrier permeable.
> 98%
331-39-5
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