Tofacitinib Citrate...

Tofacitinib Citrate exporter suppliers 540737-29-9 in bulk supply

Tofacitinib Citrate exporter suppliers 540737-29-9 in bulk supply

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0 Metric Ton

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  • Min.Order :0 Metric Ton
  • Purity: ≥99%

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Tofacitinib Citrate exporter suppliers 540737-29-9 540737-29-9 in bulk supply

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  • Appearance:White crystal
  • Application:Pharmaceutical excipient
  • PackAge:1kg/bag, 5kg/drum, 25kg/drum
  • ProductionCapacity:|Metric Ton|Day
  • Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
  • Transportation:By air/by sea/by courier

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Tofacitinib Citrate exporter suppliers 540737-29-9 in bulk supply

Tofacitinib citrate, chemically called 3-(3R, 4R)-4-methyl-3-(7H-tuck and 2,3-d) On November 6, 2012, the U.S. Food and Drug Administration (FDA) and Pfizer jointly announced that Tofatinib is approved for use in adult patients with moderate to severe active rheumatoid arthritis (RA) who are inadequate or intolerant of metformin treatment, and Tofacitinib is the pioneering drug developed for rheumatoid arthritis treatment, known as Xeljanz.

Tofatinib can effectively choose to inhibit JAK3, and at the same time, JAK1, JAK2 also has inhibitory effect, thus blocking a series of jaKs-mediated cytokine signaling pathways in the system of abnormal cytokine level, inhibiting the transmission of abnormal immune signals, effectively controlling the RA course, the inhibition effect of other tyrosine kinase is weak, can reduce the range of adverse reactions

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