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SF 2312(SF2312) 107729-45-3 107729-45-3
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SF 2312 is a highly potent, low-nanomolar inhibitor of Enolase with IC50 of 37.9 nM and 42.5 nM for recombinant hENO1 and hENO2 respectively; has selectively toxic, blocks glycolysis in ENO1-deleted glioma cells, and is previously isolated as natural phosphonate antibiotic of unknown mode of action.
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SF 2312 is a highly potent, low-nanomolar inhibitor of Enolase with IC50 of 37.9 nM and 42.5 nM for recombinant hENO1 and hENO2 respectively; has selectively toxic, blocks glycolysis in ENO1-deleted glioma cells, and is previously isolated as natural phosphonate antibiotic of unknown mode of action.
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