What is the role of sodium citrate as a biochemical reagent?

Details:

As a chemical substance, sodium citrate is widely used in the field of food, which has caused panic among many people, worried that it is harmful to the body. In fact, it is not the case. The raw materials for making this substance come from food, and there is no harm in the human body ingesting an appropriate amount of sodium citrate every day. It can be a non-toxic additive, and everyone can rest assured.

Sodium citrate not only has a prominent role in the food industry, but also has extraordinary effects in medicine. Sodium citrate acts as a diuretic and anticoagulant. Everyone knows that sodium citrate is made from lemon, and sodium citrate itself contains a lot of citric acid. After it is effectively combined with the calcium ions of the human body, it can become a soluble substance, which can prevent excessive blood flow. coagulation effect.
The application of sodium citrate in food must be familiar to everyone, and what is the role of sodium citrate as a biochemical reagent
The role of sodium citrate:
Sodium citrate is a very important citrate now. It is mainly produced by fermentation of starch substances to produce citric acid, which is then neutralized with alkali substances. Lemon juice contains a large amount of citric acid, and the combination of citric acid and calcium ions becomes soluble. The complex can relieve the effect of calcium ions to promote blood coagulation, and can prevent and treat hypertension and myocardial infarction. So it can play an anticoagulant effect. When taking fresh blood clinically, it is necessary to add some sterilized sodium citrate or sodium oxalate to prevent blood coagulation, so sodium citrate and sodium oxalate are called blood anticoagulants.
In the biological industry, sodium citrate is also one of the commonly used buffers. Sodium citrate buffer 0.01mol/L, pH6.0 is a commonly used antigen retrieval solution, which can be used for paraffin sections, frozen sections and other samples. Antigen retrieval after fixation with formaldehyde, formaldehyde or other aldehyde reagents. It can effectively remove the cross-linking between proteins caused by aldehyde fixative reagents and fully expose the antigenic epitopes in samples such as paraffin sections, thereby greatly improving the immunostaining effect.
Through the above understanding, the application of sodium citrate in medicine also has a good effect, and the source of sodium citrate is also relatively easy. Therefore, there are many manufacturers of sodium citrate in the current market, but not many are refined. Our company is a manufacturer specializing in the production and development of blood Collection tube additives (blood anticoagulants, blood coagulants). The company has been established for decades. In addition to the production of sodium citrate, Hubei New Desheng Materials Co., Ltd. also produces many products. If you are interested in our products, you can enter our official website to contact customer service consultation. Hubei Xindesheng welcomes you.