72-19-5 L-Threonine

Superiority:

Legal number: CAS RN: 72-9-5; 6028-28-0; EINECS no. : 200-774-1

　　Molecular formula: C₄H₉NO₃

　　Molecular weight: 119.12

　　Physical and chemical properties: white orthorhombic system or crystalline powder. Odourless, taste sweet. 256 ℃ melting and decomposition. Soluble in water, 25 ℃ solubility is 20.5 g / 100 ml.

　　Purpose: THR is a kind of important nutrition fortifier, can be fortified cereals, pastries, dairy products, and tryptophan has to restore the body fatigue, promote the effect of the growth and development. Medicine, because of the structure containing hydroxyl threonine, effect on human skin with moisture, combined with oligosaccharide chain, play an important role in protecting cell membrane, can promote the synthesis of phosphate ester and fatty acid oxidation in the body.

　　Standard: USP24

 

Threonine was discovered in fibrin hydrolysates by W.C.R. in 1935 and proved to be the last essential amino acid to be discovered. Its chemical name is. α-amino-β-hydroxybutyric acid. The molecular formula is NH2-CH(C00H)-CHOH-CH3, which has four stereoisomerism, and only the L-form has biological activity.

 

 

Chinese name: L-threonine

 

 

 

English name :L-Threonine

 

Alias name: L-hydroxybutyline (2S,3R) -2-amino-3-hydroxybutyric acid L-α-amino-β-hydroxybutyric acid L-Isozygote amino acid

 

More nicknames :(2S,3R)-2-Amino-3-hydroxybutyric acid a-Amino-β-hydroxybutyric acid

 

Molecular formula: C4H9NO3

 

Molecular weight: 119.12

 

 

use

1. Mainly used as a nutritional supplement. It is easy to produce burnt incense and chocolate fragrance when co-heated with glucose, and has the effect of increasing fragrance. It can also be used in biochemical research.

 

2. Threonine is an essential amino acid for feed fortifier. Threonine, which is often added to the diets of young piglets and poultry, is the second limiting amino acid in pig diets and the third limiting amino acid in poultry diets. It is added to the feed of wheat, barley and other cereals.

 

3. Nutritional additives, also used to prepare amino acid infusion and synthetic amino acid preparations.

 

4. It is used as an adjuvant treatment for digestive ulcers. Can also treat anemia and angina pectoris, aortitis, heart insufficiency and other cardiovascular system diseases.

 

5. Threonine (L-threonine) was isolated and identified from fibrinolysis products by W.C. Rudd in 1935, and has been proved to be the last essential amino acid discovered. It is the second or third restrictive amino acid of livestock and poultry, and it plays an extremely important physiological role in animals. Such as promoting growth, improving immune function, etc.; Balance the amino acids of the diet to make the proportion of amino acids closer to the ideal protein, so as to reduce the requirement of protein content in the feed of livestock and poultry. Lack of threonine can lead to reduced feed intake, growth arrest, decreased feed utilization, immunosuppression and other symptoms. In recent years, lysine and methionine compound products have been widely used in feed, and threonine gradually becomes a limiting factor affecting animal performance. Further research on threonine is helpful to effectively guide livestock and poultry production.

 

Threonine (L-threonine) is an amino acid that can not be synthesized by animals themselves, but is very needed. It can be used to accurately balance the amino acid composition of feed, meet the needs of animal growth and maintenance, improve weight gain and lean meat rate, and reduce the feed to meat ratio. It can improve the nutritional value of feed materials with low amino acid digestibility and improve the performance of low energy feed. It can reduce the crude protein level of feed, improve the nitrogen utilization rate of feed and reduce the feed cost. It can be used for pig, chicken, duck and advanced aquatic products. L-threonine is a feed additive produced by deep liquid fermentation and refining with corn starch and other raw materials using bioengineering principle. It can adjust the balance of amino acids in feed, promote growth, improve meat quality, improve the nutritional value of feed raw materials with low amino acid digestibility, produce low protein feed, help to save protein resources, reduce the cost of feed raw materials, reduce the nitrogen content in livestock manure and urine, ammonia concentration and release speed in livestock and poultry houses. It is widely used to add piglet feed, breeding pig feed, broiler feed, prawn feed and eel feed.

 

6. Threonine (L - threonine) in the body of catabolism, was the only through deamination and transamination, but directly through the threonine dehydratase, threonine dehydrogenase and threonine aldolase catalytic into other substances, amino acids such as threonine can shift ChengDing acyl coenzyme A, succinyl coa, serine, glycine, etc. In addition, excessive threonine can increase the activity of lysine-α-ketogluconate reductase. Adding appropriate threonine to the diet can eliminate the decrease of body weight gain caused by excessive lysine, and the decrease of protein/deoxyribonucleic acid (DNA) and ribonucleic acid (RNA)/DNA ratio in liver and muscle tissue. Addition of threonine also alleviated growth inhibition caused by excess tryptophan or methionine. It HAS BEEN REPORTED THAT MOST OF THE ABSORPTION OF THREONINE IN CHICKENS OCCURS IN THE DUODENUM, CHEST, AND STOMACH, WHEN THE THREONINE IS ABSORBED, IT IS RAPIDLY CONVERTED INTO LIVER PROTEINS, WHICH ARE DEPOSITED IN THE BODY.