Factory high quality Cetrorelix acetate 120287-85-6

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1 Gram	FOB Price:USD 1.0000 -5.0000

1 Gram

FOB Price:USD 1.0000 -5.0000

Min.Order :1 Gram
Purity: purity 98%-101%
Payment Terms : L/C,T/T,Other

Keywords

Cetrorelix acetate 120287-85-6 CETRORELIX ACID

Quick Details

Appearance:white powder
Application:Dietary supplements;Food;Additives;Pharmaceuticals;medicines;cosmetics Heart protection
PackAge:1kg/bag,5kg/bag,25kg/drum
ProductionCapacity:1|Metric Ton|Day
Storage:20°
Transportation:20

Superiority:

Cetrorelix

CAS: 120287-85-6

Molecular Formula: C70H92ClN17O14

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120287-85-6

120287-85-6 - Names and Identifiers

Name	Cetrorelix
Synonyms	CETRORELIX Cetrorelix Cetrorelixum CETRORELIX ACID Cetrorelix [INN] Cetrorelix acetate CETRIZINEDIHYDROCHLORIDE Cetrorelixum [inn-latin] AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2 N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(pyridin-3-yl)-D-alanyl-L-seryl-L-tyrosyl-N~5~-carbamoyl-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide D-alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N~5~-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl- (2S)-N-[(2R)-1-Amino-1-oxopropan-2-yl]-1-[(2S,5S,8R,11S,14S,17R,20R,23R)-2-(3-carbamimidamidopropyl)-8-[3-(carbamoylamino)propyl]-20-(4-chlorobenzyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-23-(2-naphthylmethyl)-4,7,10,13,16,19,22,25-octaoxo-17-(pyridin-3-ylmethyl)-3,6,9,12,15,18,21,24-octaazahexacosan-1-oyl]pyrrolidine-2-carboxamide (non-preferred name)
CAS	120287-85-6
EINECS	686-384-6
InChI	InChI=1/C70H92ClN17O14/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102)/t40-,50-,51+,52+,53-,54-,55+,56-,57-,58 /m1/s1

120287-85-6 - Physico-chemical Properties

Molecular Formula	C70H92ClN17O14
Molar Mass	1431.04
Density	1.42±0.1 g/cm3(Predicted)
Melting Point	>259°C (dec.)
Solubility	DMSO (Slightly, Heated), Methanol (Very Slightly)
Appearance	White powder
Color	White to Off-White
pKa	9.82±0.15(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.667

120287-85-6 - Reference Information

overview	cetrorelix acetate is a synthetic decapeptide, which is mainly used in assisted reproductive technology to prevent early ovulation for patients with controlled ovarian stimulation. cetrorelix acetate is also often called cetrorelix, which is a gonadotropin-releasing hormone (GnRH) antagonist, it can compete with endogenous LHRH to bind receptors on the pituitary cell membrane, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary in a dose-dependent manner.
pharmacological effects	cetrorelix acetate is a gonadotropin-releasing hormone (GnRH) antagonist. This product competes with endogenous GnRH for receptors on pituitary cells, thereby inhibiting the release of endogenous luteinizing hormone (LH) and follicle stimulating hormone (FSH), delaying the appearance of LH peaks, thereby controlling ovulation. The effect of this product is dose-dependent, the inhibitory effect is direct, and it is maintained by continuous treatment, and it does not cause the luteinizing hormone receptor activity to rise at the beginning and then down-regulated.
application	cetrorelix acetate is a synthetic decapeptide, which is mainly used in assisted reproductive technology to prevent premature ovulation for patients with controlled ovarian stimulation. cetrorelix acetate is also often called cetrorelix, which is a gonadotropin-releasing hormone (GnRH) antagonist, it can compete with endogenous LHRH to bind receptors on the pituitary cell membrane, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary in a dose-dependent manner.
detection method	step 1, weigh cetrorrik acetate, dissolve with acetonitrile, dilute with acetonitrile and sulfate buffer solution to prepare impurity reference substance solution; Step 2, weigh cetrorrik acetate, add acetonitrile to dissolve, and dilute with acetonitrile and sulfate buffer solution, prepare a solution containing cetrorelix; step 3, take the impurity reference solution and the test solution respectively and inject it into the liquid chromatograph, record the chromatogram, and calculate the content of each impurity by the peak area according to the external standard method; this method Effectively solve the problem of separating the related substances of its preparation. This method has strong specificity and good repeatability, and can ensure the controllability of the related substances in its preparation.
effect	cetrorelix acetate (cetrorelixAcetate), also commonly known as cetrorelix, is an effective progesterone releasing hormone inhibin (LH-RH) receptor antagonist, which can control ovarian stimulation, prevent premature discharge of immature follicles and help conception, so it is often used as a preparation for injection.

Details:

Cetrorelix acetate

Mol Download Chemical properties

CAS:

120287-85-6

MF:

C70H92ClN17O14

MW:

1431.04

EINECS:

686-384-6

MDL No.:

MFCD00884467

Properties

Melting point:

>259°C (dec.)

Density

1.42±0.1 g/cm3(Predicted)

storage temp.

Refrigerator

solubility

DMSO (Slightly, Heated), Methanol (Very Slightly)

form

Solid

pka

9.82±0.15(Predicted)

color

White to Off-White

InChIKey

SBNPWPIBESPSIF-MHWMIDJBSA-N

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