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Hydroxyecdysone 5289-74-7 Beta-Ecdysterone
Molecular Formula | C27H44O7 |
Molar Mass | 480.64 |
Density | 1.0760 (rough estimate) |
Melting Point | 242-244°C |
Boling Point | 498.63°C (rough estimate) |
Specific Rotation(α) | +61.8 (CHCl3) |
Flash Point | 392.3°C |
Solubility | Soluble in methanol, DMSO, insoluble in petroleum ether. |
Vapor Presure | 8.7E-23mmHg at 25°C |
Appearance | White needle crystal |
Color | white |
Merck | 13,3525 |
BRN | 1917578 |
pKa | 14.13±0.70(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Refractive Index | 1.5800 (estimate) |
MDL | MFCD00036740 |
Physical and Chemical Properties | White crystalline powder, soluble in ethanol, slightly soluble in acetone, slightly soluble in hot water, ethyl acetate, chloroform, almost insoluble in ether, derived from the leakage of Lu, Achyranthes bidentata, Pearl Dew grass Cyanotis,arachnoidea, brazilian ginseng (Pfaffia glomerata). |
Pharmacological effects: It can promote the synthesis of colloidal protein, anti-arrhythmia, and anti-fatigue; promote cell growth, stimulate dermal cell division, and eliminate cholesterol in the body; lower blood lipids, inhibit blood sugar rise; clear channels and activate collaterals, dehumidification and analgesia, etc. Physiological activity.
Last Update:2022-10-16 17:25:55
overview | ecdysone acts on the human body to promote protein synthesis, eliminate cholesterol in the body, lower blood lipids, inhibit blood sugar rise and other physiological activities, folk used for rheumatoid arthritis. In the sericulture industry, it is used to shorten the age of silkworm and promote silkworms; in the breeding industry, the breeding of prawns and crabs is also widely used; in cosmetics, ecdysone is also used as a special additive; Ecdysone is added to cosmetics to prevent dry skin and make skin more tender. Ecdysone can affect the entire development stage of insects from hatching larvae to adults, so it controls or kills agricultural pests. It has been developed and applied as the third generation pesticide; ecdysone also has certain effects on the physiological process of crops, and has good development and application prospects in crop yield additives. |
properties | light yellow crystalline powder, odorless, hygroscopic, and gradually darker after light. |
Ingredients | Ecdysone or ecdysteroid hormones and ecdysteroids are steroid hormones of arthropods that participate in the regulation of molting, development, and to a lesser extent affect reproduction. Ecdysone includes ecdysone, 20-hydroxyecdysone, 2-deoxyecdysone, etc. These compounds are usually converted from food-borne cholesterol and are catalyzed by enzymes of the Halloween gene family in cytochrome P450. Many plants often contain plant ecdysteroids, which act as toxins or antifeedants to combat herbivorous insects. |
application | ecdysone can promote gum protein synthesis, anti-arrhythmia and anti-fatigue on human body. Promote cell growth, stimulate dermal cell division, and eliminate cholesterol in the body; Lowering blood lipid and inhibiting blood sugar rise; It has physiological activities such as dredging meridians and activating collaterals, dehumidification and analgesia. It is a natural anti-cancer preparation. Since its inception in 1976, ecdystic hormone of deusis, indefinite tablets, injections and ointments have been developed. Folk is used for rheumatoid arthritis. It has a good effect in the treatment of rheumatism and arthritis patients with different symptoms. Its effective ingredient 20-hydroxyecdysterone has been proved by clinical studies to have a direct hypoglycemic effect, and the total effective rate for type 2 diabetes is 84%. It is particularly obvious to improve the symptoms of "three more and one less" in diabetic patients. |
use | ecdysone is used to shorten the age of silkworm, neatly clustered, and promote silking and cocoon formation. Hormones; High-grade cosmetics; Health care products. β-ecdysone has the effects of promoting gum protein synthesis, anti-arrhythmia and anti-fatigue. it plays a key role in insect growth, development, cell expansion and apoptosis, and regulates molting and metamorphosis by regulating gene expression. |
CAS:
5289-74-7
MF:
C27H44O7
MW:
480.64
EINECS:
811-097-1
MDL No.:
MFCD00036740
Melting point:
242-244 °C
Boiling point:
498.63°C (rough estimate)
Density
1.0760 (rough estimate)
refractive index
1.5800 (estimate)
storage temp.
Sealed in dry,Store in freezer, under -20°C
solubility
alcohol: soluble
pka
14.13±0.70(Predicted)
form
powder
color
white
Merck
13,3525
BRN
1917578
InChIKey
NKDFYOWSKOHCCO-YPVLXUMRSA-N
SMILES
O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C |&1:1,4,6,9,17,20,22,24,26,29,r|
LogP
-0.270 (est)
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