Factory high qualit...

Factory high quality Bimatoprost GMP
Factory high quality Bimatoprost GMP

Factory high quality Bimatoprost GMP

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price:USD 159.0000 -170.0000

  • Min.Order :1 Gram
  • Purity: purity 98%-101%
  • Payment Terms : L/C,T/T,Other

Keywords

Bimatoprost 155206-00-1 Bimatoprost

Quick Details

  • Appearance:white powder
  • Application:Dietary supplements;Food;Additives;Pharmaceuticals;medicines;cosmetics Heart protection
  • PackAge:1kg/bag,5kg/bag,25kg/drum
  • ProductionCapacity:1|Kilogram|Day
  • Storage:20℃
  • Transportation:low temp

Superiority:

155206-00-1 - Physico-chemical Properties

Molecular Formula C25H37NO4
Molar Mass 415.57
Density 1.145±0.06 g/cm3(Predicted)
Melting Point 66-68°C
Boling Point 629.8±55.0 °C(Predicted)
Flash Point 334.7°C
Solubility Soluble in ethanol (~50 mg/ml), methanol, DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (
Vapor Presure 9.94E-17mmHg at 25°C
Appearance Crystalline solid
Color White to Off-White
pKa 14.25±0.20(Predicted)
Storage Condition -20°C
Stability Light Sensitive
Refractive Index 1.591

155206-00-1 - Physico-chemical Properties

Molecular Formula C25H37NO4
Molar Mass 415.57
Density 1.145±0.06 g/cm3(Predicted)
Melting Point 66-68°C
Boling Point 629.8±55.0 °C(Predicted)
Flash Point 334.7°C
Solubility Soluble in ethanol (~50 mg/ml), methanol, DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (
Vapor Presure 9.94E-17mmHg at 25°C
Appearance Crystalline solid
Color White to Off-White
pKa 14.25±0.20(Predicted)
Storage Condition -20°C
Stability Light Sensitive
Refractive Index 1.591

 

 

 

155206-00-1 - Preparation Method

Open Data Verified Data

with (3aR,4R,5R,6as)-hexahydro-4-(3-oxygen -5-phenyl-1E-pentenyl) -5-(p-phenyl butyryloxy)-2H-cyclopento [B] furan -2-ketone as raw material. After reduction, the carbonyl group on the furan ring is reduced to a hydroxyl group, which is hydrolyzed and then condensed with triphenylphosphine of valeric acid to obtain 7-[(1R,2R,3R,5S)-3,5-= hydroxy 2 A [(3 S) a 5 phenyl -3-[(tetrahydro-2-H-pyran-2-yl) oxy]-1E-pentenyl] cyclopentyl]-52-heptenoic acid. Hydrolysis removes the protecting group on the hydroxyl group of the pentenyl side chain. Methyl Ester was obtained by dissolving methyl iodide in dimethylformamide under the action of Cs2 C03, and finally reacted with an aqueous solution of ethylamine to obtain the product.

 

155206-00-1 - Use

Open Data Verified Data

developed by Allergan, Inc., USA, was first launched in the United States in 2001. Prostaglandin F2 a stimulator. The product selectively mimics the action of prostacyclin produced in the body, lowering intraocular pressure by increasing aqueous humor flow in the scleral pathway of the microscleral network and the pigmented layer. It is used in patients with open-angle glaucoma, or in patients with elevated intraocular pressure who are ineffective with other intraocular pressure lowering drugs (cannot reach a predetermined level of intraocular pressure after multiple measurements) or cannot tolerate.

Details:

Bimatoprost

CAS:

155206-00-1

MF:

C25H37NO4

MW:

415.57

EINECS:

642-890-9

MDL No.:

MFCD03411999

Properties

Melting point:

66-68°C

Boiling point:

629.8±55.0 °C(Predicted)

Density 

1.145±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)

pka

14.25±0.20(Predicted)

form 

solid

color 

White to Off-White

BCS Class

3

Stability:

Light Sensitive

InChIKey

AQOKCDNYWBIDND-FTOWTWDKSA-N

SMILES

C(NCC)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCC1=CC=CC=C1

Xi'an Eastling biotech Co., Ltd. is dedicated to the research and development, production, and sales of natural plant extracts; With nearly 15 years of experience in identifying, researching, developing, and producing active ingredients for medicinal plants, we focus on providing innovative products and services to customers in industries such as pharmaceuticals, health food, and cosmetics.

 

Eastling Biotechnology has established a global direct harvesting system for plant raw materials, ensuring the high quality and authenticity of raw materials, while also protecting the continuity and diversity of plants; Having strong research and development capabilities, we can develop more effective and specialized plant active ingredients for the pharmaceutical, health food, and cosmetics industries; We have established an advanced quality control system, and the quality control of our products depends on advanced testing instruments and high-level technical experts. The effective combination of the two forms Eastling's ability to quickly and rigorously control product quality.

 

We have a production system that complies with Chinese GMP and American cGMP certifications, as well as advanced and optimized large-scale industrial production technology. In addition to producing specific products for Eastling Biotechnology, we also provide customized services to meet the characteristics and needs of different customers to produce customized products.

We believe that natural active ingredients are the foundation of our service to customers. Scientific and effective production technology is the foundation for us to provide customers with specialized products. We have the ability to serve customers in the pharmaceutical, health food, and cosmetics industries, provide new product solutions, and add new value to their products.

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