N,N'-Diisopropylcar...

N,N'-Diisopropylcarbodiimide 98% supplier in China

N,N'-Diisopropylcarbodiimide 98% supplier in China

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,T/T

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N,N'-Diisopropylcarbodiimide supplier N,N'-Diisopropylcarbodiimide China N,N'-Diisopropylcarbodiimide 98%

Quick Details

  • Appearance:Colorless to pale yellow liquid
  • Application:dehydrating agent
  • PackAge:180kg/drum
  • ProductionCapacity:|Metric Ton|Day
  • Storage:sealed storage in shady and cool warehouse
  • Transportation:negotiable

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Details:

1. Introduction of N,N'-Diisopropylcarbodiimide

N,N'-Diisopropylcarbodiimide, often abbreviated to DIC, DIPC or DIPCDI, is a coupling agent often used widely in organic chemistry for the synthesis of amides, peptides, esters and various heterocycles.


2. Basic Information of N,N'-Diisopropylcarbodiimide

N,N'-Diisopropylcarbodiimide is white or light yellow transparent liquid in normal temperature with boiling point: 145-148; it dissolves in benzene, alcohol, ethyl ether, but not in water.

 

1). Properties

Indes                                  High Grade                    Grade 1                Qualified                      
Appearane  transparent White transparent liquid White transparent Light yellow liquid
Content,% 99.0  98.5 98.0
Boiling point,℃ 145-148 145-148 145-148
Acetone Insoluble Matter None None None


2) use
In a similar fashion to the synthesis of amide bonds, N,N'-Diisopropylcarbodiimide can also be used to form esters from carboxylic acids via activated ester intermediate as follows:

DIC is widely used as a dehydrating agent in the synthesis of a diverse range of heterocycles. Recent examples (Scheme 4) include the formation of dihydroquinazolines on solid-phase using DIC and HOBt,12 synthesis of 2-oxazolines (6) from N-(b-hydroxyl)amides13 and trisubstituted imidazolidinones.

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