Add time:10/01/2019 Source:sciencedirect.com
The highly stereoselective trifluoropyruvate-ene reaction with steroidal 1,1-disubstituted Δ20(22)-side chain olefin was achieved by the dicationic BINAP-Pd complex as an effective chiral Lewis acid catalyst to give the Δ20(21)-steroidal ene-product in high yield and enantioselectivity. The ene product itself without (dehydro)lactone and lactam structures exhibited remarkably high antagonist activity for human osteocalcin even in low binding affinity for human vitamin D hormone receptor.
We also recommend Trading Suppliers and Manufacturers of Ethyl trifluoropyruvate (cas 13081-18-0). Pls Click Website Link as below: cas 13081-18-0 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View