2-Butoxyethanol increases hemangiosarcomas selectively in male mouse liver after chronic inhalation through mechanisms that have not fully been elucidated. Hemolysis, a primary toxic effect associated with 2-butoxyethanol exposure in rodents, increased hemosiderin (iron) deposition in Kupffer ce...

Ethylene glycol monobutyl ether (EGBE), also known as 2-butoxyethanol (2-BE), has been identified as a contaminant in hydraulic fracturing fluids. In order to determine the presence of 2-BE in hydraulic fracturing chemical additives, a reliable method for recovering 2-BE from aqueous phases by l...

2-Butoxyethanol and sorbitan monolaurate are major components of oil dispersants that are applied in large quantities to control oil spill in the aquatic environment. An important question is whether aquatic animals are equipped with mechanisms for the detoxification of these oil dispersant comp...

A method for the separation and quantitation of the enantiomers of 3-tert.-butylamino-1,2-propanediol by high-performance liquid chromatography and evaporative light scattering detection has been developed. Separation of the enantiomers was performed in normal-phase liquid chromatography on a Ch...

An efficient synthesis of 5-hydroxyalbuterol is described starting from 2,3-dihydroxybenzoic acid. The key step utilizes the Stille cross-coupling reaction to install the side-chain functionality.

A novel hypocrellin congener, 2-butylamino-2-demethoxy-hypocrellin B (2-BA-2-DMHB) was found to be an effective photosensitizer. Compared with its parent compound hypocrellin B (HB), its absorption bands extended toward longer wavelength and the extinction coefficients raised to some degree (λm...

The compounds of general formula [ML2](ClO4)2 [M = Cu(II), Ni(II), Co(II), Zn(II)]; L = diethyl [(n-butylamino-N)(pyridin-2-yl)]methylphosphonate (2-pmape) were prepared. The stoichiometry and stereochemistry of the complexes were confirmed by elemental analysis, infrared, electronic spectral, 1...

In this study, 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol, (BR-AEA), was designed, synthesized, characterized and tested in docking studies and in vitro. Previous to its synthesis, a set of compounds, including well-known ligands and boron co...

The present study reports the synthesis and characterization of 2,2'-(diazene-1,2-diylbis(4,1-phenylene))bis(6-(butylamino)-1H-benzo[de]isoquinoline-1,3(2 H)-dione) (4) using a dual approach consisting of experimental and computational techniques. The indigenously synthesized compound 4 is ...

Copper(I) bromide dissolves in deoxygenated methylene chloride and nitrobenzene solutions of equimolar N,N′- diethylethylenediamine (DEED) to give the colorless copper(I) dimer [(DEED)CuBr]2 (D). Dioxygen uptake, analytical, cryoscopic, spectral and kinetic data show that D is oxidized to the b...

o-Phthalaldehyde and N-(1-naphthyl)-N′-diethylethylenediamine give red or orange colours with urea and certain substituted ureas in dilute hydrochloric acid at 37°. The reaction has good sensitivity and the colours are fairly stable. An individual urea can be detected at a concentration of ca....

The results of heat capacity measurements at constant pressure, Cp, on the thermochromic compound bis(N,N-diethylethylenediamine)copper(II) tetrafluoroborate with an adiabatic calorimeter between 13 and 343 K are reported. An appreciable heat capacity effect was found at 302.64 K with a long hea...

N,N′-diethylethylenediamine-N,N′-diacetic acid and N′,N′-diethylethylenediamine-N,N-diacetic acid were prepared via a classical cyanomethylation process and subsequently isolated by displacement cation-exchange chromatography. N,N′-diethylethylenediamine-N,N′-diacetic acid melted with deco...

N,N-Bis(2-mercaptoethyl)-N′,N′-diethylenediamine (BMEDA) is used in the preparation of the 188Re-BMEDA-liposome as a chelator to deliver rhenium 188 into liposomes. Although the safety of the 188Re-BMEDA-liposome had been established, the use of BMEDA in preparing the liposome is of interest; ...

A novel linear flexible ONNO-type tetradentate ligand, N,N′-diethylethylenediamine-N,N′-di-α-butyrate (deedba), and the dichloro, diaqua and amino acid (glycine, l-alanine, l-phenylalanine) cobalt(III) complexes of deedba have been synthesized via an H2O2 oxidation method. During the preparat...

Mannich reaction of resorcin[4]arene with N,N′-diethylethylenediamine and formaldehyde produced a singly bridged resorcinarene-dimer bearing sixteen hydroxyl groups at their peripheral positions, which exists in a closed capsular conformation including the diazahexamethylene bridge chain betwee...

The continuous temperature-induced change of the ligand field strain in a pseudo-Jahn–Teller thermochromic crystal bis(N,N-diethylethylenediamine)copper(II) tetrafluoroborate was studied. In situ powder photodiffraction was employed to demonstrate that at the low-temperature limit of the gradua...

The aldol condensation of acetaldehyde and heptanal has been carried out in the liquid phase between 353 and 413 K using different types of solid base catalysts: MgO with strong Lewis basic sites, Mg(Al)O mixed oxides with acid–base pairs of the Lewis type obtained from hydrotalcite precursor, ...

Amorphous aluminophosphate (AlP) and metal-aluminophosphates (MAlPs, where M = 2.5 mol% Cu, Zn, Cr, Fe, Ce, or Zr) were prepared by coprecipitation method. Their surface properties and catalytic activity for the synthesis of jasminaldehyde through the aldol condensation of n-heptanal and benzald...

A fully automated in-tube solid phase microextraction/liquid chromatography-post column derivatization-mass spectrometry (in-tube SPME/LC-PCD-MS) method was developed for the analysis of urinary hexanal and heptanal. Online in-tube SPME enabled effective enrichment of the low level aldehydes and...