The applicability of 2-bromoethyl glycosides in carbohydrate synthesis is demonstrated by the synthesis of glycosides of α-l-Fuc-(1→2)-d-Gal and β-d-Gal(1→4)-d-GlcNAc. The bromoethyl aglycon was transformed into the methoxycarbonylethylthioethyl spacer, which allowed coupling of the sugars t...

The reaction of primary amines with N-(2-bromoethyl)glutarimide derivatives leads to N-(2-hydroxyethyl)iminoglutarimides in good yields. The possible mecanism is proposed.

An efficient synthesis of cyclohexane- and cyclopentane-1,3-dione-2-spirocyclopropanes from 1,3-cycloalkanediones using sulfonium salts was achieved. The reaction of 1,3-cycloalkanediones with (1-aryl-2-bromoethyl)-dimethylsulfonium bromides and powdered K2CO3 in EtOAc provided the corresponding...

The stable isomer of N-(2 bromoethyl) phthalimide (NBEP) is determined. FT-IR (4000–400 cm−1) and FT-Raman (3500–100 cm−1) spectra were recorded on the solid phase of the molecule. Optimized geometrical parameters, vibrational wavenumbers of the stable isomer of NBEP are predicted by DFT/B3LYP...

We have developed a facile and efficient synthetic route to substituted isochromans for the first time by reacting 2-(2-bromoethyl)benzaldehyde with a variety of aryl, heteroaryl amines in AcOH. The reaction is catalyst/additive free and takes place at reflux conditions with short reaction time ...

Treatment of 3-phenyl-1,3-thiazolidin-4-one derivative 1 with phenylisothiocyanate in DMF, in the presence of potassium hydroxide, at room temperature gave the non-isolable potassium salt 2. The in-situ reaction of 2 with differently substituted N-aryl hydrazonoyl chlorides 3, 7a–d and 14a–d a...

Bidimensional novel cadmium metal-organic frameworks (MOFs) based on the 1,3-bis(4-pyridyl)propane linker and flexible dicarboxylate ligands derived from glutarate (2-methylglutarate, 2-dimethylglutarate and 3-methylglutarate) have been synthesized by conventional routes. These MOFs show fascina...

Six new asymmetric derivatives of diazenes with a general formula of CnH2n + 1OC6H3(NNC6H4X)2 in which n are even parity numbers from 8 to 14 and X = Cl and Br have been synthesized and their molecular structures were characterized by physical measurements and spectroscopic methods (FT-IR, 1D an...

Bis-[3-methyl-1,1′,4′-triaryl-5-oxo-spiro-pyrazoline-4,5′-pyrazoline] derivatives are synthesized regio- and stereoselectively via 1,3-dipolar cycloaddition of the bis-hydrazonoyl chlorides with 4-arylidenepyrazol-5-one derivatives. The cycloaddition route is optimized under both ultrasonic i...

Concomitant cathodic reduction of 9,10-phenanthrenequinone and 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane (DDT), under constant potential conditions, led to new and interesting [1,3]dioxoles through two possible and simultaneous reaction pathways: (1) an electron-transfer from the quinone di...

Epoxies are widely used in many engineering applications, however, their fracture energy remains less than desired and conventional toughening agents usually lead to compromised tensile strength. In this study, a simple one-pot blending method was used, in which both graphene oxide and a block i...

Macromolecular dynamics of sulfonated poly(styrene-b-ethylene-ran-butylene-b-styrene) (sSEBS) triblock copolymers were investigated using broadband dielectric spectroscopy (BDS). Two main relaxations corresponding to the glass transitions in the EB and S block phases were identified and their te...

Nanocomposite films were prepared via syntheses of SrTiO3 nanoparticles in films of sulfonated poly(styrene-b-ethylene-co-butylene-b-styrene) (sSEBS) block copolymer templates. SrTiO3 ionic and alkoxide precursors permeated selectively into styrene domains in which formation and growth of crysta...

A series of partially sulfonated polystyrene-block-poly(ethylene-ran-butylene)-block-polystyrene copolymers (SSEBS) was synthesized and the sulfonation was characterized qualitatively by a Fourier transform-infra red (FT-IR) and quantitatively by an elementary analysis. The membranes from synthe...

1,3-Bis(4-methoxyphenyl)cyclohexane-1,3-diyl cation radical gives 1,5-bis(4-methoxyphenyl)bicyclo[3.1.0]hexane through 1,3-bis(4-methoxyphenyl)cyclohexane-1,3-diyl when generated by photoinduced electron transfer, but gives 4,4″-dimethoxy-m-terphenyl when generated by using one-electron oxidant...

The thiaminalisation of 2-amino-2-(mercaptomethyl)propane-1,3-diol [‘2-(hydroxymethyl)cysteinol’] with aryl(di)aldehydes is reported. The resulting new class of 2-aryl-4,4-bis(hydroxymethyl)-1,3-thiazolidines is investigated by NMR and IR spectroscopy in tandem with DFT calculations, permittin...

We present here a general and easy method for the synthesis of several 2-aryl-1,3-benzoselenazoles from the reaction of bis(2-aminophenyl) diselenides with different aryl aldehydes, promoted by the non-toxic inorganic reducing agent sodium metabisulfite (Na2S2O5) in DMSO at 120 °C. This efficie...

Our initial lead compound 2 was modified to improve its metabolic stability. The resulting compound 5 showed excellent metabolic stability in rat and human liver microsomes. We subsequently designed and synthesized a hybrid compound of 5 and the 1,3-bis(aryloxy) benzene derivative 1, which was p...

The structure of 3-(4-bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbaldehyde was determined by using X-ray diffraction analysis. Photophysical studies of the title compound were investigated in the solvents with different polarities. The emission spectrum of the compound was recorded in po...

The synthesis and characterization of a series dipalladium(I) complexes of formulae [Pd{1-[2′-(methoxycarbonyl)phenyl]-3-[4′-X-phenyl]triazenide}]2 [X = F (4), Cl (5), Br (6)] are reported. The crystal structure of complex 4 was determined by X-ray diffraction studies. The previously reported ...