A new approach for groundwater treatment combines a permeable Fe(0) barrier to break down higher chlorinated solvents like PCE and TCE with a downgradient aerobic biological treatment system to biotransform less chlorinated solvents, such as DCE and vinyl chloride (VC), and petroleum hydrocarbon...
Background Three experiments were conducted to examine the overall hypothesis that addition of medium chain triglycerides (MCT) and cysteamine hydrochloride (CSH) into the diets of young and growing pigs would stimulate the endogenous somatotropic axis to improve growth and performance. Result...
In this study, a selenoprotein W cDNA was cloned from topmouth culter (Erythroculter ilishaeformis), and it was designated as EISelW. The EISelW open reading frame was composed of 261 base pairs (bp), encoding 86-amino-acid protein. The 5′ untranslated region (UTR) consisted of 104 bp, and the ...
Cysteamine (Cys) is the only treatment of cystinosis in pediatric patients. Cys is available as the hydrochloride (Cys-HCl), the bitartrate (Cys-Bitar) salts and as phosphocysteamine (Cys-Phos). It has been suggested that Cys-Bitar and Cys-Phos are better tolerated and may have a better bioavai...
Background Intestinal absorption of hypoglycin A (HGA) and its metabolism are considered major prerequisites for atypical myopathy (AM). The increasing incidence and the high mortality rate of AM urgently necessitate new therapeutic and/or preventative approaches.Objectives To identify a substan...
Background Several pasture management strategies have been proposed to avoid hypoglycin A (HGA) intoxication in horses, but their efficacy has never been investigated.Objectives To evaluate the effect of mowing and herbicidal spraying on HGA content of sycamore seedlings and the presence of HGA ...
L-α-amino-methylenecyclopropyl propionic acid (Hypoglycin A, HGA) has been found to be the toxic compound in fruits of the Sapindaceae family causing acute intoxication when ingested as food or feed. Clinical symptoms are consistent with acquired multiple acyl-CoA dehydrogenase deficiency (MADD...
Because high‐quality seeds are essential for successful crop production in challenging environments, understanding the molecular bases of seed vigour will lead to advances in seed technology. Histone deacetylase inhibitors, promoting histone hyperacetylation, are used as tools to explore aspect...
Background and Purpose Short‐chain fatty acids are fermentation end products produced by gut bacteria, which have been shown to ameliorate inflammatory bowel diseases and allergic asthma. However, the mechanism involved remains largely unknown. Here, we investigate the protective effects and me...
Background and PurposeSodium butyrate (NaB), an epigenetic modifier, is effective in promoting insulin sensitivity. The specific genomic loci and mechanisms underlying epigenetically induced obesity and insulin resistance and the targets of NaB are not fully understood.Experimental ApproachThe a...
A series of copolymers were synthesized by chemically oxidative polymerization of p-phenylenediamine (PPD) and o-phenetidine (PHT) in acidic aqueous media. The polymerization yield, intrinsic viscosity, and solubility of the copolymers were comprehensively studied by changing the comonomer ratio...
Copolymerization of meta-phenylenediamine (mPD) and ortho-phenetidine (PHT) was performed by three facile electropolymerization techniques including cyclic voltammetry, constant potential and constant current on platinum electrodes in H 2 SO 4 . The electrochemically functional c...
Present study is focused on the development of conducting polymer based copolymer composite coating materials for corrosion protection of mild steel. Copolymer composites were synthesized by chemical oxidative copolymerization of an equimolar mixture of aniline and phenetidine. Coatings were dev...
4-Hydroxyphenylpyruvic acid dioxygenase (HPD; EC 1.13.11.27) is an important enzyme in tyrosine catabolism in most organisms. Decreased activity of 4-hydroxyphenylpyruvic acid dioxygenase in the liver of mouse strain III is associated with tyrosinemia. We report a nucleotide substitution that ge...
The enzyme 4-hydroxyphenylpyruvic acid dioxygenase (HPD) catalyzes the reaction of 4-hydroxyphenylpyruvic acid to homogentisic acid in the tyrosine catabolism pathway. A deficiency in the catalytic activity of HPD may lead to tyrosinemia type III, an autosomal recessive disorder characterized by...
Tocopherols, the lipid-soluble antioxidants known collectively as vitamin E, are produced by photosynthetic organisms, which play important roles not only in human and animals but plants as well. 4-hydroxyphenylpyruvic acid dioxygenase is the first committed enzyme of this biosynthesis pathway. ...
Kaempferol is a major flavonoid in the human diet and in medicinal plants. The compound exerts anxiolytic activity when administered orally in mice, while no behavioural changes were observed upon intraperitoneal administration, or upon oral administration in gut sterilized animals. 4-Hydroxyphe...
Several phenolic compounds derived from plant biomass are attracting attention because they display high antioxidant activity. In this study, antioxidant activity was confirmed in 4-hydroxyphenylacetic acid (HPA), and transesterification reaction using Candida antarctica lipase B was performed t...
Immobilization and hybridization of oligonucleotides or specific-gene PCR product (DENV-1), a conserved genomic sequence of the dengue virus, onto graphite electrode modified with poly(4-hydroxyphenylacetic acid), were carried out with success using both direct electrochemical oxidation of guani...
Defects in processing speed and memory are common in multiple sclerosis (MS) patients. In other populations, amphetamines have been shown to enhance cognition, but their use is limited by adverse behavioral effects. The l-isomer may have equivalent cognition enhancement with less adverse effects...
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