A new chelating resin, covalently linked 1,6-bis(2-carboxy aldehyde phenoxy)butane with the Amberlite XAD-16 was synthesized and used for preconcentration of Cu(II) and Cd(II) prior to their determination by flame atomic absorption spectrometry (FAAS). It was characterized by elemental analyses ...

Gallic acid was immobilized on Amberlite XAD-16 by coupling it through –NN group. The resulting chelating resin AmberliteXAD-16 gallic acid, characterized by thermogravimetric analysis (TGA), infrared (IR) spectra and BET analysis, was used to preconcentrate Cr(III), Mn(II),Fe(III),Co(II), Ni(I...

The sorption of U(VI) by N, N-dibutyl, N′-benzoylthiourea (DBBT) impregnated resin has been studied. DBBT impregnated resin was prepared by direct adsorption of chelating ligand onto macroporous support, Amberlite XAD-16. The adsorption of DBBT on the macroporous support is shown by FTIR spectr...

Amberlite XAD-16 has been functionalized with 2-acteyl pyridine by coupling it with 2-chloro pyridine after acetylation. The resulting resin (AP-XAD 16) has been characterized by various techniques like FT-IR, TGA, elemental analysis, etc. and has been evaluated for the solid phase extraction of...

The present study aims to investigate the adsorption behavior of Pb2 +, Cd2 +, Cu2 + and Ni2 + ions from aqueous solution onto modified Amberlite XAD-16 functionalized using 2, 2'– (Ethylenedithio) diethanol with chlorosulphonic acid. The batch equilibrium method was used for studying the ...

Ferulic acid (FA) is a valuable organic antioxidant, which is contained in various grains and fruits. FA is usually found in water streams of food industry. In order to find an alternative method for recovery of FA, this study was focused in adsorption of FA on XAD-16. The pH effect (2–8) and t...

A novel approach has been improved for the preconcentration of Th(IV) and Ce(III) by using thermophilic Anoxybacillus flavithermus which were immobilized on Amberlite XAD-16 resin and analyzed by Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). The concentration of Th(IV) and ...

The Amberlite XAD-16-pyridylazo resorcinol resin (AXAD-16-PAR) has been synthesized and characterized by both FT-IR spectra and scan electron microscope besides elemental chemical analysis. The optimization of U(VI) sorption conditions by the prepared resin is determined by the batch equilibrium...

A new chelating resin was synthesized for the selective removal of potentially toxic Pb (II) and Cu (II) by the functionalization of a ligand dipicolylamine on the Amberlite XAD-16 resin through azo (NN) linkage. Physicochemical parameters of the synthesized XAD-DP resin were characterized by us...

Mycobacterium tuberculosis and Mycobacterium avium infections cause the two most important mycobacterioses, leading to increased mortality in patients with AIDS. Various 5-substituted 2′-deoxyuridines, uridines, 2′-O-methyluridine, 2′-ribofluoro-2′-deoxyuridines, 3′-substituted-2′,3′-dide...

Osteopenia and sarcopenia develops rapidly during disuse. The study investigated whether intermittent parathyroid hormone (1–34) (PTH) and growth hormone (GH) administered alone or in combination could prevent or mitigate disuse osteopenia and sarcopenia in rats.Disuse was achieved by injecting...

BackgroundWhile the inverse relationship between serum ionized calcium (Ca2+) and PTH is well-established, the relationship between 25(OH)D and PTH showed conflicting results. The study aimed to evaluate the relative contributions of age, sex, serum Ca2+, ionized magnesium (Mg2+), 25(OH)D and 1,...

Osteoporosis is accompanied by insufficient osteogenic capacity. Several lines of evidence suggested that solutions to enhance osteoblastogenesis were important strategies for osteoporotic bone defect repair. This study investigated the effect of combined treatment with vitamin K2 and PTH on bon...

Parathyroid hormone (PTH) has been a major contributor to the anabolic therapy for osteoporosis, but its delivery to bone without losing activity and avoiding adverse local effects remain a challenge. Being the natural component of bone, use of hydroxyapatite for this purpose brings a major brea...

Calcium ion concentration ([Ca2+]) in the systemic extracellular fluid, ECF-[Ca2+], is maintained around a genetically predetermined set-point, which combines the operational level of the kidney and bone/ECF interfaces. The ECF-[Ca2+] is maintained within a narrow oscillation range by the regula...

Teriparatide (PTH 1-34, Forsteo®) is a bioactive N-terminal fragment of the native endogenous parathyroid hormone (PTH 1-84) recommended for the treatment of osteoporosis in patients with high risk of fracture. Since PTH 1-34 may undergo proteolysis we have validated an ultra-high pressure liqui...

Inhibitory activity of a congeneric set of 23 phenyl-substituted 5-phenyl-pyrazole-3-carboxylic acids toward human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms I, II, IX and XII was evaluated by a stopped-flow CO2 hydrase assay. These compounds exerted a clear, selective inhibition of hCA IX an...

A novel series of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids has been synthesized and tested in vitro towards human protein kinase CK2. It was revealed that the most active compounds inhibiting CK2 are 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid and 3...

N-ε-lithocholyl lysine (NELL) is a component of tissue-bound lithocholic acid (TBL). The isolation of NELL from native protein sources was simulated by hydrolysis of lithocholyl-bovine serum albumin (BSA) (synthesized by coupling lithocholyl-N-hydroxysuccinimide to fatty acid-free BSA) by diges...

Furan-, thiophene- and N-methylpyrrole-2-carboxaldehydes may be transformed into the corresponding N,N'-dimethylimidazolidines in a reaction not requiring acid catalysis. The resulting furan and thiophene (but not N-methylpyrrole) derivatives may be metallated in high yields [predominantly ...