Our previous study revealed that the 2α-substituted vitamin D analog 2α-[2-(tetrazol-2-yl)ethyl]-1α,25(OH)2D3 (AH-1) exhibited a higher osteocalcin promoter transactivation activity in human osteosarcoma cells and a greater effect on bone mineral density in a rat model of osteoporosis than 1α...

24-Hydroxylated derivatives were synthesized in 24(R) and 24(S) forms by the convergent method as analogs related to 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3. In the convergent synthesis, the A-ring fragment, synthesized from diethyl D-tartarate, and the C/D-ring fragments in 24(R) and ...

The kinetics of oxidation of cyclohexanone (CAS 108-94-1) was studied experimentally in a fused silica jet stirred reactor (JSR) for the first time. The experiments were performed in the temperature range 530–1220 K, at an operating pressure of 10 atm, for equivalence ratios ranging from 0.5 to...

Cyclohexanone was identified as an attractive second-generation biofuel that can be used as an alternative fuel or blending component, thereby reducing greenhouse gas and particulate emissions from internal combustion engines. This paper investigates auto-ignition characteristics of cyclohexanon...

The Suzuki-Miyaura palladium-catalyzed coupling reaction was extended to achieve mixed cross-coupling between substituted aryl and naphthyl mono- and bisbromomethanes with phenylboronic acid, 1-methoxy-2-naphthyl-, 3-methoxy-2-naphthyl-, or 4-methoxy-1-naphthylboronic acid to form the correspond...

In an attempt to arrive at more potent cytotoxic agent than the bioactive natural product betulinic acid, influence of small structural modifications of its 1, 2, 3 triazole derivatives tethered at C-28 and both C3, C-28 using click chemistry approach has been studied. The chemically characteriz...

Biaryl phosphites derived from deoxycholic acid were used as chiral ligands in the asymmetric Suzuki–Miyaura cross-coupling of arylboronic acids with aryl bromides. Amongst the different reaction parameters, the role of the base emerged as being crucial for the outcome of the reaction: the choi...

The genes xpk1 and xpk2(Δ1–21) encoding phosphoketolase-1 and (Δ1–7)-truncated phosphoketolase-2 have been cloned from Lactobacillus plantarum and expressed in Escherichia coli. Both gene-products display phosphoketolase activity on fructose-6-phosphate in extracts. A N-terminal His-tag cons...

In the present work the structural, electronic, optical and magnetic properties of pure cubic HfO2and 3d transition metal (Mn, Fe, Co, Ni) doped (Hf1-xTMxO2) alloys (x = 0.25%) have been investigated by Density Functional Theory (DFT) as implemented in the FP-LAPW (full-potential augmented plane...

The atomic packing structure of Al90.5Y9.5, Al89.5Fe4.5Y6, Al85.5Ni9.5Y5, Al89Co5.5Y5.5 and Al85.5Co9.5Y5 metallic glasses (MGs) was studied using the extended X-ray absorption fine structure (EXAFS) technique, and the atomic packing efficiency (APE) of solute-centered clusters was calculated. T...

We have investigated the electronic structures of Y1-xTmxB6 (x = 0, 0.25) and Yb1-xTmxB6 (x = 0, 0.2) by means of hard x-ray photoemission spectroscopy (HAXPES) at h ν = 5.95 keV. The Tm 3d HAXPES revealed that the valence of Tm in YB6 is ∼2.6 at 300 K and ∼2.5 at 20 K, indicating strong vale...

Hydrothermal process was employed to synthesize the Yb3+/Tm3+, Yb3+/Ho3+ and Yb3+/Tm3+/Ho3+ doped BaMoO4 octahedron microcrystals (0.50–5.0 µm). The synthesized phosphors have scheelite tetragonal structure. The elemental mapping suggests the uniform distribution of elements in the samples. Th...

The structure and hydrogen adsorption properties of linear HCC-TMH (TM = Sc–Ni) complexes were systematically investigated using a density functional method. The ground states of the HCC-TMH (TM = Sc–Ni) complexes are 2, 3, 4, 3, 4, 3, 2, and 3. The gravimetric H2 uptake capacities of these gr...

Tm doped AlN (AlN:Tm) nanostructures such as nanowalls and hexagonal nanopillars were synthesized by plasma-assisted direct nitridation method without any catalyst or template. The AlN:Tm nanowalls exhibit strong photoluminescence in blue (460–480 nm), while nanopillars show strong emission lin...

This paper aims to offer a critical reflection on the way Talent Management (TM) is investigated in practice, by addressing the key issues regarding the quality (in terms of rigor and relevance) of academic empirical TM research and therefore the critical scrutiny of TM scholars’ work. We will ...

The motivation of this work was to produce TL dosimeters based on crystals of CaSO4 doped with thulium and silver, by means of a suitable new route. The crystals were produced by an adaptation of the slow evaporation route using calcium carbonate (CaCO3) as precursor, and incorporating the dopan...

The present study exhibits the enhancement of photocatalytic activity of transition metal (TM) doped ZnO (Zn1-xTMxO, with TM = Fe, Co, Ni) towards aqueous solution of organic dyes such as methylene blue (MB) under ultraviolet and visible light irradiation. Wurtzite Zn1-xTMxO nanoparticles are sy...

Two kinds of metal-organic frameworks (MOFs) based on Co (II) and Fe (II) as metal ions and trimasic acid (TMA) as organic linker were synthesized. They were used to prepare corresponding MgH2-TM MOF (TM = Co, Fe) composites via ball-milling. X-ray diffraction analyses show the formation of Mg2C...

The complex of tetrachloroplatinate and rhodamine-123, Pt(Rh-123)2 has demonstrated cytotoxic and antitumor effects and radio sensitizing potential in vitro and in vivo. Using the FSaIIC in vivo-in vitro tumor system, tumor cell survival indicated a dose modifying factor (DMF) of 1.51 due to the...

The platinum(II) tetrachlorodianion and two molecules of rhodamine-123 associate to form a neutral tight ion pair. To examine the intracellular fate of this ionic complex, the levels of uptake after a 1-hr exposure to a 100 μM concentration of each component of the complex, the complex itself a...