RésuméL'emploi de la méthode de tritiation par l'acide iodhydrique marqué nous a permis de réaliser la synthèse des hormones thyroïdiennes, thyroxine et 3:5:3′ tri-iodothyronine, tritiées en α-β de la chaîne alanine. Pariodation de la 3:5:3′ tri-iodothyronine doublement marq...

Increasing evidence suggests that plant polyphenolic compounds may protect from cardiovascular diseases, which have been addressed to their antioxidative properties. In addition, these compounds have been shown to possess anti-inflammatory and anti-microbial potential. In the present study we te...

This study investigated the mechanism of cytotoxicity of octyl (G8) and dodecyl (G12) gallates in a murine melanoma cell line (B16F10). For this purpose, several methods to measure cell viability were used to determine if the cytotoxicity induced by these gallates corresponds to a general or an ...

The effects of gallic acid (3,4,5-trihydroxybenzoic acid) and its alkyl esters on virus growth and virion infectivity were examined. All the compounds tested showed an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. The antiviral activity of gallic ...

Antifungal activities of propyl (C3), octyl (C8) and dodecyl (C12) gallates (3,4,5-trihydroxybenzoate) were tested against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483. Octyl gallate was found to be the only active compound with the minimum fungicidal concentration o...

The objective of this study was to investigate the possibility of using octyl gallate alone or with organic biocides as a preservative against wood decay fungi. Antifungal activities of three antioxidants, propyl gallate, octyl gallate and butylated hydroxyltoluene (BHT) were tested against four...

Pluronics have emerged as a potential agent for solubilizing a variety of lipophilic bioactive molecules, but how these solubilizates affect the morphology of Pluronic micelles still remains poorly understood. In this work, the morphological transition of Pluronic P123 micelles induced by three ...

Herbal medicines stand unique and effective in treating human diseases. Terminalia bellarica (T. bellarica) is a potent medicinal herb, with a wide range of pharmacological activities. The present study was aimed to evaluate the effect of octyl gallate (OG) and gallic acid (GA) isolated from met...

Octyl gallate (OG) is an internationally recognized antioxidant that demonstrates selective and sensitive fluorescent property. The fluorescence of OG can be selectively enhanced in the presence of human serum albumin (HSA) and bovine serum albumin (BSA). The specific structures of HSA and BSA p...

Octyl gallate (OG) is an antioxidant that has shown anti-tumor, anti-diabetic and anti-amyloidogenic activities. Mitochondria play an important role in hepatocellular carcinoma, mainly by maintaining accelerated cellular proliferation through the production of ATP. Thus, the mitochondria may be ...

Glyoxal (GO) is one of the major toxic intermediates generated during lipid oxidation and degradation. We investigated the inhibitory activities and mechanisms of propyl, octyl, and dodecyl gallates (PG, OG, and DG) on the formation of GO in buffer and during thermo-processing of corn oil, and t...

The fluorescence decay from S2(π, π*) state of 2,5-diphenyl-1,6,6a-trithiapentalene (DP-TTP) in cyclohexane, tetrahydrofuran and acetonitrile solutions of a quantum yield of ∼0.02–0.04 were measured. The results indicate that, the dominant process of radiationless deactivation of the S2 stat...

In this study, the structural molecular geometry, vibrational frequencies (FT-IR and Raman), 1H and 13C NMR (Nuclear Magnetic Resonance) chemical shifts and UV–Vis. spectral parameters of (adamantan-1-yl)(phenylsulfanyl)methanone (C17H20OS) were investigated using experimental and theoretical m...

The dipole moments of four 2,6-dinitrophenyl R'-phenyl (R' = H, 2'-F, 2'-Me and 2'-I), four 2,6 dinitro-4-chlorophenyl R'-phenyl (R' = 2'-F, 2',4'-Cl2, 2'4'-Br2 and 1'-naphthyl) and five 2,4-dinitronaphthyl R'-phenyl (R' ...

Catalytic synthesis of potential chemosensor 2-(1H-Benzimidazol-2-yl)phenol (HBYP) has been prepared by three components cyclization reaction. It can behaves as a selective fluorescent sensor for the detection of Fe3+ metal ion. HBYP has been characterized by 1H NMR, 13C NMR, mass spectral studi...

During the analysis of “seized samples”, suspected of containing 4-methylmethcathinone (mephedrone) and N-ethylcathinone (ethcathinone) additional compounds were observed in the GCMS chromatogram. These compounds were suspected to be the corresponding phenylacetone isomers of mephedrone and et...

We have studied the differential effect of dimethyl-10,12-benz(a)acridine (DMBAcr) on the synthesis of RNA of chicken or mouse fibroblasts in culture and that of some RNA-containing viruses such as Rous sarcoma virus and Mengovirus.DMBAcr at low concentrations blocks the cell multiplication of b...

5-Mercapto-3-phenyl-1,3,4-thiadiazole-2-thione potassium (MPTT) self-assembled monolayer (SAM) on copper surface has been investigated by FT-IR and contact angle (CA) and the results showed that MPTT was adsorbed on copper surface and yielded a hydrophobic film. The inhibition effect of MPTT SAM...

Triamiphos (3-phenyl-5-amino-1,2,4-triazolyl-(1)-(N,N'-tetramethyl), diamido phosphonate) is an acaricide, insecticide and systemic fungicide. Being a phosphoric ester it has cholinesterase-inhibiting properties. In a long-term feeding study over 2 years and a 3-generation reproduction stud...

The i.p. LD5 0 of the organophosphorus ester triamiphos to adult male rat is about 15 mg/kg. The symptoms are typical of peripheral cholinesterase inhibition. Thus death is due to respiratory paralysis; there is no stimulation of the central nervous system. Measurement of the cholinesterase acti...