In terms of its oxidative strength, the MnO2/Mn2+ couple is one of the strongest in the aquatic environment. The intermediate oxidation state, manganese(III), is stabilized by a range of organic ligands (Mn(III)-L) and some of these complexes are also strong oxidants or reductants. Here, we pres...

The specific surface area of 9 industrial flue gas desulphurization (FGD) gypsum samples was measured by the adsorption of nitrogen (BET isotherm), mercury intrusion porosimetry and the adsorption of methylene blue from aqueous solution. The results were compared with the reactivity of the studi...

In this paper, nanoparticles of delafossite-type LiCo0.5Fe0.5O2 were prepared by sol–gel method in the presence of maleic acid as a chelating agent. The nanoparticles were characterized using differential thermal analysis, X-ray powder diffraction, Fourier infrared spectroscopy, transmission el...

In the present study, nanoparticles of perovskite-type La0.5Ca0.5NiO3 − δ (LCNO) were fabricated by sol–gel method in the presence of nitrate–metal–ethylene glycol (EG) polymerized complex. A series of analytical techniques were used to characterize the crystallinity, morphology, specific su...

Two halotolerant bacteria isolated from water samples of saltpan located at Ramanathapuram district, Tamil Nadu and tested their dye decolourization efficiency against four textile dyes. Of the tested strains, strain CMR2 showed maximum decolourization (98%) for Reactive Blue EFAF within 24 h. F...

The aim of this work was to evaluate the catalytic activity of new Au-Fenton-like catalyst in degradation of methylene blue at ambient conditions. For this purpose gold nanoparticles were deposited on commercial ZnO and the material prepared in this way was characterized with N2-adsorption and d...

N-(2-methyl-5-chlorophenyl)salicylaldimine (C14H12ClNO) has been studied by X-ray analysis and AM1 molecular orbital methods. It crystallises in the orthorhombic space group P212121 with a = 7.474(1) Å, b = 12.155(1) Å, c = 13.378(1) Å, V = 1215.3(2) Å3, Z = 4, Dc = 1.343 g cm−3 and μ(Mo Kα...

With the aim to reduce multidrug resistance several molecules were synthesized and tested for their ability to inhibit ATP-binding cassette (ABC) proteins, which are responsible for drugs transport out from cells. The compound 8-(4-chlorophenyl)-5-methyl-8-[(2Z)-pent-2-en-1-yloxy]-8H-[1,2,4]oxad...

Previous research studies confirm that molecules containing 1,2,3-triazole moiety are potential anticancer agents which elevates effectiveness and reduces drug resistance. Present study was aimed to evaluate the anticancer activity of the synthesized novel title compound 2-(1-benzyl-5-methyl-1H-...

We previously demonstrated that glucagon-like peptide-2 (GLP-2) exerted antidepressant-like effects in mice. The aim of the present study was to investigate the relationship between N-methyl-D-aspartate (NMDA) receptor-nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway and the antidep...

The investigation of the glassy state of 5-ethyl-5-methylhydantoin (i.e. 12H, a chiral Active Pharmaceutical Ingredient) was attempted by Differential Scanning Calorimetry (DSC) and Fast Scanning Calorimetry (FSC). This compound exhibits a high crystallization propensity for every enantiomeric c...

A set of novel diarylisoxazoles has been projected using mofezolac (1) as a lead compound to investigate structure-inhibitory activity relationships of new compounds and the cyclooxygenases (COXs) catalytic activity. Mofezolac was chosen because is the most potent and selective reversible COX-1 ...

Activation of central 5-hydroxytryptamine (5-HT4) receptors may enhance cognitive performance. In the present study, the effects of two novel, potent and selective 5-HT4 receptor agonists, RS 67333 (1-(4-amino-5-chloro-2-methoxyphenyl)-3-(1-n-butyl-4-piperidinyl)-1-propanone) and RS 67506 (1-(4-...

We have previously reported phenylpropan-2-one (most commonly known as phenyl-2-propanone, P2P) and methamphetamine derived by-products formed in the Baeyer-Villiger route starting from benzaldehyde. This route is a three step synthesis to P2P; an aldol condensation of benzaldehyde and methyl et...

Pantethine [d-bis-(N-pantothenyl-β-aminoethyl)-disulfide] is a compound used clinically to decrease plasma triglycerides and to increase HDL cholesterol. To understand the mechanism of action of this drug, its effect on the synthesis of cholesterol in cultured skin fibroblasts was assessed. The...

Pantethine (d-bis-(N-pantothenyl-β-aminoethyl)-disulfide, PAN), the stable disulfide form of pantetheine, has beneficial effects in vascular diseases being able to decrease the hyperlipidaemia, moderate the platelet function and prevent the lipid peroxidation. Furthermore, recent studies sugges...

Safety and efficacy of a biologically active derivative of vitamin B5 (pantethine) on total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) metabolism was studied in North American subjects at conventional low to moderate cardiovascular disease (CVD) risk. A total of 120 subject...

BackgroundNew, safer, and more effective agents to treat hyperlipidemia and thereby prevent cardiovascular events are under research.

Three different types of Ag2+ ions (“a”, “b”, and “c”) have been identified and examined by electron paramagnetic resonance (EPR) on 10% wt Ag/CeO2 prepared by impregnation method. One of them, Ag2+(b), behaves differently than the two others, Ag2+(a) and Ag2+(c), under redox atmospheres. ...

Perylene diimides (PDIs) have been used in various industries, especially in devices such as organic light-emitting diodes, organic semiconductors, and thin-layer organic photovoltaics, because of their excellent optical and electrical properties and outstanding thermal stability. In addition, P...