SummaryObjectivesPain and disability are the main clinical manifestations of osteoarthritis, for which only symptomatic therapies are available. Hence, there is a need for therapies that can simultaneously alter disease progression and provide pain relief. KBP is a dual amylin- and calcitonin-re...

Salmon calcitonin phospholipid complex loaded-solid lipid nanoparticles (sCT-PC-SLNs) were prepared from Salmon calcitonin phospholipid complex (sCT-PC) by a film dispersion method. The formulation was optimized by the Box-Behnken response surface design using quality properties such as particle...

Osteoporosis is the most common metabolic bone disease, which poses an immense socio-economic burden on the society. Human calcitonin, though safe, is not considered as a therapeutic option because of its high tendency to self-associate to form amyloid fibrils thereby affecting its potency. To c...

Porous starch xanthate (PSX) and porous starch citrate (PSC) were prepared in anticipation of the attached xanthate and carboxylate groups respectively forming chelation and electrostatic interactions with heavy metal ions in the subsequent adsorption process. The lead(II) ion was selected as th...

A novel crosslinked starch-graft-polyacrylamide-co-sodium xanthate (CSAX) was synthesized by grafting copolymerization reaction of corn starch, acrylamide (AM), and sodium xanthate using epichlorohydrin (EPI) as cross-linking reagent and ceric ammonium nitrate (CAN) as initiator in aqueous solut...

From June 1987 to June 1995, 200 patients with various types of head and neck lymphangioma were treated by intratumorous injection of bleomycin-A5. All 200 cases were followed from 2 to 10 years; 95 cases were followed for more than 5 years. The effective rate was 97%, and the curative rate was ...

ObjectivesTo evaluate the therapeutic outcome of ultrasound-guided intralesional injection of bleomycin A5 on treatment of venous malformation (VM) in cervical-facial region.

DNA is the potential target of numerous drugs utilized widely in clinical cancer therapy. Here we employed bleomycin A5, with its deactivated form as contrast, to investigate the interaction between small pharmaceutical and DNA. Electrophoresis mobility shift assay (EMSA) which is a common techn...

ObjectiveThe purpose of this study was to evaluate the efficacy of bleomycin A5 (pingyangmycin) plus dexamethasone for control of growth in infantile parotid hemangiomas.

ObjectivesThe purpose of this study was to document the results of bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations (LMs), and the clinical data of 65 patients between October 2004 and October 2007 were reviewed.

ObjectiveBleomycin A5 has been reported effective for infantile haemangioma (IH), but the usage and complications were described a little. We have used bleomycin A5 to treat maxillofacial IHs for 15 years. This paper describes the procedures to use bleomycin A5 and avoid its complications based ...

A dynamic model was developed for a single reactor tube, in which methanol oxidation to formaldehyde over an iron molybdate/molybdenum oxide catalyst takes place simultaneously with transport of MoO3 from the catalyst through the reactor. A previously developed dynamic 1D mathematical model for ...

Refractive index modulation in optical materials facilitates dynamic control on electromagnetic waves. Ultra fast tuning of both refractive index and its spatial distribution in Y−Z Lithium Niobate slab via strain employed through GHz acoustic perturbation has been simulated and studied. To crea...

The grating coupler on single-crystal lithium niobate thin film (lithium niobate on insulator, LNOI) was designed. A bottom reflector was added in the LNOI material to improve the coupling efficiency. The grating structure was optimized by FDTD method. The material parameters such as layer thick...

We propose a DC-based polarization beam splitter (PBS) in lithium niobate on insulator (LNOI). Utilizing the high birefringence property of Lithium Niobate (LiNbO3, LN), the device is achieved by simple structure in a short length. With the use of beam propagation method (BPM), the simulation re...

A multi-wavelength tunable filter is designed. It consists of multiple waveguides among multiple waveguide gratings. A pair of electrodes were placed on both sides of each waveguide. The tunable filter uses the electro-optic effect of Lithium Niobate to tune the phase caused by each waveguide. C...

According to optical absorption spectra the width of the forbidden band of nominally pure congruent and stoichiometric lithium niobate crystals, as well as a series of congruent crystals doped with cations of Mg2+(0.35 wt.%), Zn2+(2.05), B3+(0.12), Gd3+(0.26, 0.44, 0.51), Y3+(0.46), Gd3+(0.23):M...

Power dissipation is an important consideration in digital design. Reversible logic is an unconventional form of computing in which the computational process is bijective and can efficiently reduce power dissipation problem. Peres gate is a basic reversible logic gate used in various reversible ...

Erbium-activated lithium niobate; 1, 2, and 4 mol% (LN-1, LN-2 and LN-4 respectively) were synthesized by solid-state method and their thermoluminescent (TL) properties were analyzed. The glow curve of LN-4 showed a maximum at 177 °C and its linear dose-response interval ranged from 50 to 350 G...

The influence of pre-annealing of lithium niobate in the range of 400–800 °C was studied at each step of formation of proton-exchange waveguides. Pre-annealing affects the structure and optical properties of lithium niobate. There is a relationship between the initial structure of lithium niob...