Sudan III [1-{[4-(phenylazo) phenyl]azo}-2-naphthalenol] is non-ionic fat-soluable dye used as an additive in gasoline, oils and plastics. The molecular structure, molecular electrostatic potential, NBO analysis, linear and non-linear optical properties of Sudan III have been investigated using ...

The design and synthesis of 10-(2-benzoxazolcarbonyl)-DDACTHF (1) as an inhibitor of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide transformylase (AICAR Tfase) are reported. Ketone 1 and the corresponding alcohol 13 were evaluated for inhibition of GAR Tfas...

Purpose: To detect possible interactions between ()-formyl-tetrahydrofolic acid (leucovorin, ()-fTHF) and (+)-formyl-tetrahydrofolic acid ((+)-fTHF) on the plasma and intracellular pharmacokinetics following their simultaneous administration. Methods: Plasma levels of ()-fTHF, ()-methyl-THF, and...

The synthesis of 10-formyl-DDACTHF (3) as a potential inhibitor of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide ribonucleotide transformylase (AICAR Tfase) is reported. Aldehyde 3, the corresponding γ- and α-pentaglutamates 21 and 25 and related agents w...

. Hydroflumethiazide was determined from the chemiluminescence produced in its reaction with Ce(IV) in acidic medium containing rhodamine 6G as a sensitizer using flow injection techniques (stopped flow mode). A straightforward automatic method based on measuring the peak height and peak area, w...

In vitro experiments were designed to assess the inhibitory effect of the thiazide diuretic methyclothiazide (MCTZ) on contractile responses to norepinephrine (NE) of mesenteric rings from hypertensive patients and normotensive controls. Arteries were taken from portions of mesocolon from 24 pat...

Data concerning a vasorelaxant direct action of thiazide diuretics are scarse and controversial. The aim of the present work was to assess and to compare the vascular relaxation induced by indapamide (I), methyclothiazide (MT) and hydrochlorothiazide (H).Aortas from spontaneously hypertensive a...

A quantitative high-performance liquid chromatographic method in which amiloride is separated from methylclothiazide on a C 18 column with detection at 286 nm was developed with the aid of the ‘window diagram’ technique of Laub and Purnell. The effect of simultaneously varying the pH a...

Sprague-Dawley rats were administered 1,2-diethylbenzene (1,2-DEB) by gavage on gestational days (GD) 6 through 20 at dose levels of 0 (corn oil), 5, 15, 25 or 35mg/kg. The dams were euthanized on GD21 and the offspring were weighed and examined for external, visceral and skeletal alterations. M...

The bio-distribution of the neurotoxic 1,2-diethylbenzene (1,2-DEB) was studied in male Sprague-Dawley rats after intravenous administration of [14C] 1,2-DEB (1 mg kg−1). The highest concentrations of [14C] non-volatile metabolites, determined by whole-body auto-radiography, were in the nasal ca...

1,2-Diethylbenzene (1,2-DEB) is used in the manufacture of some plastics. Exposure to 1,2-DEB has been shown to induce peripheral neuropathy in rats. This neurotoxicity is thought to be caused by a metabolite, 1,2-diacetylbenzene (1,2-DAB), a γ-diketone-like compound. 1,2-DEB was previously sho...

Vanillin and syringaldehyde are widely used as flavoring and fragrance agents in the food products. The potential of a macro-mesoporous adsorption resin was assessed for separation of these binary mixtures. This work focuses on modeling of the competitive adsorption behaviors and exploration of ...

The recovery of purified fractions of vanillin and syringaldehyde (V&S) from an oxidized lignin medium has attracted considerable attention driven by the high added value of these products and the importance of lignin valorization processes in biorefineries. Polymeric resins with high specific a...

This paper reports on an approach for separating vanillin and syringaldehyde (VSA) from oxygen delignification spent liquor using non‐polar macroporous resin. The effects of temperature and pH on the adsorption isotherms were studied. The adsorption capacity and adsorption equilibrium constant ...

Formal potentials (expressed on the ferrocene scale) for the formation of 4-chlorobenzophenone anion radicals E R X / R X - o as well as for the Cl /Cl - couple increase with the solvent acceptor number but the second dependence is at least twice as ...

4-Methylbenzophenone crystallizes in a monoclinic stable form (mp 59 o C) with a = 5.70 a, b = 13.89 a, c = 14.08 a, β = 95.18 o and space group P2 1 /c, and a trigonal metastable form (mp 55 o C) with a = 9.12 a, c = 11.28 a and space groups P3 1 or P3 ...

Benzophenone (BP) and 4-methylbenzophenone (4MBP) are photo-initiators that are generally used to cure ink on carton boards.In this contribution, a fast and reliable method for the determination of BP and 4MBP in breakfast cereals is described. The sample was extracted ultrasonically using a mix...

4-Benzoylbenzyl-3-morpholinopropanoate was synthesized, characterized and used as a one-component photoinitiator of Type II. Real-time near-IR spectroscopy was used to study the kinetics of conversion of double bonds of monomers vs. irradiation time. In this initiator, the radicals could be gene...

The density functional theory (DFT) calculations were performed on benzoin (BN), benzil (BL), benzoin-(4-phenylthiosemicarbazone) (BN4PTSC) and benzil-(4-phenylthiosemicarbazone) (BL4PTSC) used as corrosion inhibitors for mild steel in acidic medium. The quantum chemical parameters/descriptors, ...

Benzil and its derivatives naphthil and pyridil have been found to undergo a dianionic oxy‐Cope rearrangement upon reaction with 2‐lithio‐4,5‐dihydrofuran to give 3,3′‐octahydrobifuranyls selectively as the meso diastereomers. The diastereoselectivity is explained based on the reaction mec...