Catalytic reduction of aromatic ketones is an interesting reaction that leads to the obtaining of alcohols. Some of these alcohols are employed as intermediaries to produce chemical fine compounds. The bimetallic catalysts are widely used in the chemoselective hydrogenation. The Surface Organome...

A novel and efficient In(OTf)3 and HOAc cooperatively catalyzed hydration of 1-haloalkynes is described. This method provides ready access to α-chloromethyl ketones, α-bromomethyl ketones and α-iodomethyl ketones in moderate to high yields from simple, inexpensive starting materials. A broad ...

A copper catalyzed asymmetric tandem double Michael addition of diethylzinc to α,β-unsaturated ketones followed by trapping with nitroolefins has been developed using chiral P,N-ligands. The tandem products were obtained in good yields and excellent enantioselectivities with three contiguous s...

We have developed a robust ruthenium (II) complex catalyst coordinated by chiral Schiff bases for the reduction of acetophenone by ATH in water. The results show a significant effect of the nature of the chiral entity on the reactivity and the selectivity of the catalytic system. The Schiff base...

As the completion of the third installment in the series of reviews of the literature on blocked isocyanates, Parts A and B of this review bring together the most important developments documented in over 1700 patents and publications that have been printed between 1980 and mid-2000. For referen...

Monolignol glucosides and their β-glucosidases are found in monocots, but their biological roles are unclear. Phylogenetic analysis of rice (Oryza sativa L.) glycoside hydrolase family GH1 β-glucosidases indicated that Os4BGlu14, Os4BGlu16, and Os4BGlu18 are closely related to known monolignol...

2,4-Dinitrophenyl 2-acetamido-2-deoxy-β-d-glucopyranosyl-(1→4)-2-deoxy-2-fluoro-β-d-glucopyranoside (GN2FG-DNP) and 2-acetamido-2-deoxy-β-d-glucopyranosyl-(1→4)-2-deoxy-2-fluoro-β-d-glucopyranosyl fluoride (GN2FG-F) were prepared using a divergent synthetic approach involving 10 steps. The...

The diffusivity and solubility of carbonyl sulfide at temperatures from (313.15 to 353.15) K and pressures up to about 1.0 MPa and also the solubility of sulfur dioxide at the same temperatures and low pressures ranges in ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethyl) sulfonylimid...

Ternary liquid-liquid equilibria were experimentally determined for eight systems composed of an ionic liquid + n-hexane + an organic compound implicated in the racemic resolution of rac-2-pentanol (rac-2-pentanol, vinyl butyrate, rac-2-pentyl butyrate or butyric acid) at a temperature of 303.15...

25 patients with residual or recurrent ovarian cancer were treated with the new platinum complex zeniplatin (CL 286,558) and 23 patients were evaluable for response. Responses were achieved in 4 patients, 1 complete and 3 partial remissions (16%). 7 patients had stable disease and 12 patients ha...

A method is presented for the determination of tetrachlorobenzyltoluenes (TCBTs) in fish. TCBTs represent the major constituents of Ugilec, which is commonly used as a substitute for polychlorinated biphenyls (PCBs) in underground mining. The compounds are extracted from the freeze-dried materia...

In vitro biotransformation rates of tetrachlorobenzyltoluene (TCBT) isomers 3,3′,4,4′-Cl4-2-Me (TCBT 87), 3,3′,4,4′-Cl4-5-Me (TCBT 88), and 3,3′,4′,5-Cl4-4-Me (TCBT 94) were determined using trout and rat hepatic microsomes. The disappearance of the TCBTs from the in vitro system followed ...

The toxicity of the PCB substitute Ugilec 141, a mixture of tetrachlorobenzyltoluenes (TCBTs), is compared with the toxicity of a commercial mixture of polychlorobiphenyls (Aroclor 1254) and with the model toxic PCB-congener 3,3′,4,4′,-tetrachlorobiphenyl (PCB-77) as a positive control. Altera...

Ugilec-141® is a PCB substitute based on chlorinated benzyltoluenes which has been reported as an environmental contaminant in some German rivers. It is structurally similar to some phenylxylylethanes which induce hepatic microsomal mono-oxygenases in fish. When injected i.p. into dab (Limanda l...

The biological resistance of methicillin-resistant staphylococcus aureus (MRSA) has pushed synthetic antibiotics to the forefront. To combat the resistance of MRSA, our new effort directed towards the development of novel structural candidates of enone-bridged indole nitroimidazole scaffolds, an...

Several novel sulfonyl chloride functionalized ionic materials were used as media and catalysts for Beckmann rearrangement of cyclohexanone oxime and satisfactory results were achieved under mild conditions. The effects of all parameters were discussed. Moreover, the deactivation of ionic liquid...

para-Regioselective bromination of phenol and analogues, promoted by p-toluenesulfonic acid, is achieved in high to excellent yields at room temperature with N-bromosuccinimide. Chlorination with N-chlorosuccinimide and catalysed by p-toluenesulfonic acid also gives para-chlorinated phenol analo...

A stereoselective and enantiodivergent strategy for the construction of δ-lactams is described. The strategy utilizes chiral malonic esters prepared from enantiomerically enriched mono esters of disubstituted malonic acid. A cyclization occurs with the selective displacement of a substituted be...

In order to investigate the effect of trifluralin, pronamide, haloxyfop-p methyl, propaquizafop and isoxaben on weed control and oilseed rape yield, a two year field experiment was conducted at Darab, Iran, during 2004–2005 and 2005–2006 growing seasons. Herbicides reduced weed biomass compare...

Experiments were conducted to evaluate potential interactions between propaquizafop and pyrithiobac applied in mixture or in sequential applications on green foxtail (Setaria viridis) and bristly foxtail (Setaria verticillata). The effect of propaquizafop application rate and the effect of ammon...