Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:121602-93-5
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryhigh quality Appearance:Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Intermediates Transportation:by air or by sea Port:Shanghai, Qingdao
Cas:121602-93-5
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:121602-93-5
Min.Order:1
Negotiable
Type:Other
inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
Cas:121602-93-5
Min.Order:1 Kilogram
FOB Price: $5.0
Type:Manufacturers
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis
Cas:121602-93-5
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:121602-93-5
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryCSA NO.:121602-93-5 3,4,5-Trifluorobenzoic acid 1.Large qty in stock 2.High quality 3.Lowest price 4.Best service Our Advantage 1. Risk-free guarantee,15days refund 2. Most of the products in stock,can ship within 7days after the
Cas:121602-93-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:121602-93-5
Min.Order:1 Gram
FOB Price: $6.0 / 9.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:121602-93-5
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryProduct Name: 3,4,5-Trifluorobenzoic acid CAS: 121602-93-5 MF: C7H3F3O2 MW: 176.09 EINECS: 624-063-4 Mol File: 121602-93-5.mol 3,4,5-Trifluorobenzoic acid Structure 3,4,5-Trifluorobenzoic acid Chemical Properties Melting point
Cas:121602-93-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:121602-93-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:121602-93-5
Min.Order:5 Gram
FOB Price: $675.0
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryProduct name: 3,4,5-Trifluorobenzoic Acid CAS No.:121602-93-5 Molecule Formula:C7H2F3O2 Molecule Weight:175.09 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TES
Cas:121602-93-5
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:121602-93-5
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAcmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:121602-93-5
Min.Order:1 bottle
Negotiable
Type:Lab/Research institutions
inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:121602-93-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirycarbon dioxide
3,4,5-trifluoro-1-bromobenzene
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With n-butyllithium In diethyl ether; hexane at -75℃; for 0.25h; | 93% |
Stage #1: 3,4,5-trifluoro-1-bromobenzene With magnesium Metallation; Stage #2: carbon dioxide Carboxylation; Grignard reaction; |
4-Fluorobenzoic acid
A
2,3,4,5-tetrafluorobenzoic acid
B
3,4-Difluorobenzoic acid
C
2,4,5-trifluorobenzoic acid
D
2,3,4,-trifluorobenzoic acid
E
3,4,5-trifluorobenzoic acid
F
2,4-difluoro-benzoic acid
Conditions | Yield |
---|---|
With fluorine In sulfuric acid Product distribution; various substrate to fluorine ratios; also in 98percent HCOOH; |
Pentafluorobenzoic acid
A
2,3,4,5-tetrafluorobenzoic acid
B
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With 1,10-Phenanthroline; nickel dichloride; zinc In water; N,N-dimethyl-formamide at 50℃; for 6h; Product distribution; Further Variations:; Reagents; Temperatures; reaction time; Hydrodefluorination; |
1,2,3-trifluorobenzene
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 91 percent / sec-butyllithium / tetrahydrofuran; cyclohexane / 1.5 h / -75 °C 2: 95 percent / bromine / CCl4 / Heating 3: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 4: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 5: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 6 steps 1: 91 percent / sec-butyllithium / tetrahydrofuran; cyclohexane / 1.5 h / -75 °C 2: 95 percent / bromine / CCl4 / Heating 3: 67 percent / diisopropylamine; butyllithium; tetrabromomethane / hexane; tetrahydrofuran / 2 h / -75 °C 4: 92 percent / butylmagnesium chloride; butyllithium / tetrahydrofuran; hexane; toluene / 0.75 h / 0 °C 5: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 6: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: 91 percent / sec-butyllithium / tetrahydrofuran; cyclohexane / 1.5 h / -75 °C 2.1: 95 percent / bromine / CCl4 / Heating 3.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C 3.2: 75 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 4.1: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
1,2-dibromo-3,4,5-trifluorobenzene
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 2: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
1,5-dibromo-2,3,4-trifluorobenzene
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 2: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 3: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 4 steps 1: 67 percent / diisopropylamine; butyllithium; tetrabromomethane / hexane; tetrahydrofuran / 2 h / -75 °C 2: 92 percent / butylmagnesium chloride; butyllithium / tetrahydrofuran; hexane; toluene / 0.75 h / 0 °C 3: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 4: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C 1.2: 75 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 2.1: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
1,2,3-tribromo-4,5,6-trifluoro-benzene
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 92 percent / butylmagnesium chloride; butyllithium / tetrahydrofuran; hexane; toluene / 0.75 h / 0 °C 2: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 3: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
1-bromo-2,3,4-trifluorobenzene
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 92 percent / diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 2: 93 percent / bromine / CCl4 / 36 h / Heating 3: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 4: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 5: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 6 steps 1: 92 percent / diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 2: 93 percent / bromine / CCl4 / 36 h / Heating 3: 67 percent / diisopropylamine; butyllithium; tetrabromomethane / hexane; tetrahydrofuran / 2 h / -75 °C 4: 92 percent / butylmagnesium chloride; butyllithium / tetrahydrofuran; hexane; toluene / 0.75 h / 0 °C 5: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 6: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: 92 percent / diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 2.1: 93 percent / bromine / CCl4 / 36 h / Heating 3.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C 3.2: 75 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 4.1: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
(5-bromo-2,3,4-trifluorophenyl)triethylsilane
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 93 percent / bromine / CCl4 / 36 h / Heating 2: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 3: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 4: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 5 steps 1: 93 percent / bromine / CCl4 / 36 h / Heating 2: 67 percent / diisopropylamine; butyllithium; tetrabromomethane / hexane; tetrahydrofuran / 2 h / -75 °C 3: 92 percent / butylmagnesium chloride; butyllithium / tetrahydrofuran; hexane; toluene / 0.75 h / 0 °C 4: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 5: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: 93 percent / bromine / CCl4 / 36 h / Heating 2.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C 2.2: 75 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 3.1: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
2,3,4-trifluoro-1,5-phenylenebis(triethylsilane)
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 95 percent / bromine / CCl4 / Heating 2: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 3: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 4: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 5 steps 1: 95 percent / bromine / CCl4 / Heating 2: 67 percent / diisopropylamine; butyllithium; tetrabromomethane / hexane; tetrahydrofuran / 2 h / -75 °C 3: 92 percent / butylmagnesium chloride; butyllithium / tetrahydrofuran; hexane; toluene / 0.75 h / 0 °C 4: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 5: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: 95 percent / bromine / CCl4 / Heating 2.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C 2.2: 75 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 3.1: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme |
3,4,5-trifluoro aniline
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 2: Mg View Scheme |
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Stage #1: 3,4,5-trifluorobenzaldehyde With potassium permanganate In water; acetone at 20℃; for 6.5h; Stage #2: With hydrogenchloride; sodium hydrogensulfite In water; acetone |
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
In ethanol; dichloromethane at 25℃; Kinetics; |
methyl 3,4,5-trifluorobenzoate
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Stage #1: methyl 3,4,5-trifluorobenzoate With sodium hydroxide In methanol; water for 2h; Reflux; Stage #2: With hydrogenchloride |
di-tert-butyl dicarbonate
3,4,5-trifluorobenzoic acid
tert-butyl 3,4,5-trifluorobenzoate
Conditions | Yield |
---|---|
dmap In tert-butyl alcohol at 40℃; for 18h; | 100% |
4,4-difluorocyclohexanol
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 6h; | 100% |
tri(p-tolyl)antimony
3,4,5-trifluorobenzoic acid
(CH3C6H4)3Sb(OCOC6H2F3)2
Conditions | Yield |
---|---|
With dihydrogen peroxide In diethyl ether; water byproducts: H2O; react. of antimony compd. and acid with aq. H2O2 at room temp. in ether; elem. anal.; | 99% |
triphenylantimony
3,4,5-trifluorobenzoic acid
(C6H5)3Sb(OCOC6H2F3)2
Conditions | Yield |
---|---|
With dihydrogen peroxide In diethyl ether; water byproducts: H2O; react. of antimony compd. and acid with aq. H2O2 at room temp. in ether; elem. anal.; | 99% |
tri(p-tolyl)antimony
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With H2O2 In diethyl ether (C6F3H2)COOH and 30% aq. H2O2 added to soln. of (p-tolyl)3Sb in ether; kept at 20°C for 12 h; crystals filtered off; dried; elem. anal.; | 99% |
triphenylantimony
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With H2O2 In diethyl ether (C6F3H2)COOH and 30% aq. H2O2 added to soln. of Ph3Sb in ether; kept at 20°C for 12 h; crystals filtered off; dried; elem. anal.; | 99% |
3,4,5-trifluorobenzoic acid
2-(((tert-butyldimethylsilyl)oxy)methyl)-6-hydroxy-2H-pyran-3(6H)-one
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 1.5h; | 99% |
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With dmap In dichloromethane at 0℃; for 0.5h; Inert atmosphere; | 98% |
Conditions | Yield |
---|---|
In xylene mixt. of BiPh3 and 3,4,5-trifluorobenzoic acid in p-xylene stored in sealed tube in air for 16 h at 20°C; elem. anal.; | 97% |
Conditions | Yield |
---|---|
In benzene mixt. of BiPh3 and 3,4,5-trifluorobenzoic acid in benzene stored in sealed tube in air for 16 h at 20°C; elem. anal.; | 95% |
3,4,5-trifluorobenzoic acid
3,4,5-trifluoro-N-phenylbenzamide
Conditions | Yield |
---|---|
With iron(III)-acetylacetonate In o-xylene at 130℃; for 24h; Microwave irradiation; | 95% |
triphenylbismuthane
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
In benzene Reflux; | 93% |
3,4,5-trifluorobenzoic acid
2,6-difluorophenol
Conditions | Yield |
---|---|
With water; lithium carbonate at 180 - 185℃; for 12h; Sealed tube; | 92.1% |
oxygen
triphenylbismuthane
toluene
3,4,5-trifluorobenzoic acid
Bi4(O)2(O2CC6H2F3-3,4,5)8*2η6-toluene
Conditions | Yield |
---|---|
In toluene mixt. of Ph3Bi and 3,4,5-trifluorobenzoic acid in toluene kept in sealedglass tube with air (20°C, 16 h); crystals filtered off; dried; | 92% |
penta(p-tolyl)antimony(V)
3,4,5-trifluorobenzoic acid
tetra(p-tolyl)antimony 3,4,5-trifluorobenzoate
Conditions | Yield |
---|---|
In benzene at 80℃; for 1h; Sealed tube; | 91% |
triphenylbismuthane
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
In o-xylene byproducts: C6H6; mixt. of Ph3Bi and 3,4,5-trifluorobenzoic acid (1:2 molar ratio) kept (20°C, 16 h) in sealed glass tube containing atmospheric O2; crystals filtered off; dried; elem. anal.; | 90% |
6-hydroxy-3,6-dihydro-2H-pyran-3-one
3,4,5-trifluorobenzoic acid
5-oxo-5,6-dihydro-2H-pyran-2-yl 3,4,5-trifluorobenzoate
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 1.5h; Inert atmosphere; | 89% |
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 1.5h; | 58% |
Conditions | Yield |
---|---|
Stage #1: 3,4,5-trifluorobenzoic acid With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 3h; Inert atmosphere; Stage #2: carbon dioxide In tetrahydrofuran; hexane at -78 - 20℃; | 89% |
3-amino-N-cyclopropyl-4-methylbenzamide
3,4,5-trifluorobenzoic acid
N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-3,4,5-trifluorobenzamide
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In DMF (N,N-dimethyl-formamide) for 16h; | 88% |
3,4,5-trifluorobenzoic acid
benzyl alcohol
4-(benzyloxy)-3,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; | 88% |
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With dmap; copper diacetate In acetonitrile at 100℃; for 6h; Schlenk technique; Sealed tube; Inert atmosphere; | 85% |
1-bromo-2-(triisopropylsilyl)acetylene
3,4,5-trifluorobenzoic acid
methyl iodide
Conditions | Yield |
---|---|
Stage #1: 1-bromo-2-(triisopropylsilyl)acetylene; 3,4,5-trifluorobenzoic acid With [Ru(O2CMes)2(p-cymene)] In 1,4-dioxane at 120℃; for 16h; Inert atmosphere; Schlenk technique; Stage #2: methyl iodide With potassium carbonate In 1,4-dioxane; acetonitrile at 50℃; for 2h; Inert atmosphere; Schlenk technique; | 84% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; | 80.1% |
1-(diphenylmethyl)-3-hydroxyazetidine
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 50℃; for 19h; | 79% |
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 2h; Inert atmosphere; | 76% |
triphenylbismuthane
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
With H2O2 In diethyl ether byproducts: H2O; 3,4,5-trifluorobenzoic acid + 37% H2O2 added to soln. of Ph3Bi (2:1:1); kept (12 h, 20°C); crystals filtered off; dried; | 74% |
3,4,5-trifluorobenzoic acid
3,4,5-trifluoro-2-nitrobenzoic acid
Conditions | Yield |
---|---|
With sulfuric acid; nitric acid at 90℃; for 1h; oil bath; | 73% |
3,4,5-trifluorobenzoic acid
Conditions | Yield |
---|---|
Stage #1: 3,4,5-trifluorobenzoic acid With n-butyllithium In tetrahydrofuran; hexane at -78 - 0℃; for 3h; Inert atmosphere; Stage #2: With iodine In tetrahydrofuran; hexane at -78 - 25℃; Inert atmosphere; Stage #3: With hydrogenchloride In water | 72% |
Stage #1: 3,4,5-trifluorobenzoic acid With n-butyllithium In tetrahydrofuran at -78℃; for 2.5h; Stage #2: With iodine In tetrahydrofuran at -78℃; for 0.5h; | 65.6% |
3,4,5-trifluorobenzoic acid
1-(2.3.4-Trimethoxybenzoyl)piperazin
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 4h; | 70% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View