Products

Refine

Country

Business Type

Certificate

Display

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

6-chlorobenzo[b][1,4]benzothiazepine CAS NO.13745-86-3

Cas:13745-86-3

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. As a leading manufacturer and supplier of chemicals in China, Day

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

11-Chloro-dibenzo[b,f][1,4]thiazepine CAS 13745-86-3

Cas:13745-86-3

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 13745-86-3 with best quality

Cas:13745-86-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Quetiapine Impurity F (11-Chlorodibenzo[b,f][1,4]thiazepine)

Cas:13745-86-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

11-Chloro-dibenzo[b,f][1,4]thiazepine CAS:13745-86-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qua

11-Chloro-dibenzo[b,f][1,4]thiazepine CAS:13745-86-3

Cas:13745-86-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists

11-Chloro-dibenzo[b,f][ 1,4]thiazepine 13745-86-3

Cas:13745-86-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

11-Chlorodibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Gram

FOB Price: $649.19

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

11-Chloro-dibenzo[b,f][1,4]thiazepine/High quality/Best price

Cas:13745-86-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

6-chlorobenzo[b][1,4]benzothiazepine

Cas:13745-86-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Pale-Yellow Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:A metabolite o

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity 11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 11-Chloro-dibenzo[b,f][1,4]thiazepine CAS: 13745-86-3 MF: C13H8ClNS MW: 245.73 EINECS: Mol File: 13745-86-3.mol 11-Chloro-dibenzo[b,f][1,4]thiazepine Structure 11-Chloro-dibenzo[b,f][1,4]thiazepine Chemical Properti

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Quetiapine Impurity F (11-Chlorodibenzo[b,f][1,4]thiazepine)

Cas:13745-86-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Quetiapine Impurity F (11-Chlorodibenzo[b,f][1,4]thiazepine)

Cas:13745-86-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Quetiapine Impurity F (11-Chlorodibenzo[b,f][1,4]thiazepine)

Cas:13745-86-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Quetiapine Impurity F (11-Chlorodibenzo[b,f][1,4]thiazepine)

Cas:13745-86-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Dibenzo[b,f][1,4]thiazepine,11-chloro-

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

11-Chloro-dibenzo[b,f][1,4]thiazepine

Cas:13745-86-3

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

dibenzo[b,f][1,4]thiazepin-11-one
3159-07-7

dibenzo[b,f][1,4]thiazepin-11-one

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With trichlorophosphate In toluene at 100℃; for 12h; Inert atmosphere;99%
With N,N-dimethyl-aniline; trichlorophosphate at 106℃; for 6h; Heating / reflux;97%
With N,N-dimethyl-aniline; trichlorophosphate at 106℃; for 6h; Heating / reflux;97%
2-((2-aminophenyl)thio)benzoic acid
54920-98-8

2-((2-aminophenyl)thio)benzoic acid

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With trichlorophosphate for 5 - 6h; Product distribution / selectivity; Heating / reflux;
With triethylamine; trichlorophosphate In toluene for 5 - 6h; Product distribution / selectivity; Heating / reflux;
With trichlorophosphate In toluene for 5 - 6h; Product distribution / selectivity; Heating / reflux;
dibenzo[b,f][1,4]thiazepin-11-one
3159-07-7

dibenzo[b,f][1,4]thiazepin-11-one

dibenzo[b,f][1,4]thiazepine(10H)one

dibenzo[b,f][1,4]thiazepine(10H)one

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With phosphorus pentachloride; nitrogen In dichloromethane
With phosphorus pentachloride; nitrogen In dichloromethane; toluene
phenyl [2-(phenylsulphanyl)phenyl]carbamate
111974-73-3

phenyl [2-(phenylsulphanyl)phenyl]carbamate

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: polyphosphoric acid / Heating
2: N,N-dimethyl-aniline; trichlorophosphate / 105 °C
View Scheme
Multi-step reaction with 2 steps
1: PPA / 100 °C
2: trichlorophosphate / N,N-dimethyl-aniline; dichloromethane
View Scheme
Multi-step reaction with 2 steps
1: polyphosphoric acid / 8 h / 100 - 105 °C
2: N,N-dimethyl-aniline; trichlorophosphate / toluene
View Scheme
Multi-step reaction with 2 steps
1: methanesulfonic acid; phosphorus pentoxide / 2.5 h / 80 - 110 °C
2: trichlorophosphate; N,N-dimethyl-aniline / 3 h / 120 °C
View Scheme
2-nitrophenyl phenyl sulfide
4171-83-9

2-nitrophenyl phenyl sulfide

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogen / methanol / 4137.29 Torr
2: sodium carbonate
3: polyphosphoric acid / Heating
4: N,N-dimethyl-aniline; trichlorophosphate / 105 °C
View Scheme
Multi-step reaction with 4 steps
1: hydrogen / methanol / 4137.29 Torr
2: sodium carbonate / tetrahydrofuran; water
3: PPA / 100 °C
4: trichlorophosphate / N,N-dimethyl-aniline; dichloromethane
View Scheme
Multi-step reaction with 4 steps
1: iron; ammonium chloride / water
2: sodium carbonate / toluene
3: polyphosphoric acid / 8 h / 100 - 105 °C
4: N,N-dimethyl-aniline; trichlorophosphate / toluene
View Scheme
2-phenylsulfanyl-aniline
1134-94-7

2-phenylsulfanyl-aniline

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium carbonate
2: polyphosphoric acid / Heating
3: N,N-dimethyl-aniline; trichlorophosphate / 105 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium carbonate / tetrahydrofuran; water
2: PPA / 100 °C
3: trichlorophosphate / N,N-dimethyl-aniline; dichloromethane
View Scheme
Multi-step reaction with 3 steps
1: sodium carbonate / toluene
2: polyphosphoric acid / 8 h / 100 - 105 °C
3: N,N-dimethyl-aniline; trichlorophosphate / toluene
View Scheme
Multi-step reaction with 3 steps
1.1: toluene / 0.08 h / 4 °C
1.2: 1.5 h / 4 °C
2.1: methanesulfonic acid; phosphorus pentoxide / 2.5 h / 80 - 110 °C
3.1: trichlorophosphate; N,N-dimethyl-aniline / 3 h / 120 °C
View Scheme
thiophenol
108-98-5

thiophenol

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: sodium hydroxide / dimethyl sulfoxide / 80 °C
2: hydrogen / methanol / 4137.29 Torr
3: sodium carbonate / tetrahydrofuran; water
4: PPA / 100 °C
5: trichlorophosphate / N,N-dimethyl-aniline; dichloromethane
View Scheme
Multi-step reaction with 5 steps
1: copper; sodium hydroxide / tetralin / 6 h / 130 °C
2: sulfuric acid / toluene / 1 h / 0 - 80 °C
3: hydroxylamine hydrochloride / ethanol / 3 h / Reflux
4: toluene-4-sulfonic acid / toluene / Reflux
5: trichlorophosphate / 4 h / Reflux
View Scheme
Multi-step reaction with 5 steps
1: sodium hydroxide / methanol
2: iron; ammonium chloride / water
3: sodium carbonate / toluene
4: polyphosphoric acid / 8 h / 100 - 105 °C
5: N,N-dimethyl-aniline; trichlorophosphate / toluene
View Scheme
2-Chloronitrobenzene
88-73-3

2-Chloronitrobenzene

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: sodium hydroxide / dimethyl sulfoxide / 80 °C
2: hydrogen / methanol / 4137.29 Torr
3: sodium carbonate / tetrahydrofuran; water
4: PPA / 100 °C
5: trichlorophosphate / N,N-dimethyl-aniline; dichloromethane
View Scheme
Multi-step reaction with 5 steps
1: sodium hydroxide / methanol
2: iron; ammonium chloride / water
3: sodium carbonate / toluene
4: polyphosphoric acid / 8 h / 100 - 105 °C
5: N,N-dimethyl-aniline; trichlorophosphate / toluene
View Scheme
Thiosalicylic acid
147-93-3

Thiosalicylic acid

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium hydroxide / water; isopropyl alcohol
2: ethyl acetate
3: triethylamine; benzotriazol-1-ol / dichloromethane
4: trichlorophosphate
View Scheme
Multi-step reaction with 4 steps
1: potassium hydroxide / water; isopropyl alcohol / 20 °C
2: hydrogen; palladium on activated charcoal / ethyl acetate / 20 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; triethylamine / dichloromethane / 12 h / 20 °C
4: trichlorophosphate / 2 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: potassium hydroxide / isopropyl alcohol; water / 20 °C
2: hydrogen; palladium on activated charcoal / ethyl acetate / 20 °C
3: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 12 h / 20 °C
4: trichlorophosphate / 2 h / Reflux
View Scheme
ortho-nitrofluorobenzene
1493-27-2

ortho-nitrofluorobenzene

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium hydroxide / water; isopropyl alcohol
2: ethyl acetate
3: triethylamine; benzotriazol-1-ol / dichloromethane
4: trichlorophosphate
View Scheme
Multi-step reaction with 4 steps
1: potassium hydroxide / water; isopropyl alcohol / 20 °C
2: hydrogen; palladium on activated charcoal / ethyl acetate / 20 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; triethylamine / dichloromethane / 12 h / 20 °C
4: trichlorophosphate / 2 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: potassium hydroxide / isopropyl alcohol; water / 20 °C
2: hydrogen; palladium on activated charcoal / ethyl acetate / 20 °C
3: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 12 h / 20 °C
4: trichlorophosphate / 2 h / Reflux
View Scheme
2‑(2‑nitrophenylsulfanyl)benzoic acid
19806-43-0

2‑(2‑nitrophenylsulfanyl)benzoic acid

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ethyl acetate
2: triethylamine; benzotriazol-1-ol / dichloromethane
3: trichlorophosphate
View Scheme
Multi-step reaction with 3 steps
1: hydrogen; palladium on activated charcoal / ethyl acetate / 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; triethylamine / dichloromethane / 12 h / 20 °C
3: trichlorophosphate / 2 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: hydrogen; palladium on activated charcoal / ethyl acetate / 20 °C
2: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 12 h / 20 °C
3: trichlorophosphate / 2 h / Reflux
View Scheme
2-(phenylthio)benzoic acid
1527-12-4

2-(phenylthio)benzoic acid

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sulfuric acid / toluene / 1 h / 0 - 80 °C
2: hydroxylamine hydrochloride / ethanol / 3 h / Reflux
3: toluene-4-sulfonic acid / toluene / Reflux
4: trichlorophosphate / 4 h / Reflux
View Scheme
thio-xanthene-9-one
492-22-8

thio-xanthene-9-one

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydroxylamine hydrochloride / ethanol / 3 h / Reflux
2: toluene-4-sulfonic acid / toluene / Reflux
3: trichlorophosphate / 4 h / Reflux
View Scheme
9H-thioxanthen-9-one oxime
20169-45-3

9H-thioxanthen-9-one oxime

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / toluene / Reflux
2: trichlorophosphate / 4 h / Reflux
View Scheme
ortho-chlorobenzoic acid
118-91-2

ortho-chlorobenzoic acid

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: copper; sodium hydroxide / tetralin / 6 h / 130 °C
2: sulfuric acid / toluene / 1 h / 0 - 80 °C
3: hydroxylamine hydrochloride / ethanol / 3 h / Reflux
4: toluene-4-sulfonic acid / toluene / Reflux
5: trichlorophosphate / 4 h / Reflux
View Scheme
2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium carbonate; iron; copper / N,N-dimethyl-formamide / 3 h / 120 °C
2.1: toluene / 0.08 h / 4 °C
2.2: 1.5 h / 4 °C
3.1: methanesulfonic acid; phosphorus pentoxide / 2.5 h / 80 - 110 °C
4.1: trichlorophosphate; N,N-dimethyl-aniline / 3 h / 120 °C
View Scheme
iodobenzene
591-50-4

iodobenzene

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium carbonate; iron; copper / N,N-dimethyl-formamide / 3 h / 120 °C
2.1: toluene / 0.08 h / 4 °C
2.2: 1.5 h / 4 °C
3.1: methanesulfonic acid; phosphorus pentoxide / 2.5 h / 80 - 110 °C
4.1: trichlorophosphate; N,N-dimethyl-aniline / 3 h / 120 °C
View Scheme
dibenzo[b,f][1,4]thiazepin-11-ol

dibenzo[b,f][1,4]thiazepin-11-ol

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With trichlorophosphate at 70℃; for 3h;
1-[2-(2-hydroxyethoxy)ethyl]piperazine
13349-82-1

1-[2-(2-hydroxyethoxy)ethyl]piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Quetiapine
111974-69-7

Quetiapine

Conditions
ConditionsYield
In toluene at 105 - 107℃;99%
In toluene at 110 - 120℃; for 8h; Product distribution / selectivity;98%
In toluene Reflux;92%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

(2-(piperazin-1-yl)ethoxy)methanol

(2-(piperazin-1-yl)ethoxy)methanol

Quetiapine
111974-69-7

Quetiapine

Conditions
ConditionsYield
With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; 4-phenyl-N-methylpyridinium iodide; 4,4'-di-tert-butyl-2,2'-bipyridine; zinc In dimethyl sulfoxide at 80℃; for 8h; Reagent/catalyst; Inert atmosphere;99%
4-ethylpiperazine
5308-25-8

4-ethylpiperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-[4-ethyl-1-piperazinyl]dibenzo[b,f][1,4]thiazepine
1011758-03-4

11-[4-ethyl-1-piperazinyl]dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium carbonate In toluene for 5h;96%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

butyl magnesium bromide
693-04-9

butyl magnesium bromide

11-butyl-dibenzo[b,f][1,4]thiazepine

11-butyl-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
iron(III)-acetylacetonate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; diethyl ether at -78 - 20℃; for 0.0833333h; Product distribution / selectivity;93%
iron(III)-acetylacetonate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20℃; for 0.0833333h; Product distribution / selectivity;93%
pyrrolidine
123-75-1

pyrrolidine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-(pyrrolidin-1-yl)dibenzo[b,f][1,4]thiazepine
1345730-54-2

11-(pyrrolidin-1-yl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With triethylamine In toluene at 100℃; for 6h;92%
1H-imidazole
288-32-4

1H-imidazole

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-(imidazol-1-yl)dibenzo[b,f][1,4]thiazepine
1345730-51-9

11-(imidazol-1-yl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With triethylamine In toluene at 100℃; for 7h;92%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

4-Aminoacetophenone
99-92-3

4-Aminoacetophenone

1-(4-(dibenzo[b,f][1,4]thiazepin-11-ylamino)phenyl)ethanone

1-(4-(dibenzo[b,f][1,4]thiazepin-11-ylamino)phenyl)ethanone

Conditions
ConditionsYield
With pyridine for 4h; Heating;91%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

cyclohexylmagnesiumchloride
931-51-1

cyclohexylmagnesiumchloride

11-cyclohexyl-dibenzo[b,f][1,4]thiazepine

11-cyclohexyl-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
iron(III)-acetylacetonate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; diethyl ether at -78 - 20℃; for 0.0833333h; Product distribution / selectivity;89%
iron(III)-acetylacetonate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20℃; for 0.0833333h; Product distribution / selectivity;89%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

1,2,4-Triazole
288-88-0

1,2,4-Triazole

11-(1,2,4-triazol-1-yl)dibenzo[b,f][1,4]thiazepine
1345730-55-3

11-(1,2,4-triazol-1-yl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With triethylamine In toluene at 100℃; for 6h;89%
piperazine
110-85-0

piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-(1-piperazinyl)dibenzo[b,f][1,4]thiazepine
5747-48-8

11-(1-piperazinyl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With hydrogenchloride In ethanol; toluene88%
With hydrogenchloride In ethanol; toluene88%
With hydrogenchloride In ethanol; toluene88%
piperazine
110-85-0

piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-[4-(2-hydroxyethyl)-1-piperazinyl]dibenzo[b,f][1,4]thiazepine
945668-94-0

11-[4-(2-hydroxyethyl)-1-piperazinyl]dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In 5,5-dimethyl-1,3-cyclohexadiene at 105 - 115℃; for 5h; Reagent/catalyst;88%
In toluene for 4h; Heating;
piperazine
110-85-0

piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride
753475-15-9

11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In isopropyl alcohol; toluene88%
2-methylimidazole
693-98-1

2-methylimidazole

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-(2-methylimidazol-1-yl)dibenzo[b,f][1,4]thiazepine
1345730-52-0

11-(2-methylimidazol-1-yl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With triethylamine In toluene at 100℃; for 8h;88%
piperazine
110-85-0

piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

N-Dealkyl Quetiapine dihydrochloride

N-Dealkyl Quetiapine dihydrochloride

Conditions
ConditionsYield
With IPA-HCl In toluene87%
In toluene
In dimethyl sulfoxide; toluene at 25 - 30℃; for 3h; Product distribution / selectivity; Industry scale; Inert atmosphere;
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

(1,3-dioxan-2-yl)ethylmagnesium bromide

(1,3-dioxan-2-yl)ethylmagnesium bromide

11-(2-[1,3]dioxane-2-yl-ethyl)-dibenzo[b,f][1,4]thiazepine

11-(2-[1,3]dioxane-2-yl-ethyl)-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
iron(III)-acetylacetonate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; diethyl ether at -78 - 20℃; for 0.0833333h; Product distribution / selectivity;86%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

1,3-dioxane-2-yl-ethyl magnesium chloride

1,3-dioxane-2-yl-ethyl magnesium chloride

11-(2-[1,3]dioxane-2-yl-ethyl)-dibenzo[b,f][1,4]thiazepine

11-(2-[1,3]dioxane-2-yl-ethyl)-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
iron(III)-acetylacetonate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20℃; for 0.0833333h; Product distribution / selectivity;86%
(2-hydroxyethyl)(methyl)amine
109-83-1

(2-hydroxyethyl)(methyl)amine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

C16H16N2OS

C16H16N2OS

Conditions
ConditionsYield
With triethylamine In toluene at 60 - 65℃; for 8h;83%
4-methyl-1H-imidazole
822-36-6

4-methyl-1H-imidazole

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-(4-methylimidazol-1-yl)dibenzo[b,f][1,4]thiazepine
1345730-53-1

11-(4-methylimidazol-1-yl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With triethylamine In toluene at 100℃; for 8h;80%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

Cyclopropylamine
765-30-0

Cyclopropylamine

11-(cyclopropylamino)dibenzo[b,f][1,4]thiazepine hydrochloride

11-(cyclopropylamino)dibenzo[b,f][1,4]thiazepine hydrochloride

Conditions
ConditionsYield
Stage #1: 11-chloro-dibenzo[b,f][1,4]thiazepine; Cyclopropylamine With triethylamine In water; toluene at 60 - 70℃; for 6h;
Stage #2: With hydrogenchloride In hexane
79%
piperazine
110-85-0

piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-piperazin-1-yldibenzo[b,f][1,4]thiazepine
1159882-47-9

11-piperazin-1-yldibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
In o-xylene at 20 - 142℃; for 40h; Heating / reflux;78%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

benzylamine
100-46-9

benzylamine

11-(benzylamino)dibenzo[b,f][1,4]thiazepine
1345730-60-0

11-(benzylamino)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
With triethylamine at 60 - 65℃; for 4h;76%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

(R)-2-benzylpiperazine
131288-11-4

(R)-2-benzylpiperazine

11-(3-(R)-benzylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine

11-(3-(R)-benzylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
In toluene for 19h; Heating / reflux;74%
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

(E)-tert-butyl 4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazine-1-carboxylate
1217310-64-9

(E)-tert-butyl 4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
In o-xylene at 130℃; for 7h;62%
1-(2-hydroxyethyl)piperazine
103-76-4

1-(2-hydroxyethyl)piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

O-Dealkyl Quetiapine
329216-67-3

O-Dealkyl Quetiapine

Conditions
ConditionsYield
In xylene at 170℃; for 12 - 18h;53%
In xylene Heating;
In 1-methyl-pyrrolidin-2-one; toluene for 6 - 8h; Heating / reflux;
11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

7-(benzyloxy)-12-(10,11-difluoro-7,12-dihydrobenzo[e]naphtho[1,2-b]thiepin-7-yl)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

7-(benzyloxy)-12-(10,11-difluoro-7,12-dihydrobenzo[e]naphtho[1,2-b]thiepin-7-yl)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

7-(benzyloxy)-12-(dibenzo[b,f][1,4]thiazepin-11-yl)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

7-(benzyloxy)-12-(dibenzo[b,f][1,4]thiazepin-11-yl)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

Conditions
ConditionsYield
Stage #1: 7-(benzyloxy)-12-(10,11-difluoro-7,12-dihydrobenzo[e]naphtho[1,2-b]thiepin-7-yl)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione With potassium carbonate In dimethyl sulfoxide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: 11-chloro-dibenzo[b,f][1,4]thiazepine In dimethyl sulfoxide at 80℃; for 0.5h; Inert atmosphere;
46%
1-[2-(2-hydroxyethoxy)ethyl]piperazine
13349-82-1

1-[2-(2-hydroxyethoxy)ethyl]piperazine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

(2E)-but-2-enedioic acid
110-17-8

(2E)-but-2-enedioic acid

quetiapine hemi-fumarate

quetiapine hemi-fumarate

Conditions
ConditionsYield
Stage #1: 1-[2-(2-hydroxyethoxy)ethyl]piperazine; 11-chloro-dibenzo[b,f][1,4]thiazepine With triethylamine In toluene at 95℃; for 60h;
Stage #2: (2E)-but-2-enedioic acid In ethanol at 25℃; for 0.5h; Product distribution / selectivity;
40%
α-picoline
109-06-8

α-picoline

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

C19H14N2S

C19H14N2S

Conditions
ConditionsYield
Stage #1: α-picoline With n-butyllithium In tetrahydrofuran at -78 - 20℃; for 2h; Inert atmosphere;
Stage #2: 11-chloro-dibenzo[b,f][1,4]thiazepine In tetrahydrofuran at -78 - 20℃; for 12h; Inert atmosphere;
28%
piperidine
110-89-4

piperidine

11-chloro-dibenzo[b,f][1,4]thiazepine
13745-86-3

11-chloro-dibenzo[b,f][1,4]thiazepine

11-piperidin-1-yl-dibenzo[b,f][1,4]thiazepine
5814-72-2

11-piperidin-1-yl-dibenzo[b,f][1,4]thiazepine

Conditions
ConditionsYield
In xylene for 5h; Heating;
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View