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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Manufacturer 1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Hangzhou Fandachem Co.,Ltd

Hangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting 2,4-Dichlorofluorobenzene (2,4-Dichloro-1-fluorobenzene , 2,4-Dichloro Fluorobenzene) CAS:1435-48-9 from FandaChem, Please contact us by email

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

High quality 2,4-Dichlorofluorobenzene CAS NO.1435-48-9

Cas:1435-48-9

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

1,3-Dichloro-4-fluorobenzene Manufacturer/High quality/Best price/In stock

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ---------------------------------------------------------------------------------------------

High purity Various Specifications 2,4-Dichlorofluorobenzene CAS:1435-48-9

Cas:1435-48-9

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

1435-48-9 1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1,3-dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 1435-48-9 1,3-Dichloro-4-fluorobenzene Manufacturer

Cas:1435-48-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,4-Dichlorofluorobenzene

Cas:1435-48-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Competitive Price High Quality Fast Delivery custom-made Welcome to Henan Tianfu Chemical Co., Ltd. website. Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble me

1,3-Dichloro-4-fluorobenzene 1435-48-9 C6H3Cl2F

Cas:1435-48-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 1435-48-9 with best quality

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,3-Dichloro-4-fluorobenzene 1435-48-9

Cas:1435-48-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

1,3-Dichloro-4-fluorobenzene CAS:1435-48-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

1,3-Dichloro-4-fluorobenzene CAS:1435-48-9

Cas:1435-48-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $50.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1,3-Dichloro-4-Fluorobenzene

Cas:1435-48-9

Min.Order:0

Negotiable

Type:Manufacturers

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Hefei Zhaobo Technology Co., Ltd.

1,3-Dichloro-4-fluorobenzene CAS 1435-48-9 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict qual

1,3-Dichloro-4-fluorobenzene CAS 1435-48-9

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1,3-DICHLORO-4-FLUOROBENZENE

Cas:1435-48-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Miheng Trading Co., Ltd.

1,3-Dichloro-4-fluorobenzene CAS 1435-48-9 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to

1,3-Dichloro-4-fluorobenzene CAS 1435-48-9

Cas:1435-48-9

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,4-Dichlorofluorobenzene

Cas:1435-48-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Colorless Liquid Storage:sealed and stored Package:25kg/drum, or as per your request. Application:Used as a pesticide and pharmaceutical intermediates Transportation:as per your requ

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

lowest price 2,4-Dichlorofluorobenzene

Cas:1435-48-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1,3-Dichloro-4-fluorobenzene CAS: 1435-48-9 MF: C6H3Cl2F MW: 164.99 EINECS: 406-160-1 Mol File: 1435-48-9.mol 1,3-Dichloro-4-fluorobenzene Structure 1,3-Dichloro-4-fluorobenzene Chemical Properties Melting point

1,3-Dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

High quality 2,4-Dichlorofluorobenzene CAS NO.1435-48-9 CAS NO.1435-48-9

Cas:1435-48-9

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,4-Dichlorofluobenzene

Cas:1435-48-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

1,3-dichloro-4-fluorobenzene

Cas:1435-48-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,4-Dichloroaniline
554-00-7

2,4-Dichloroaniline

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Stage #1: 2,4-Dichloroaniline With hydrogenchloride; fluoroboric acid; sodium nitrite In water at 25℃; for 0.00555556h; Balz-Schiemann Reaction;
Stage #2: In 1,2-dichloro-benzene at 190℃; for 0.0166667h; Balz-Schiemann Reaction;
93%
Stage #1: 2,4-Dichloroaniline With sodium tetrafluoroborate; sodium nitrite acidic conditions;
Stage #2: at 150 - 170℃; Schieman reaction; Further stages.;
1,2,4-Trichlorobenzene
120-82-1

1,2,4-Trichlorobenzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With potassium fluoride; 5,11,17,23,29,35-hexakis(tert-butyl)-37,38,39,40,41-hexakis(hydroxy)calix[6]arene In sulfolane at 185℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere; Sealed tube;92%
3-chloro-4-fluoronitrobenzene
350-30-1

3-chloro-4-fluoronitrobenzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With chlorine at 170 - 180℃; for 8h; Temperature;91.7%
Multi-step reaction with 2 steps
1: titanium (III)-chloride; water
2: aqueous HCl / Diazotization.Erwaermen der Diazoniumsalz-Loesung mit CuCl
View Scheme
2,4-dichloroaniline hydrochloride
29084-76-2

2,4-dichloroaniline hydrochloride

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Stage #1: 2,4-dichloroaniline hydrochloride With hydrogenchloride at -5℃;
Stage #2: With tetrafluoroboric acid; sodium nitrite In water at 0℃; for 0.0833333h;
50.1%
3-chloro-4-fluorophenylamine
367-21-5

3-chloro-4-fluorophenylamine

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With hydrogenchloride Diazotization.Erwaermen der Diazoniumsalz-Loesung mit CuCl;
2,4-Dinitrofluorobenzene
70-34-8

2,4-Dinitrofluorobenzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With chlorine at 200℃;
2,3-dichlorofluorobenzene
36556-50-0

2,3-dichlorofluorobenzene

A

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

B

3-chlorofluorobenzene
625-98-9

3-chlorofluorobenzene

C

1,4-dichloro-2-fluorobenzene
348-59-4

1,4-dichloro-2-fluorobenzene

D

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
In acetonitrile for 10h; Product distribution; Irradiation;A 5 % Chromat.
B 5 % Chromat.
C 13 % Chromat.
D 1 % Chromat.
2,4-dichlorophenylboronic acid
68716-47-2

2,4-dichlorophenylboronic acid

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With cesium fluoroxysulphate In methanol at -10℃; for 24h;28 % Spectr.
(N-B)-Perhydro-2-(2,4-dichlorophenyl)-6-methyl-1,3-dioxa-6-aza-2-boracine

(N-B)-Perhydro-2-(2,4-dichlorophenyl)-6-methyl-1,3-dioxa-6-aza-2-boracine

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With meta-dinitrobenzene; cesium fluoroxysulphate In acetonitrile Ambient temperature;40 % Spectr.
fluorobenzene
462-06-6

fluorobenzene

iron-powder

iron-powder

A

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

B

1-Chloro-4-fluorobenzene
352-33-0

1-Chloro-4-fluorobenzene

C

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Einleiten von 2 Mol Chlor;
2.4-dichloro-benzodiazonium-(1)-tetrafluoroborate

2.4-dichloro-benzodiazonium-(1)-tetrafluoroborate

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Thermolysis;
4-Fluoronitrobenzene
350-46-9

4-Fluoronitrobenzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: iron-powder / Einleiten von Chlor
2: titanium (III)-chloride; water
3: aqueous HCl / Diazotization.Erwaermen der Diazoniumsalz-Loesung mit CuCl
View Scheme
1,2-dichloro-benzene
95-50-1

1,2-dichloro-benzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: nitric acid; sulfuric acid / 2 h / 95 - 100 °C
2.1: potassium fluoride / 3 h / 140 - 150 °C
2.2: 7 h / 165 - 170 °C
3.1: chlorine / 8 h / 170 - 180 °C
View Scheme
3,4-dichloronitrobenzene
99-54-7

3,4-dichloronitrobenzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium fluoride / 3 h / 140 - 150 °C
1.2: 7 h / 165 - 170 °C
2.1: chlorine / 8 h / 170 - 180 °C
View Scheme
C13H4Cl4F2O

C13H4Cl4F2O

A

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

B

C7H2Cl2FO2(1-)*Na(1+)

C7H2Cl2FO2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: C13H4Cl4F2O With sodium hydroxide at 90 - 100℃; for 1h;
Stage #2: In 1,4-dioxane at 110 - 150℃; for 3h;
C13H4Cl4F2O

C13H4Cl4F2O

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
With sodium hydroxide at 140 - 150℃; Temperature;
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-5-fluoronitrobenzene
2105-59-1

2,4-dichloro-5-fluoronitrobenzene

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 50℃; for 2h; Temperature;99.3%
With sulfuric acid; nitric acid at 50 - 60℃; for 3h;98%
With sulfuric acid; potassium nitrate at 0 - 20℃; for 12h;97%
With sulfuric acid; nitric acid
With sulfuric acid; sulfur trioxide; nitric acid
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,6-dichloro-3-fluorobenzenethiol

2,6-dichloro-3-fluorobenzenethiol

Conditions
ConditionsYield
Stage #1: 1,3-dichloro-4-fluorobenzene With n-butyllithium In tetrahydrofuran at -78℃; for 1.5h; Inert atmosphere;
Stage #2: With sulfur In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;
99%
carbon dioxide
124-38-9

carbon dioxide

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-5-fluorobenzoyl chloride
86393-34-2

2,4-dichloro-5-fluorobenzoyl chloride

Conditions
ConditionsYield
With Cationic resin catalyst In tetrachloromethane at 40 - 60℃; under 15001.5 Torr; for 5h; Pressure; Temperature; Reagent/catalyst;98.8%
tetrachloromethane
56-23-5

tetrachloromethane

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

1,5-dichloro-2-fluoro-4-(trichloromethyl)benzene

1,5-dichloro-2-fluoro-4-(trichloromethyl)benzene

Conditions
ConditionsYield
With aluminum (III) chloride at 40℃; for 4h; Temperature;95.2%
With phosphotungstic acid supported on magnetic ZrO2 for 0.5h; Autoclave; Reflux;94%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

2-(3,5-dichloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-(3,5-dichloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions
ConditionsYield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 80℃; for 6h; Inert atmosphere;94%
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 80℃; for 18h; Inert atmosphere;
With (1,5-cyclooctadiene)(methoxy)iridium(l) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 80℃; for 24h; Inert atmosphere;
methanol
67-56-1

methanol

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

1,3-dichloro-4-methoxybenzene
553-82-2

1,3-dichloro-4-methoxybenzene

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 2,2,2-trifluoroethanol; 1,2-dichloro-ethane at 40℃; for 48h; Reagent/catalyst; Solvent; Irradiation;94%
4-(3-((4-chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
320366-66-3

4-(3-((4-chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

gefitinib
184475-35-2

gefitinib

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide Reflux;91%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

acetyl chloride
75-36-5

acetyl chloride

2,4-dichloro-5-fluoroacetophenone
704-10-9

2,4-dichloro-5-fluoroacetophenone

Conditions
ConditionsYield
With aluminum (III) chloride at 110℃; Reagent/catalyst; Temperature;89.3%
With aluminum (III) chloride Friedel Crafts acylation;52%
With aluminum (III) chloride at 30 - 120℃; Product distribution / selectivity;
aluminum (III) chloride
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

isopropyl alcohol
67-63-0

isopropyl alcohol

2,4-dichloro-1-isopropoxybenzene
6851-40-7

2,4-dichloro-1-isopropoxybenzene

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 2,2,2-trifluoroethanol; 1,2-dichloro-ethane at 40℃; for 48h; Irradiation;89%
ethanol
64-17-5

ethanol

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-1-ethoxybenzene
5392-86-9

2,4-dichloro-1-ethoxybenzene

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 2,2,2-trifluoroethanol; 1,2-dichloro-ethane at 40℃; for 48h; Irradiation;87%
Cyclopropylmethanol
2516-33-8

Cyclopropylmethanol

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-1-(cyclopropylmethoxy)benzene

2,4-dichloro-1-(cyclopropylmethoxy)benzene

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 2,2,2-trifluoroethanol; 1,2-dichloro-ethane at 40℃; for 48h; Irradiation;87%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

5’-chloro-2’-fluoro-[1,1’-biphenyl]-2-carbonitrile

5’-chloro-2’-fluoro-[1,1’-biphenyl]-2-carbonitrile

Conditions
ConditionsYield
With potassium pivalate; palladium dichloride In N,N-dimethyl acetamide at 150℃; for 16h; regioselective reaction;86%
tetrachloromethane
56-23-5

tetrachloromethane

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-5-fluorobenzoyl chloride
86393-34-2

2,4-dichloro-5-fluorobenzoyl chloride

Conditions
ConditionsYield
Stage #1: tetrachloromethane; 1,3-dichloro-4-fluorobenzene for 0.5h; Autoclave; Reflux;
Stage #2: With water at 20 - 40℃; for 1h; Reagent/catalyst;
86%
Methyl formate
107-31-3

Methyl formate

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,6-dichloro-3-fluorobenzaldehyde

2,6-dichloro-3-fluorobenzaldehyde

Conditions
ConditionsYield
Stage #1: 1,3-dichloro-4-fluorobenzene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: Methyl formate In tetrahydrofuran at 10 - 15℃; for 16h; Inert atmosphere;
85.49%
Stage #1: 1,3-dichloro-4-fluorobenzene With n-butyllithium In tetrahydrofuran; hexanes at -78 - -70℃; for 2h; Inert atmosphere;
Stage #2: Methyl formate In tetrahydrofuran; hexanes at -78℃; Inert atmosphere;
Stage #3: With water; ammonium chloride In tetrahydrofuran; hexanes at 20℃; Inert atmosphere;
Stage #1: 1,3-dichloro-4-fluorobenzene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1.5h; Inert atmosphere;
Stage #2: Methyl formate In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water
3,5-dimethoxyphenol
500-99-2

3,5-dimethoxyphenol

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-1-(3,5-dimethoxyphenoxy)benzene
1379803-44-7

2,4-dichloro-1-(3,5-dimethoxyphenoxy)benzene

Conditions
ConditionsYield
Stage #1: 3,5-dimethoxyphenol With caesium carbonate In 1-methyl-pyrrolidin-2-one at 50℃; for 0.5h; Inert atmosphere;
Stage #2: 1,3-dichloro-4-fluorobenzene In 1-methyl-pyrrolidin-2-one at 120℃; for 2h; Inert atmosphere;
84%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

1-(Trimethylsilyl)imidazole
18156-74-6

1-(Trimethylsilyl)imidazole

A

trimethylsilyl fluoride
420-56-4

trimethylsilyl fluoride

B

1-(2,4-dichlorophenyl)-1H-imidazole
190199-40-7

1-(2,4-dichlorophenyl)-1H-imidazole

Conditions
ConditionsYield
With cesium fluoride In N,N-dimethyl-formamide at 60℃; for 20h; Inert atmosphere;A n/a
B 80%
ethyl acetohydroximate
10576-12-2

ethyl acetohydroximate

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

N-(2,4-Dichloro-phenoxy)-acetimidic acid ethyl ester

N-(2,4-Dichloro-phenoxy)-acetimidic acid ethyl ester

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide 1.) r.t., 30 min, 2.) 80 deg C, 1.5 h;77.8%
tetrachloromethane
56-23-5

tetrachloromethane

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

A

1,5-dichloro-2-fluoro-4-(trichloromethyl)benzene

1,5-dichloro-2-fluoro-4-(trichloromethyl)benzene

B

dichloro-bis(2,4-dichloro-5-fluorophenyl)methane

dichloro-bis(2,4-dichloro-5-fluorophenyl)methane

Conditions
ConditionsYield
at 40℃; for 2h; Temperature;A 76.6%
B 22.6%
With iron(III) chloride at 70℃; for 2h;A 75.1%
B 20.3%
With aluminum (III) chloride at 40℃; for 8h;A 3.2 g
B 13.5 g
With aluminum (III) chloride at 40℃; for 8h;
oxirane
75-21-8

oxirane

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2-(2,6-dichloro-3-fluorophenyl)ethanol

2-(2,6-dichloro-3-fluorophenyl)ethanol

Conditions
ConditionsYield
Stage #1: 1,3-dichloro-4-fluorobenzene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: oxirane In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;
75%
Stage #1: 1,3-dichloro-4-fluorobenzene With n-butyllithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: oxirane In tetrahydrofuran at -78℃; for 2h;
75%
3-bromoquinoline
5332-24-1

3-bromoquinoline

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

A

3-(3,5-dichloro-2-fluorophenyl)quinoline

3-(3,5-dichloro-2-fluorophenyl)quinoline

B

C15H8Cl2FN

C15H8Cl2FN

C

C15H8Cl2FN

C15H8Cl2FN

Conditions
ConditionsYield
With potassium pivalate; palladium dichloride In N,N-dimethyl acetamide at 150℃; for 16h; regioselective reaction;A 72%
B n/a
C n/a
(R)-4-(benzyl-methyl-amino)-1-tert-butoxy-butan-2-ol
865864-47-7

(R)-4-(benzyl-methyl-amino)-1-tert-butoxy-butan-2-ol

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

(R)-benzyl-[4-tert-butoxy-3-(2,4-dichloro-phenoxy)-butyl]-methyl amine
865865-21-0

(R)-benzyl-[4-tert-butoxy-3-(2,4-dichloro-phenoxy)-butyl]-methyl amine

Conditions
ConditionsYield
Stage #1: (R)-4-(benzyl-methyl-amino)-1-tert-butoxy-butan-2-ol With sodium hydride In dimethyl sulfoxide for 0.5h;
Stage #2: 1,3-dichloro-4-fluorobenzene In dimethyl sulfoxide
71%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

1-(Trimethylsilyl)imidazole
18156-74-6

1-(Trimethylsilyl)imidazole

1-(2,4-dichlorophenyl)-1H-imidazole
190199-40-7

1-(2,4-dichlorophenyl)-1H-imidazole

Conditions
ConditionsYield
With copper(l) iodide In methanol; N,N-dimethyl-formamide at 100℃; Inert atmosphere;70%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

2,4-dichloro-5-fluoro-benzoic acid
86522-89-6

2,4-dichloro-5-fluoro-benzoic acid

Conditions
ConditionsYield
66%
Multi-step reaction with 3 steps
1: 2 h / 40 °C
2: iron(III) chloride; water / 90 °C
3: potassium perchlorate / N,N-dimethyl-formamide / Reflux
View Scheme
4-bromobenzenecarbonitrile
623-00-7

4-bromobenzenecarbonitrile

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

A

C13H6Cl2FN

C13H6Cl2FN

B

C13H6Cl2FN

C13H6Cl2FN

C

3’,5’-dichloro-2’-fluoro-[1,1’-biphenyl]-4-carbonitrile

3’,5’-dichloro-2’-fluoro-[1,1’-biphenyl]-4-carbonitrile

Conditions
ConditionsYield
With potassium pivalate; palladium dichloride In N,N-dimethyl acetamide at 150℃; for 16h; regioselective reaction;A n/a
B n/a
C 66%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

A

C13H7Cl2FO

C13H7Cl2FO

B

C13H7Cl2FO

C13H7Cl2FO

C

3’,5’-dichloro-2’-fluoro-[1,1’-biphenyl]-4-carbaldehyde

3’,5’-dichloro-2’-fluoro-[1,1’-biphenyl]-4-carbaldehyde

Conditions
ConditionsYield
With potassium pivalate; palladium dichloride In N,N-dimethyl acetamide at 150℃; for 16h; regioselective reaction;A n/a
B n/a
C 66%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

cyclohexanol
108-93-0

cyclohexanol

2,4-dichloro-1-(cyclohexyloxy)benzene

2,4-dichloro-1-(cyclohexyloxy)benzene

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 2,2,2-trifluoroethanol; 1,2-dichloro-ethane at 40℃; for 48h; Irradiation;64%
1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

C6H2Cl3FO2S

C6H2Cl3FO2S

Conditions
ConditionsYield
With chlorosulfonic acid at 100℃; for 12h;63%
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