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Baicao Pharmaceutical Co., Ltd.

High Quality Food Grade Natural Menthol Crystals Product Name Menthol crystal Appearance Colorless acicular crystal Odor with a characteristic mint aroma

High Quality Food Grade Natural Menthol Crystals

Cas:2216-51-5

Min.Order:25 Kilogram

Negotiable

Type:Other

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Specif

L-Menthol Crystals CAS NO.2216-51-5

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

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Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

High quality Good quality L-Menthol cas NO.: 2216-51-5

Cas:2216-51-5

Min.Order:0

Negotiable

Type:Other

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways focus on: -Pharmaceutical raw materials -Chemical raw materials -Food additives -Flavors and fragrances -Feed additives -Plant extracts -Veterinary raw materials We could supply you: -Best quality -Competitive price -Perfect ser

L-menthol CAS NO.2216-51-5

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

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Leader Biochemical Group

PRODUCT DETAILS L-Men

China Biggest Factory manufacturer supply L-Menthol

Cas:2216-51-5

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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DALIAN BAIJIA IMPORT AND EXPORT CO., LTD

Dalian baijia import and export co., LTD., formerly known as xinyusheng chemical (Hong Kong) co., LTD., was founded in 2008. Its main business is fine chemical products and food additives. The company's main customers are distributed in Europe

Buy high quality of D-menthol

Cas:2216-51-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Colorless transparent needle like crystal complies Aroma

High purity L-Menthol with high quality and best price cas:2216-51-5

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $44.0 / 80.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality L-Menthol supplier in China

Cas:2216-51-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Colorless transparent needle crystals Storage:-20°C Package:2

Natural menthol crystals CAS 2216-51-5 of USP/BP/CP standard

Cas:2216-51-5

Min.Order:25 Kilogram

FOB Price: $33.0 / 40.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply L-menthol

Cas:2216-51-5

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Cyclohexanol,5-methyl-2-(1-methylethyl)-, (1R,2S,5R)- 2216-51-5 ISO Producer

Cas:2216-51-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

L-Menthol

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality L-Menthol

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

L-Menthol Manufacturer in China

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $5.0 / 6.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

High purity Cyclohexanol,5-methyl-2-(1-methylethyl)-, (1R,2S,5R)- in stock /Best price 2216-51-5

Cas:2216-51-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

L-Menthol

Cas:2216-51-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:L-Menthol CAS NO: 2216-51-5 Grade:Medical scientific research and export Molecular formula:C10H20O Molecular weight: 156.27 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data sto

L-Menthol/ CAS:2216-51-5/ raw material/ high-quality

Cas:2216-51-5

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

2216-51-5 L-Menthol

Cas:2216-51-5

Min.Order:100 Kilogram

FOB Price: $40.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent out in 24 hours after payment.Tracking number available 2) Secure and disc

L-Menthol CAS:2216-51-5

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $2.0 / 5.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New product CAS 2216-51-5 with best price

Cas:2216-51-5

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu

2216-51-5/1-P-MENTHAN-3-OL with good price

Cas:2216-51-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Manufacturers

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:white crystal Storage:Room temperature Package:25kg/drum Application:Edible spices Transportation:Express/Sea/Air Port:Any port in china

Factory Manufacturer High Quality Natural Menthol Crystals L(-)-Menthol

Cas:2216-51-5

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:colorless, transparent hexagonal or needlelike crystals Stor

CAS 2216-51-5 High Purity Synthetic Essential Spices L-Menthol

Cas:2216-51-5

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hefei TNJ chemical industry co.,ltd

Superiority Service we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to you

Good quality L-Menthol//cas 2216-51-5

Cas:2216-51-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Cyclohexanol,5-methyl-2-(1-methylethyl)-, (1R,2S,5R)- 2216-51-5

Cas:2216-51-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Shanghai Minstar Chemical Co., Ltd

L-Menthol Basic information Product Name: L-Menthol Synonyms: (1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol;(1r,3r,4s)-(-)-mentho;(1R,3R,4S)-(-)-MENTHOL;(R)-(-)-Menthol;Emtricitabine Impurity 31;Natural Menthol Crystal;L

L-Menthol

Cas:2216-51-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

2216-51-5 L-Menthol Natural Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:colorless Storage:

2216-51-5 L-Menthol Natural

Cas:2216-51-5

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

L-Menthol Lipocyclic alcohol.

Cas:2216-51-5

Min.Order:1 Kilogram

FOB Price: $15.0 / 20.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

L-Menthol CAS:2216-51-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s

L-Menthol CAS:2216-51-5

Cas:2216-51-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

menthyl allyl carbonate
76648-56-1

menthyl allyl carbonate

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With diethylamine; palladium diacetate; trisodium tris(3-sulfophenyl)phosphine In water for 0.5h; Ambient temperature;100%
(1S,2R,4R)-(-)-2-tert-butoxy-1-isopropyl-4-methylcyclohexane
34350-47-5

(1S,2R,4R)-(-)-2-tert-butoxy-1-isopropyl-4-methylcyclohexane

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With sodium iodide; cerium(III) chloride In acetonitrile at 70℃; for 2h;100%
With cerium(III) chloride; sodium iodide In acetonitrile at 70℃; for 17h;
menthyl allyl carbonate
76648-56-1

menthyl allyl carbonate

2-propanethiol
75-33-2

2-propanethiol

A

allylisopropyl sulfide
50996-72-0

allylisopropyl sulfide

B

carbon dioxide
124-38-9

carbon dioxide

C

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With Roussin's red salt ester; tetrabutylammomium bromide; potassium hydride In tetrahydrofuran; ethanol at 40℃; for 14h;A n/a
B n/a
C 100%
(R)-Citronellal
2385-77-5

(R)-Citronellal

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With hydrogen In water at 80℃; under 7500.75 Torr; for 48h; Inert atmosphere; Autoclave;100%
With 20percent 12-tungstophosphoric acid supported on MCM-41 In dichloromethane at 20℃; for 3h; Inert atmosphere;
Multi-step reaction with 2 steps
1: 0 - 5 °C
2: Raney nickel / 10 h / 70 °C / 18751.9 Torr / Inert atmosphere
View Scheme
With hydrogen In water at 60℃; under 7500.75 Torr; for 23h; Catalytic behavior; Reagent/catalyst; Temperature; Autoclave;99 %Chromat.
Conditions
ConditionsYield
With hydrogen In toluene at 100℃; under 22502.3 Torr; for 0.25h; Catalytic behavior; Pressure; Temperature; Reagent/catalyst; Flow reactor;99.9%
With hydrogen; nickel; 4-methoxy-aniline In hexane at 80℃; under 30003 Torr; for 10h; Temperature; Pressure; Solvent; Autoclave;99.9%
With ethanol; palladium on activated charcoal; sodium hydroxide; silicon at 20℃; for 72h; Schlenk technique;94%
(2R,5S)-menthone
10458-14-7, 14073-97-3

(2R,5S)-menthone

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With iron(II) chloride tetrahydrate; lithium In tetrahydrofuran; mineral oil at 20℃; for 4h; Reagent/catalyst; Inert atmosphere; stereoselective reaction;99%
With tris(pentafluorophenyl)borate; hydrogen In diethyl ether at 70℃; under 45603.1 Torr; for 12h; Solvent; Glovebox;88%
With sulfuric acid bei der elektrolytischen Reduktion;
L-menthyl acetate
2623-23-6

L-menthyl acetate

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With [Ru(2-(methylthio)-N-[(pyridin-2-yl)methyl]ethan-1-amine)(triphenylphosphine)Cl2]; potassium tert-butylate; hydrogen In toluene at 80℃; under 30003 Torr; for 3h;99%
With ytterbium(III) triflate In isopropyl alcohol for 74h; Deacetylation; Heating;95%
With sodium hydroxide In methanol; dichloromethane at 20℃; for 0.75h; Solvent;95%
Conditions
ConditionsYield
poly(4-vinylpyridinium) p-toluenesulfonate In tetrahydrofuran; ethanol at 75℃; for 45h; Hydrolysis;98%
With trichloroisocyanuric acid In methanol at 20℃; for 4h;94%
With tris-(4-bromophenyl)aminium hexachloroantimonate In methanol at 20℃; for 2.5h;93%
4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether
548464-35-3

4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; 1,3-Dimethoxybenzene In dichloromethane at 21℃; for 0.166667h;98%
With trifluorormethanesulfonic acid; toluene-4-sulfonamide In diethyl ether95%
With silver hexafluoroantimonate; 1,2,3-trimethoxybenzene In dichloromethane at 40℃; for 2.5h;93%
(1S,2R,4R)-2-(allyloxy)-1-isopropyl-4-methylcyclohexane
40940-58-7, 144266-44-4, 67528-21-6

(1S,2R,4R)-2-(allyloxy)-1-isopropyl-4-methylcyclohexane

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With diisobutylaluminium hydride; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In diethyl ether; toluene at 0 - 20℃; for 3h;97%
Stage #1: (1S,2R,4R)-2-(allyloxy)-1-isopropyl-4-methylcyclohexane; Grubbs catalyst first generation In dichloromethane at 20℃; for 12h;
Stage #2: With hydrogenchloride
95%
With triisopropoxytitanium(IV) chloride; n-butyl magnesium bromide In tetrahydrofuran; diethyl ether; hexane for 2h; Ambient temperature;94%
tert-butyl(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)dimethylsilane
76358-81-1

tert-butyl(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)dimethylsilane

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With iodine In methanol for 4h; Ambient temperature;97%
With hafnium tetrakis(trifluoromethanesulfonate) In methanol at 20℃; for 6h;96%
With hafnium tetrakis(trifluoromethanesulfonate) In methanol at 20℃; for 6h;96%
(1S,2S,6R,7R,8R)-9-[1-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxycarbonyl)-meth-(Z)-ylidene]-4,4-dimethyl-3,5-dioxa-tricyclo[5.2.1.02,6]decane-8-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
163015-24-5

(1S,2S,6R,7R,8R)-9-[1-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxycarbonyl)-meth-(Z)-ylidene]-4,4-dimethyl-3,5-dioxa-tricyclo[5.2.1.02,6]decane-8-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

A

(-)-menthol
2216-51-5

(-)-menthol

B

2-[(1R,2R,6S,7S,9R)-9-Hydroxymethyl-4,4-dimethyl-3,5-dioxa-tricyclo[5.2.1.02,6]dec-(8E)-ylidene]-ethanol
163015-25-6

2-[(1R,2R,6S,7S,9R)-9-Hydroxymethyl-4,4-dimethyl-3,5-dioxa-tricyclo[5.2.1.02,6]dec-(8E)-ylidene]-ethanol

Conditions
ConditionsYield
With diisobutylaluminium hydride In dichloromethane at -78 - 0℃;A 96%
B 93%
2-{[(tert-butyl)dimethylsilyl]oxy}-4-methyl-1-(1-methylethyl)cyclohexane
129368-71-4

2-{[(tert-butyl)dimethylsilyl]oxy}-4-methyl-1-(1-methylethyl)cyclohexane

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With cerium (IV) sulfate tetrahydrate In methanol at 130℃; for 0.333333h; Microwave irradiation;96%
menthyl hydrogen phthalate
33744-74-0

menthyl hydrogen phthalate

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With hydroxide solution at 15℃; for 5h;96%
(1R,3R,4S)-p-menth-3-yl (R)-6,7-dichloro-2,3-dibenzofuran-2-carboxylate
118166-31-7

(1R,3R,4S)-p-menth-3-yl (R)-6,7-dichloro-2,3-dibenzofuran-2-carboxylate

A

(-)-menthol
2216-51-5

(-)-menthol

B

(R)-6,7-Dichloro-2,3-dihydro-benzofuran-2-carboxylic acid
118206-00-1

(R)-6,7-Dichloro-2,3-dihydro-benzofuran-2-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile for 17h; Ambient temperature;A 95%
B 515 mg
acetaldehyde ethyl menthyl acetal
363603-37-6

acetaldehyde ethyl menthyl acetal

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With acetonyltriphenylphosphonium bromide In methanol; dichloromethane at 20℃; for 0.25h;95%
With CuCl2*H2O In water; acetone for 1h; Hydrolysis; Heating;91%
(2R,5S)-menthone
10458-14-7, 14073-97-3

(2R,5S)-menthone

A

(-)-menthol
2216-51-5

(-)-menthol

B

Neomenthol
2216-52-6

Neomenthol

Conditions
ConditionsYield
With sodium tetrahydroborate; cerium(III) chloride In methanol for 0.0833333h; Yields of byproduct given;A 94%
B n/a
With methanol; sodium tetrahydroborate at 20℃;A 50%
B 31%
With sodium tetrahydroborate In isopropyl alcohol Yield given. Yields of byproduct given. Title compound not separated from byproducts;
methoxyethoxymethyl ether of menthol
123482-46-2

methoxyethoxymethyl ether of menthol

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With cerium(III) chloride In acetonitrile for 1.5h; Heating;94%
4-(2-isopropyl-5-methyl-cyclohexyloxymethyl)-phenol
775356-24-6

4-(2-isopropyl-5-methyl-cyclohexyloxymethyl)-phenol

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With iron(III) chloride In diethyl ether; dichloromethane94%
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl picolinate
38470-12-1

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl picolinate

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With zinc diacetate In methanol; dichloromethane at 38℃; for 3.8h;94%
With methanol; copper diacetate In chloroform at 20℃; for 6h; Inert atmosphere;91%
O-(-)-menthyl S-methyl carbonodithioate
5564-44-3

O-(-)-menthyl S-methyl carbonodithioate

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With 3-azapentane-1,5-diamine at 160℃; for 0.5h; Sealed tube; Microwave irradiation;94%
methanol
67-56-1

methanol

(1R,3R,4S)-p-menth-3-yl (R)-6,7-dichloro-2,3-dibenzofuran-2-carboxylate
118166-31-7

(1R,3R,4S)-p-menth-3-yl (R)-6,7-dichloro-2,3-dibenzofuran-2-carboxylate

A

(-)-menthol
2216-51-5

(-)-menthol

B

methyl (R)-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxylate
118166-28-2

methyl (R)-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxylate

Conditions
ConditionsYield
With toluene-4-sulfonic acid for 20h; Heating;A 81%
B 93%
L-O-(4-Nitrobenzyl)menthol

L-O-(4-Nitrobenzyl)menthol

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 18h; Heating;93%
menthyl β-(trimethylsilyl)ethoxymethyl ether

menthyl β-(trimethylsilyl)ethoxymethyl ether

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With carbon tetrabromide In methanol Irradiation;93%
C54H45F51N2O4

C54H45F51N2O4

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With sodium methylate In methanol; diethyl ether at 20℃;93%
[[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]methyl]benzene
136375-73-0

[[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]methyl]benzene

A

(-)-menthol
2216-51-5

(-)-menthol

B

benzoic acid
65-85-0

benzoic acid

Conditions
ConditionsYield
With bis(acetylacetonate)oxovanadium; methyl 3,5-bis((1H-1,2,4-triazol-1-yl)methyl)benzoate; oxygen; sodium acetate at 120℃; for 48h;A 90%
B 93%
(1S,2R,4R)-1-isopropyl-4-methyl-2-(3-methylbut-2-en-1-yloxy)cyclohexane
180477-54-7

(1S,2R,4R)-1-isopropyl-4-methyl-2-(3-methylbut-2-en-1-yloxy)cyclohexane

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With iodine In dichloromethane at 20℃; for 1h;92%
With 3 A molecular sieve; iodine In dichloromethane at 0 - 20℃; for 1h;92%
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water at 20℃; for 1.5h;86%
With sodium iodide; zirconium(IV) chloride In acetonitrile for 1.5h; Heating;86%
(1S,2R,4S)-1-isopropyl-4-methyl-2-trityloxy-cyclohexane
312493-45-1

(1S,2R,4S)-1-isopropyl-4-methyl-2-trityloxy-cyclohexane

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
With bismuth(III) chloride In acetonitrile at 20℃; for 0.0833333h;92%
(1R,2S,5R)-menthyl 2-(prenyloxymethyl)benzoate
958883-15-3

(1R,2S,5R)-menthyl 2-(prenyloxymethyl)benzoate

(-)-menthol
2216-51-5

(-)-menthol

Conditions
ConditionsYield
Stage #1: (1R,2S,5R)-menthyl 2-(prenyloxymethyl)benzoate With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; water at 20℃; for 6h;
Stage #2: With ytterbium(III) triflate In dichloromethane at 20℃; for 3h;
92%
(-)-menthol
2216-51-5

(-)-menthol

(2R,5S)-menthone
10458-14-7, 14073-97-3

(2R,5S)-menthone

Conditions
ConditionsYield
With Dess-Martin periodane In dichloromethane at 20℃; for 4h;100%
With 1,3,5,7-tetrakis-(4-(diacetoxyiodo)phenyl)adamantane; potassium bromide In water at 20℃; for 4h;100%
With ruthenium trichloride; iodobenzene; potassium peroxomonosulfate In water; acetonitrile at 20℃; for 0.5h;100%
(-)-menthol
2216-51-5

(-)-menthol

dimenthyl sulfite
26510-92-9

dimenthyl sulfite

Conditions
ConditionsYield
With 1,2,3-Benzotriazole; thionyl chloride In dichloromethane at 20℃; Substitution;100%
With thionyl chloride; triethylamine In dichloromethane at -60℃;95%
With pyridine; diethyl ether; chlorosulfurous acid
(-)-menthol
2216-51-5

(-)-menthol

ethyl 3-oxo-3-phenylpropionate
94-02-0

ethyl 3-oxo-3-phenylpropionate

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 3-oxo-3-phenylpropanoate
217473-70-6

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 3-oxo-3-phenylpropanoate

Conditions
ConditionsYield
at 100℃; for 8h;100%
With N-Bromosuccinimide In toluene at 90 - 100℃; for 4h;77%
at 120℃;
at 160℃;
With dmap Dean-Stark; Reflux;
(-)-menthol
2216-51-5

(-)-menthol

phenyl isocyanate
103-71-9

phenyl isocyanate

phenylcarbamic acid (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ester
637336-84-6

phenylcarbamic acid (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ester

Conditions
ConditionsYield
With MoCl2O2(dmf)2 In dichloromethane at 20℃; for 0.333333h;100%
With MoCl2O2(dmf)2 In dichloromethane at 20℃; for 0.333333h; Reagent/catalyst; Inert atmosphere; Sealed tube;100%
Conditions
ConditionsYield
With 1-[bis(trifluoromethanesulfonyl)methyl]-2,3,4,5,6-pentafluorobenzene100%
With 4-(1H,1H-perfluorotetradecyl)-C6F4-CH(SO2CF3)2 In toluene at 70℃; for 14h;99%
With 4-(dimethylamino)pyridine hydrochloride In toluene at 60℃; for 6h;98%
(-)-menthol
2216-51-5

(-)-menthol

chloroacetyl chloride
79-04-9

chloroacetyl chloride

Conditions
ConditionsYield
In benzene Heating;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 12h; Temperature;98.8%
for 5.5h; Reflux;95%
(-)-menthol
2216-51-5

(-)-menthol

2-Bromoacetyl bromide
598-21-0

2-Bromoacetyl bromide

(1R,2S,5R)-menthol bromoacetate
16832-20-5, 32815-12-6, 55284-67-8

(1R,2S,5R)-menthol bromoacetate

Conditions
ConditionsYield
With pyridine In dichloromethane at -78℃; Inert atmosphere;100%
With potassium carbonate In dichloromethane at 0 - 20℃; Inert atmosphere;95%
With N,N-dimethyl-aniline In diethyl ether 1.) 0 deg C, 3 h, 2.) reflux, 3 h;77%
(-)-menthol
2216-51-5

(-)-menthol

bromoacetic acid
79-08-3

bromoacetic acid

(1R,2S,5R)-menthol bromoacetate
16832-20-5, 32815-12-6, 55284-67-8

(1R,2S,5R)-menthol bromoacetate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 3h;100%
With dmap; dicyclohexyl-carbodiimide at 100℃; for 3h;96%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 2h;91%
(-)-menthol
2216-51-5

(-)-menthol

Propiolic acid
471-25-0

Propiolic acid

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl propiolate
65018-52-2

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl propiolate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Reflux; Dean-Stark;100%
With sulfuric acid
With sulfuric acid for 216h; Ambient temperature;
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 25℃; for 6h;
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

(-)-menthol
2216-51-5

(-)-menthol

(L)-menthyl 3-oxobutyrate
59557-05-0

(L)-menthyl 3-oxobutyrate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 3h;100%
With sodium acetate In acetonitrile for 2h; Heating;96%
With triethylamine In acetone for 2h; Heating;92%
phenylglyoxylyl chloride
25726-04-9

phenylglyoxylyl chloride

(-)-menthol
2216-51-5

(-)-menthol

l-menthyl phenylglyoxylate
20229-41-8

l-menthyl phenylglyoxylate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 0℃;100%
With pyridine In toluene for 14h; Ambient temperature;89%
diethylphosphonoacetic acid
3095-95-2

diethylphosphonoacetic acid

(-)-menthol
2216-51-5

(-)-menthol

(diethoxy-phosphoryl)-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
141540-20-7

(diethoxy-phosphoryl)-acetic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In ethyl acetate; toluene at 20℃; Inert atmosphere;100%
With triethylamine; 2-chloropyridinium iodide
oxalyl dichloride
79-37-8

oxalyl dichloride

(-)-menthol
2216-51-5

(-)-menthol

2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoacetic acid
70894-19-8

2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoacetic acid

Conditions
ConditionsYield
Stage #1: oxalyl dichloride; (-)-menthol In diethyl ether at 0 - 23℃; for 1.5h; Inert atmosphere;
Stage #2: With water In diethyl ether at 0 - 23℃; Inert atmosphere;
100%
1) CH2Cl2, room temperature, 2) hydrolysis; Multistep reaction;
In diethyl ether; dichloromethane at 0 - 20℃; for 18h;
trans-chrotonyl chloride
625-35-4, 3488-22-0, 10487-71-5

trans-chrotonyl chloride

(-)-menthol
2216-51-5

(-)-menthol

l-menthyl 3-butenoate
109977-81-3

l-menthyl 3-butenoate

Conditions
ConditionsYield
With triethylamine at 0℃;100%
3-(trimethylsilyl)propanoyl chloride
18187-31-0

3-(trimethylsilyl)propanoyl chloride

(-)-menthol
2216-51-5

(-)-menthol

3-trimethylsilanyl-propionic acid-((1R)-menthyl ester)
133124-91-1

3-trimethylsilanyl-propionic acid-((1R)-menthyl ester)

Conditions
ConditionsYield
With pyridine100%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

(-)-menthol
2216-51-5

(-)-menthol

(1R,2S,5R)-menthyl chloroformate
14602-86-9

(1R,2S,5R)-menthyl chloroformate

Conditions
ConditionsYield
With pyridine In tetrachloromethane at 55 - 60℃; for 6h;100%
Stage #1: bis(trichloromethyl) carbonate With pyridine In toluene at 0℃; for 0.25h; Inert atmosphere;
Stage #2: (-)-menthol In toluene at 20℃; for 15h; Inert atmosphere;
100%
Stage #1: bis(trichloromethyl) carbonate With pyridine In toluene at 0℃; Inert atmosphere;
Stage #2: (-)-menthol In toluene at 0 - 20℃; Inert atmosphere;
100%
(-)-menthol
2216-51-5

(-)-menthol

(E)-2-oxo-4-phenyl-3-butenoic acid
1914-59-6

(E)-2-oxo-4-phenyl-3-butenoic acid

2-oxo-4-phenylbut-3-enoic acid 2-isopropyl-5-methylcyclohexyl ester
110143-65-2

2-oxo-4-phenylbut-3-enoic acid 2-isopropyl-5-methylcyclohexyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 5h; Heating;100%
With toluene-4-sulfonic acid In toluene for 3h; Heating;79%
With toluene-4-sulfonic acid In toluene Heating;79%
(-)-menthol
2216-51-5

(-)-menthol

benzene
75067-08-2

benzene

<<(-)-menthyloxy>(tosyloxy)iodo>benzene
128328-14-3, 128328-15-4

<<(-)-menthyloxy>(tosyloxy)iodo>benzene

Conditions
ConditionsYield
In dichloromethane100%
(-)-menthol
2216-51-5

(-)-menthol

(1S,2S,4R)-2-bromo-1-isopropyl-4-methylcyclohexane
87161-57-7

(1S,2S,4R)-2-bromo-1-isopropyl-4-methylcyclohexane

Conditions
ConditionsYield
With carbon tetrabromide; tris[4-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctyloxy)phenyl]phosphane In toluene at 50℃; for 4h;100%
With 1-bromo-N,N,2-trimethyl-1-propen-1-amine; methyloxirane In dichloromethane 1.) -78 deg C to r.t., 2.) r.t., overnight;97%
With bromine; triethylamine; triphenylphosphine at 20℃; for 1.5h; Substitution;86%
With chloro-trimethyl-silane; lithium bromide In acetonitrile for 20h; Heating;72%
With 4-methylurazole; methyl bromide; triphenylphosphine 1) THF, 0 deg C, 2) room temperature, 6 h; Yield given. Multistep reaction;
(-)-menthol
2216-51-5

(-)-menthol

(1R,2S,5R)-(-)-menthyl phosphorodichloridite
95456-31-8

(1R,2S,5R)-(-)-menthyl phosphorodichloridite

Conditions
ConditionsYield
With phosphorus trichloride In tetrahydrofuran for 1h; Ambient temperature;100%
With phosphorus trichloride Inert atmosphere;98%
Stage #1: (-)-menthol With sodium hydride In tetrahydrofuran at 20℃; Inert atmosphere;
Stage #2: With phosphorus trichloride In tetrahydrofuran Inert atmosphere;
64%
(-)-menthol
2216-51-5

(-)-menthol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl methanesulfonate
61548-81-0

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 16h; Inert atmosphere; Schlenk technique;100%
With triethylamine In dichloromethane at 0 - 20℃; for 12h;100%
With 1-methyl-1H-imidazole; triethylamine In toluene at 20 - 25℃; for 1h; Inert atmosphere;99%
(-)-menthol
2216-51-5

(-)-menthol

Dichlorophenylphosphine
644-97-3

Dichlorophenylphosphine

(-)-(o-menthyl)chlorophenylphosphine

(-)-(o-menthyl)chlorophenylphosphine

Conditions
ConditionsYield
Stage #1: (-)-menthol With n-butyllithium In tetrahydrofuran; hexane at 0℃; Inert atmosphere;
Stage #2: Dichlorophenylphosphine In tetrahydrofuran; hexane at -78 - 20℃; for 15h; Inert atmosphere;
100%
With R3N
With pyridine
(-)-menthol
2216-51-5

(-)-menthol

ethyl vinyl ether
109-92-2

ethyl vinyl ether

acetaldehyde ethyl menthyl acetal
363603-37-6

acetaldehyde ethyl menthyl acetal

Conditions
ConditionsYield
With trifluoroacetic acid at 20℃; for 96h;100%
With acetonyltriphenylphosphonium bromide In dichloromethane at 20℃; for 0.0833333h;99%
With acetonyltriphenylphosphonium bromide In dichloromethane for 0.0833333h; Ambient temperature;92%
With hydrogenchloride
(-)-menthol
2216-51-5

(-)-menthol

acetic anhydride
108-24-7

acetic anhydride

L-menthyl acetate
2623-23-6

L-menthyl acetate

Conditions
ConditionsYield
zeolite HSZ-360 In neat (no solvent) at 60℃; for 1h; Product distribution; direct acetylation of phenols and alcohols, catalyst reusable without activity loss;100%
zeolite HSZ-360 In neat (no solvent) at 60℃; for 1h;100%
With polystyrene-bound tetrafluorophenylbis(triflyl)methane100%
(-)-menthol
2216-51-5

(-)-menthol

acetic acid
64-19-7

acetic acid

L-menthyl acetate
2623-23-6

L-menthyl acetate

Conditions
ConditionsYield
With methanesulfonic acid at 30 - 35℃; for 2h;100%
With copper(II) nitrate for 3.5h; Heating;98%
LaY zeolite at 116℃; for 10h; Acetylation;98%
(-)-menthol
2216-51-5

(-)-menthol

formic acid ethyl ester
109-94-4

formic acid ethyl ester

menthyl formate
61949-23-3

menthyl formate

Conditions
ConditionsYield
With copper(II) nitrate for 3.5h; Heating;100%
With bismuth(III) chloride for 1h; Heating;95%
With Silphos at 20℃; for 1h;94%
3-ethoxy-2-methylacrolein
62055-46-3

3-ethoxy-2-methylacrolein

(-)-menthol
2216-51-5

(-)-menthol

3-[2-isopropyl-5-methylcyclohexyloxy-(1R,2S,5R)]-2-methyl-2E-propenal
250267-09-5

3-[2-isopropyl-5-methylcyclohexyloxy-(1R,2S,5R)]-2-methyl-2E-propenal

Conditions
ConditionsYield
With toluene-4-sulfonic acid under 23 Torr; for 24h; Substitution;100%
(-)-menthol
2216-51-5

(-)-menthol

(S)-chlorofluoroacetic acid
25197-75-5

(S)-chlorofluoroacetic acid

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S)-2-chloro-2-fluoroacetate

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S)-2-chloro-2-fluoroacetate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; Esterification; Title compound not separated from byproducts;100%
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