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Cas:22677-21-0
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:22677-21-0
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inquiry(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Basic information Product Name: (R)-(+)-4-HYDROXY-2-PYRROLIDINONE Synonyms: (R)-(+)-4-HYDROXY-2-PYRROLIDINONE;
Cas:22677-21-0
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:22677-21-0
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
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Min.Order:1 Kilogram
FOB Price: $250.0 / 300.0
Type:Trading Company
inquiryTIANFUCHEM--22677-21-0--High purity (R)-(+)-4-HYDROXY-2-PYRROLIDINONE factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had establ
Cas:22677-21-0
Min.Order:1 Metric Ton
FOB Price: $2000.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:22677-21-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:22677-21-0
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiry(R)-(+)-4-HYDROXY-2-PYRROLIDINONE CAS:22677-21-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit
Cas:22677-21-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:22677-21-0
Min.Order:4 Kilogram
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Type:Lab/Research institutions
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:22677-21-0
Min.Order:0 Metric Ton
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Type:Other
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Min.Order:0
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Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:22677-21-0
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryHunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
Cas:22677-21-0
Min.Order:0 Metric Ton
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Type:Manufacturers
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Cas:22677-21-0
Min.Order:0
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Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:22677-21-0
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryProduct name (S)-4-Hydroxy-2-pyrrolidinone Content ≥98% CAS NO. 68108-18-9 Package Structure Formula Appearance:Det
Cas:22677-21-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:white to light yellow crystal powde Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:intermediate in the preparation
Cas:22677-21-0
Min.Order:10 Gram
Negotiable
Type:Trading Company
inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:22677-21-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:22677-21-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is
Cas:22677-21-0
Min.Order:100 Kilogram
FOB Price: $100.0 / 150.0
Type:Other
inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:22677-21-0
Min.Order:0
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Type:Lab/Research institutions
inquiry"HANGZHOU TIANYE CHEMICALS Co.LTD , Located in Eastern Science and Innovation Park Hangzhou .We are a high-tech enterprise specialized in technical research and development, production, development and trade of chemical products. We supply Multiple s
(R)-(+)-4-Hydroxy-2-pyrrolidinone cas 22677-21-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:22677-21-0
Min.Order:0
Negotiable
Type:Other
inquiryBest quality with low priceAppearance:white to light yellow crystal powder Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai
Cas:22677-21-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta
Cas:22677-21-0
Min.Order:0
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Type:Lab/Research institutions
inquiry22677-21-0 Application:intermediate
Cas:22677-21-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryethyl (L)-4-chloro-3-hydroxybutyrate
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With ammonium hydroxide at 80℃; for 3h; | 82% |
1-(1'-phenylethyl)-4-phenylmethoxypyrrolidin-2-one
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With ammonia; sodium In tetrahydrofuran for 1h; | 51% |
(4R)-4-hydroxy-1-<(1S)-1-phenylethyl>pyrrolidin-2-one
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With ammonia; lithium In tetrahydrofuran; tert-butyl alcohol at -60℃; for 0.25h; |
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide at 40℃; for 0.75h; Yield given; |
(R)-4-hydroxy-2-pyrrolidinone
3(R)-hydroxy-4-aminobutyric acid ethyl ester
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
In ethanol |
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
In methanol |
(R)-4-hydroxy-2-pyrrolidinone
tert-butyldimethylsilyl chloride
(4R)-4-((tert-butyl(dimethyl)silyl)oxy)pyrrolidin-2-one
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 0.5h; Condensation; | 99% |
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 12h; | 95% |
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 3h; | 91% |
(R)-4-hydroxy-2-pyrrolidinone
tert-butylchlorodiphenylsilane
(R)-4-[tert-butyl(diphenyl)silanyloxy]pyrrolidin-2-one
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 0℃; for 0.5h; | 96% |
(R)-4-hydroxy-2-pyrrolidinone
(R)-4-Amino-3-hydroxybutanoic acid
Conditions | Yield |
---|---|
With hydrogenchloride for 4h; Heating; | 94% |
With lithium hydroxide for 24h; Ambient temperature; | 89% |
With hydrogenchloride for 2h; Heating; | 70% |
With barium dihydroxide | |
With hydrogenchloride for 10h; Heating; Yield given; |
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 20℃; Cooling with ice; | 81% |
4-(4,6-dichloropyridin-2-yl)morpholine
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; sodium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane; water at 100℃; for 2h; Inert atmosphere; | 78% |
Conditions | Yield |
---|---|
With pyridine; dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h; | 60% |
(R)-4-hydroxy-2-pyrrolidinone
7-bromo-2-(difluoro(4-fluorophenyl)methyl)-4-(methylthio)quinazoline
(R)-1-(2-(difluoro(4-fluorophenyl)methyl)-4-(methylthio)quinazolin-7-yl)-4-hydroxypyrrolidin-2-one
Conditions | Yield |
---|---|
With caesium carbonate; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; Inert atmosphere; | 48% |
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With palladium diacetate; potassium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 80℃; Inert atmosphere; | 39% |
(R)-4-hydroxy-2-pyrrolidinone
1-bromo-4-iodo-2-methylbenzene
(R)-1-(4-bromo-3-methyl-phenyl)-4-hydroxy-pyrrolidin-2-one
Conditions | Yield |
---|---|
With caesium carbonate; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 110℃; Inert atmosphere; | 38% |
(R)-4-hydroxy-2-pyrrolidinone
(S)-4-azidopyrrolidin-2-one
Conditions | Yield |
---|---|
Stage #1: (R)-4-hydroxy-2-pyrrolidinone With methanesulfonyl chloride; triethylamine In dichloromethane at 20℃; for 1h; Stage #2: With sodium azide In N,N-dimethyl-formamide at 60℃; for 3h; | 32% |
(R)-4-hydroxy-2-pyrrolidinone
1-Chloro-4-(chloromethyl)benzene
Conditions | Yield |
---|---|
Stage #1: (R)-4-hydroxy-2-pyrrolidinone With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.25h; Stage #2: 1-Chloro-4-(chloromethyl)benzene In N,N-dimethyl-formamide at 20℃; | 30% |
(R)-4-hydroxy-2-pyrrolidinone
ethyl bromoacetate
ethyl (R)-4-hydroxy-2-oxo-1-pyrrolidineacetate
Conditions | Yield |
---|---|
With sodium hydride; 1,1,1,3,3,3-hexamethyl-disilazane 1) reflux, 2 h; 2) acetonitrile, reflux, 30 min; Multistep reaction; |
Conditions | Yield |
---|---|
With sodium phenylsulfonate at 15℃; Product distribution; Further Variations:; Reagents; electrode material; current density; Oxidation; methoxylation; Electrochemical reaction; | |
With sodium phenylsulfonate at 15℃; Oxidation; methoxylation; Electrochemical reaction; | |
With sodium phenylsulfonate at 20℃; Etherification; Electrolysis; |
(R)-4-hydroxy-2-pyrrolidinone
(4R)-4-((tert-butyl(dimethyl)silyl)oxy)pyrrolidin-2-one
Conditions | Yield |
---|---|
Substitution; |
(R)-4-hydroxy-2-pyrrolidinone
[2-(4-(bromomethyl)phenyl)ethyl]carbamic acid tert-butyl ester
tert-butyl [2-(4-{[(4R)-4-hydroxy-2-oxopyrrolidin-1-yl]methyl}phenyl)ethyl]carbamate
Conditions | Yield |
---|---|
Stage #1: (R)-4-hydroxy-2-pyrrolidinone; [2-(4-(bromomethyl)phenyl)ethyl]carbamic acid tert-butyl ester With sodium hydride In N,N-dimethyl-formamide at 1 - 30℃; for 1h; Stage #2: With potassium hydrogensulfate; water In ethyl acetate; N,N-dimethyl-formamide |
Conditions | Yield |
---|---|
With triphenylphosphine In tetrahydrofuran | |
With triphenylphosphine In tetrahydrofuran |
6-bromo-N-[(2,6-dimethylphenyl)methyl]-2,3-dimethylimidazo[1,2-a]pyridin-8-amine
(R)-4-hydroxy-2-pyrrolidinone
Conditions | Yield |
---|---|
With potassium carbonate; N,N`-dimethylethylenediamine; copper(l) iodide In 1,4-dioxane at 140℃; for 14h; Ullmann-type coupling; Microwave synthesizer; |
(R)-4-hydroxy-2-pyrrolidinone
methyl iodide
4-methoxy-1-methylpyrrolidin-2-one
Conditions | Yield |
---|---|
Stage #1: (R)-4-hydroxy-2-pyrrolidinone With sodium hydride In tetrahydrofuran at 20 - 50℃; for 22h; Stage #2: methyl iodide In tetrahydrofuran at 20℃; for 70h; |
(R)-4-hydroxy-2-pyrrolidinone
4-(4-bromo-6-methylquinolin-2-yl)-2,3,4,5-tetrahydro-1,4-benzothiazepine 1,1-dioxide
(4R)-1-[2-(1,1-dioxido-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-6-methylquinolin-4-yl]-4-hydroxypyrrolidin-2-one
Conditions | Yield |
---|---|
With copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; potassium carbonate In diethylene glycol dimethyl ether at 140℃; for 2h; Microwave irradiation; | 160 mg |
Conditions | Yield |
---|---|
With dmap In dichloromethane at 0 - 20℃; for 16h; |
(R)-4-hydroxy-2-pyrrolidinone
di-tert-butyl dicarbonate
tert-butyldimethylsilyl chloride
Conditions | Yield |
---|---|
Stage #1: (R)-4-hydroxy-2-pyrrolidinone; di-tert-butyl dicarbonate Stage #2: tert-butyldimethylsilyl chloride With lithium triethylborohydride |
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