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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2,5-Difluorophenol Manufacturer/High quality/Best price/In stock

Cas:2713-31-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

High Quality and Best Price of 2,5-Difluorophenol from Henan Tianfu Chemical: Henan Tianfu Chemical Co.,LTD was built in 2009 with an ISO certificate in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had es

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 2713-31-7 with fast shipping

Cas:2713-31-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2713-31-7

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,5-Difluorophenol;2,5-Difluorophenol;

Cas:2713-31-7

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Shanghai Minstar Chemical Co., Ltd

Product Name: 2,5-Difluorophenol Synonyms: 2,5-DIFLUOROPHENOL;Phenol,2,5-difluoro-;2,5-Difluorphenol;2,5-Difluorophenol,97%;2,5-Difluorophenol 97%;2,5-Difluorophenol,96%;5-Difluorophenol;1,4-Difluoro-2-hydroxybenzene CAS: 2713-31-7 MF: C6

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 15.0

Type:Lab/Research institutions

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2,5-difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Manufacturers

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2,5-Difluorophenol cas no. 2713-31-7 98%

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Manufacturers

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Sealed in a cool ,dry and microtherm place , avoid light . Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:It is an impo

2713-31-7 supplier in China

Cas:2713-31-7

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Manufacturers

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Nanjing Fred Technology Co.,Ltd.

Fredchem focus on CRO/CMO business and its own R&D of API/Intermediates Package:Kilograms/MT Application:Pharmaceutical field Transportation:According to customer request Port:Shanghai

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our?company?has?been?in?existence?for?10?years?since?its?establishment.?We?have?our?own?unique?team.?The??company?integrates?independent?research?and?development,?production?and?sales.?We?have?established?famous??brands?at?home?and?abroad.?At?present

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Trading Company

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:intermediate

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

2,5-Difluorophenol cas 2713-31-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2,5-Difluorophenol cas 2713-31-7

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:white crystalline mass Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:10G/bottle 1kg/tin 5kg/tin 25kg/carton Application:1. Chemical raw materials 2. Used as an analytical reage

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2,5-Difluorophenol

Cas:2713-31-7

Min.Order:0

Negotiable

Type:Other

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Synthetic route

2,4,5-trifluorobenzoic acid
446-17-3

2,4,5-trifluorobenzoic acid

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

Conditions
ConditionsYield
With water; sodium hydroxide at 80 - 155℃; for 35h; Sealed tube;94.1%
para-difluorobenzene
540-36-3

para-difluorobenzene

A

2,4-difluorophenol
367-27-1

2,4-difluorophenol

B

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

Conditions
ConditionsYield
With dihydrogen peroxide In acetonitrile at 60℃; for 0.416667h;A 6%
B 94%
3-fluorophenol
372-20-3

3-fluorophenol

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

Conditions
ConditionsYield
With acetic acid; Selectfluor; eosin y In water at 20℃; for 6h; Irradiation; Green chemistry;70%
2,5-difluoroaniline
367-30-6

2,5-difluoroaniline

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

para-difluorobenzene
540-36-3

para-difluorobenzene

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

Conditions
ConditionsYield
Yield given. Multistep reaction;
para-difluorobenzene
540-36-3

para-difluorobenzene

A

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

B

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

C

4H/5H-3,3,4,5,6,6-Hexafluor-cyclohexen
703-16-2

4H/5H-3,3,4,5,6,6-Hexafluor-cyclohexen

D

3,3,6,6-tetrafluoro-1,4-cyclohexadiene
22060-77-1

3,3,6,6-tetrafluoro-1,4-cyclohexadiene

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; fluorine In trichlorofluoromethane at -25℃; for 3h; Further byproducts given. Title compound not separated from byproducts;
ferrous ammonium sulphate

ferrous ammonium sulphate

Trimethyl borate
121-43-7

Trimethyl borate

para-difluorobenzene
540-36-3

para-difluorobenzene

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

Conditions
ConditionsYield
With hydrogenchloride; n-butyllithium; dihydrogen peroxide In tetrahydrofuran; hexane; toluene
With hydrogenchloride; n-butyllithium; dihydrogen peroxide In tetrahydrofuran; hexane; toluene
para-difluorobenzene
540-36-3

para-difluorobenzene

A

4-Fluorophenol
371-41-5

4-Fluorophenol

B

2,4-difluorophenol
367-27-1

2,4-difluorophenol

C

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

D

hydrogen fluoride
7664-39-3

hydrogen fluoride

Conditions
ConditionsYield
With dihydrogen peroxide In acetonitrile at 60℃; for 15h; Catalytic behavior;
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

N,N-diethylcarbamyl chloride
88-10-8

N,N-diethylcarbamyl chloride

O-2,5-difluorophenyl N,N-diethylcarbamate
1207163-57-2

O-2,5-difluorophenyl N,N-diethylcarbamate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 70℃; for 13.5h;100%
Stage #1: 2,5-difluorophenol With sodium hydroxide In tetrahydrofuran for 0.166667h;
Stage #2: N,N-diethylcarbamyl chloride In tetrahydrofuran at 20℃; for 24h;
92%
Stage #1: 2,5-difluorophenol With sodium hydroxide In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: N,N-diethylcarbamyl chloride In tetrahydrofuran at 20℃; for 24h;
Stage #1: 2,5-difluorophenol With sodium hydroxide In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: N,N-diethylcarbamyl chloride In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

1,4-difluoro-2-(trimethylsilyloxy)benzene

1,4-difluoro-2-(trimethylsilyloxy)benzene

Conditions
ConditionsYield
at 170℃; for 1h;99%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

propargyl bromide
106-96-7

propargyl bromide

1,4-difluoro-2-(prop-2-yn-1-yloxy)benzene

1,4-difluoro-2-(prop-2-yn-1-yloxy)benzene

Conditions
ConditionsYield
Stage #1: 2,5-difluorophenol; propargyl bromide With sodium carbonate In acetone at 60℃; for 8.5h;
Stage #2: In acetone at 25℃; for 15h;
99%
With potassium carbonate In acetone for 24h; Inert atmosphere; Reflux;96.7%
With caesium carbonate In acetonitrile92%
With potassium carbonate In acetone at 60℃; for 24h; Inert atmosphere;88%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-tert-butyldimethylsilyloxy-2,5-difluorobenzene
179420-99-6

1-tert-butyldimethylsilyloxy-2,5-difluorobenzene

Conditions
ConditionsYield
Stage #1: 2,5-difluorophenol With sodium hydride In N,N-dimethyl-formamide for 0.5h; cooling;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide for 1h;
94%
Stage #1: 2,5-difluorophenol With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide at 20℃; for 15h;
80%
In N,N-dimethyl-formamide; mineral oil26.65 g (94%)
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

aniline
62-53-3

aniline

2,5-difluoro-4-phenylazophenol
847872-05-3

2,5-difluoro-4-phenylazophenol

Conditions
ConditionsYield
Stage #1: aniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃;
Stage #2: 2,5-difluorophenol With sodium hydroxide In water
Stage #3: With hydrogenchloride more than 3 stages;
93%
Stage #1: aniline With hydrogenchloride; sodium nitrite In water
Stage #2: 2,5-difluorophenol With sodium hydroxide; urea In water at 0 - 20℃;
74%
N-(2-nitro-5-chlorophenyl)-N-methylcarbamic acid t-butyl ester
299176-17-3

N-(2-nitro-5-chlorophenyl)-N-methylcarbamic acid t-butyl ester

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

tert-butyl [5-(2,5-difluorophenoxy)-2-nitrophenyl]methylcarbamate
1072003-46-3

tert-butyl [5-(2,5-difluorophenoxy)-2-nitrophenyl]methylcarbamate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 80℃; for 10h; Inert atmosphere;92%
formaldehyd
50-00-0

formaldehyd

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

3,6-difluoro-2-(hydroxymethyl)phenol
1244949-79-8

3,6-difluoro-2-(hydroxymethyl)phenol

Conditions
ConditionsYield
With sodium metaborate tetrahydrate In water at 40℃; for 12h; Green chemistry; regioselective reaction;92%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

3,4-bis(4-methoxyphenyl)-6-chloropyridazine
67820-94-4

3,4-bis(4-methoxyphenyl)-6-chloropyridazine

3,4-bis(4-methoxyphenyl)-6-(2,5-difluorophenoxy)pyridazine

3,4-bis(4-methoxyphenyl)-6-(2,5-difluorophenoxy)pyridazine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 150℃; for 24h;91.5%
at 150℃; for 24h;91.5%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

chloromethyl methyl ether
107-30-2

chloromethyl methyl ether

1,4-difluoro-2-(methoxymethoxy)benzene
749230-16-8

1,4-difluoro-2-(methoxymethoxy)benzene

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 2h;91%
Stage #1: 2,5-difluorophenol With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: chloromethyl methyl ether In dichloromethane at 20℃; for 16h;
77.97%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

(S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester
101469-92-5

(S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester

tert-butyl (R)-3-(2,5-difluorophenoxy)pyrrolidine-1-carboxylate

tert-butyl (R)-3-(2,5-difluorophenoxy)pyrrolidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 2,5-difluorophenol; (S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: With di-tert-butyl-diazodicarboxylate In tetrahydrofuran at 20℃;
90%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

dimethyl sulfate
77-78-1

dimethyl sulfate

2,5-difluoroanisole
75626-17-4

2,5-difluoroanisole

Conditions
ConditionsYield
With potassium carbonate In acetone for 2h; Heating;89%
With potassium carbonate In acetone for 2h; Reflux;81.4%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

1-(2-methoxyphenyl)-1H-pyrazol
102908-37-2

1-(2-methoxyphenyl)-1H-pyrazol

1-(2',5'-difluoro-3-methoxybiphenyl-2-yl)-1H-pyrazole
1373210-92-4

1-(2',5'-difluoro-3-methoxybiphenyl-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With [Ru(MesCO2)2(p-cymene)]; potassium carbonate; p-toluenesulfonyl chloride In toluene at 120℃; for 18h; Inert atmosphere; chemoselective reaction;89%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

(hex-1-en-3-yl)methyl carbonate
83135-00-6

(hex-1-en-3-yl)methyl carbonate

(R)-1,4-difluoro-2-(hex-1-en-3-yloxy)benzene

(R)-1,4-difluoro-2-(hex-1-en-3-yloxy)benzene

Conditions
ConditionsYield
With (R,R)-(−)-2,3-bis(t-butylmethylphosphino)quinoxaline; chloro(1,5-cyclooctadiene)rhodium(I) dimer In dichloromethane at 20℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube; enantioselective reaction;88%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

2-bromo-3,6-difluoro phenol
1208077-18-2

2-bromo-3,6-difluoro phenol

Conditions
ConditionsYield
With N-Bromosuccinimide In tetrahydrofuran at -40℃; for 2h;85.3%
With N-Bromosuccinimide In tetrahydrofuran at -40 - 20℃; for 1h;57%
With N-Bromosuccinimide; isopropylamine In tetrahydrofuran at -40 - 20℃; for 0.5h;51%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

benzyl bromide
100-39-0

benzyl bromide

1-(benzyloxy)-2,5-difluorobenzene
152434-79-2

1-(benzyloxy)-2,5-difluorobenzene

Conditions
ConditionsYield
With potassium carbonate In acetone Heating;84%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

Trifluoro-methanesulfonic acid 2,5-difluoro-phenyl ester
211512-93-5

Trifluoro-methanesulfonic acid 2,5-difluoro-phenyl ester

Conditions
ConditionsYield
With pyridine In dichloromethane for 4h; Ambient temperature;84%
formaldehyd
50-00-0

formaldehyd

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

C13H8F4O2

C13H8F4O2

Conditions
ConditionsYield
With phosphoric acid In toluene at 90℃; for 20h;82%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

4-bromo-2,5-difluoro phenol
486424-36-6

4-bromo-2,5-difluoro phenol

Conditions
ConditionsYield
With bromine In chloroform at 0 - 20℃; for 3h;81.05%
With bromine In chloroform for 3h;70.2%
With bromine In chloroform for 3h;70.2%
With bromine; trifluoroacetic acid at 20℃;
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

4-Fluoronitrobenzene
350-46-9

4-Fluoronitrobenzene

1,4-difluoro-2-(4-nitrophenoxy)benzene
1414356-66-3

1,4-difluoro-2-(4-nitrophenoxy)benzene

Conditions
ConditionsYield
Stage #1: 4-Fluoronitrobenzene With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 25℃; for 2.33333h; Inert atmosphere;
Stage #2: 2,5-difluorophenol With copper(l) chloride In N,N-dimethyl-formamide; mineral oil at 100℃; for 12h;
81%
Stage #1: 4-Fluoronitrobenzene With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 25℃; for 2.33333h; Inert atmosphere;
Stage #2: 2,5-difluorophenol; copper(l) chloride In N,N-dimethyl-formamide; mineral oil at 25 - 100℃; for 12.1667h;
81%
Stage #1: 4-Fluoronitrobenzene With sodium hydride In N,N-dimethyl-formamide at 0 - 25℃; for 2.33333h;
Stage #2: 2,5-difluorophenol With copper(l) chloride In N,N-dimethyl-formamide at 25 - 100℃; for 12h;
81%
Stage #1: 4-Fluoronitrobenzene With sodium hydride In N,N-dimethyl-formamide at 0 - 25℃; for 2.33h;
Stage #2: 2,5-difluorophenol With copper(l) chloride In N,N-dimethyl-formamide at 25 - 100℃; for 12.13h;
81%
Stage #1: 4-Fluoronitrobenzene With sodium hydride In N,N-dimethyl-formamide at 0 - 25℃; for 2.33333h;
Stage #2: 2,5-difluorophenol With copper(l) chloride In dichloromethane at 25 - 100℃; for 12h;
81%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

propargyl bromide
106-96-7

propargyl bromide

2,4-difluoro-1-(prop-2-yn-1-yloxy)benzene
672946-37-1

2,4-difluoro-1-(prop-2-yn-1-yloxy)benzene

Conditions
ConditionsYield
With potassium carbonate In acetone Heating / reflux;80%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

para-methylphenylmagnesium bromide
4294-57-9

para-methylphenylmagnesium bromide

4-fluoro-4'-methylbiphenyl-2-ol

4-fluoro-4'-methylbiphenyl-2-ol

Conditions
ConditionsYield
With (bis(tricyclohexyl)phosphine)palladium(II) dichloride In tetrahydrofuran at 50℃; for 24h; Inert atmosphere;79%
With (bis(tricyclohexyl)phosphine)palladium(II) dichloride In tetrahydrofuran at 50℃; for 24h;79%
4-[4-(3-hydroxypropyl)phenyl]-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester
642487-34-1

4-[4-(3-hydroxypropyl)phenyl]-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

4-{4-[3-(2,5-difluorophenoxy)propyl]phenyl}-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester
642487-38-5

4-{4-[3-(2,5-difluorophenoxy)propyl]phenyl}-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester

Conditions
ConditionsYield
With tributylphosphine; N-ethyl-N,N-diisopropylamine; 1,1'-azodicarbonyl-dipiperidine In toluene at 20 - 60℃; for 3h;77%
6-(4-hydroxypiperidin-1-yl)-N-isopentylpyridazine-3-carboxamide
944808-07-5

6-(4-hydroxypiperidin-1-yl)-N-isopentylpyridazine-3-carboxamide

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

C21H26F2N4O2

C21H26F2N4O2

Conditions
ConditionsYield
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 25℃; for 0.5h; Mitsunobu reaction;70%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

2,4,5-tribromo-3,6-difluorophenol

2,4,5-tribromo-3,6-difluorophenol

Conditions
ConditionsYield
With bromine; iron In various solvent(s) Heating;66.3%
Ethyl 2-butynoate
4341-76-8

Ethyl 2-butynoate

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

3-(2,5-difluoro-phenoxy)-but-2-enoic acid ethyl ester
1191998-38-5

3-(2,5-difluoro-phenoxy)-but-2-enoic acid ethyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 130℃; for 2h;63%
2,5-difluorophenol
2713-31-7

2,5-difluorophenol

cis-3-hydroxycyclobutylcarboxylic acid methyl ester
63485-50-7

cis-3-hydroxycyclobutylcarboxylic acid methyl ester

(trans)-methyl 3-(2,5-difluorophenoxy)cyclobutanecarboxylate

(trans)-methyl 3-(2,5-difluorophenoxy)cyclobutanecarboxylate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 72h;63%
4-chloro-3-iodopyridin-2-ylamine
417721-69-8

4-chloro-3-iodopyridin-2-ylamine

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

4-(2,5-difluorophenoxy)-3-iodopyridin-2-amine
1345854-91-2

4-(2,5-difluorophenoxy)-3-iodopyridin-2-amine

Conditions
ConditionsYield
Stage #1: 4-chloro-3-iodopyridin-2-ylamine; 2,5-difluorophenol With 1,8-diazabicyclo[5.4.0]undec-7-ene In 1-methyl-pyrrolidin-2-one at 170℃; for 6h; Microwave irradiation;
Stage #2: With sodium hydroxide In 1-methyl-pyrrolidin-2-one; water
62.1%

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