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CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

We are the manufacturer of this product in China. Our price is the lowest in China. CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD., founded in 1984, engages in pharmaceutical research, development, production, process design and techni

Cinacalcet hydrochloride high purity, lowest price in China

Cas:364782-34-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Yangzhou Qinyuan Pharmatech Co.,Ltd

Cinacalcet Hydrochloride Cas no. 364782-34-3 Cinacalcet Hydrochloride Intermediates Our products are high quality, good price, quick delivery time and we supply all customers best service in the long-term cooperation as below: 1.Established manu

Cinacalcet Hydrochloride

Cas:364782-34-3

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:cool dry place Package:1kg/foil bag;25kg/drum Application:medicine raw material Transportatio

Manufacturer high quality Cinacalcet hydrochloride Cas 364782-34-3 with good price

Cas:364782-34-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

Cinacalcet hydrochloride CAS No.:364782-34-3 Name: Cinacalcet hydrochloride Synonyms: N-(

High purity Cinacalcet hydrochloride CAS No.:364782-34-3

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cinacalcet Hydrochloride

Cas:364782-34-3

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Shanghai SE Pharm Co., Ltd

1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99.0% Appearan

Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

top Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Cinacalcet Hydrochloride CAS 364782-34-3

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 364782-34-3 with competitive price

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Cinacalcet hydrochloride/ LIDE PHARMA- Factory supply / Best price

Cas:364782-34-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

Cinacalcet hydrochloride CAS364782-34-3

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

Cinacalcet hydrochloride CAS NO 364782-34-3

Cas:364782-34-3

Min.Order:1 Kilogram

Negotiable

Type:Other

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Top Quality Cinacalcet Hydrochloride with Best Price 364782-34-3 with Best Price!

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Naphthalenemethanamine,a-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-,hydrochloride (1:1), (aR)- 364782-34-3

Cas:364782-34-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

About us Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad.

Supply Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $300.0 / 320.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality Cinacalcet hydrochloride CAS 364782-34-3 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Mad

High quality Cinacalcet hydrochloride CAS 364782-34-3

Cas:364782-34-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Naphthalenemethanamine,a-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-,hydrochloride (1:1), (aR)-

Cas:364782-34-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Cinacalcet Hydrochloride manufacturer with low price

Cas:364782-34-3

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

Good Quality Price Powder Cinacalcet hydrochloride

Cas:364782-34-3

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Jilin Artel New Materials Co., LTD

Price, service, company and transport advantage: 1.place of origin china with super quality by reasonable price. 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's custo

BEST PRICE/Irinotecan hydrochloride trihydrate

Cas:364782-34-3

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detaile

Cinacalcet hydrochloride,CAS364782-34-3,GMP,Factory Supply

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: Cinacalcet hydrochloride Synonyms: (R)-Cinacalcet Hydrochloride;Cinacalcet(AMG-073) Hydrochloride;AMG-073 HCl;Cinacalcet hydrochloride N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride;Cinacalce

Cinacalcet hydrochloride supplier best quality

Cas:364782-34-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Fandachem Co.,Ltd

Hangzhou Fandachem Co.,Ltd is China-based top1 exporter and supplier of Cinacalcet hydrochloride 99.9%min,Best Sale, CAS No.: 364782-34-3,please contact for price of Cinacalcet hydrochloride 99.9%min,Best Sale, CAS No.: 364782-34-3 and also you c

Best sale 99.9%min Cinacalcet hydrochloride cas no.: 364782-34-3, Hangzhou Fandachem Co.,Ltd

Cas:364782-34-3

Min.Order:1 Kilogram

FOB Price: $342.0 / 375.0

Type:Other

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Synthetic route

(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide
1601479-86-0

(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 12h; Reflux;100%
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester
21172-43-0

methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester With potassium carbonate; potassium iodide; 1-(n-butyl)-3-methylimidazolium triflate In acetonitrile for 6h; Reflux;
Stage #2: With hydrogenchloride at 50 - 55℃; for 1h; Reagent/catalyst;
98.25%
Stage #1: (R)-1-(1-Naphthyl)ethylamine; methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester With potassium carbonate In toluene for 16h; Reflux;
Stage #2: With hydrogenchloride In water; toluene at 70℃; Reagent/catalyst; Solvent; Temperature; Time;
85%
(R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide
1005450-55-4

(R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide With sodium tetrahydroborate; iodine In tetrahydrofuran at 0 - 75℃; for 6.5h;
Stage #2: With hydrogenchloride In hexane; water for 1h;
96.22%
Stage #1: (R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide With sodium tetrahydroborate; boron trifluoride In tetrahydrofuran; diethylene glycol dimethyl ether at 45 - 60℃;
Stage #2: With hydrogenchloride In toluene Further stages.;
95%
Stage #1: (R)‐N‐(1‐(naphthalen‐1‐yl)ethyl)‐3‐(3‐trifluoromethylphenyl)propanamide With dodecacarbonyl-triangulo-triruthenium; 1,1,3,3-tetramethyldisilazane In toluene at 50℃; for 18h;
Stage #2: With hydrogenchloride In 1,4-dioxane at 50℃;
93%
cinacalcet
226256-56-0

cinacalcet

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In n-heptane; ethyl acetate at 20℃;95%
With hydrogenchloride In acetonitrile at 25 - 55℃; for 0.2h;93.1%
With hydrogenchloride In n-heptane; water; toluene at 25 - 30℃; pH=1 - 2; Product distribution / selectivity;92.55%
(R)-α-methyl-N-[3-[3-trifluoromethylphenyl]propyl]-1-naphthalenemethanamine phosphate

(R)-α-methyl-N-[3-[3-trifluoromethylphenyl]propyl]-1-naphthalenemethanamine phosphate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-α-methyl-N-[3-[3-trifluoromethylphenyl]propyl]-1-naphthalenemethanamine phosphate With sodium hydroxide In water; ethyl acetate at 20℃; for 1h; Inert atmosphere;
Stage #2: With hydrogenchloride In ethyl acetate at 20 - 25℃;
94%
vinyl acetate
108-05-4

vinyl acetate

1-(1-naphthyl)ethanol
57605-95-5

1-(1-naphthyl)ethanol

3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine
104774-87-0

3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: vinyl acetate; 1-(1-naphthyl)ethanol at 30℃; for 12h; Enzymatic reaction;
Stage #2: 3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 25℃;
Stage #3: With hydrogenchloride In water Solvent;
93.3%
cinacalcet L-tartrate

cinacalcet L-tartrate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: cinacalcet L-tartrate With sodium carbonate In water at 15 - 20℃; Inert atmosphere;
Stage #2: With hydrogenchloride In water; acetonitrile at 15 - 20℃; for 0.5h;
92.54%
N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine hydrochloride
1240705-66-1

N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine hydrochloride

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogen; palladium dichloride In methanol; ethyl acetate at 20℃; under 750.075 Torr; for 0.5h; Product distribution / selectivity;92.5%
(R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl-2-ene]-1-naphthalenemethaneamine hydrochloride
1207533-91-2

(R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl-2-ene]-1-naphthalenemethaneamine hydrochloride

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In water; ethyl acetate at 25 - 30℃; Large scale;91%
With palladium 10% on activated carbon; hydrogen; potassium carbonate In methanol at 20 - 25℃; under 1500.15 - 2250.23 Torr; for 3h; pH=4.1;71%
With hydrogen; Raney nickel In methanol; ethyl acetate at 20℃; Product distribution / selectivity; Inert atmosphere;69.6%
With hydrogen; palladium(II) hydroxide In methanol at 5 - 10℃; under 1103.36 Torr; for 3h; Product distribution / selectivity; Autoclave;
Multi-step reaction with 2 steps
1.1: sodium hydrogencarbonate / ethyl acetate; water / 1 h / 20 °C / Inert atmosphere
1.2: 1 h / 20 °C / Inert atmosphere
2.1: hydrogenchloride; hydrogen / 2-5percent w/w palladium on carbon / water; methanol / 20 - 30 °C / Inert atmosphere
View Scheme
2-methylpropane-2-sulfinic acid (1-naphthalen-1-ylethyl)-[3-(3-trifluoromethylphenyl)propyl]amide
1410044-63-1

2-methylpropane-2-sulfinic acid (1-naphthalen-1-ylethyl)-[3-(3-trifluoromethylphenyl)propyl]amide

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In tert-butyl methyl ether; water at 20℃;91%
Sodium 1-hydroxy-3-(3-trifluoromethylphenyl)propane-1-sulfonate
1015421-30-3

Sodium 1-hydroxy-3-(3-trifluoromethylphenyl)propane-1-sulfonate

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride
82572-04-1

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: Sodium 1-hydroxy-3-(3-trifluoromethylphenyl)propane-1-sulfonate; (R)-<1-(1-Naphthyl)ethyl>ammonium chloride With triethylamine-borane In methanol at 20℃; for 16h;
Stage #2: With hydrogenchloride In water at 0℃; for 13h; Reagent/catalyst;
91%
(R)-(1-(naphthalen-1-yl)-ethyl)-[3-(3-trifluoromethyl-phenyl)-prop-2-ynyl]-amine hydrochloride
1093944-40-1

(R)-(1-(naphthalen-1-yl)-ethyl)-[3-(3-trifluoromethyl-phenyl)-prop-2-ynyl]-amine hydrochloride

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogen; 5%-palladium/activated carbon In water; isopropyl alcohol at 20℃; for 3h;90%
With hydrogen; 5%-palladium/activated carbon In isopropyl alcohol at 20℃; under 760.051 Torr; for 3h;90%
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

3-(3-(trifluoromethyl)phenyl)propyl trifluoromethanesulfonate

3-(3-(trifluoromethyl)phenyl)propyl trifluoromethanesulfonate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 3-(3-(trifluoromethyl)phenyl)propyl trifluoromethanesulfonate With potassium hydroxide In toluene for 16h; Reflux;
Stage #2: With hydrogenchloride In water; toluene Temperature;
89%
N-((1R)-1-(1-naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-tritylamine

N-((1R)-1-(1-naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-tritylamine

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In tert-butyl methyl ether; water at 20℃;84%
N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine fumarate

N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine fumarate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; 2-5percent w/w palladium on carbon In methanol; water at 20 - 30℃; Inert atmosphere;83.8%
1-(3-bromopropyl)-3- (trifluoromethyl)benzene
129254-76-8

1-(3-bromopropyl)-3- (trifluoromethyl)benzene

(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: 1-(3-bromopropyl)-3- (trifluoromethyl)benzene; (R)-1-(1-Naphthyl)ethylamine With potassium carbonate In toluene for 7h; Reflux;
Stage #2: With hydrogenchloride In water; toluene at 50℃;
83%
Stage #1: (R)-1-(1-Naphthyl)ethylamine With benzaldehyde at 25 - 30℃; Forster reaction;
Stage #2: 1-(3-bromopropyl)-3- (trifluoromethyl)benzene In 1-methyl-pyrrolidin-2-one at 125 - 130℃; Forster reaction; Further stages;
58%
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

3-[3-(trifluoromethyl)phenyl]propan-1-ol
78573-45-2

3-[3-(trifluoromethyl)phenyl]propan-1-ol

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 3-[3-(trifluoromethyl)phenyl]propan-1-ol With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] In toluene at 110℃; for 6h; Inert atmosphere;
Stage #2: With hydrogenchloride In diethyl ether; hexane; ethyl acetate; toluene Reagent/catalyst; Time;
83%
(R)-3-chloro-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
1273259-52-1

(R)-3-chloro-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-3-chloro-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride With sodium hydrogencarbonate In water; toluene at 15 - 20℃; pH=8 - 9; Inert atmosphere;
Stage #2: With hydrogen; 5% Pd(II)/C(eggshell) In methanol; toluene at 20℃; under 750.075 Torr; Product distribution / selectivity;
82.6%
N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine bisulfate

N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine bisulfate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol at 20℃;80.8%
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

3-[3-(trifluoromethyl)phenyl]propanal
21172-41-8

3-[3-(trifluoromethyl)phenyl]propanal

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 3-[3-(trifluoromethyl)phenyl]propanal With sodium tetrahydroborate; boric acid at 20℃; for 14.5h;
Stage #2: With hydrogenchloride In hexane; water at 20℃; for 3.5h; pH=1 - 3;
80%
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 3-[3-(trifluoromethyl)phenyl]propanal In tetrahydrofuran at -50 - -45℃; for 2.5h;
Stage #2: With titanium(IV) isopropylate In tetrahydrofuran Product distribution / selectivity;
N-[1-(R)-(-)-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane acetate
1025064-29-2

N-[1-(R)-(-)-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane acetate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With sodium chloride In 2-methylpropyl acetate; water at 20℃; Product distribution / selectivity;79.7%
With hydrogenchloride In 2-methylpropyl acetate; water at 5 - 10℃; for 0.5h; Product distribution / selectivity;72.7%
With hydrogenchloride In dichloromethane; water for 0.25h; Product distribution / selectivity;
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

3-(3-trifluoromethylphenyl)propanoic acid
585-50-2

3-(3-trifluoromethylphenyl)propanoic acid

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 3-(3-trifluoromethylphenyl)propanoic acid With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; phenylsilane; 1,2-bis-(diphenylphosphino)ethane In dibutyl ether at 120℃; for 18h; Schlenk technique; Inert atmosphere;
Stage #2: With hydrogenchloride In diethyl ether at -20℃; Schlenk technique; Inert atmosphere;
74%
(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

1-(3-chloropropyl)-3-(trifluoromethyl)benzene
82258-76-2

1-(3-chloropropyl)-3-(trifluoromethyl)benzene

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; 1-(3-chloropropyl)-3-(trifluoromethyl)benzene With potassium carbonate In toluene for 15h; Reflux;
Stage #2: With hydrogenchloride In water; toluene for 60h;
73%
methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester
21172-43-0

methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride
82572-04-1

(R)-<1-(1-Naphthyl)ethyl>ammonium chloride

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In water; toluene for 24h; Inert atmosphere; Reflux;71.8%
N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine citrate

N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine citrate

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine citrate With hydrogen; 2.5% wt Pd/C In methanol Inert atmosphere;
Stage #2: With hydrogenchloride In methanol; water at 25 - 30℃; for 1h; Product distribution / selectivity; Inert atmosphere;
63.9%
(R)-N-[3-[3-(trifluoromethyl)phenyl]-2-propenylimino]-N-[1-(1-naphthyl)ethylamine]
1201910-95-3

(R)-N-[3-[3-(trifluoromethyl)phenyl]-2-propenylimino]-N-[1-(1-naphthyl)ethylamine]

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-N-[3-[3-(trifluoromethyl)phenyl]-2-propenylimino]-N-[1-(1-naphthyl)ethylamine] With 5%-palladium/activated carbon; hydrogen In ethanol at 20℃; under 2250.23 Torr;
Stage #2: With hydrogenchloride In ethanol; isopropyl alcohol
60%
1'-naphthacetophenone
941-98-0

1'-naphthacetophenone

3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine
104774-87-0

3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: 1'-naphthacetophenone; 3‐[3‐(trifluoromethyl)phenyl]propan‐1‐amine With (R)-3,3'-bis(2,4,6-triisopropylphenyl)-1,1'-binaphthyl-2,2'-diylhydrogenphosphate In toluene at 40℃; for 48h; Molecular sieve; Inert atmosphere;
Stage #2: With hydrogenchloride In water; toluene at 0 - 5℃; Reagent/catalyst;
56.7%
1-(3-bromopropyl)-3- (trifluoromethyl)benzene
129254-76-8

1-(3-bromopropyl)-3- (trifluoromethyl)benzene

(R)-1-(1-Naphthyl)ethylamine
3886-70-2

(R)-1-(1-Naphthyl)ethylamine

benzaldehyde
100-52-7

benzaldehyde

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-1-(1-Naphthyl)ethylamine; benzaldehyde at 25 - 30℃;
Stage #2: 1-(3-bromopropyl)-3- (trifluoromethyl)benzene In 1-methyl-pyrrolidin-2-one at 130 - 140℃; for 12h;
Stage #3: With hydrogenchloride; water In 1-methyl-pyrrolidin-2-one; toluene pH=0.5 - 2;
52.1%
(E)-N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide
1095393-66-0

(E)-N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide

cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

Conditions
ConditionsYield
Stage #1: (R)-N-(1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-(E)-acrylamide With dimethylsulfide borane complex In tetrahydrofuran at 0 - 65℃; for 4h;
Stage #2: With methanol at 0℃; for 0.5h;
Stage #3: With hydrogenchloride; water at 0 - 90℃; for 4h; Product distribution / selectivity;
cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

cinacalcet
226256-56-0

cinacalcet

Conditions
ConditionsYield
With sodium carbonate In dichloromethane; water96%
With water; sodium carbonate In di-isopropyl ether at 25℃; for 2.25h; pH=9.5;
cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

benzyl bromide
100-39-0

benzyl bromide

C29H28F3N

C29H28F3N

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 100℃; for 12h; Inert atmosphere;82%
cinacalcet hydrochloride
364782-34-3

cinacalcet hydrochloride

1-(3-bromopropyl)-3- (trifluoromethyl)benzene
129254-76-8

1-(3-bromopropyl)-3- (trifluoromethyl)benzene

(R)-(1-naphthalen-1-ylethyl)-N,N-bis[3-(3-trifluoromethylphenyl)propyl]amine
1271930-15-4

(R)-(1-naphthalen-1-ylethyl)-N,N-bis[3-(3-trifluoromethylphenyl)propyl]amine

Conditions
ConditionsYield
With potassium carbonate In toluene at 110 - 111℃; for 48h;69.03%

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