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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Chlorosalicylic Acid supplier in China

Cas:5106-98-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White powder Storage:Store at RT. Package:1kg/foil bag; 25kg/fiber d

High purity 4-Chlorosalicylic acid CAS 5106-98-9 with factory price

Cas:5106-98-9

Min.Order:1 Kilogram

FOB Price: $90.0 / 150.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Chlorosalicylic Acid

Cas:5106-98-9

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chlorosalicylic acid (COOH=1)

Cas:5106-98-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 5106-98-9 with best price

Cas:5106-98-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Chlorosalicylic acid 5106-98-9

Cas:5106-98-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China Biggest Factory Manufacturer Supply 4-Chlorosalicylic Acid CAS 5106-98-9

Cas:5106-98-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Chlorosalicylic Acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 4-Chloro Salicylic Acid CAS No.: 5106-98-9 Molecule Formula:C7H4ClO3 Molecule Weight:171.56 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

Lower Price 4-Chloro Salicylic Acid on stock

Cas:5106-98-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

5106-98-9 4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-chloro-2-hydroxybenzoic acid cas no. 5106-98-9 98%

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

4-Chlorosalicylic Acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

High quality 4-Chlorosalicylic acid cas NO.: 5106-98-9

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Other

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

4-Chlorosalicylic acid CAS No.5106-98-9

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

4-Chlorosalicylic acid cas 5106-98-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

4-Chlorosalicylic acid cas 5106-98-9

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:off-white to light beige powder Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

4-Chloro-2-HydroxyBenzoicAcid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changzhou Ansciep Chemical Co.,Ltd.

reagent grade ex stockAppearance:white or off-white crystalline powder Storage:Keep away of light,cool place Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:by Fedex, ship or plane

4-chloro-2-hydroxybenzoic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5g Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

4-Chlorosalicylic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-chloro-2-hydroxybenzoic acid

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

4-Chlorosalicylic acid 5106-98-9

Cas:5106-98-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2,4 dichlorobenzoic acid
50-84-0

2,4 dichlorobenzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With pyridine; water; potassium carbonate; copper for 0.25h; sonication;95%
With pyridine; copper; potassium carbonate In water for 2h; Heating;88%
With copper(l) iodide; copper; potassium carbonate at 180℃; under 7355.08 Torr;
With barium dihydroxide; water; copper at 160 - 170℃;
Stage #1: 2,4 dichlorobenzoic acid With sodium carbonate In water at 50 - 75℃;
Stage #2: trans-N,N'-dimethyl-1,2-cyclohexyldiamine; copper(II) sulfate at 100℃; for 4h;
Stage #3: With hydrogenchloride In water at 20℃; Product distribution / selectivity;
para-chlorobenzoic acid
74-11-3

para-chlorobenzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With oxygen; potassium acetate; palladium diacetate; p-benzoquinone In N,N-dimethyl acetamide at 115℃; under 760.051 Torr; for 15h;78%
With sulfuric acid; acetic acid at 60 - 70℃; bei der elektrolytischen Oxydation;
3-monochlorophenol
108-43-0

3-monochlorophenol

sodium ethyl carbonate
17201-44-4

sodium ethyl carbonate

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With carbon dioxide at 165℃; under 7600.51 Torr; for 6h; Temperature; Pressure; Autoclave; regioselective reaction;76.2%
(E)-1-(4-chloro-2-hydroxyphenyl)-3-(dimethylamino)prop-2-en-1-one
135251-11-5

(E)-1-(4-chloro-2-hydroxyphenyl)-3-(dimethylamino)prop-2-en-1-one

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With sulfuryl dichloride for 0.166667h; Ambient temperature;52%
7-chloro-2,3-dimethyl-chromen-4-one

7-chloro-2,3-dimethyl-chromen-4-one

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

2,4 dichlorobenzoic acid
50-84-0

2,4 dichlorobenzoic acid

sodium methylate
124-41-4

sodium methylate

A

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

B

2-chloro-4-hydroxybenzoic acid
56363-84-9

2-chloro-4-hydroxybenzoic acid

Conditions
ConditionsYield
at 183℃;
2,4 dichlorobenzoic acid
50-84-0

2,4 dichlorobenzoic acid

A

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

B

2-chloro-4-hydroxybenzoic acid
56363-84-9

2-chloro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With methanol; sodium methylate at 183℃;
2-amino-4-chlorobenzamide
5900-59-4

2-amino-4-chlorobenzamide

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With cis-nitrous acid
2-methoxy-4-chlorobenzoic acid
57479-70-6

2-methoxy-4-chlorobenzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With hydrogen iodide
4-Aminosalicylic acid
65-49-6

4-Aminosalicylic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

phosgene
75-44-5

phosgene

3-monochlorophenol
108-43-0

3-monochlorophenol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Yield given. Multistep reaction;
N-(4-chloro-2-hydroxybenzoyl)-2-methylalanine
129973-06-4

N-(4-chloro-2-hydroxybenzoyl)-2-methylalanine

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With sulfuric acid 1) reflux, 1.5h, 2) 3 deg C, 24h; Yield given;
dipotassium 4-chlorosalicyl sulphate
87962-96-7

dipotassium 4-chlorosalicyl sulphate

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With HCl-chloroacetate; potassium chloride at 70℃; Rate constant;
sulfuric acid
7664-93-9

sulfuric acid

acetic acid
64-19-7

acetic acid

para-chlorobenzoic acid
74-11-3

para-chlorobenzoic acid

platinum anode

platinum anode

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
at 60 - 70℃; bei der elektrolytischen Oxydation;
3-monochlorophenol
108-43-0

3-monochlorophenol

carbon dioxide
124-38-9

carbon dioxide

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With potassium carbonate at 210℃; under 36775.4 Torr;
carbon dioxide
124-38-9

carbon dioxide

3-chloro-phenol sodium

3-chloro-phenol sodium

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
at 140 - 150℃; im Autoklaven; Behandeln mit Salzsaeure;
7-chloro-2.3-dimethyl-chromone

7-chloro-2.3-dimethyl-chromone

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With sodium hydroxide
diazotized 4-amino-2-hydroxy-benzoic acid

diazotized 4-amino-2-hydroxy-benzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With hydrogenchloride; copper(l) chloride
diazotized 4-chloro-2-amino-benzoic acid

diazotized 4-chloro-2-amino-benzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-chloro-2-hydroxy-3-trimethylsilanyl-benzoic acid

4-chloro-2-hydroxy-3-trimethylsilanyl-benzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In N,N-dimethyl-formamide at 100℃; for 48h;0.60 g
carbon dioxide
124-38-9

carbon dioxide

1-chloro-3-(methoxymethoxy)benzene
91105-99-6

1-chloro-3-(methoxymethoxy)benzene

A

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

B

2-chloro-6-hydroxybenzoic acid
56961-31-0

2-chloro-6-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 1-chloro-3-(methoxymethoxy)benzene With n-butyllithium In tetrahydrofuran; hexane at -75℃; for 2h;
Stage #2: carbon dioxide In tetrahydrofuran; hexane
Stage #3: With hydrogenchloride In water pH=1; Title compound not separated from byproducts;
4-chloro-2-methoxymethoxy-3-trimethylsilanyl-benzoic acid

4-chloro-2-methoxymethoxy-3-trimethylsilanyl-benzoic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl / H2O / pH 1
2: 0.60 g / tetrabutylammonium fluoride trihydrate / dimethylformamide / 48 h / 100 °C
View Scheme
3-monochlorophenol
108-43-0

3-monochlorophenol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 55 percent / N-ethyldiisopropylamine / CH2Cl2 / 2 h / 25 °C
2.1: 66 percent / 2,2,6,6-tetramethylpiperidine; butyllithium / tetrahydrofuran; hexane / cooling
3.1: sec-butyllithium / tetrahydrofuran; cyclohexane / 6 h / -75 °C
3.2: tetrahydrofuran; cyclohexane
4.1: HCl / H2O / pH 1
5.1: 0.60 g / tetrabutylammonium fluoride trihydrate / dimethylformamide / 48 h / 100 °C
View Scheme
Multi-step reaction with 2 steps
1.1: 55 percent / N-ethyldiisopropylamine / CH2Cl2 / 2 h / 25 °C
2.1: butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C
2.2: tetrahydrofuran; hexane
2.3: HCl / H2O / pH 1
View Scheme
1-chloro-3-(methoxymethoxy)benzene
91105-99-6

1-chloro-3-(methoxymethoxy)benzene

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 66 percent / 2,2,6,6-tetramethylpiperidine; butyllithium / tetrahydrofuran; hexane / cooling
2.1: sec-butyllithium / tetrahydrofuran; cyclohexane / 6 h / -75 °C
2.2: tetrahydrofuran; cyclohexane
3.1: HCl / H2O / pH 1
4.1: 0.60 g / tetrabutylammonium fluoride trihydrate / dimethylformamide / 48 h / 100 °C
View Scheme
[2-chloro-6-(methoxymethoxy)phenyl]trimethylsilane
851341-60-1

[2-chloro-6-(methoxymethoxy)phenyl]trimethylsilane

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sec-butyllithium / tetrahydrofuran; cyclohexane / 6 h / -75 °C
1.2: tetrahydrofuran; cyclohexane
2.1: HCl / H2O / pH 1
3.1: 0.60 g / tetrabutylammonium fluoride trihydrate / dimethylformamide / 48 h / 100 °C
View Scheme
2-(4-chlorobenzoylamino)-2-methylpropionic acid
129973-02-0

2-(4-chlorobenzoylamino)-2-methylpropionic acid

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1) Cu(0)/O2/trimethylamine N-oxide, 2) 0.5N HCl / 1) CH3CN, 75 deg C, 4h
2: 15percent aq. H2SO4 / 1) reflux, 1.5h, 2) 3 deg C, 24h
View Scheme
4-chloro-benzoyl chloride
122-01-0

4-chloro-benzoyl chloride

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1) NaOH, 2) 5N HCl / 1) H2O, a) 12 deg C, 2.5h, b) 20 deg C, 1h, 2) 0 deg C
2: 1) Cu(0)/O2/trimethylamine N-oxide, 2) 0.5N HCl / 1) CH3CN, 75 deg C, 4h
3: 15percent aq. H2SO4 / 1) reflux, 1.5h, 2) 3 deg C, 24h
View Scheme
4-chloro-2-nitrobenzonitrile
34662-32-3

4-chloro-2-nitrobenzonitrile

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iron; diluted acetic acid / <70
2: nitrous acid
View Scheme
4-Chloro-2-nitroaniline
89-63-4

4-Chloro-2-nitroaniline

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
2: iron; diluted acetic acid / <70
3: nitrous acid
View Scheme
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

methyl iodide
74-88-4

methyl iodide

methyl 4-chloro-2-hydroxybenzoate
22717-55-1

methyl 4-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h;100%
With caesium carbonate In N,N-dimethyl-formamide at 20℃;92%
With caesium carbonate In N,N-dimethyl-formamide at 20℃;92%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

ethyl iodide
75-03-6

ethyl iodide

4-chloro-2-ethoxybenzoic acid ethyl ester
472809-12-4

4-chloro-2-ethoxybenzoic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone for 18h; Heating / reflux;100%
With potassium carbonate In N,N-dimethyl-formamide66%
With sodium hydride In N,N-dimethyl-formamide at 0 - 60℃; for 2.16667h;
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 60℃; for 2h;
methanol
67-56-1

methanol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

methyl 4-chloro-2-hydroxybenzoate
22717-55-1

methyl 4-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
With sulfuric acid for 18h; Inert atmosphere; Reflux;98%
With sulfuric acid for 18h; Reflux; Inert atmosphere;98%
With thionyl chloride for 3h; Reflux;95%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-chloro-2-hydroxybenzyl alcohol
64917-81-3

4-chloro-2-hydroxybenzyl alcohol

Conditions
ConditionsYield
With sodium tetrahydroborate; Trimethyl borate; dimethyl sulfate In tetrahydrofuran at 20℃; for 4.5h;97%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 40℃; for 4.16667h;95%
With dimethylsulfide borane complex In tetrahydrofuran at 0℃; for 16.5h; Heating / reflux;83%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-chlorobenzylamine
104-86-9

4-chlorobenzylamine

4-chloro-N-(4-chlorobenzyl)salicylamide
610320-57-5

4-chloro-N-(4-chlorobenzyl)salicylamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene for 3h; Heating;95%
With phosphorus trichloride In chlorobenzene Reflux;
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

methyl iodide
74-88-4

methyl iodide

methyl 2-methoxy-4-chlorobenzoate
78955-90-5

methyl 2-methoxy-4-chlorobenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 18h;95%
In N-methyl-acetamide77.4%
With potassium carbonate In acetone at 20℃; Reflux; Darkness;
dichloromethane
75-09-2

dichloromethane

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

7-chloro-4H-benzo[d][1,3]dioxin-4-one
1591954-03-8

7-chloro-4H-benzo[d][1,3]dioxin-4-one

Conditions
ConditionsYield
With potassium phosphate tribasic trihydrate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 6h; Green chemistry;95%
3,5-dihydroxyphenol
108-73-6

3,5-dihydroxyphenol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

6-chloro-1,3-dihydroxy-9H-xanthen-9-one
61101-89-1

6-chloro-1,3-dihydroxy-9H-xanthen-9-one

Conditions
ConditionsYield
With methanesulfonic acid; phosphorus pentoxide for 0.25h; Heating;93%
With Eaton’s reagent at 90℃; for 0.333333h;41%
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

C9H6ClF3O3

C9H6ClF3O3

Conditions
ConditionsYield
With thionyl chloride for 6h; Inert atmosphere; Reflux;91%
C20H15N2PS2
89430-08-0

C20H15N2PS2

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

7-chloro-2-thioxo-2,3-dihydro-4H-1,3-benzoxazin-4-one

7-chloro-2-thioxo-2,3-dihydro-4H-1,3-benzoxazin-4-one

Conditions
ConditionsYield
In dichloromethane90%
1,1-bis(4-fluorophenyl)-3-phenylprop-2-yn-1-ol
1000679-96-8

1,1-bis(4-fluorophenyl)-3-phenylprop-2-yn-1-ol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

2-[2,2-di(4-fluorophenyl)ethenyl]-2-phenyl-7-chloro-2H,4H-1,3-benzodioxin-4-one

2-[2,2-di(4-fluorophenyl)ethenyl]-2-phenyl-7-chloro-2H,4H-1,3-benzodioxin-4-one

Conditions
ConditionsYield
In toluene for 10h; Reflux;89%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

methyl 4-chloro-2-hydroxybenzoate
22717-55-1

methyl 4-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
With sulfuric acid In methanol88.6%
With sulfuric acid In methanol88.6%
With sulfuric acid In methanol
With hydrogenchloride In methanol
With sulfuric acid In methanol; diethyl ether; benzene
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-phenyl-3-butyne-2-one
1817-57-8

4-phenyl-3-butyne-2-one

7-chloro-2-(2-oxopropyl)-2-phenyl-4H-benzo[d][1,3]dioxin-4-one

7-chloro-2-(2-oxopropyl)-2-phenyl-4H-benzo[d][1,3]dioxin-4-one

Conditions
ConditionsYield
With morpholine In dichloromethane at 20℃; for 24h; Michael Addition;87%
4-methylphenylglyoxal
1075-47-4

4-methylphenylglyoxal

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

isooctyl isocyanoacetate

isooctyl isocyanoacetate

benzylamine
100-46-9

benzylamine

C34H41ClN2O6

C34H41ClN2O6

Conditions
ConditionsYield
Stage #1: 4-methylphenylglyoxal; 4-chlorosalicylic acid; isooctyl isocyanoacetate; benzylamine In methanol at 30℃; for 24h;
Stage #2: With sodium tetrahydroborate In methanol at 30℃; for 1h;
86%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

acetic anhydride
108-24-7

acetic anhydride

2-carboxy-5-chlorophenyl acetate
17336-08-2

2-carboxy-5-chlorophenyl acetate

Conditions
ConditionsYield
Stage #1: 4-chlorosalicylic acid; acetic anhydride With triethylamine In tetrahydrofuran at 20℃; for 19h;
Stage #2: With hydrogenchloride In water
85%
With sulfuric acid
With phosphoric acid
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

4-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide
175903-29-4

4-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene for 0.333333h; Reflux; Microwave irradiation;85%
With phosphorus trichloride Microwave irradiation;
With phosphorus trichloride In chlorobenzene Microwave irradiation;
With phosphorus trichloride In chlorobenzene for 0.416667h; Microwave irradiation;
1,1,3-triphenylprop-2-yn-1-ol
1522-13-0

1,1,3-triphenylprop-2-yn-1-ol

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

2-2,2-(diphenylethenyl)-2-phenyl-7-chloro-2H,4H-1,3-benzodioxin-4-one

2-2,2-(diphenylethenyl)-2-phenyl-7-chloro-2H,4H-1,3-benzodioxin-4-one

Conditions
ConditionsYield
In toluene for 10h; Reflux;85%
tryptamine
61-54-1

tryptamine

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-chloro-2-hydroxy-N-[2-(1H-indol-3-yl)ethyl]benzamide

4-chloro-2-hydroxy-N-[2-(1H-indol-3-yl)ethyl]benzamide

Conditions
ConditionsYield
Stage #1: 4-chlorosalicylic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: tryptamine In acetone at 20℃; for 24h;
84.53%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

3-hydroxy-4'-methyl-biphenyl-4-carboxylic acid

3-hydroxy-4'-methyl-biphenyl-4-carboxylic acid

Conditions
ConditionsYield
With potassium phosphate; 2-(dicyclohexylphosphino)biphenyl based D-gluconamide; palladium diacetate In water at 80℃; for 16h;84%
4-bromophenylglyoxal
5195-29-9

4-bromophenylglyoxal

hexan-1-amine
111-26-2

hexan-1-amine

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

n-heptyl isocyanoacetate

n-heptyl isocyanoacetate

C31H42BrClN2O6

C31H42BrClN2O6

Conditions
ConditionsYield
Stage #1: 4-bromophenylglyoxal; hexan-1-amine; 4-chlorosalicylic acid; n-heptyl isocyanoacetate In methanol at 30℃; for 24h;
Stage #2: With sodium tetrahydroborate In methanol at 30℃; for 1h;
83%
2-Bromo-5-trifluoromethylaniline
454-79-5

2-Bromo-5-trifluoromethylaniline

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

C14H8BrClF3NO2

C14H8BrClF3NO2

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene at 150℃; for 2h;82%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

3,5-Bis-(trifluoromethyl)aniline
328-74-5

3,5-Bis-(trifluoromethyl)aniline

N-(3,5-bis(trifluoromethyl)phenyl)-4-chloro-2-hydroxybenzamide

N-(3,5-bis(trifluoromethyl)phenyl)-4-chloro-2-hydroxybenzamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene Microwave irradiation;82%
55.8%
With pyridine; phosphorus trichloride In toluene Inert atmosphere; Reflux;52%
With phosphorus trichloride In chlorobenzene for 0.416667h; Microwave irradiation;
With phosphorus trichloride In 5,5-dimethyl-1,3-cyclohexadiene for 5h; Reflux;
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzo[d]thiazol-2-yl)-5-chlorophenol
90481-40-6

2-(benzo[d]thiazol-2-yl)-5-chlorophenol

Conditions
ConditionsYield
With phosphorus trichloride In toluene for 4h; Heating;81%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

3,4-dichlorobenzyl amine
102-49-8

3,4-dichlorobenzyl amine

4-chloro-N-(3,4-dichlorobenzyl)salicylamide
610320-85-9

4-chloro-N-(3,4-dichlorobenzyl)salicylamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene for 3h; Heating;80%
With phosphorus trichloride In chlorobenzene Reflux;
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

3,5-Dichloroaniline
626-43-7

3,5-Dichloroaniline

4-chloro-N-(3,5-dichlorophenyl)-2-hydroxybenzamide

4-chloro-N-(3,5-dichlorophenyl)-2-hydroxybenzamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene for 0.416667h; Microwave irradiation;80%
57.2%
3-bromo-1,1,1-trifluoroacetone
431-35-6

3-bromo-1,1,1-trifluoroacetone

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

C10H4ClF3O3

C10H4ClF3O3

Conditions
ConditionsYield
With dipotassium hydrogenphosphate; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; 1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; silver(I) acetate; XPhos In 2,2,2-trifluoroethanol at 140℃; for 24h; Sealed tube;80%
With dipotassium hydrogenphosphate; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) acetate In 2,2,2-trifluoroethanol at 140℃; for 24h;76%
4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

3-bromoaniline
591-19-5

3-bromoaniline

N-(3-bromophenyl)-4-chloro-2-hydroxybenzamide
175903-18-1

N-(3-bromophenyl)-4-chloro-2-hydroxybenzamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene for 0.333333h; Reflux; Microwave irradiation;79%
With phosphorus trichloride In chlorobenzene Microwave irradiation;
With phosphorus trichloride In chlorobenzene for 0.333333h; Microwave irradiation;
5-chlorotryptamine
3764-94-1

5-chlorotryptamine

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-chloro-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-2-hydroxybenzamide

4-chloro-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-2-hydroxybenzamide

Conditions
ConditionsYield
Stage #1: 4-chlorosalicylic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-chlorotryptamine In acetone at 20℃; for 24h;
78.47%

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