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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity Ethyl 2-phenylacetoacetate

Cas:5413-05-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical

ETHYL 2-PHENYLACETOACETATE/5413-05-8

Cas:5413-05-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

High purity Ethyl 2-phenylacetoacetate CAS NO.5413-05-8

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $6.5 / 6.6

Type:Trading Company

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Saiwante (shanghai) New Material Technology Co., Ltd.

Factory Price CAS 5413-05-8 Door to Door Delivery Safety and Fastly Product name ETHYL 2-PHENYLACETOACETATE CAS number 5413-05-8 Purity 99% Appearance Powder Packing: 1. Inner double plast

Factory Price CAS 5413-05-8 Door to Door Delivery Safety and Fastly

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $8.0 / 11.0

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Ethyl 2-phenylacetoacetate Manufacturer/High quality/Best price/In stock

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

High quality ETHYL 2-PHENYLACETOACETATE CAS 5413-05-8 Application:High quality ETHYL 2-PHENYLACETOACETATE CAS 5413-05-8

High quality ETHYL 2-PHENYLACETOACETATE CAS 5413-05-8

Cas:5413-05-8

Min.Order:0

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 5413-05-8 Benzeneacetic acid, a-acetyl-, ethyl ester

Cas:5413-05-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Ethyl 2-phenylacetoacetate

Cas:5413-05-8

Min.Order:100 Gram

FOB Price: $10.0

Type:Manufacturers

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Ality Chemical Corporation

We are manufacturer of this product. If you are looking for the material's manufacturer or supplier in China, Ality Group is your best choice. Specifications of our Ethyl 2-phenylacetoacetate CAS 5413-05-8: Items

Factory Supply Ethyl 2-phenylacetoacetate

Cas:5413-05-8

Min.Order:1 Gram

FOB Price: $1.0 / 3.0

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Ethyl 2-phenylacetoacetate 5413-05-8 ethyl 3-oxo-2-phenylbutanoate

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 30.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5413-05-8 with competitive price

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Ethyl 2-phenylacetoacetate

Cas:5413-05-8

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

Benzeneacetic acid, a-acetyl-, ethyl ester

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzeneacetic acid, a-acetyl-, ethyl ester 5413-05-8

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We generally use secure shipping methods that do not require you to do any customs clearance. Free shipping to your address without worrying about any customs issues. We have a professional customs clearance team to 100% guarantee the safe delivery o

TeruiOP Ethyl 2-phenylacetoacetate cas 5413-05-8 100% sefe delivery

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

ETHYL 2-PHENYLACETOACETATE/ LIDE PHARMA- Factory supply / Best price

Cas:5413-05-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanxi Ankesi Biotechnology Co., Ltd

Our Advantage 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good qual

99% purity Ethyl 2-phenylacetoacetate CAS NO.5413-05-8

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

Ethyl 3-oxo-4-phenylbutanoate

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

ETHYL 2-PHENYLACETOACETATE CAS: 5413-05-8 Specification Melting point 140-144°C/10mm Boiling point 140-144°C 10mm density 1,085 g/cm3 refractive index 1.5130 Fp 140-144°C/

Factory supply ETHYL 2-PHENYLACETOACETATE

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzeneacetic acid, a-acetyl-, ethyl ester

Cas:5413-05-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Ethyl 2-phenylacetoacetate CAS 5413-05-8

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products ETHYL 2-PHENYLACETOACETATE

Cas:5413-05-8

Min.Order:100 Gram

Negotiable

Type:Other

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Shaanxi New nine Material Technology Co., Ltd.

Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D

High purity Ethyl 2-phenylacetoacetate CAS NO.5413-05-8

Cas:5413-05-8

Min.Order:10 Gram

FOB Price: $8.0 / 10.0

Type:Trading Company

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Specif

Ethyl 2-phenylacetoacetate 5413-05-8

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Wuhan Xinhao Biotechnology Co., Ltd.

High quality with competitive price. 1. Standard bp/usp/ep/enterprise standard. 2. All purity>99%. 3. We are manufacturer and can provide high quality products with factory price. Fast and safe delivery. 1. Parcel can be sent out in 24 hours afte

High Quality Ethyl 2-phenylacetoacetate

Cas:5413-05-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Benzeneacetic acid, a-acetyl-, ethyl ester

Cas:5413-05-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to make other chemic

Benzeneacetic acid, a-acetyl-, ethyl ester

Cas:5413-05-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

high purityETHYL 2-PHENYLACETOACETATE

Cas:5413-05-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

ETHYL2-PHENYLACETOACETATE

Cas:5413-05-8

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

ETHYL 2-PHENYLACETOACETATE Chemical Properties Melting point 140-144°C/10mm Boiling point 140-144°C 10mm density 1,085 g/cm3 refractive index 1.5130 Fp 140-144°C/10mm pka 10.69±0.46(Predicted) BRN 1912655

ETHYL 2-PHENYLACETOACETATE

Cas:5413-05-8

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

Synthetic route

3-Oxo-2-phenyl-butyrimidic acid ethyl ester
687981-26-6

3-Oxo-2-phenyl-butyrimidic acid ethyl ester

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 40℃; for 1.5h;97%
With sulfuric acid; water In ethyl acetate at 20 - 50℃; for 4.5h;
iodobenzene
591-50-4

iodobenzene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

B

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

Conditions
ConditionsYield
With potassium carbonate; copper(l) iodide In dimethyl sulfoxide at 80℃; for 20h;A 9%
B 89%
With potassium phosphate; copper(l) iodide In dimethyl sulfoxide at 80℃; for 20h;A 26%
B 20%
iodobenzene
591-50-4

iodobenzene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With copper(l) iodide; caesium carbonate In 1,4-dioxane at 70℃; for 25h;78%
ethyl 2-diazo-3-hydroxy-3-phenylbutanoate
27262-63-1

ethyl 2-diazo-3-hydroxy-3-phenylbutanoate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane for 1h; Ambient temperature;75%
With tris-(dibenzylideneacetone)dipalladium(0); para-iodoanisole; diisopropylamine; XPhos In toluene at 100℃; for 48h; Inert atmosphere;57%
acetic anhydride
108-24-7

acetic anhydride

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
Stage #1: Ethyl 2-phenylethanoate With sodium hydride In tetrahydrofuran at 60℃; for 0.5h; Cooling with ice;
Stage #2: acetic anhydride In tetrahydrofuran at 0 - 20℃; for 1h;
61%
Stage #1: Ethyl 2-phenylethanoate With sodium hydride In tetrahydrofuran at 60℃; for 0.5h;
Stage #2: acetic anhydride In tetrahydrofuran at 20℃; for 1h;
51%
Stage #1: Ethyl 2-phenylethanoate With sodium hydride In tetrahydrofuran at 60℃; for 0.5h;
Stage #2: acetic anhydride In tetrahydrofuran at 20℃; for 1h; Further stages.;
51%
Stage #1: Ethyl 2-phenylethanoate With sodium hydride In tetrahydrofuran at 60℃; for 0.5h; Inert atmosphere;
Stage #2: acetic anhydride In tetrahydrofuran at 0℃;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

diphenyliodonium hexafluorophosphate
58109-40-3

diphenyliodonium hexafluorophosphate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;60%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

triphenylbismuth carbonate
47252-14-2

triphenylbismuth carbonate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
In dichloromethane at 40℃; for 20h;59%
59%
diphenyliodonium tetrafluoroborate

diphenyliodonium tetrafluoroborate

ethyl acetoacetate
141-97-9

ethyl acetoacetate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
Stage #1: ethyl acetoacetate With potassium tert-butylate In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: diphenyliodonium tetrafluoroborate In N,N-dimethyl-formamide at 0 - 20℃; for 18h; Reagent/catalyst; Inert atmosphere;
53%
(6-chloropyridin-3-yl)(phenyl)iodonium trifluoromethanesulfonate

(6-chloropyridin-3-yl)(phenyl)iodonium trifluoromethanesulfonate

ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

B

ethyl 2-(6-chloropyridin-3-yl)-3-oxobutanoate

ethyl 2-(6-chloropyridin-3-yl)-3-oxobutanoate

Conditions
ConditionsYield
Stage #1: ethyl acetoacetate With potassium tert-butylate In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: (6-chloropyridin-3-yl)(phenyl)iodonium trifluoromethanesulfonate In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere; chemoselective reaction;
A 12%
B 50%
Diphenyliodonium triflate
66003-76-7

Diphenyliodonium triflate

ethyl acetoacetate
141-97-9

ethyl acetoacetate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;45%
bromobenzene
108-86-1

bromobenzene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With potassium phosphate; palladium diacetate; di-tert-butyl (2'-methyl-[1,1'-biphenyl]-2-yl)phosphine In toluene Reflux;25%
With potassium phosphate; palladium diacetate; di-tert-butyl (2'-methyl-[1,1'-biphenyl]-2-yl)phosphine In toluene at 90℃; for 16h;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

diphenyliodonium bromide
1483-73-4

diphenyliodonium bromide

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;10%
2-phenylmalonic acid monoethyl ester
17097-90-4

2-phenylmalonic acid monoethyl ester

isopropylmagnesium bromide
920-39-8

isopropylmagnesium bromide

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With tetrahydrofuran anschliessend mit Acetylchlorid Umsetzen;
ethyl acetate
141-78-6

ethyl acetate

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With diethyl ether; sodium
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With diethyl ether; ammonia; sodium amide Erwaermen des Reaktionsprodukts mit Phenylacetat in Aether;
With lithium diisopropyl amide In tetrahydrofuran; heptane-tetrahydrofuranethylbenzene; water; ethyl acetate
ethanol
64-17-5

ethanol

1-phenyl-1-cyanopropan-2-one
4468-48-8

1-phenyl-1-cyanopropan-2-one

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With hydrogenchloride Loesen des salzsauren Iminoaethers in Alkohol und anschl. Verduennen mit Wasser;
1-phenyl-1-cyanopropan-2-one
4468-48-8

1-phenyl-1-cyanopropan-2-one

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
ueber den Iminoaether;
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

acetophenone
98-86-2

acetophenone

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
(i) nBuLi, (ii) HCl; Multistep reaction;
ethyl 2-diazo-3-hydroxy-3-phenylbutanoate
27262-63-1

ethyl 2-diazo-3-hydroxy-3-phenylbutanoate

A

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

B

acetophenone
98-86-2

acetophenone

C

ethyl 2-benzoylpropionate
10488-87-6

ethyl 2-benzoylpropionate

Conditions
ConditionsYield
palladium dichloride In benzene Product distribution; Heating; other temp., other times, other solv., other matal salts as catalysts;
ethyl 2-diazo-3-hydroxy-3-phenylbutanoate
27262-63-1

ethyl 2-diazo-3-hydroxy-3-phenylbutanoate

A

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

B

ethyl 2-benzoylpropionate
10488-87-6

ethyl 2-benzoylpropionate

Conditions
ConditionsYield
palladium dichloride In benzene Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
ethyl 4-bromo-3-oxo-2-phenylbutanoate
408320-75-2

ethyl 4-bromo-3-oxo-2-phenylbutanoate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With acetic acid; zinc In diethyl ether
ethanol
64-17-5

ethanol

2-diazo-1-phenylbutane-1,3-dione
2009-96-3

2-diazo-1-phenylbutane-1,3-dione

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
In 1,4-dioxane Heating;
diethyl ether
60-29-7

diethyl ether

Phenyl acetate
122-79-2

Phenyl acetate

sodium phenylacetic acid ethyl ester

sodium phenylacetic acid ethyl ester

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

acetyl chloride
75-36-5

acetyl chloride

bromomercurio-phenyl-acetic acid ethyl ester

bromomercurio-phenyl-acetic acid ethyl ester

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
With toluene
acetyl chloride
75-36-5

acetyl chloride

potassium phenylacetic acid ester

potassium phenylacetic acid ester

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
at 20℃;
bromobenzene
108-86-1

bromobenzene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

B

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

Conditions
ConditionsYield
With potassium phosphate; di-tert-butyl (2'-methyl-[1,1'-biphenyl]-2-yl)phosphine; palladium diacetate In toluene at 90℃; for 16h; Product distribution; Further Variations:; Catalysts; Reaction partners; Reagents;A n/a
B 93 % Chromat.
acetophenone
98-86-2

acetophenone

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 47 percent / diispropylamine, n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C
2: PdCl2 / benzene / Heating
View Scheme
phenylacetonitrile
140-29-4

phenylacetonitrile

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium ethylate
2: hydrogen chloride / Loesen des salzsauren Iminoaethers in Alkohol und anschl. Verduennen mit Wasser
View Scheme
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

ethyl (Z)-2-phenyl-3-(trifluoromethylsulfonyloxy)but-2-enoate
1037590-38-7

ethyl (Z)-2-phenyl-3-(trifluoromethylsulfonyloxy)but-2-enoate

Conditions
ConditionsYield
Stage #1: ethyl 2-phenylacetoacetate With lithium hydroxide In water; toluene at 5 - 10℃; for 0.0833333h;
Stage #2: trifluoromethylsulfonic anhydride In water; toluene at 5 - 15℃; Schotten-Baumann type reaction; optical yield given as %de; stereoselective reaction;
98%
2-aminopyridine
504-29-0

2-aminopyridine

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

2-methyl-3-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

2-methyl-3-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Conditions
ConditionsYield
With bismuth(III) chloride at 100℃; for 3h; Green chemistry;96%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

3-methyl-4-phenyl-1H-pyrazol-5-ol
64754-67-2

3-methyl-4-phenyl-1H-pyrazol-5-ol

Conditions
ConditionsYield
With acetic acid; hydrazine for 1h; Heating / reflux;92%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

C15H19NO4

C15H19NO4

Conditions
ConditionsYield
With tert.-butylhydroperoxide at 70℃; for 0.5h;90%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

3-amino-5-methoxyphenol
162155-27-3

3-amino-5-methoxyphenol

5-hydroxy-7-methoxy-4-methyl-3-phenylquinolin-2(1H)-one
1392191-15-9

5-hydroxy-7-methoxy-4-methyl-3-phenylquinolin-2(1H)-one

Conditions
ConditionsYield
In chlorobenzene at 160℃; for 0.5h; Microwave irradiation;89%
In chlorobenzene at 160℃; Microwave irradiation;89%
1H-benzimidazol-2-acetonitrile
4414-88-4

1H-benzimidazol-2-acetonitrile

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

3-methyl-1-oxo-2-phenyl-1H,5H-pyrido[1,2-a]benzimidazole-4-carbonitrile
577775-45-2

3-methyl-1-oxo-2-phenyl-1H,5H-pyrido[1,2-a]benzimidazole-4-carbonitrile

Conditions
ConditionsYield
With ammonium acetate at 140 - 150℃; for 0.666667h;85%
With ammonium acetate at 140 - 150℃;85%
With ammonium acetate at 150℃; neat (no solvent);81%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

(Z)-ethyl 3-amino-2-phenylbut-2-enoate
1160169-26-5

(Z)-ethyl 3-amino-2-phenylbut-2-enoate

Conditions
ConditionsYield
With ammonium formate In ethanol Molecular sieve; Reflux;85%
N-formyldiethylamine
617-84-5

N-formyldiethylamine

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

C17H23NO4

C17H23NO4

Conditions
ConditionsYield
With tert.-butylhydroperoxide at 70℃; for 0.5h;83%
Isopropenyl acetate
108-22-5

Isopropenyl acetate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

(Z)-ethyl 3-acetoxy-2-phenylbut-2-enoate

(Z)-ethyl 3-acetoxy-2-phenylbut-2-enoate

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 130℃; for 18h; Inert atmosphere;81%
[7-methyl-2-(3H-imidazo[4,5-b]pyridine)-2-yl]acetonitrile
577777-13-0

[7-methyl-2-(3H-imidazo[4,5-b]pyridine)-2-yl]acetonitrile

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

4,7-dimethyl-9-oxo-8-phenyldipyrido[1,2-a;3',2'-d]imidazole-6-carbonitrile
577777-14-1

4,7-dimethyl-9-oxo-8-phenyldipyrido[1,2-a;3',2'-d]imidazole-6-carbonitrile

Conditions
ConditionsYield
With ammonium acetate at 140 - 150℃; for 1h;80%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

recorcinol
108-46-3

recorcinol

7-hydroxy-4-methyl-3-phenyl-chromen-2-one
2555-23-9

7-hydroxy-4-methyl-3-phenyl-chromen-2-one

Conditions
ConditionsYield
With sulfuric acid at 0 - 20℃; Pechmann Condensation;78%
With sulfuric acid
With ethanol; phosphorus pentoxide
With sulfuric acid at 100℃;
pyrid-2-ylhydrazine
4930-98-7

pyrid-2-ylhydrazine

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

5-methyl-4-phenyl-2-(pyridin-2-yl)-1H-pyrazol-3(2H)-one
101800-02-6

5-methyl-4-phenyl-2-(pyridin-2-yl)-1H-pyrazol-3(2H)-one

Conditions
ConditionsYield
With acetic acid for 1h; Heating / reflux;78%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

ethyl 4-bromo-3-oxo-2-phenylbutanoate
408320-75-2

ethyl 4-bromo-3-oxo-2-phenylbutanoate

Conditions
ConditionsYield
With bromine In chloroform at 25℃; for 1h;78%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

urethane
51-79-6

urethane

4-methyl-5-(phenyl)-2H-1,3-oxazine-2,6(3H)-dione
106013-88-1

4-methyl-5-(phenyl)-2H-1,3-oxazine-2,6(3H)-dione

Conditions
ConditionsYield
With trichlorophosphate at 95℃; for 1.75h;76%
With trichlorophosphate at 90℃; for 2.5h;70%
With trichlorophosphate at 90℃;
ethyl 2-cyanomethyl-1H-benzimidazole-4-carboxylate
577776-85-3

ethyl 2-cyanomethyl-1H-benzimidazole-4-carboxylate

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

ethyl 4-cyano-3-methyl-1-oxo-2-phenyl-1H,5H-pyrido[1,2-a]benzimidazole-6-carboxylate
577776-86-4

ethyl 4-cyano-3-methyl-1-oxo-2-phenyl-1H,5H-pyrido[1,2-a]benzimidazole-6-carboxylate

Conditions
ConditionsYield
With ammonium acetate at 140 - 150℃; for 0.5h;75%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

ethyl 2-phenyl-2-bromoacetate
2882-19-1

ethyl 2-phenyl-2-bromoacetate

Conditions
ConditionsYield
With aluminum oxide; sodium carbonate; copper(ll) bromide In benzene at 50℃; for 1h;74%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

2-hydroxyresorcinol
87-66-1

2-hydroxyresorcinol

7,8-dihydroxy-4-methyl-3-phenyl-coumarin
859740-03-7

7,8-dihydroxy-4-methyl-3-phenyl-coumarin

Conditions
ConditionsYield
With sulfuric acid at 0 - 20℃; Pechmann Condensation;72%
With sulfuric acid
With phosphoric acid
(4-tert-butyl-1H-imidazol-2-yl)acetonitrile
863399-52-4

(4-tert-butyl-1H-imidazol-2-yl)acetonitrile

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

2-tert-butyl-7-methyl-5-oxo-6-phenyl-1,5-dihydroimidazo[1,2-a]pyridine-8-carbonitrile

2-tert-butyl-7-methyl-5-oxo-6-phenyl-1,5-dihydroimidazo[1,2-a]pyridine-8-carbonitrile

Conditions
ConditionsYield
With ammonium acetate at 140℃; for 6h;71%
With ammonium acetate at 150℃; for 3.5h;33%
[5-(pyridin-4-yl)-2H-[1,2,4]triazol-3-yl]-acetonitrile
59282-73-4

[5-(pyridin-4-yl)-2H-[1,2,4]triazol-3-yl]-acetonitrile

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

7-methyl-5-oxo-6-phenyl-2-(pyridin-4-yl)-1,5-dihydro-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile

7-methyl-5-oxo-6-phenyl-2-(pyridin-4-yl)-1,5-dihydro-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile

Conditions
ConditionsYield
With ammonium acetate at 150℃; for 3h;69%
pyrid-2-ylhydrazine
4930-98-7

pyrid-2-ylhydrazine

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

3-methyl-4-phenyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol
140398-47-6

3-methyl-4-phenyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol

Conditions
ConditionsYield
With acetic acid at 130℃; for 0.0833333h; Microwave irradiation; regioselective reaction;69%
With acetic acid Reflux;
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

aniline
62-53-3

aniline

2-methyl-3-phenylhydroquinolin-4-one

2-methyl-3-phenylhydroquinolin-4-one

Conditions
ConditionsYield
Stage #1: ethyl 2-phenylacetoacetate; aniline With acetic acid In benzene at 100℃; Conrad-Limpach reaction;
Stage #2: In diphenylether; benzene for 0.25h; Conrad-Limpach reaction; Reflux;
63%
(4-methyl-1H-imidazol-2-yl)acetonitrile
863399-39-7

(4-methyl-1H-imidazol-2-yl)acetonitrile

ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

2,7-dimethyl-5-oxo-6-phenyl-1,5-dihydroimidazo[1,2-a]pyridine-8-carbonitrile

2,7-dimethyl-5-oxo-6-phenyl-1,5-dihydroimidazo[1,2-a]pyridine-8-carbonitrile

Conditions
ConditionsYield
With ammonium acetate at 150℃; for 3.5h;61%
at 140℃; for 3h;61%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

aniline
62-53-3

aniline

(Z)-2-phenyl-3-(phenylamino)but-2-enoic acid ethyl ester

(Z)-2-phenyl-3-(phenylamino)but-2-enoic acid ethyl ester

Conditions
ConditionsYield
With acetic acid In toluene Heating;60%
ethyl 2-phenylacetoacetate
5413-05-8

ethyl 2-phenylacetoacetate

4-chloro-m-anisidine
13726-14-2

4-chloro-m-anisidine

6-chloro-7-methoxy-2-methyl-3-phenylquinolin-4(1H)-one
1248347-00-3

6-chloro-7-methoxy-2-methyl-3-phenylquinolin-4(1H)-one

Conditions
ConditionsYield
Stage #1: ethyl 2-phenylacetoacetate; 4-chloro-m-anisidine With acetic acid In benzene Conrad-Limpach Synthesis; Inert atmosphere; Reflux; Dean-Stark;
Stage #2: In toluene at 260℃; for 0.05h; Conrad-Limpach Synthesis; Inert atmosphere; Microwave irradiation;
60%
Stage #1: ethyl 2-phenylacetoacetate; 4-chloro-m-anisidine With acetic acid In benzene for 18h; Conrad-Limpach Synthesis; Reflux;
Stage #2: In diphenylether; benzene for 0.2h; Conrad-Limpach Synthesis; Reflux;

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