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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-Hydroxy-6-methylbenzoic acid Manufacturer/High quality/Best price/In stock

Cas:567-61-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2-Hydroxy-6-methylbenzoic acid 567-61-3

Cas:567-61-3

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

6-Methylsalicylic acid 567-61-3

Cas:567-61-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:1 Kilogram

FOB Price: $85.0 / 96.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Hydroxy-6-methylbenzoic acid CAS:567-61-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

2-Hydroxy-6-methylbenzoic acid CAS:567-61-3

Cas:567-61-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price & quick delivery Appearance:Brown solid white to nitrogen Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Use

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2-Hydroxy-6-methylbenzoic acid Synonyms: 2-Hydroxy-6-methylbenzoic acid ,97%;6-Methylsalicylic acid, 2-Carboxy-3-hydroxytoluene, 2-Carboxy-3-methylphenol;2,6-cresoticacid;6-ms;6-msa;2-HYDROXY-6-METHYLBENZOIC ACID;6-METHYLSALICYLIC

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

6-Methylsalicylic acid cas no. 567-61-3 98%

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

high purity, manufacturer Application:Intermediate

2-Hydroxy-6-Methylbenzoicacid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2,2-Difluoro-5-(hydroxymethyl)-1,3-benzodioxole

Cas:567-61-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd a comprehensive enterprise, is located in High-Tech Science Park,Changsha,Chia . Specializing in R&D, manufacture and marketing, we provide a wide range of products and the most professional services to meet the

7-Bromo-6-chloro-4-quinazolinone

Cas:567-61-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city?in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api,?intermediat

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

6-Methylsalicylic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

2-Hydroxy-6-methylbenzoic acid CAS No.567-61-3

Cas:567-61-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

2-Hydroxy-6-methylbenzoic acid cas 567-61-3Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-Hydroxy-6-methylbenzoic acid cas 567-61-3

Cas:567-61-3

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

2-hydroxy-6-methylbenzoicacid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

567-61-3 Application:intermediate

Benzoic acid, 2-hydroxy-6-methyl-

Cas:567-61-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:10G/bottle 1kg/tin 5kg/tin 25kg/carton Application:1. Chemical raw materials 2. Used as an analytical reage

2-Hydroxy-6-methylbenzoic acid

Cas:567-61-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-methoxy-6-methyl-benzoic acid
6161-65-5

2-methoxy-6-methyl-benzoic acid

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 2-methoxy-6-methyl-benzoic acid With boron tribromide In dichloromethane at 20℃; for 14 - 20h;
Stage #2: With hydrogenchloride In dichloromethane; water Product distribution / selectivity;
100%
With piperazine In N,N-dimethyl acetamide at 150℃; for 10h; Substitution;52%
With hydrogen iodide In acetic acid
ethyl 2-hydroxy-6-methylbenzoate
6555-40-4

ethyl 2-hydroxy-6-methylbenzoate

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With sodium hydroxide at 95℃; for 2h;99%
With sodium hydroxide In ethanol Heating;95%
With sodium hydroxide for 2h; Heating;95%
2, 2, 5-trimethyl-4H-benzo[d][1,3]dioxin-4-one
438187-08-7

2, 2, 5-trimethyl-4H-benzo[d][1,3]dioxin-4-one

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With potassium hydroxide In tetrahydrofuran; water Heating;99%
With potassium hydroxide In tetrahydrofuran Heating;99%
2-amino-6-methylbenzoic acid
4389-50-8

2-amino-6-methylbenzoic acid

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 2-amino-6-methylbenzoic acid With sulfuric acid; sodium nitrite In water at 0℃; for 0.5h;
Stage #2: In water for 0.5h; Reflux;
68%
With hydrogen bromide; sodium nitrite; copper(I) bromide In water at 90℃; Reflux;65%
Diazotization;
With sulfuric acid; sodium nitrite In water at -5 - 50℃;780 mg
With sulfuric acid; sodium nitrite In water for 1h; Reflux;
tetrachloromethane
56-23-5

tetrachloromethane

3-methyl-phenol
108-39-4

3-methyl-phenol

A

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

B

4-hydroxy-2-methylbenzoic acid
578-39-2

4-hydroxy-2-methylbenzoic acid

Conditions
ConditionsYield
With copper; β‐cyclodextrin In potassium hydroxide at 80℃; for 15h;A 58%
B 29%
basic cupric o-toluate

basic cupric o-toluate

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
In nitrobenzene Heating;9%
ortho-methylbenzoic acid
118-90-1

ortho-methylbenzoic acid

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With CuCO3*Cu(OH)24%
5-methyl-chroman-2,4-dione

5-methyl-chroman-2,4-dione

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With sodium hydroxide
2,3,5-trimethyl-chromen-4-one
859085-95-3

2,3,5-trimethyl-chromen-4-one

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Ozonolyse;
2-hydroxy-6-methylbenzaldehyde
18362-36-2

2-hydroxy-6-methylbenzaldehyde

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
bei der Kalischmelze;
With potassium hydroxide at 200℃;
With sodium hydroxide; silver nitrate for 8h; Heating;
methyl 6-methylsalicylate
33528-09-5

methyl 6-methylsalicylate

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With sodium hydroxide
2-bromo-3-methylphenol
22061-78-5

2-bromo-3-methylphenol

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With n-butyllithium; diethyl ether anschliessendes Behandeln mit CO2;
hydrangenol
480-47-7

hydrangenol

A

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

B

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

Conditions
ConditionsYield
Bei der Kalischmelze;
5-bromo-2-methylbenzoic acid
79669-49-1

5-bromo-2-methylbenzoic acid

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With potassium carbonate beim Schmelzen;
3-amino-4-methyl-tropolone

3-amino-4-methyl-tropolone

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite anschliessendes Erwaermen;
oxalyl dichloride
79-37-8

oxalyl dichloride

1-methoxy-3-methyl-benzene
100-84-5

1-methoxy-3-methyl-benzene

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

ethyl 2-acetyl-3-methyl-5-oxopentanoate
3400-77-9

ethyl 2-acetyl-3-methyl-5-oxopentanoate

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
(i) (cyclization), (ii) aq. NaOH; Multistep reaction;
2,4-Dihydroxy-2-methyl-6-oxo-cyclohexanecarboxylic acid tert-butyl ester
53437-09-5

2,4-Dihydroxy-2-methyl-6-oxo-cyclohexanecarboxylic acid tert-butyl ester

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With hydrogenchloride
potassium hydroxide

potassium hydroxide

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
at 300℃;
carbon disulfide
75-15-0

carbon disulfide

aluminium trichloride
7446-70-0

aluminium trichloride

oxalyl dichloride
79-37-8

oxalyl dichloride

1-methoxy-3-methyl-benzene
100-84-5

1-methoxy-3-methyl-benzene

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
anfangs unter starker Kuehlung, und Erhitzen des Reaktionsprodukts mit HCl;
1-(2-hydroxy-6-methylphenyl)-1-propanone
51451-26-4

1-(2-hydroxy-6-methylphenyl)-1-propanone

concentrated KOH-solution

concentrated KOH-solution

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

6-oxy-2-methyl-propiophenone

6-oxy-2-methyl-propiophenone

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
With potassium hydroxide
8-methylene-2-oxabicyclo[2.2.2]octane-3,5-dione

8-methylene-2-oxabicyclo[2.2.2]octane-3,5-dione

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
at 20℃; Diels-Alder reaction;
2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one
164014-40-8

2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one

Me2CuLi

Me2CuLi

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tetrahydrofuran; diethyl ether / 1.5 h / -78 - 0 °C
1.2: 85 percent / MeI / tetrahydrofuran; diethyl ether / 0.17 h / 0 °C
2.1: 99 percent / KOH / tetrahydrofuran; H2O / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: MeLi; CuI / tetrahydrofuran; diethyl ether / -78 - 0 °C
1.2: 85 percent / tetrahydrofuran; diethyl ether / 0.17 h / 0 °C
2.1: 99 percent / aq. KOH / tetrahydrofuran / Heating
View Scheme
methyl orsellinate
3187-58-4

methyl orsellinate

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
2: Raney nickel; ethanol
3: aqueous NaOH
View Scheme
2-hydroxy-6-methyl-4-(toluene-4-sulfonyloxy)-benzoic acid methyl ester
856176-93-7

2-hydroxy-6-methyl-4-(toluene-4-sulfonyloxy)-benzoic acid methyl ester

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Raney nickel; ethanol
2: aqueous NaOH
View Scheme
3-(3-methylphenoxy)-3-oxopropanoic acid
114223-13-1

3-(3-methylphenoxy)-3-oxopropanoic acid

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: phosphorus (V)-chloride; nitrobenzene / Erwaermen des Reaktionsgemisches mit Aluminiumchlorid
2: NaOH
View Scheme
2-methyl-6-nitrobenzoic acid
13506-76-8

2-methyl-6-nitrobenzoic acid

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C
2.1: sulfuric acid; sodium nitrite / water / 0.5 h / 0 °C
2.2: 0.5 h / Reflux
View Scheme
Stage #1: 2-methyl-6-nitrobenzoic acid With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 12h;
Stage #2: With sulfuric acid; sodium nitrite In water at -5 - 50℃; for 2.5h; Inert atmosphere;
carbon dioxide
124-38-9

carbon dioxide

3-methyl-phenol
108-39-4

3-methyl-phenol

A

2-hydroxy-p-toluic acid
50-85-1

2-hydroxy-p-toluic acid

B

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 3-methyl-phenol With Mesitol; sodium hydride In mineral oil at 100℃; for 0.0833333h; Glovebox;
Stage #2: carbon dioxide In mineral oil at 185℃; under 760.051 Torr; for 2h; Overall yield = 88 %; Overall yield = 33.3 mg;
2-iodo-propane
75-30-9

2-iodo-propane

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

isopropyl 2-isopropoxy-6-methylbenzoate

isopropyl 2-isopropoxy-6-methylbenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50℃;99%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

methyl 6-methylsalicylate
33528-09-5

methyl 6-methylsalicylate

Conditions
ConditionsYield
In diethyl ether at 0℃; for 2h;95%
methanol
67-56-1

methanol

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

methyl 6-methylsalicylate
33528-09-5

methyl 6-methylsalicylate

Conditions
ConditionsYield
With sulfuric acid for 27h; Heating;90%
With sulfuric acid
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

C10H9F3O3

C10H9F3O3

Conditions
ConditionsYield
With thionyl chloride for 6h; Inert atmosphere; Reflux;90%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

acetone
67-64-1

acetone

2, 2, 5-trimethyl-4H-benzo[d][1,3]dioxin-4-one
438187-08-7

2, 2, 5-trimethyl-4H-benzo[d][1,3]dioxin-4-one

Conditions
ConditionsYield
With dmap; thionyl chloride In 1,2-dimethoxyethane for 3h;89%
With dmap; thionyl chloride In 1,2-dimethoxyethane at 20℃; for 3h; Inert atmosphere;80%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

propargyl alcohol
107-19-7

propargyl alcohol

C11H10O3

C11H10O3

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In acetonitrile for 10h; Reflux;83.6%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

di-tert-butylsilyl bis(trifluoromethanesulfonate)
85272-31-7

di-tert-butylsilyl bis(trifluoromethanesulfonate)

C16H24O3Si

C16H24O3Si

Conditions
ConditionsYield
With 2,6-dimethylpyridine In acetonitrile at 0 - 22℃; for 16h; Inert atmosphere;82%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

chloroacetonitrile
107-14-2

chloroacetonitrile

2-hydroxy-6-methyl-benzoic acid cyanomethyl ester
438187-09-8

2-hydroxy-6-methyl-benzoic acid cyanomethyl ester

Conditions
ConditionsYield
With triethylamine In acetone for 3h; Heating;80%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

2-Hydroxy-5-bromo-6-methylbenzoic acid
252955-18-3

2-Hydroxy-5-bromo-6-methylbenzoic acid

Conditions
ConditionsYield
With tetrafluoroboric acid diethyl ether; N-Bromosuccinimide In acetonitrile at -20 - 0℃;80%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

benzyl bromide
100-39-0

benzyl bromide

6-methyl-2-(phenylmethoxy)benzoic acid
118537-95-4

6-methyl-2-(phenylmethoxy)benzoic acid

Conditions
ConditionsYield
With sodium hydroxide; tetrabutylammomium bromide In dichloromethane Ambient temperature;79%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

methyl iodide
74-88-4

methyl iodide

methyl 2-methyl-6-methoxybenzoate
79383-44-1

methyl 2-methyl-6-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 16h;72.8%
With potassium carbonate In N,N-dimethyl-formamide at 70℃;4.4 g
potassium cyanide

potassium cyanide

C18H23N5O6
1295471-72-5

C18H23N5O6

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

C26H29N5O8
1295471-36-1

C26H29N5O8

Conditions
ConditionsYield
Stage #1: C18H23N5O6; 2-hydroxy-6-methylbenzoic acid With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran; dichloromethane at 20℃;
Stage #2: potassium cyanide In methanol at 20℃;
68%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

N-((2R,3R,4aS,5R,7S,8R,8aS)-7,8-dihydroxy-2,3-dimethoxy-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl)-3-(methoxymethoxy)benzamide

N-((2R,3R,4aS,5R,7S,8R,8aS)-7,8-dihydroxy-2,3-dimethoxy-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl)-3-(methoxymethoxy)benzamide

A

(2R,3R,4aR,5R,6S,8R,8aS)-6-hydroxy-2,3-dimethoxy-8-(3-(methoxymethoxy)benzamido)-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl 2-hydroxy-6-methylbenzoate

(2R,3R,4aR,5R,6S,8R,8aS)-6-hydroxy-2,3-dimethoxy-8-(3-(methoxymethoxy)benzamido)-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl 2-hydroxy-6-methylbenzoate

B

C37H43NO13

C37H43NO13

Conditions
ConditionsYield
Stage #1: 2-hydroxy-6-methylbenzoic acid With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 0.25h;
Stage #2: N-((2R,3R,4aS,5R,7S,8R,8aS)-7,8-dihydroxy-2,3-dimethoxy-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl)-3-(methoxymethoxy)benzamide In dichloromethane at 0 - 20℃; for 48h;
A 68%
B 9%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

methyllithium
917-54-4

methyllithium

2'-hydroxy-6'-methylacetophenone
41085-27-2

2'-hydroxy-6'-methylacetophenone

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether at 20 - 60℃; for 6h; Product distribution / selectivity;67%
Stage #1: 2-hydroxy-6-methylbenzoic acid; methyllithium In diethyl ether at -78 - 20℃;
Stage #2: With ammonium chloride In diethyl ether at 0℃;
51%
In tetrahydrofuran; diethyl ether for 8h; Heating; Yield given;
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

C21H31NO9

C21H31NO9

A

C29H37NO11

C29H37NO11

B

C37H43NO13

C37H43NO13

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 22℃; Inert atmosphere;A 60%
B 15%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

allyl bromide
106-95-6

allyl bromide

allyl 2-hydroxy-6-methylbenzoate

allyl 2-hydroxy-6-methylbenzoate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 50℃;56%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

ortho-toluoyl chloride
933-88-0

ortho-toluoyl chloride

2-methyl-6-{[(2-methylphenyl)carbonyl]oxy}benzoic acid
1448618-78-7

2-methyl-6-{[(2-methylphenyl)carbonyl]oxy}benzoic acid

Conditions
ConditionsYield
Stage #1: 2-hydroxy-6-methylbenzoic acid; ortho-toluoyl chloride With pyridine In dichloromethane at 0℃; for 0.5h;
Stage #2: With dmap In dichloromethane at 20℃; for 120h;
54%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

N-((2R,3R,4aS,5R,7S,8R,8aS)-7,8-dihydroxy-2,3-dimethoxy-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl)-3-(methoxymethoxy)benzamide

N-((2R,3R,4aS,5R,7S,8R,8aS)-7,8-dihydroxy-2,3-dimethoxy-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl)-3-(methoxymethoxy)benzamide

A

(2R,3R,4aR,5R,6S,8R,8aS)-6-hydroxy-2,3-dimethoxy-8-(3-(methoxymethoxy)benzamido)-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl 2-hydroxy-6-methylbenzoate

(2R,3R,4aR,5R,6S,8R,8aS)-6-hydroxy-2,3-dimethoxy-8-(3-(methoxymethoxy)benzamido)-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl 2-hydroxy-6-methylbenzoate

B

C29H37NO11

C29H37NO11

C

C37H43NO13

C37H43NO13

Conditions
ConditionsYield
Stage #1: 2-hydroxy-6-methylbenzoic acid With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 0.25h;
Stage #2: N-((2R,3R,4aS,5R,7S,8R,8aS)-7,8-dihydroxy-2,3-dimethoxy-2,3-dimethyloctahydrobenzo[b][1,4]dioxin-5-yl)-3-(methoxymethoxy)benzamide In dichloromethane at 0 - 20℃; for 48h;
A 50%
B 33%
C 6%
3,4-dihydro-β-carboline
4894-26-2

3,4-dihydro-β-carboline

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

4-methyl-7,8,13,13b-tetrahydro-5H-benzo[5',6'][1,3]oxazino[3',2':1,2]pyrido[3,4-b]indol-5-one

4-methyl-7,8,13,13b-tetrahydro-5H-benzo[5',6'][1,3]oxazino[3',2':1,2]pyrido[3,4-b]indol-5-one

Conditions
ConditionsYield
In dichloromethane at 20℃; for 12h;44.6%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

N-decanoylcysteamine
21044-09-7

N-decanoylcysteamine

C20H31NO3S

C20H31NO3S

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;35%
benzoimidazole
51-17-2

benzoimidazole

2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

1-methyl-12H-benzo[e]benzo[4,5]imidazo[2,1-b][1,3]oxazine-12-one

1-methyl-12H-benzo[e]benzo[4,5]imidazo[2,1-b][1,3]oxazine-12-one

Conditions
ConditionsYield
With pyridine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; copper(I) bromide In para-xylene at 120℃; for 36h; Schlenk technique; Green chemistry;30%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

tert-butyl (4-aminobenzyl)carbamate
94838-55-8

tert-butyl (4-aminobenzyl)carbamate

tert-butyl (4-(6-methyl-2-hydroxybenzoyl))aminobenzylcarbamate

tert-butyl (4-(6-methyl-2-hydroxybenzoyl))aminobenzylcarbamate

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran for 12h; Reflux;21%
2-hydroxy-6-methylbenzoic acid
567-61-3

2-hydroxy-6-methylbenzoic acid

(1R)-5-chloroindan-1-amine

(1R)-5-chloroindan-1-amine

C17H16ClNO2

C17H16ClNO2

Conditions
ConditionsYield
With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 12h;13%

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