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Cas:594-61-6
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inquiryProduct description: Product name 2-Hydroxyisobutyric acid CAS number 594-61-6 Assay ≥98% Appearance White to off-white crystalline powder Capacity 200mt/year Application Org
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inquiryUnique advantages for 2-hydroxyisobutyric acid Cas 594-61-6 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Powder Storage:Store below +30°C Package:25kg/drum Application:pha
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inquiryProduct Name 2-Hydroxyisobutyric acid CAS NO. 594-61-6 Formula C4H8O3 Molecular Weight 104.1 Appearance white powd
We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED
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inquiry2-Hydroxyisobutyric acid CAS:594-61-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in
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Cas:594-61-6
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Cas:594-61-6
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inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
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inquiry2-Hydroxyisobutyric acid Chemical Properties Melting point 76-80 °C(lit.) Boiling point 84 °C1.5 mm Hg(lit.) density 11412 refractive index 1.4761 (estimate) Fp 114°C/12mm storage temp. Store below +30°C. solub
Cas:594-61-6
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
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inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
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inquiry2-methyl-2-sulphatopropionamide
2-hydroxyisobutyramide
2-methyllactic acid
Conditions | Yield |
---|---|
With methanesulfonic acid; water at 130℃; under 1875.19 Torr; for 1h; Product distribution / selectivity; | 99.3% |
With nitromethane; water at 120℃; under 1875.19 Torr; for 1h; Product distribution / selectivity; | 98% |
With water; acetic acid at 130℃; under 1875.19 Torr; for 1h; Product distribution / selectivity; | 98.8% |
Conditions | Yield |
---|---|
Stage #1: 2-hydroxy-2-methylpropanenitrile With sulfuric acid; water; 1-Nitropropane at 40 - 55℃; for 0.5h; Stage #2: With water; 1-Nitropropane at 130℃; for 1h; Product distribution / selectivity; | 99.2% |
Stage #1: 2-hydroxy-2-methylpropanenitrile With nitromethane; sulfuric acid; water at 40 - 55℃; for 0.25 - 0.5h; Stage #2: With nitromethane; water at 120 - 130℃; for 0.5 - 1h; Product distribution / selectivity; | 98% |
Stage #1: 2-hydroxy-2-methylpropanenitrile With Nitroethane; sulfuric acid; water at 40 - 55℃; for 0.333333h; Stage #2: With Nitroethane; water at 120 - 130℃; for 0.75 - 1h; Product distribution / selectivity; | 98% |
2-isopropylidene-1,3-benzodithiole
A
2-methyllactic acid
B
1,2-benzenedisulfonyl dichloride
Conditions | Yield |
---|---|
With chlorine In water; tert-butyl alcohol at 0 - 5℃; for 2h; | A 77% B 95% |
Conditions | Yield |
---|---|
With potassium hydroxide In methanol; water at 20℃; | 89% |
Conditions | Yield |
---|---|
With hydrogenchloride In diethyl ether | 85% |
methanol
2-methyl-2-sulphatopropionamide
2-hydroxyisobutyramide
A
2-methyllactic acid
B
methyl 2-hydroxy-2-methylpropionate
Conditions | Yield |
---|---|
With water; acetic acid at 115℃; under 1875.19 Torr; for 1h; Product distribution / selectivity; | A 19.2% B 81.5% |
chloroform
acetone
1-benzyl-4-methyl-1,2-dihydro-pyrazol-3-one
A
poly(methacrylic acid)
B
2-methyllactic acid
C
2-chloro-2-methylpropanoic acid
D
2-(1-benzyl-4-methyl-1H-pyrazol-3-yloxy)-2-methyl-propionic acid
Conditions | Yield |
---|---|
With sodium hydroxide at 49 - 54℃; Further byproducts given; | A 0.07 mol B 0.15 mol C n/a D 77.2% |
(8aS)-3,3-dimethyl-1,4-dioxo-3,4,6,7,8,8a-hexahydro-1H-pyrrolo<2,1-c><1,4>oxazine
2-methyllactic acid
Conditions | Yield |
---|---|
With potassium hydroxide; water for 2h; Heating; | 63% |
2-methylenesuccinic acid
A
propene
B
poly(methacrylic acid)
C
2-methyllactic acid
D
carbon dioxide
E
2-oxo-propionic acid
F
acetone
Conditions | Yield |
---|---|
With barium hexa-aluminate In water at 250℃; under 15001.5 Torr; for 3h; Reagent/catalyst; Autoclave; Inert atmosphere; | A n/a B 50% C n/a D n/a E n/a F n/a |
dimethylacetylene
A
1-oxiranyl-ethanone
B
2,2,5,5-Tetramethyl-1,3-dioxolane-4-one
C
2-methyllactic acid
Conditions | Yield |
---|---|
With 3,3-dimethyldioxirane In acetone for 20h; Ambient temperature; | A n/a B 3% C 42% |
dimethylacetylene
acetone
A
1-oxiranyl-ethanone
B
2,2,5,5-Tetramethyl-1,3-dioxolane-4-one
C
2-methyllactic acid
Conditions | Yield |
---|---|
With 3,3-dimethyldioxirane for 20h; Ambient temperature; | A n/a B 3% C 42% |
With 3,3-dimethyldioxirane for 20h; Product distribution; Mechanism; Ambient temperature; | A n/a B 3% C 42% |
poly(methacrylic acid)
A
2-methyllactic acid
B
hex-1-ene-2,5-dicarboxylic acid
C
isopropyl alcohol
D
acetone
Conditions | Yield |
---|---|
With water at 230℃; for 1h; sealed tube; Further byproducts given; | A 10.4% B n/a C n/a D n/a |
tetrachloromethane
α-(α-hydroxy-isobutyryloxy)-isobutyric acid amide
A
2-methyllactic acid
B
2-hydroxyisobutyramide
Conditions | Yield |
---|---|
beim kurzem Kochen; |
Conditions | Yield |
---|---|
With nitric acid; vanadia; dinitrogen tetraoxide | |
With sodium nitrate; nitric acid; dinitrogen tetraoxide | |
With sodium hydroxide at 250℃; | |
With potassium hydroxide; water; cadmium(II) oxide |
Conditions | Yield |
---|---|
With permanganate(VII) ion |
Conditions | Yield |
---|---|
With hydrogenchloride |
Conditions | Yield |
---|---|
With calcium chloride at 95 - 97℃; |
Conditions | Yield |
---|---|
Hydrolysis; |
A
2-methyllactic acid
B
α-(hydroxy-nitroso-amino)-isobutyric acid
Conditions | Yield |
---|---|
With sodium phosphate | |
With alkali | |
With sodium borate |
Conditions | Yield |
---|---|
With nitric acid |
Conditions | Yield |
---|---|
With nitric acid |
1-bromo-3-methyl-butane-2,3-diol
2-methyllactic acid
Conditions | Yield |
---|---|
With nitric acid |
2-methyllactic acid
Conditions | Yield |
---|---|
With nitric acid |
2-bromo-2-methylpropanal
A
2-Methyl-1,2-propanediol
B
2-methyllactic acid
Conditions | Yield |
---|---|
With sodium hydroxide |
2-bromo-2-methylpropanal
2-methyllactic acid
Conditions | Yield |
---|---|
With chromic acid |
1-chloro-5-methyl-hexa-2,4-diene
A
Tetramethyl-[1,2,4,5]tetroxan
B
formic acid
C
2-methyllactic acid
Conditions | Yield |
---|---|
bei der Ozonolyse; |
1-chloro-5-methyl-hexa-2,4-diene
2-methyllactic acid
Conditions | Yield |
---|---|
With potassium permanganate; water | |
Ozonolyse; | |
With potassium permanganate; acetone |
Conditions | Yield |
---|---|
With water at 180℃; |
2-bromo-2-methylpropionic acid
A
poly(methacrylic acid)
B
2-methyllactic acid
Conditions | Yield |
---|---|
With water | |
With barium dihydroxide | |
With sodium hydroxide | |
With sodium carbonate |
3,4-Dibromo-2,5-dimethylhexa-2,4-diene
2-methyllactic acid
Conditions | Yield |
---|---|
With potassium permanganate; potassium carbonate |
2-methyllactic acid
Conditions | Yield |
---|---|
Stage #1: 2-methyllactic acid With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: 4-bromodeacetyl colchicine In N,N-dimethyl-formamide at 20℃; | 100% |
Conditions | Yield |
---|---|
With boric acid In toluene for 21h; Heating; | 99% |
With boric acid In toluene for 21h; Heating; | 99% |
2-methyllactic acid
phenethylamine
N-benzyl-2-hydroxy-2-methylpropanamide
Conditions | Yield |
---|---|
With [2-[(2,2,6,6-tetramethylpiperidin-1-yl)methyl]phenyl]boronic acid In toluene for 14h; Reagent/catalyst; Time; Solvent; Reflux; Molecular sieve; | 99% |
With dihydroxy-methyl-borane; water In toluene for 17h; Molecular sieve; Reflux; | 86% |
2-methyllactic acid
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h; | 99% |
Conditions | Yield |
---|---|
at 182℃; under 300.03 Torr; for 10.0667h; | 98.27% |
With methanesulfonic acid In cyclohexane for 60h; Reflux; | 67% |
With toluene-4-sulfonic acid In toluene for 60h; Heating; | 65% |
α-morpholine methyltriethoxysilane
2-methyllactic acid
Conditions | Yield |
---|---|
In tetrahydrofuran; diethyl ether at 20℃; | 98% |
In acetone at 20℃; | 82.5% |
Conditions | Yield |
---|---|
With propane-1,3-diyl dinitrite In tetrahydrofuran at 100℃; under 12929 Torr; for 0.5h; Temperature; | 98% |
triethoxy<1-(3-piperidinopropyl)>silane
2-methyllactic acid
Conditions | Yield |
---|---|
In tetrahydrofuran; diethyl ether at 20℃; | 97.8% |
2-methyllactic acid
N,N-dimethylaminomethyltriethoxysilane
Conditions | Yield |
---|---|
In diethyl ether at 20℃; | 96.3% |
2-methyllactic acid
Ν,Ν',Ν''-[boroxin-2,4,6-triyltris[[(1R)-3-methylbutane-1,1-diyl]imino(2-oxoethane-2,1-diyl)]]tris(2,5-dichlorobenzamide)
2,5-dichloro-N-(2-([(1R)-1-(4,4-dimethyl-5-oxo-1,3,2-dioxaborolan-2-yl)-3-methylbutyl]amino)-2-oxoethyl)benzamide
Conditions | Yield |
---|---|
In ethyl acetate at 25 - 60℃; | 96% |
2-methyllactic acid
phenyl isothiocyanate
5,5-dimethyl-3-phenyl-2,4-oxazolidinedione
Conditions | Yield |
---|---|
With silver trifluoroacetate; triethylamine In acetonitrile for 1h; Cyclization; desulfurization; Heating; | 95% |
Conditions | Yield |
---|---|
In ethanol mixt. of ZnCO3, α-hydroxycarboxylic acid, and diamine in EtOH refluxed for 4 h, allowed to cool to room temp., stirred for 1 wk; recrystd. from nethanol/isopropanol (1/1), dried under vac.; elem. anal.; | 95% |
2-methyllactic acid
2,2-dimethyl-3-(N-methyl-N-phenylamino)-2H-azirine
2-(2-hydroxy-2-methylpropanamido)-N-phenyl-N,2-dimethylpropanamide
Conditions | Yield |
---|---|
In acetonitrile at 0 - 20℃; | 95% |
2-methyllactic acid
benzyl bromide
benzyl 2-(benzyloxy)-2-methylpropanoate
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide | 94% |
Stage #1: 2-methyllactic acid With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h; Stage #2: benzyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 16h; | 47% |
Stage #1: 2-methyllactic acid With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h; Stage #2: benzyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 16h; | 47% |
2-methyllactic acid
(S)-2-hydroxy-2-methyl-1-(4-(3-methylmorpholino)-2-(4-nitrophenyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)propan-1-one
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 18h; | 94% |
2-methyllactic acid
Conditions | Yield |
---|---|
In chloroform a soln. of ligand added dropwise to a soln. of Ti complex, stirred for 15 min; evapd. (vac.), suspended in hexanes, filtered, vac.-dried overnight; elem. anal.; | 94% |
2-methyllactic acid
benzylamine
2-hydroxy-2-methyl-N-benzylpropanamide
Conditions | Yield |
---|---|
With mesocellular siliceous foam-supported boronic acid catalyst In o-xylene at 155℃; for 5h; Sealed tube; | 94% |
With dihydroxy-methyl-borane; water In toluene for 12h; Molecular sieve; Reflux; | 93% |
With [m-(1,4-diazabicyclo[2.2.2]octanekN1:kN4)]hexamethyldialuminum In toluene for 1h; Inert atmosphere; Reflux; | 60% |
2-methyllactic acid
phenylmethyl 1-piperazinecarboxylate
Benzyl 4-(2-hydroxy-2-methylpropionyl)piperazine-1-carboxylate
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 20℃; for 7h; | 92.1% |
Conditions | Yield |
---|---|
With 4-(dihydroxyboranyl)-1-methylpyridin-1-ium iodide for 15h; Heating; | 92% |
With zinc(II) chloride at 60℃; for 6h; sealed tube; | 83% |
With thionyl chloride | 81% |
Conditions | Yield |
---|---|
With salicylaldehyde at 100℃; for 36h; Inert atmosphere; chemoselective reaction; | 92% |
With copper(II) sulfate |
(S)-valinol
2-methyllactic acid
(S)-4,5-dihydro-α,α-dimethyl-4-isopropyloxazole-2-ethanol
Conditions | Yield |
---|---|
In xylene for 30h; Heating; | 92% |
In xylene for 30h; Condensation; Heating; | 31% |
In para-xylene for 28h; Heating; | 22% |
2-methyllactic acid
3-dimethylamino-2,2-dimethyl-2H-azirine
2-(2-hydroxy-2-methylpropionamido)-N,N,2-trimethylpropionamid
Conditions | Yield |
---|---|
In acetonitrile for 2h; Ambient temperature; | 92% |
Conditions | Yield |
---|---|
With tetra-(n-butyl)ammonium iodide; sodium hydrogencarbonate In dichloromethane at 20℃; for 48h; | 92% |
With N-ethyl-N,N-diisopropylamine In acetonitrile | 91% |
Stage #1: 2-methyllactic acid With sodium hydride In tetrahydrofuran; mineral oil at 5 - 20℃; for 1h; Stage #2: benzyl bromide With potassium iodide at 100℃; for 3h; Microwave irradiation; | 83% |
With tetra-(n-butyl)ammonium iodide; sodium hydrogencarbonate In dichloromethane; water at 20℃; for 60h; | 70% |
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile |
Conditions | Yield |
---|---|
With 4-(dihydroxyboranyl)-1-methylpyridin-1-ium iodide for 15h; Reflux; | 92% |
2-methyllactic acid
Conditions | Yield |
---|---|
With boric acid In toluene for 22h; Heating; | 91% |
2-methyllactic acid
ethylene glycol
2-methyl-2-propenoic acid 2-hydroxyethyl ester
Conditions | Yield |
---|---|
calcinated cesium carbonate and titan oxide on silica at 320℃; Gas phase; | 90.4% |
calcinated cesium nitrate on silica In water at 320℃; Gas phase; | 89.2% |
at 320℃; Gas phase; | 88% |
2-methyllactic acid
N-(2-adamantyl)amine
Conditions | Yield |
---|---|
With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dichloromethane at 20℃; for 2h; Condensation; | 90% |
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