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Cas:76801-85-9
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inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
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inquiryUnique advantages of Azathramycin A Cas 76801-85-9 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white powder Storage:cool dry place Package:25kg/drum Application:
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience 2. Free samples will be provided,ensure specifications and quality are right for customer 3. Customers will receive the most professional techn
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryHebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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inquiryChemical Name Azithromycin Amine CAS Number 76801-85-9 Molecular Formula C37H70N2O12 Molecular Weight
Cas:76801-85-9
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inquiry1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;
Appearance:White powder Storage:R.T Package:25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in China
Cas:76801-85-9
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:76801-85-9
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inquiry1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Azathramycin Structure: Formula: C37H70N2O12 Molecular Weight : 734.96 Synonyms: AzithromycinEPImpurityA/(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4
Cas:76801-85-9
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inquiryProduct Name: Azathramycin CAS: 76801-85-9 MF: C37H70N2O12 MW: 734.96 EINECS: 616-385-9 Mol File: 76801-85-9.mol Azathramycin Structure Azathramycin Chemical Properties Melting point 126-136°C Boiling point 815.2&plusm
Azathramycin CAS:76801-85-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
Cas:76801-85-9
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Azathramycin CAS: 76801-85-9 Specification Items Specification Result Appearance White or almost white powder White powder Purity ≥
Appearance:white or yellowish white flaky crystal Storage:Keep the sun from direct sunlight ;prevention against high temperature Package:As customer request Application:Used for research and industrial manufacture. Transportatio
Cas:76801-85-9
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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inquiryProName: Azathramycin A CAS: 76801-85-9 CasNo: 76801-85-9 Molecular Formula: C37H70N2O12 Appearance: powder Application: Pharmaceutical intermediates DeliveryTime: 7-10 working days after deposit PackAge: Inside plastic outside Port: Tianjin
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:76801-85-9
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:76801-85-9
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inquirySuperior quality Appearance:White Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Novel intermediate of Azithromycin that acts as antibiotic
Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
Azathramycin Basic information Product Name: Azathramycin Synonyms: DESMETHYL AZITHROMYCIN;AZAERYTHROMYCIN A (100 MG) (9-DEOXO-9A-AZA-9A-HOMOERYTHROMYCIN A);9-Deoxo
Cas:76801-85-9
Min.Order:1 Kilogram
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:76801-85-9
Min.Order:1 Gram
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inquiry9-deoxo-6-deoxy-6,9-epoxy-9,9a-didehydro-9a-aza-homoerythromycin A
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With potassium borohydride In methanol at 0 - 5℃; for 2h; | 93% |
Stage #1: 9-deoxo-6-deoxy-6,9-epoxy-9,9a-didehydro-9a-aza-homoerythromycin A With hydrogen; acetic acid; platinum(IV) oxide In methanol at 40 - 45℃; pH=5 - 6; Stage #2: With sodium hydroxide In water pH=11 - 12; | 85% |
Stage #1: 9-deoxo-6-deoxy-6,9-epoxy-9,9a-didehydro-9a-aza-homoerythromycin A With sodium tetrahydroborate; acetic acid pH=6 - 8; Heating; Stage #2: With gluconic acid at 8℃; Reagent/catalyst; Temperature; | 84.4% |
With sodium tetrahydroborate In methanol at 0 - 25℃; Inert atmosphere; | 77% |
With methanol; sodium tetrahydroborate at 0 - 20℃; for 24h; | 70.3% |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: C37H66N2O12 With perchloric acid; hydrogen; platinum on activated charcoal In methanol at 5 - 42℃; under 10298 Torr; for 3h; pH=5.5; Stage #2: With sodium hydroxide In water pH=12 - 12.5; | 91.5% |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: C37H66N2O12 With perchloric acid; hydrogen; platinum on activated charcoal In methanol; water at 5 - 42℃; under 10298 Torr; for 3h; pH=5.5; Stage #2: With sodium hydroxide In water pH=12 - 12.5; Product distribution / selectivity; | 86.6% |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: C37H66N2O12 With potassium borohydride; acetic acid In water at 14℃; under 22502.3 Torr; pH=7; Flow reactor; Stage #2: In ethyl acetate Stage #3: With hydrogenchloride In water; ethyl acetate for 0.05h; Pressure; Temperature; pH-value; Solvent; | 86% |
(9-E)-deoxo-9-hydroximinoerythromycin A
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: (9-E)-deoxo-9-hydroximinoerythromycin A With calcium(II) bis(trifluoromethanesulfonyl)imide; tert-butylammonium hexafluorophosphate(V) In 1,2-dimethoxyethane; 1,2-dichloro-ethane at 80℃; for 5h; Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃; for 51h; | 78% |
Multi-step reaction with 2 steps 1: p-toluenesulfonyl chloride; sodium hydrogencarbonate / acetone; water / 4 h / 0 - 20 °C 2: sodium tetrahydroborate; methanol / 24 h / 0 - 20 °C View Scheme |
erythromycin A 9-(E)-oxime
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Rearrangement; Beckmann-like rearrangement; reduction; | 45% |
Stage #1: erythromycin A 9-(E)-oxime With sodium hydrogencarbonate; p-toluenesulfonyl chloride In acetone Beckmann rearrangement; Stage #2: With hydrogen; platinum on activated charcoal In methanol under 30003 Torr; for 12h; Further stages.; | |
Multi-step reaction with 2 steps 1: methanol; water / 5 h / 5 °C / Inert atmosphere 2: sodium tetrahydroborate / methanol / 4 - 20 °C / Inert atmosphere View Scheme |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With platinum on carbon; hydrogen In methanol at 40 - 45℃; under 7500.75 Torr; for 4h; Autoclave; | 17.1% |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With Amberlite IRA-743; sulfuric acid; water for 0.5h; pH=2.8; |
C38H70N2O12
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: C38H70N2O12 With sodium tetrahydroborate; formic acid In water at 0 - 20℃; for 11h; pH=6 - 8; Stage #2: With malic acid In water Stage #3: With hydrogenchloride; sodium hydroxide more than 3 stages; |
C44H74N2O15S
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With sodium tetrahydroborate In methanol at 4 - 20℃; Beckmann rearrangement; Inert atmosphere; | 300 mg |
erythromycin
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: hydroxylamine; acetic acid / water; isopropyl alcohol / 15 h / 50 °C / Inert atmosphere 2: methanol; water / 5 h / 5 °C / Inert atmosphere 3: sodium tetrahydroborate / methanol / 4 - 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: hydroxylamine hydrochloride; triethylamine / methanol / 24 h / Reflux 2: p-toluenesulfonyl chloride; sodium hydrogencarbonate / acetone; water / 4 h / 0 - 20 °C 3: sodium tetrahydroborate; methanol / 24 h / 0 - 20 °C View Scheme |
erythromycin A oxime thiocyanate
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: erythromycin A oxime thiocyanate With sodium hydroxide In dichloromethane at 10℃; pH=9 - 11; Stage #2: With sodium tetrahydroborate In dichloromethane at 10℃; pH=0.5 - 2.5; | 57.4 g |
Multi-step reaction with 2 steps 1.1: sodium hydrogencarbonate; p-toluenesulfonyl chloride / acetone / 4 h / 0 - 10 °C 2.1: phosphoric acid; potassium borohydride / water / 8 h / 0 - 5 °C / pH 7 - 9 2.2: 3 h / 0 - 5 °C / pH 2.5 - 3 View Scheme | |
Multi-step reaction with 3 steps 1.1: sodium hydroxide / dichloromethane; water / 38 °C 2.1: sodium carbonate; p-toluenesulfonyl chloride / water / 3.2 h / 12 °C / pH Ca. 7 3.1: acetic acid; potassium borohydride / water / 14 °C / 22502.3 Torr / pH 7 / Flow reactor 3.3: 0.05 h View Scheme |
erythromycin A thiocyanate
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydroxylamine hydrochloride; triethylamine / methanol / 52 h / 30 - 55 °C / pH 6.3 - 6.7 2.1: sodium hydrogencarbonate; p-toluenesulfonyl chloride / acetone / 4 h / 0 - 10 °C 3.1: phosphoric acid; potassium borohydride / water / 8 h / 0 - 5 °C / pH 7 - 9 3.2: 3 h / 0 - 5 °C / pH 2.5 - 3 View Scheme |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: erythromycin A 6,9-imino ether With potassium borohydride; phosphoric acid In water at 0 - 5℃; for 8h; pH=7 - 9; Stage #2: With hydrogenchloride In dichloromethane; water at 0 - 5℃; for 3h; pH=2.5 - 3; Reagent/catalyst; |
benzyl chloroformate
9-Deoxo-9a-aza-9a-homoerythromycin A
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-2-O-[(phenylmethoxy)carbonyl]-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
Conditions | Yield |
---|---|
In dichloromethane at 0℃; | 100% |
Stage #1: benzyl chloroformate; 9-Deoxo-9a-aza-9a-homoerythromycin A In dichloromethane at -10 - 3℃; for 0.166667h; Stage #2: With triethylamine In dichloromethane at 3℃; for 2h; | 96.9% |
In dichloromethane at 0 - 5℃; for 1h; | 84.57% |
acrylonitrile
9-Deoxo-9a-aza-9a-homoerythromycin A
9-deoxo-9a-aza-9a-(β-cyanoethyl)-9a-homoerythromycin A
Conditions | Yield |
---|---|
at 80℃; for 24h; Michael addition; | 99% |
at 60℃; for 16h; Inert atmosphere; | 63% |
for 7h; Heating / reflux; | 41% |
formaldehyd
9-Deoxo-9a-aza-9a-homoerythromycin A
Zithromax(R)
Conditions | Yield |
---|---|
With formic acid In acetone at 30 - 55℃; for 4h; | 95% |
Stage #1: formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A With formic acid In acetone at 40 - 45℃; for 7 - 8h; Stage #2: With sodium hydroxide In water; acetone pH=11 - 11.5; | 87% |
With formic acid In water; ethyl acetate for 2h; Heating / reflux; | 77% |
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With dihydrogen peroxide In methanol; water at 0 - 20℃; for 2h; | 94.3% |
With dihydrogen peroxide In methanol; water at 0 - 20℃; for 2h; | 94.3% |
Benzyl isothiocyanate
9-Deoxo-9a-aza-9a-homoerythromycin A
C45H77N3O12S
Conditions | Yield |
---|---|
With triethylamine In acetonitrile at 60℃; for 3h; | 92% |
Conditions | Yield |
---|---|
In dichloromethane at -5 - 0℃; for 3h; | 92% |
Conditions | Yield |
---|---|
Stage #1: formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A With formic acid In acetone at 40 - 45℃; for 7 - 8h; Stage #2: With sodium hydroxide In water; acetone pH=11 - 11.5; Stage #3: With water In acetone at 20℃; for 24h; | 87% |
Stage #1: formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A With formic acid In water; acetone at 20 - 55℃; for 8h; Stage #2: With water In acetone at 38 - 40℃; for 10 - 12h; Stage #3: With water | 76.7% |
Stage #1: formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A With formic acid In chloroform; water at 20 - 55℃; for 10 - 20h; Heating / reflux; Stage #2: With water In acetone at 38 - 40℃; for 10 - 12h; | 73% |
di-tert-butyl dicarbonate
9-Deoxo-9a-aza-9a-homoerythromycin A
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-2-O-(tert-butoxycarbonyl)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-(tert-butoxycarbonyl)azacyclopentadecan-15-one
Conditions | Yield |
---|---|
With dmap In tetrahydrofuran at -5 - 5℃; for 10.5h; Solvent; Reflux; | 86.3% |
acrylic acid methyl ester
9-Deoxo-9a-aza-9a-homoerythromycin A
9-deoxo-9a-aza-9a-(γ-hydroxypropyl)-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: acrylic acid methyl ester; 9-Deoxo-9a-aza-9a-homoerythromycin A at 60℃; for 30h; Addition; hetero-Michael addition; Stage #2: With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 1h; Reduction; | 84% |
9-Deoxo-9a-aza-9a-homoerythromycin A
3-O-decladinosyl-9-deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With hydrogenchloride at 20℃; for 24h; pH=1; | 79% |
Stage #1: 9-Deoxo-9a-aza-9a-homoerythromycin A With formaldehyd; formic acid In water for 30h; Reflux; Stage #2: With sodium hydroxide In water pH=11; | 61% |
With hydrogenchloride at 20℃; for 12h; |
acrylic acid methyl ester
9-Deoxo-9a-aza-9a-homoerythromycin A
3-(9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin A) propionic acid methyl ester
Conditions | Yield |
---|---|
In chloroform at 60℃; for 48h; | 65% |
In chloroform at 60℃; for 48h; Heating / reflux; | 53.7% |
9-Deoxo-9a-aza-9a-homoerythromycin A
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10,11,13-pentahydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-15-one
Conditions | Yield |
---|---|
With hydrogenchloride In water at 50℃; for 10h; | 60.1% |
With hydrogenchloride In water at 60℃; for 64h; |
imidazole-1-carboxylic acid [2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-amide
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: imidazole-1-carboxylic acid [2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-amide; 9-Deoxo-9a-aza-9a-homoerythromycin A In N,N-dimethyl-formamide; acetonitrile at 50℃; for 2h; Acylation; Stage #2: With pyridine; hydrogen fluoride In tetrahydrofuran at 0℃; Decomposition; | 50% |
(11-carboxyundecyl)triphenylphosphonium bromide
9-Deoxo-9a-aza-9a-homoerythromycin A
{11-[(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-6-yl]-11-oxoundecyl}triphenylphosphonium chloride
Conditions | Yield |
---|---|
Stage #1: (11-carboxyundecyl)triphenylphosphonium bromide With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; diisopropyl-carbodiimide In dichloromethane at 40℃; for 0.5h; Stage #2: 9-Deoxo-9a-aza-9a-homoerythromycin A In dichloromethane at 40℃; Stage #3: In methanol | 49% |
Stage #1: (11-carboxyundecyl)triphenylphosphonium bromide With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; diisopropyl-carbodiimide In dichloromethane at 40℃; for 0.5h; Stage #2: 9-Deoxo-9a-aza-9a-homoerythromycin A In dichloromethane at 40℃; Stage #3: In methanol | 0.4 g |
Conditions | Yield |
---|---|
In toluene at 20℃; for 1h; Inert atmosphere; | 47% |
3-methoxybiphenyl-4-yl isothiocyanate
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With triethylamine In acetonitrile at 60℃; | 41% |
isopropyl isothiocyanate
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
With triethylamine In acetonitrile at 60℃; | 39% |
benzyl isothiocyanate
9-Deoxo-9a-aza-9a-homoerythromycin A
C45H77N3O13
Conditions | Yield |
---|---|
In toluene Inert atmosphere; | 35% |
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); triethylamine at 20 - 80℃; for 22h; Inert atmosphere; | 26% |
propionaldehyde
9-Deoxo-9a-aza-9a-homoerythromycin A
n-propyl azithromycin
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In N,N-dimethyl-formamide at 70℃; for 7h; Inert atmosphere; | 24% |
With 5%-palladium/activated carbon; hydrogen In ethanol at 35 - 45℃; under 750.075 - 4500.45 Torr; for 4h; Temperature; Pressure; Solvent; Reagent/catalyst; Autoclave; |
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In N,N-dimethyl-formamide Inert atmosphere; | 21% |
9-Deoxo-9a-aza-9a-homoerythromycin A
cyclohexanecarbaldehyde
C44H82N2O12
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In N,N-dimethyl-formamide Inert atmosphere; | 21% |
4-Ethynylbenzaldehyde
9-Deoxo-9a-aza-9a-homoerythromycin A
Conditions | Yield |
---|---|
Stage #1: 4-Ethynylbenzaldehyde; 9-Deoxo-9a-aza-9a-homoerythromycin A With acetic acid In N,N-dimethyl-formamide for 0.5h; Stage #2: With sodium cyanoborohydride In N,N-dimethyl-formamide at 70℃; for 7h; | 20% |
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