Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:78432-77-6
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:78432-77-6
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryProduct Name: Deacetyltaxol Synonyms: 10-DEACETYL PACLITAXEL;10-DEACETYLTAXOL;DEACETYLTAXOL;10-Desacetyl Paclitaxel;10-Desacetyltaxol;10-O-Deacetyltaxol;7-EPI-10-DEACETYL PACLITAXEL;b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR
Cas:78432-77-6
Min.Order:1 Gram
FOB Price: $8900.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:78432-77-6
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:78432-77-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
Cas:78432-77-6
Min.Order:100 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryDeacetyltaxol CAS:78432-77-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedia
Cas:78432-77-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:78432-77-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:78432-77-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:78432-77-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryChengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic
Cas:78432-77-6
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging
Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:78432-77-6
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct name: 10-Deacetyl Paclitaxel CAS No.:78432-77-6 Molecule Formula:C45H49NO13 Molecule Weight:811.87 Purity: 99% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS
Cas:78432-77-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)
Cas:78432-77-6
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in
Cas:78432-77-6
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Hangzhou ZeErRui Chemical Co., Ltd. is a leading company that is focused on developing and producing high-quality flavor ingredients used for foods, pharmaceutic, cosmetics, and daily-use goods. Our goal is to produce flavor ingredients through scien
Cas:78432-77-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in yo
Cas:78432-77-6
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryThe quality is guaranteed. If you find the product is wrong compared with COA, we promise 100% refund or change product. COA and HPLC will be shipped out with goods. You can also inform your analysis method and we will follow your analysis me
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
Cas:78432-77-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryWhy is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:Herbal extr
Cas:78432-77-6
Min.Order:0
Negotiable
Type:Trading Company
inquiryAcmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:78432-77-6
Min.Order:1 bottle
Negotiable
Type:Lab/Research institutions
inquiryhigh quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
ADVANTAGE:1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day2. The products are provided with COA, HPLC, NMR, quality assurance, pac
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In tetrahydrofuran | 96% |
taxol
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With dihydrogen peroxide; sodium hydrogencarbonate In tetrahydrofuran for 24h; Ambient temperature; | 95% |
C51H51Cl6NO17
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With acetic acid; zinc In methanol at 60℃; for 2h; | 90% |
With acetic acid; zinc In methanol |
Conditions | Yield |
---|---|
With zinc dibromide In methanol for 48h; Ambient temperature; | A 36% B 29% |
With water; scandium tris(trifluoromethanesulfonate) In methanol at 40℃; for 72h; Deacetylation; |
Conditions | Yield |
---|---|
With Enterobacter sp. CGMCC 2487 In N,N-dimethyl-formamide at 26℃; for 216h; pH=6; PBS buffer; Microbiological reaction; | A 29% B 6.9% |
7-α-glucosyloxyacetyl paclitaxel
A
10-deacetylbaccatin III
B
10-deacetylpaclitaxel
C
taxol
D
7-epipaclitaxel
Conditions | Yield |
---|---|
With Marchantia polymorpha; BG-11 medium at 25℃; Further byproducts.; | A 8% B 10% C 17% D 8% |
Conditions | Yield |
---|---|
With Glycine max; BG-11 medium at 25℃; | A 6% B 16% |
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With dihydrogen peroxide; sodium hydrogencarbonate In tetrahydrofuran Ambient temperature; |
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With sodium periodate; sulfuric acid; acetic acid; phenylhydrazine 1.) DMF, 3 h, 2.) 60 deg C, 3 h; Yield given. Multistep reaction; | |
Stage #1: 7-O-(β-xylosyl)-10-deacetyltaxol With sodium periodate; sulfuric acid In methanol; chloroform; water at 20℃; for 3h; Stage #2: With acetic acid; phenylhydrazine In methanol; water at 50℃; for 2h; | |
Stage #1: 7-O-(β-xylosyl)-10-deacetyltaxol With sodium periodate; sulfuric acid In methanol; chloroform at 20℃; for 3h; Stage #2: With acetic acid; phenylhydrazine In methanol at 50℃; for 2h; | |
With recombinant β-xylosidase Dt-xyl3 from Dictyoglomus turgidum In aq. phosphate buffer; dimethyl sulfoxide at 60℃; for 0.5h; pH=4.5; Kinetics; Catalytic behavior; Reagent/catalyst; Temperature; pH-value; Concentration; Enzymatic reaction; |
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With methanol at 20℃; Solvolysis; |
Conditions | Yield |
---|---|
With α-tocopherylpolyethyleneglycol-100 succinate; poloxamer 407; Tocopherol In water at 4℃; for 7305h; Product distribution; Further Variations:; Temperatures; time of storage; |
10-deacetyl-7,10-diTroc-baccatin III
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine / 3 h / Ambient temperature 2: 90 percent / Zn, AcOH / methanol / 2 h / 60 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine / 3 h / Ambient temperature 2: 90 percent / Zn, AcOH / methanol / 2 h / 60 °C View Scheme |
7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)docetaxel
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 75 percent / ISi(CH3)3 / acetonitrile / 0.5 h / 0 °C 2: pyridine / 3 h / Ambient temperature 3: 90 percent / Zn, AcOH / methanol / 2 h / 60 °C View Scheme |
A
7-β-D-xylosylbaccatin III
B
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With Enterobacter sp. CGMCC 2487 pH=8; PBS buffer; Microbiological reaction; |
A
10-deacetylpaclitaxel
B
taxol
C
7-O-(triethylsilyl)paclitaxel
D
7-epipaclitaxel
Conditions | Yield |
---|---|
With trifluoroacetic acid In water; acetic acid at 20℃; for 6h; Solvent; Reagent/catalyst; Concentration; Time; |
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
at 30 - 55℃; for 12h; |
10-deacetylpaclitaxel
Conditions | Yield |
---|---|
With samarium diiodide; 1,2-Diiodoethane; acetic acid In tetrahydrofuran at -5℃; for 1h; | 83% |
Conditions | Yield |
---|---|
Stage #1: 10-deacetylpaclitaxel With Chloroacetamide In tetrahydrofuran at 100℃; for 3h; Stage #2: acetic anhydride In tetrahydrofuran at 100℃; for 3h; Stage #3: With methanol; sodium hydrogencarbonate; thiourea at 20℃; for 1h; Product distribution / selectivity; | 78.8% |
Stage #1: 10-deacetylpaclitaxel With pyridine; Chloroacetamide at 20℃; for 1h; Stage #2: acetic anhydride With pyridine In tetrahydrofuran at 100℃; for 0.5h; Stage #3: With methanol; sodium hydrogencarbonate; thiourea at 20℃; for 1h; Product distribution / selectivity; | 60% |
Stage #1: 10-deacetylpaclitaxel With Chloroacetamide In tetrahydrofuran at 100℃; for 3h; Stage #2: acetic anhydride In tetrahydrofuran at 100℃; for 3h; Stage #3: With sodium hydrogencarbonate; thiourea In methanol at 20℃; for 1h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
Multistep reaction.; | 71% |
Conditions | Yield |
---|---|
Stage #1: 10-deacetylpaclitaxel With 1H-imidazole; chlorinated PS-DES resin In dichloromethane at 20℃; for 24h; Stage #2: butanoic acid anhydride With cerium(III) chloride In tetrahydrofuran at 20℃; for 24h; Stage #3: With pyridine; hydrogen fluoride In tetrahydrofuran at 20℃; for 2h; Further stages.; | 69% |
Conditions | Yield |
---|---|
Multistep reaction.; | 69% |
Conditions | Yield |
---|---|
Multistep reaction.; | 66% |
Conditions | Yield |
---|---|
Multistep reaction.; | 66% |
Conditions | Yield |
---|---|
Multistep reaction.; | 64% |
Conditions | Yield |
---|---|
Multistep reaction.; | 62% |
Conditions | Yield |
---|---|
Multistep reaction.; | 62% |
Conditions | Yield |
---|---|
Multistep reaction.; | 61% |
Conditions | Yield |
---|---|
Stage #1: 10-deacetylpaclitaxel With 1H-imidazole; chlorinated PS-DES resin In dichloromethane at 20℃; for 24h; Stage #2: C17H14O5 With cerium(III) chloride In tetrahydrofuran at 20℃; for 24h; Stage #3: With pyridine; hydrogen fluoride In tetrahydrofuran at 20℃; for 2h; Further stages.; | 60% |
Conditions | Yield |
---|---|
Stage #1: 10-deacetylpaclitaxel With 1H-imidazole; chlorinated PS-DES resin In dichloromethane at 20℃; for 24h; Stage #2: benzoic acid anhydride With cerium(III) chloride In tetrahydrofuran at 20℃; for 24h; Stage #3: With pyridine; hydrogen fluoride In tetrahydrofuran at 20℃; for 2h; Further stages.; | 60% |
Conditions | Yield |
---|---|
Multistep reaction.; | 59% |
Conditions | Yield |
---|---|
Multistep reaction.; | 59% |
Conditions | Yield |
---|---|
Multistep reaction.; | 59% |
Conditions | Yield |
---|---|
Multistep reaction.; | 59% |
Conditions | Yield |
---|---|
Multistep reaction.; | 58% |
10-deacetylpaclitaxel
propionic acid anhydride
cyclopropanecarboxylic acid
Conditions | Yield |
---|---|
Multistep reaction.; | 58% |
10-deacetylpaclitaxel
benzoic acid anhydride
cyclopropanecarboxylic acid
Conditions | Yield |
---|---|
Multistep reaction.; | 58% |
Conditions | Yield |
---|---|
Multistep reaction.; | 57% |
Conditions | Yield |
---|---|
Multistep reaction.; | 56% |
Conditions | Yield |
---|---|
Stage #1: 10-deacetylpaclitaxel With 1H-imidazole; chlorinated PS-DES resin In dichloromethane at 20℃; for 24h; Stage #2: crotonic anhydride With cerium(III) chloride In tetrahydrofuran at 20℃; for 24h; Stage #3: With pyridine; hydrogen fluoride In tetrahydrofuran at 20℃; for 2h; Further stages.; | 56% |
Conditions | Yield |
---|---|
Multistep reaction.; | 56% |
Conditions | Yield |
---|---|
Multistep reaction.; | 55% |
Conditions | Yield |
---|---|
Multistep reaction.; | 54% |
Conditions | Yield |
---|---|
Stage #1: 10-deacetylpaclitaxel With 1H-imidazole; chlorinated PS-DES resin In dichloromethane at 20℃; for 24h; Stage #2: propionic acid anhydride With cerium(III) chloride In tetrahydrofuran at 20℃; for 24h; Stage #3: With pyridine; hydrogen fluoride In tetrahydrofuran at 20℃; for 2h; Further stages.; | 54% |
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