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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

Methyl 2-chloro-2-propenate

Cas:80-63-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Chloro-2-propenoic acid methyl ester

Cas:80-63-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

80-63-7 METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

80-63-7 METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 80-63-7 with competitive price

Cas:80-63-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Propenoic acid,2-chloro-, methyl ester 80-63-7

Cas:80-63-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

METHYL ALPHA-CHLOROACRYLATE CAS:80-63-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

METHYL ALPHA-CHLOROACRYLATE CAS:80-63-7

Cas:80-63-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Propenoic acid,2-chloro-, methyl ester

Cas:80-63-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Propenoic acid,2-chloro-, methyl ester

Cas:80-63-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Propenoic acid,2-chloro-, methyl ester

Cas:80-63-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Methyl 2-chloropropenoate

Cas:80-63-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: METHYL ALPHA-CHLOROACRYLATE Synonyms: METHYL-A-CHLOROACRYLATE;METHYL ALPHA-CHLOROACRYLATE;METHYL CHLOROACRYLATE;METHYL 2-CHLORO-2-PROPENATE;METHYL 2-CHLOROACRYLATE;Methyl alpha-chloroacrylate, stabilized with hydroquinone, 98+%;Me

METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ Methyl 2-chloroacrylate /Manufacturer in China

Cas:80-63-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Methyl 2-chloro-2-propenate

Cas:80-63-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:Used as Pharmaceutical Intermediates Transporta

2-Propenoic acid,2-chloro-, methyl ester

Cas:80-63-7

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

METHYL ALPHA-CHLOROACRYLATE Cas no.80-63-7 98%

Cas:80-63-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

methyl 2-chloroacrylate

Cas:80-63-7

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

2-Propenoic acid,2-chloro-, methyl ester

Cas:80-63-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Methyl 2-chloro-2-propenoate

Cas:80-63-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as:

METHYL ALPHA-CHLOROACRYLATE

Cas:80-63-7

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-Propenoic acid,2-chloro-, methyl ester

Cas:80-63-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

Methyl 2-chloro-2-propenoate

Cas:80-63-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Methyl 2-chloro-2-propenate cas 80-63-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Methyl 2-chloro-2-propenate cas 80-63-7

Cas:80-63-7

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Methyl 2-chloro-2-propenoate

Cas:80-63-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

80-63-7

Cas:80-63-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

Methyl 2-chloro-2-propenoate

Cas:80-63-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

endo-5-Carbomethoxy-6-chloro-1,6-diazabicyclo<3.1.0>hexane
89019-24-9, 108392-47-8, 108392-49-0, 113085-27-1, 113158-29-5

endo-5-Carbomethoxy-6-chloro-1,6-diazabicyclo<3.1.0>hexane

A

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

B

ethene
74-85-1

ethene

Conditions
ConditionsYield
In chloroform-d1 at 80℃; for 10h; Product distribution;A 95%
B n/a
exo-6-chloro-5-methoxycarbonyl-1,6-diazabicyclo<3.1.0>hexane
89019-24-9, 108392-47-8, 108392-49-0, 113085-27-1, 113158-29-5

exo-6-chloro-5-methoxycarbonyl-1,6-diazabicyclo<3.1.0>hexane

A

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

B

ethene
74-85-1

ethene

C

N2

N2

Conditions
ConditionsYield
In dichloromethane at 80℃; for 10h;A 95%
B n/a
C n/a
methyl 2,3-dichloropropionate
3674-09-7, 132854-28-5

methyl 2,3-dichloropropionate

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Conditions
ConditionsYield
In water; dimethyl sulfoxide at 120℃; for 6h;91%
With 10H-phenothiazine; tetrabutylammomium bromide; sodium hydrogencarbonate In dichloromethane; water for 1.5h; Dehydrochlorination; Heating;66%
beim Erhitzen mit protonierten Kationenaustauschern;
2,3,3-trichloropropene-1-ol

2,3,3-trichloropropene-1-ol

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Conditions
ConditionsYield
With sulfuric acid In methanol74%
formaldehyd
50-00-0

formaldehyd

methyl chloroacetate
96-34-4

methyl chloroacetate

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Conditions
ConditionsYield
Stage #1: methyl chloroacetate With Dimethyl oxalate; sodium methylate In dimethyl sulfoxide at 15 - 25℃; for 1h; Inert atmosphere;
Stage #2: formaldehyd With 2,6-di-tert-butyl-4-methyl-phenol In dimethyl sulfoxide at 20 - 25℃; for 1h; Inert atmosphere;
58.1%
methyl-α-bromo-α-chloro-propanoate
166666-36-0

methyl-α-bromo-α-chloro-propanoate

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Conditions
ConditionsYield
With lithium carbonate; lithium bromide In N,N-dimethyl-formamide at 70℃; for 24h;29%
dichloro-methylsulfanyl-acetic acid methyl ester
77825-46-8

dichloro-methylsulfanyl-acetic acid methyl ester

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Conditions
ConditionsYield
In tetrachloromethane at 490℃; Yield given;
exo-6-chloro-5-methoxycarbonyl-1,6-diazabicyclo<3.1.0>hexane
89019-24-9, 108392-47-8, 108392-49-0, 113085-27-1, 113158-29-5

exo-6-chloro-5-methoxycarbonyl-1,6-diazabicyclo<3.1.0>hexane

A

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

B

ethene
74-85-1

ethene

Conditions
ConditionsYield
In chloroform-d1 at 40℃; Rate constant; Mechanism; τ1/2 (h);
methyl 2,2-dichloropropionate
17640-02-7

methyl 2,2-dichloropropionate

benzaldehyde
100-52-7

benzaldehyde

A

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

B

methyl 2-chloro-3-hydroxy-2-methyl-3-phenylpropanoate
80532-67-8

methyl 2-chloro-3-hydroxy-2-methyl-3-phenylpropanoate

Conditions
ConditionsYield
With boron trifluoride; zinc In tetrahydrofuran at 0℃; for 24h;A 3 % Chromat.
B 76 % Chromat.
benzaldehyde
100-52-7

benzaldehyde

methyl-α-bromo-α-chloro-propanoate
166666-36-0

methyl-α-bromo-α-chloro-propanoate

A

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

B

methyl 2-chloro-3-hydroxy-2-methyl-3-phenylpropanoate
80532-67-8

methyl 2-chloro-3-hydroxy-2-methyl-3-phenylpropanoate

C

dimethyl 2,3-dichloro-2,3-dimethylbutanedioate

dimethyl 2,3-dichloro-2,3-dimethylbutanedioate

Conditions
ConditionsYield
With boron trifluoride; zinc In tetrahydrofuran at 0℃; for 3h;A 1 % Chromat.
B 85 % Chromat.
C 8 % Chromat.
methyl-<2.3-dichloro propionate>

methyl-<2.3-dichloro propionate>

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Conditions
ConditionsYield
With water; sodium carbonate; hydroquinone at 150℃; staendiges Abdestillieren des entstandenen Methyl-<2.3-dichlor-acrylats>;
With quinoline
With sodium acetate; isopropyl alcohol
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

2-[[N-(1,3-thiazol-2-yl)methylene]amino]-3-(1H-pyrazol-1-yl)propanoic acid tert-butyl ester
885264-31-3

2-[[N-(1,3-thiazol-2-yl)methylene]amino]-3-(1H-pyrazol-1-yl)propanoic acid tert-butyl ester

C18H23ClN4O4S

C18H23ClN4O4S

Conditions
ConditionsYield
With triethylamine; lithium bromide In tetrahydrofuran at 20℃; for 17h;100%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

Methyl thioglycolate
2365-48-2

Methyl thioglycolate

α-Chlor-β-<(methoxycarbonylmethyl)thio>propansaeure-methylester
90237-73-3

α-Chlor-β-<(methoxycarbonylmethyl)thio>propansaeure-methylester

Conditions
ConditionsYield
With sodium In dichloromethane at 25℃; for 0.666667h;99%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

benzenecarbothioamide
2227-79-4

benzenecarbothioamide

S-<2-Chlor-2-(methoxycarbonyl)ethyl>thiobenzamid-hydrochlorid
116077-23-7

S-<2-Chlor-2-(methoxycarbonyl)ethyl>thiobenzamid-hydrochlorid

Conditions
ConditionsYield
With hydrogenchloride In dichloromethane for 72h; Ambient temperature;98%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol
335-99-9

2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol

dodecafluoroheptyl 2-chloroacrylate

dodecafluoroheptyl 2-chloroacrylate

Conditions
ConditionsYield
With 10H-phenothiazine; tetrakis(1H,1H,7H-perfluoroheptyl) titanate; hydroquinone In toluene at 80℃; for 3.5h; Large scale;97.1%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

phenylmethanethiol
100-53-8

phenylmethanethiol

2-Chlor-3-(benzylthio)propansaeure-methylester
60741-22-2

2-Chlor-3-(benzylthio)propansaeure-methylester

Conditions
ConditionsYield
With sodium benzylmercaptide In dichloromethane for 4h; Ambient temperature;95%
With sodium methylate
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

methylenecyclohexane
1192-37-6

methylenecyclohexane

Methyl α-chloro-1-cyclohexene-1-butanoate
89398-16-3

Methyl α-chloro-1-cyclohexene-1-butanoate

Conditions
ConditionsYield
With ethylaluminum dichloride In hexane; benzene at 25℃; for 20h;95%
With ethylaluminum dichloride In hexane; benzene at 25℃; for 24h;95%
With 1-menthyloxyaluminium dichloride In benzene Product distribution; Et2AlCl catalyzed ene reactions of α-substituted acrylate esters with trans 1,2-di and trisubstituted alkenes; regio- and stereoselectivity; reactivity of alkenes and acrylate esters; asymmetric induction;22%
With 1-menthyloxyaluminium dichloride22%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

cesium 2-((1-methylcyclohexyl)oxy)-2-oxoacetate

cesium 2-((1-methylcyclohexyl)oxy)-2-oxoacetate

methyl 2-chloro-3-(1-methylcyclohexyl)propanoate

methyl 2-chloro-3-(1-methylcyclohexyl)propanoate

Conditions
ConditionsYield
With Ir[dF(CF3)ppy]2(dtbbpy)PF6 In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide at 40℃; for 24h; Irradiation; Inert atmosphere;94%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

methyl 2-nitroacetate
2483-57-0

methyl 2-nitroacetate

C7H10ClNO6

C7H10ClNO6

Conditions
ConditionsYield
With DBN In N,N-dimethyl-formamide at 60 - 65℃; for 4h; Solvent; Temperature;92.7%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

thiophenol
108-98-5

thiophenol

α-Chlor-β-(phenylthio)propansaeure-methylester
42801-75-2

α-Chlor-β-(phenylthio)propansaeure-methylester

Conditions
ConditionsYield
With sodium thiophenolate In dichloromethane at 25℃; for 5h;91%
With sodium thiophenolate In dichloromethane for 4h; Ambient temperature;91%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

dimethyl phenylphosphonate
2240-41-7

dimethyl phenylphosphonate

phenol
108-95-2

phenol

Methyl 3-(phenyl-methoxyphosphinyl)-2-chloropropionate

Methyl 3-(phenyl-methoxyphosphinyl)-2-chloropropionate

Conditions
ConditionsYield
90.1%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

thioacetamide
62-55-5

thioacetamide

S-<2-Chlor-2-(methoxycarbonyl)ethyl>thioacetamid-hydrochlorid
116077-24-8

S-<2-Chlor-2-(methoxycarbonyl)ethyl>thioacetamid-hydrochlorid

Conditions
ConditionsYield
With hydrogenchloride In dichloromethane for 18h; Ambient temperature;88%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

methylhydrazine
60-34-4

methylhydrazine

1-methyl-1,2-dihydro-3H-pyrazol-3-one
52867-35-3

1-methyl-1,2-dihydro-3H-pyrazol-3-one

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 25℃; for 10h;88%
In tetrahydrofuran at 20℃; for 16.08h;84%
In tetrahydrofuran at 20 - 50℃; for 17h;77%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

nitromethane
75-52-5

nitromethane

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

5-nitro-2-hydroxypyridine
5418-51-9

5-nitro-2-hydroxypyridine

Conditions
ConditionsYield
Stage #1: methyl 2-chloroacrylate; nitromethane With 1,8-diazabicyclo[5.4.0]undec-7-ene at 50 - 55℃; for 5h;
Stage #2: orthoformic acid triethyl ester With zinc(II) chloride at 95 - 100℃; for 4h;
Stage #3: With ammonium hydroxide; ammonium chloride In methanol at 50 - 55℃; for 6h;
87.8%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

methylthiol
74-93-1

methylthiol

2-Chlor-3-(methylthio)propansaeure-methylester
20444-25-1

2-Chlor-3-(methylthio)propansaeure-methylester

Conditions
ConditionsYield
With sodium thiomethoxide In dichloromethane for 4h; Ambient temperature;87%
With sodium methylate; benzene
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

ethyl 3-amino-4,4,4-trifluoro-2-butenoate
372-29-2, 141860-78-8

ethyl 3-amino-4,4,4-trifluoro-2-butenoate

6-hydroxy-2-(trifluoromethyl)nicotinic acid

6-hydroxy-2-(trifluoromethyl)nicotinic acid

Conditions
ConditionsYield
Stage #1: methyl 2-chloroacrylate; ethyl 3-amino-4,4,4-trifluoro-2-butenoate With sodium ethanolate In ethanol at 22 - 23℃; for 2.5h; Inert atmosphere;
Stage #2: With water; sodium hydroxide In ethanol at 70 - 75℃;
87%
methanol
67-56-1

methanol

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

α-Chlor-β-methoxypropansaeure-methylester
36997-03-2

α-Chlor-β-methoxypropansaeure-methylester

Conditions
ConditionsYield
With sodium 0 degC, 1 h then r.t., 2 h;86%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

3-Methyl-cis-2-penten
922-62-3

3-Methyl-cis-2-penten

(2S,4R)-2-Chloro-4-methyl-5-methylene-heptanoic acid methyl ester
74964-45-7

(2S,4R)-2-Chloro-4-methyl-5-methylene-heptanoic acid methyl ester

Conditions
ConditionsYield
With ethylaluminum dichloride In benzene at 25℃; for 19.2h;86%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

mercaptoacetic acid
68-11-1

mercaptoacetic acid

3-(Carboxymethylthio)-2-chlorpropansaeure-methylester
116077-17-9

3-(Carboxymethylthio)-2-chlorpropansaeure-methylester

Conditions
ConditionsYield
With sodium hydroxide In water at 10℃; for 24h;86%
2-(2-aminophenyl)-3-cyclohexyl-1H-indole-6-carboxylic acid methyl ester
863578-19-2

2-(2-aminophenyl)-3-cyclohexyl-1H-indole-6-carboxylic acid methyl ester

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

dimethyl 13-cyclohexyl-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepine-6,10-dicarboxylate
956580-06-6

dimethyl 13-cyclohexyl-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepine-6,10-dicarboxylate

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium carbonate In acetonitrile at 60℃;84%
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile at 60℃;75%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

(E)-3-methyl-2-pentene
616-12-6

(E)-3-methyl-2-pentene

(Z)-(2S,4R)-2-Chloro-4,5-dimethyl-hept-5-enoic acid methyl ester
74964-46-8, 80865-34-5, 80865-37-8

(Z)-(2S,4R)-2-Chloro-4,5-dimethyl-hept-5-enoic acid methyl ester

(E)-(2S,4R)-2-Chloro-4,5-dimethyl-hept-5-enoic acid methyl ester
74964-46-8

(E)-(2S,4R)-2-Chloro-4,5-dimethyl-hept-5-enoic acid methyl ester

Conditions
ConditionsYield
With ethylaluminum dichloride In benzene at 25℃; for 14.4h; Yields of byproduct given;A n/a
B 82%
With ethylaluminum dichloride In benzene at 25℃; for 14.4h; Product distribution; Mechanism; regiospecificity; further alkenes;
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

methyl chloroacetate
96-34-4

methyl chloroacetate

cis-1,2-Di(methoxycarbonyl)-1-chlorcyclopropan
39822-01-0, 39822-02-1

cis-1,2-Di(methoxycarbonyl)-1-chlorcyclopropan

Conditions
ConditionsYield
With potassium hydride In N,N-dimethyl-formamide at 25℃; for 6h;80%
n-butyl magnesium bromide
693-03-8

n-butyl magnesium bromide

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

1-chloro-2-pentyl-cyclopropane-1,2-dicarboxylic acid dimethyl ester

1-chloro-2-pentyl-cyclopropane-1,2-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With copper(l) chloride In diethyl ether at -78℃; Michael addition;80%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

1-chloro-2-propyl-cyclopropane-1,2-dicarboxylic acid dimethyl ester

1-chloro-2-propyl-cyclopropane-1,2-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With copper(l) chloride In diethyl ether at -78℃; Michael addition;78%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

isopropylmagnesium chloride
1068-55-9

isopropylmagnesium chloride

1-chloro-2-isobutyl-cyclopropane-1,2-dicarboxylic acid dimethyl ester

1-chloro-2-isobutyl-cyclopropane-1,2-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With copper(l) chloride In diethyl ether at -78℃; Michael addition;76%
methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

1,3-dithiapropane
6725-64-0

1,3-dithiapropane

3,3'-bis(2-chlorpropansaeure-methylester)
116077-16-8

3,3'-bis(2-chlorpropansaeure-methylester)

Conditions
ConditionsYield
With triethylamine In diethyl ether at 0℃; for 0.166667h;75%
2-methyl-but-2-ene
513-35-9

2-methyl-but-2-ene

methyl 2-chloroacrylate
80-63-7

methyl 2-chloroacrylate

(2R,4S)-2-Chloro-4,5-dimethyl-hex-5-enoic acid methyl ester
74964-44-6

(2R,4S)-2-Chloro-4,5-dimethyl-hex-5-enoic acid methyl ester

Conditions
ConditionsYield
With ethylaluminum dichloride In benzene at 25℃; for 28.8h;74%
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