Quality Standard: USP 41, EP 9.4 Certification: US-FDA, CEP, GMP Guaifenesin is used to try to help with coughing up thick mucous and is sometimes combined with dextromethorphan, an antitussive (cough medicine), such as in Mucinex DM or Robitus
As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:93-14-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryJinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu
Cas:93-14-1
Min.Order:1 Gram
Negotiable
Type:Manufacturers
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White crystalline powder Storage:Refrigerator Package:25kg/dr
Cas:93-14-1
Min.Order:25 Kilogram
FOB Price: $10.0 / 65.0
Type:Trading Company
inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:93-14-1
Min.Order:1 Gram
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inquiryADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,
Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:93-14-1
Min.Order:1 Kilogram
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Type:Manufacturers
inquiryName:guaifenesin CAS NO:93-14-1 Grade:Medical scientific research and export Molecular formula:C10H14O4 Molecular weight:198.21 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data s
Cas:93-14-1
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryOur advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥99% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c
Cas:93-14-1
Min.Order:20 Metric Ton
FOB Price: $299.0 / 399.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:93-14-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Name: Guaifenesin Synonyms: 3-(2-Methoxyphenoxy)-1,2-propanediol CAS: 93-14-1 MF: C10H14O4 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package: 25KG/Barrel Application:APIs Transportation:By sea or by air Por
Appearance:White Solid Storage:R.T Package:25kg/drum Application:3-(2-Methoxyphenoxy)-1,2-propanediol is an expectorant and antitussive drug, suitable for expectorant cough, chronic bronchitis, bronchiectasis and other diseases. Transportation:Expre
Cas:93-14-1
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryAmoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:93-14-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Guaifenesin CAS:93-14-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s
Cas:93-14-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Guaifenesin CAS: 93-14-1 Specification Appearance & Physical State White Solid Density 1.195 g/cm3 Boiling Point 215ºC (19 mmHg) Melting Point 77-81ºC Flash Point 169.6º
1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Cas:93-14-1
Min.Order:1 Kilogram
FOB Price: $40.0 / 50.0
Type:Lab/Research institutions
inquiryPRODUCT DETAILS
Cas:93-14-1
Min.Order:500 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryminimum order qty. 10 gram
Cas:93-14-1
Min.Order:10 Gram
Negotiable
Type:Trading Company
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic
Product Name: Guaifenesin Synonyms: 1,2-Dihydroxy-3-(2-methoxyphenoxy)propane;1,2-Propanediol, 3-(2-methoxyphenoxy)-;1,2-Propanediol, 3-(o-methoxyphenoxy)-;2/G;2-G;3-(2-Methoxyphenosy)-1,2-propamediol;3-(2-methoxyphenoxy)-2-propanediol;3-(o-meth
Cas:93-14-1
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Guaifenesin CAS 93-14-1 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,
Cas:93-14-1
Min.Order:1 Kilogram
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Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
oxiranyl-methanol
2-methoxy-phenol
A
2-(2-methoxyphenoxy)-1,3-propanediol
B
guaifenesin
Conditions | Yield |
---|---|
With calcined hydrotalcite In tetrahydrofuran at 120℃; for 4h; Kinetics; Reagent/catalyst; Temperature; Autoclave; | A 5% B 95% |
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 65 - 70℃; for 12h; | 90% |
With sodium hydroxide at 90 - 95℃; | 56% |
With tetrabutylammomium bromide; potassium carbonate; palladium dichloride In water at 60℃; for 5h; | 55% |
Stage #1: 2-methoxy-phenol With potassium hydroxide at 64.84℃; Inert atmosphere; Stage #2: oxiranyl-methanol With hydrogenchloride Inert atmosphere; |
Conditions | Yield |
---|---|
With perchloric acid | 81% |
With perchloric acid In water at 80℃; | 80% |
With sulfuric acid; water at 70℃; for 2h; | 59.1% |
Conditions | Yield |
---|---|
With sodium hydroxide In N,N-dimethyl-formamide at 210℃; for 0.25h; Microwave irradiation; | 75% |
Stage #1: 2-methoxy-phenol With sodium hydroxide In ethanol; water for 0.5h; Heating; Stage #2: 3-monochloro-1,2-propanediol In ethanol; water for 8h; Heating; | 61% |
With sodium hydroxide |
Conditions | Yield |
---|---|
Stage #1: 2-methoxy-phenol With potassium chloride; sodium sulfite at 50℃; for 3h; Reflux; Stage #2: 3-Amino-1,2-propanediol at 90℃; for 5h; Temperature; Concentration; | 72% |
4-hydroxymethyl-1,3-dioxolan-2-one
2-methoxy-phenol
A
1,3-bis(2-methoxyphenoxy)propan-2-ol
B
guaifenesin
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In N,N-dimethyl-formamide at 160℃; for 9.5h; Inert atmosphere; Schlenk technique; | A 9% B 64% |
Conditions | Yield |
---|---|
With ethanol |
methocarbamol
A
3-(2-methoxyphenoxy)propanediol 2-carbamate
B
guaifenesin
Conditions | Yield |
---|---|
With water at 70℃; Product distribution; Rate constant; further temperatures, pH 8.0-10.0; |
Conditions | Yield |
---|---|
With potassium carbonate In acetone |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 43 percent / NaOH / 16 h / 80 °C 2: 81 percent / perchloric acid View Scheme | |
Multi-step reaction with 2 steps 1: 2.) 50percent aq. NaOH / 1.) 80 deg C, 2.) 4 h 2: 80 percent / 72percent HClO4 / H2O / 80 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NaOEt / ethanol 2: K2CO3 / acetone View Scheme |
2-methoxy-phenol
epichlorohydrin
A
1-chloro-3-(2-methoxyphenoxy)-2-propyl alcohol
B
1,3-bis(2-methoxyphenoxy)propan-2-ol
C
guaifenesin
D
2-(2-methoxy-phenoxymethyl)-oxirane
Conditions | Yield |
---|---|
With sodium hydroxide In toluene at 25 - 30℃; Solvent; Concentration; |
Conditions | Yield |
---|---|
With potassium carbonate; Diethyl carbonate at 105 - 110℃; for 8h; | 78 %Spectr. |
Conditions | Yield |
---|---|
With ethanol In water at 80℃; |
guaifenesin
Conditions | Yield |
---|---|
With hydrogenchloride In water at 37℃; pH=0.2; Kinetics; pH-value; |
guaifenesin
Conditions | Yield |
---|---|
With hydrogenchloride In water at 37℃; pH=0.2; Kinetics; pH-value; |
guaifenesin
Conditions | Yield |
---|---|
With hydrogenchloride In water at 37℃; pH=0.2; Kinetics; pH-value; |
guaifenesin
Conditions | Yield |
---|---|
With hydrogenchloride In water at 37℃; pH=0.2; Kinetics; pH-value; |
guaifenesin
Conditions | Yield |
---|---|
With hydrogenchloride In water at 37℃; pH=0.2; Kinetics; pH-value; |
guaifenesin
Conditions | Yield |
---|---|
With hydrogenchloride In water at 37℃; pH=0.2; Kinetics; pH-value; |
Conditions | Yield |
---|---|
In water at 35 - 50℃; for 1h; Product distribution / selectivity; | 96.15% |
guaifenesin
2(2-methoxyphenoxy)ethanale
Conditions | Yield |
---|---|
With sodium periodate In water at 10℃; for 1h; | 95% |
guaifenesin
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 94% |
guaifenesin
tert-butyldimethylsilyl chloride
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere; | 94% |
guaifenesin
acetic anhydride
(RS)-3-(2-methoxyphenoxy)-propane-1,2-diyl diacetate
Conditions | Yield |
---|---|
With pyridine at 4℃; for 4h; | 90% |
Conditions | Yield |
---|---|
Stage #1: guaifenesin With sodium hydride In tetrahydrofuran; mineral oil for 0.5h; Stage #2: 2,2-dimethylsuccinic anhydride In tetrahydrofuran; mineral oil at 20℃; | 90% |
Conditions | Yield |
---|---|
With phosphorus pentoxide; silica gel In acetonitrile at 20℃; | 88% |
carbon monoxide
guaifenesin
rac-4-(2-methoxyphenoxymethyl)-[1,3]dioxolan-2-one
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; oxygen; sodium acetate; potassium iodide In 1,2-dimethoxyethane at 100℃; under 10343.2 Torr; for 3h; Autoclave; Inert atmosphere; | 86% |
Conditions | Yield |
---|---|
With phosphorus pentoxide; silica gel In acetonitrile at 20℃; | 85% |
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 83% |
N-methylsulfamoyl chloride
guaifenesin
1-[(2-Methoxyphenoxy)methyl]-1,2-ethanediol bis(methylsulfamate) (ester)
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane for 2h; Ambient temperature; | 82% |
guaifenesin
1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose
3-(2-methoxyphenoxy)-1-O-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)propane-1,2-diol
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 4h; | 82% |
guaifenesin
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 82% |
guaifenesin
1-O-acetyl-2,3,5-tri-O-benzoyl-D-xylofuranose
3-(2-methoxyphenoxy)-1-O-(2,3,5-tri-O-benzoyl-β-D-xylofuranosyl)propane-1,2-diol
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 5h; | 80% |
guaifenesin
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 80% |
guaifenesin
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 80% |
Conditions | Yield |
---|---|
In ethanol; N,N-dimethyl-formamide at 70℃; for 1.5h; Reflux; | 80% |
Conditions | Yield |
---|---|
Stage #1: guaifenesin With sodium hydride In tetrahydrofuran; mineral oil for 0.5h; Stage #2: maleic anhydride In tetrahydrofuran; mineral oil at 20℃; | 80% |
guaifenesin
acetic anhydride
A
(RS)-3-(2-methoxyphenoxy)-propane-1,2-diyl diacetate
B
1-O-acetyl-3-(2-methoxyphenoxy)propane-1,2-diol
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 20℃; for 3h; | A 10% B 78% |
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 75% |
1-benzoylimidazole
guaifenesin
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 50℃; for 8h; regioselective reaction; | A 75% B 15% |
Conditions | Yield |
---|---|
With ammonium hydroxide In methanol at 70℃; pH=8 - 9; | 74% |
guaifenesin
CVT-4786
Conditions | Yield |
---|---|
Stage #1: guaifenesin With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In aq. phosphate buffer; toluene at 25℃; for 0.0833333h; pH=6.8; Stage #2: With sodium hypochlorite; sodium chlorite In aq. phosphate buffer; water; toluene at 50℃; for 24h; pH=6.8; | 73% |
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite In water; acetonitrile at 35℃; aq. phosphate buffer; chemoselective reaction; | 37.4% |
Conditions | Yield |
---|---|
Stage #1: guaifenesin With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In aq. phosphate buffer; toluene at 25℃; pH=6.8; Stage #2: With sodium hypochlorite; sodium chlorite In aq. phosphate buffer; toluene at 50℃; for 24h; chemoselective reaction; | A 10 %Spectr. B 73% |
Conditions | Yield |
---|---|
With ammonium hydroxide In methanol at 70℃; pH=8 - 9; | 73% |
Conditions | Yield |
---|---|
Stage #1: guaifenesin With sodium hydride In tetrahydrofuran; mineral oil for 0.5h; Stage #2: 2,3-Dimethylmaleic anhydride In tetrahydrofuran; mineral oil at 20℃; | 73% |
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