55314-30-2Relevant articles and documents
DERIVATIVES OF 4-(N-AZACYCLOALKYL) ANILIDES AS POTASSIUM CHANNEL MODULATORS
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Page/Page column 19-20, (2009/01/24)
This invention provides potassium channel modulators which are compounds of formula I where at least one of W and Z is N; where the moiety is one of Groups A or B below A where Ar is a 1,2-fused, six membered ring aromatic group, bearing substituents R1 and R2 as defined below, and containing zero or one ring nitrogen atom; and where other substituents are defined herein. The invention also provides a composition comprising a pharmaceutically acceptable carrier and at least one of the following: i) a pharmaceutically effective amount of a compound of formula I and ii) a pharmaceutically acceptable salt, ester, or prodrug thereof. The invention also provides a method of preventing or treating a disease or disorder which is affected by activities of potassium channels, comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula I or a salt, ester, or prodrug thereof.
A Model Study of the Role of the CONH2-group in the Redox Co-enzyme NAD(P)+-NAD(P)H. Chirality in 2,4-dimethyl-3-carbamoylpyridinium Cations
Hooff,H. J. G. van,Lier, P. M. van,Bastiaansen, L. A. M.,Buck, H. M.
, p. 191 - 192 (2007/10/02)
Experimental verification of chirality in 2,4-dimethyl-3-carbamoylpyridinium cations.