1,2,4-Trifluorobenzene supplier

Name
1,2,4-Trifluorobenzene
EINECS 206-684-9
CAS No. 367-23-7
Article Data58
CAS DataBase
Density 1.294 g/cm³
Solubility
Melting Point -35oC
Formula C₆H₃F₃
Boiling Point 90.7 °C at 760 mmHg
Molecular Weight 132.085
Flash Point 4.4 °C
Transport Information UN 1993 3/PG 2
Appearance clear colourless liquid
Safety 16-26-36-7-33-29-7/9
Risk Codes 11-36/37/38
Molecular Structure
Hazard Symbols F,Xi
Synonyms 1,3, 4-Trifluorobenzene;Benzene, 1,2,4-trifluoro-;1,3,4-Trifluorobenzene, misnomer;
PSA 0.00000
LogP 2.10390

Synthetic route

: 7800-26-2
2,4-dinitro-1-fluorobenzene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In dimethyl sulfoxide at 25℃; for 0.166667h; Inert atmosphere; Microwave irradiation; Anhydrous conditions;	95%

: 446-17-3
2,4,5-trifluorobenzoic acid

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With ammonia; copper In water at 260℃; for 1.25h; Temperature; Reagent/catalyst;	94.9%
In quinoline

: 551-62-2
1,2,3,4-tetrafluorobenzene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With [(bis(diisopropylphosphino)ethane)Ni(H)]2; triethylphosphine In 1,4-dioxane at 120℃; for 72h;	94%
With C32H46N2Ru; sodium carbonate; isopropyl alcohol at 70℃; for 6h; Inert atmosphere; Schlenk technique; Glovebox;	63%
With (1,3-dimethylimidazolin-2-ylidene)*AlH3 In 5,5-dimethyl-1,3-cyclohexadiene at 135℃; for 25h;	19%

: 165047-24-5
2,4,5-trifluorobenzaldehyde

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With triethylsilane; C18H51CoP4Si In tetrahydrofuran at 50℃; for 6h; Inert atmosphere;	94%

: 769-40-4
2,3,5,6-tetrafluorothiophenol

A: 651-80-9
1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene

B: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With water; triethylphosphine In 1,4-dioxane at 120℃; for 4h; Schlenk technique; Inert atmosphere; Glovebox;	A 90% B 10%

: C6H3FN4(2+)*2BF4(1-)

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
In diethyl ether at 120 - 180℃; for 6h;	82%

: 367-25-9
2,4-difluorophenylamine

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
Stage #1: 2,4-difluorophenylamine With sodium tetrafluoroborate; nitrosylsulfuric acid; acetic acid at -5 - 20℃; Stage #2: at 250℃; Inert atmosphere;	80%
Stage #1: 2,4-difluorophenylamine With hydrogenchloride; fluoroboric acid; sodium nitrite In water at 25℃; for 0.00555556h; Balz-Schiemann Reaction; Stage #2: In 1,2-dichloro-benzene at 200℃; for 0.0166667h; Balz-Schiemann Reaction;	72%

: 120-82-1
1,2,4-Trichlorobenzene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With potassium fluoride; C6H11BO3 In sulfolane (tetramethylene sulfone) at 245℃; for 3h; Inert atmosphere;	78%

: 392-56-3
Hexafluorobenzene

A: 327-54-8
1,2,4,5-Tetrafluorobenzene

B: 551-62-2
1,2,3,4-tetrafluorobenzene

C: 363-72-4
Pentafluorobenzene

D: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With (1,3-dimethylimidazolin-2-ylidene)*AlH3 In 5,5-dimethyl-1,3-cyclohexadiene at 135℃; for 25h;	A 74% B 3% C 18% D 4%

...Expand

: 363-72-4
Pentafluorobenzene

A: 540-36-3
para-difluorobenzene

B: 327-54-8
1,2,4,5-Tetrafluorobenzene

C: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With C32H46N2Ru; sodium carbonate; isopropyl alcohol at 70℃; for 4h; Inert atmosphere; Schlenk technique; Glovebox;	A 7% B 60% C 21%

...Expand

: 2,4-difluorophenyldiazonium tetrafluoroborate

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
at 185℃; for 1h; Decomposition;	52%
Pyrolysis;

: 327-54-8
1,2,4,5-Tetrafluorobenzene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With C32H46N2Ru; sodium carbonate; isopropyl alcohol at 70℃; for 6h; Inert atmosphere; Schlenk technique; Glovebox;	48%
With H2SiEt2; tetrabutylammonium triphenyldifluorosilicate In tetrahydrofuran; benzene-d6 at 100℃; for 40h; Inert atmosphere; Sealed tube;	18%

: 327-54-8
1,2,4,5-Tetrafluorobenzene

A: 540-36-3
para-difluorobenzene

B: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
Stage #1: 1,2,4,5-Tetrafluorobenzene With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; [(HC[(CMe)N(2,4,6-Me3C6H2)]2)Al(H)2] In benzene-d6; benzene at 100℃; for 8h; Inert atmosphere; Glovebox; Sealed tube; Stage #2: With methanol In benzene-d6; benzene at 100℃; for 2h; Catalytic behavior; Inert atmosphere; Glovebox; Sealed tube; regioselective reaction;	A 19.5% B 47%

: 2367-82-0
1,2,3,5-tetrafluorobenzene

A: 1489-53-8
1,2,3-trifluorobenzene

B: 372-18-9
1,3-Difluorobenzene

C: 540-36-3
para-difluorobenzene

D: 367-11-3
ortho-difluorobenzene

E: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
Stage #1: 1,2,3,5-tetrafluorobenzene With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; [(HC[(CMe)N(2,4,6-Me3C6H2)]2)Al(H)2] In benzene-d6; benzene at 100℃; for 8h; Inert atmosphere; Glovebox; Sealed tube; Stage #2: With methanol In benzene-d6; benzene at 100℃; for 2h; Catalytic behavior; Inert atmosphere; Glovebox; Sealed tube; Overall yield = 69.5 %; regioselective reaction;	A 8.5% B 9.5% C 7% D 5.5% E 39%

...Expand

: 367-11-3
ortho-difluorobenzene

A: 367-23-7
1,2,4-trifluorobenzene

B: 74298-22-9
5,5,6,6-tetrafluoro-1,3-cyclohexadiene

C: 74298-21-8
2,3,3,6-tetrafluoro-1,4-cyclohexadiene

Conditions

Conditions	Yield
With silver(II) fluoride In hexane for 2h; Product distribution; Heating;	A 3% B 15.7% C 28%
With silver(II) fluoride In hexane for 2h; Heating;	A 3% B 15.7% C 28%

...Expand

: 2713-09-9
fluoroethyne

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
Raumtemperatur;
at 20℃;

: 540-36-3
para-difluorobenzene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
durch Nitrierung, Reduktion, Diazotierung und Zersetzung des entsprechenden Diazoniumbortetrafluorids durch Erhitzen;

: 2,5-difluorobenzenediazonium tetrafluoroborate

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
Pyrolysis;

: 106-51-4
p-benzoquinone

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With sulfur tetrafluoride; hydrogen fluoride at 200℃;

: 2,3,5-Trifluorbicyclo<2.2.0>hexa-3,5-dien

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With (thermolysis) at 79.9℃; Rate constant;

: 1,2,5-Trifluorbicyclo<2.2.0>hexa-2,5-dien

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With (thermolysis) at 79.9℃; Rate constant;

: 31399-10-7
1,2,5-trifluorobicyclo<2.2.0>hexa-2,5-diene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
at 79.9℃; Rate constant; gas-phase thermal isomerization;

: 2367-78-4
5-chloro-1,2,4-trifluorobenzene

: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol Heating;
palladium-carbon

: 685-63-2
hexafluoro-1,3-butadiene

: 106-99-0
buta-1,3-diene

A: 1489-53-8
1,2,3-trifluorobenzene

B: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With pyrographite; hydroquinone 1. heating, 2. pyrolysis; Multistep reaction;

...Expand

: 685-63-2
hexafluoro-1,3-butadiene

: 106-99-0
buta-1,3-diene

A: 1489-53-8
1,2,3-trifluorobenzene

B: 367-23-7
1,2,4-trifluorobenzene

C: 92818-42-3
1,2,2,5,6,6-hexafluorotricyclo<3.3.0.06,8>octane

Conditions

Conditions	Yield
With pyrographite; hydroquinone 1. heating, 2. pyrolysis; Multistep reaction;

...Expand

: 71-43-2
benzene

A: 462-06-6
fluorobenzene

B: 540-36-3
para-difluorobenzene

C: 367-11-3
ortho-difluorobenzene

D: 327-54-8
1,2,4,5-Tetrafluorobenzene

E: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With tetrafluoroammonium tetrafluoroborate In hydrogen fluoride at 0℃; Product distribution; NF4BF4 to benzene ratio;	A 33 % Spectr. B 27 % Spectr. C 7 % Spectr. D 15 % Spectr. E 18 % Spectr.

...Expand

: 71-43-2
benzene

A: 462-06-6
fluorobenzene

B: 540-36-3
para-difluorobenzene

C: 367-11-3
ortho-difluorobenzene

D: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With tetrafluoroammonium tetrafluoroborate In hydrogen fluoride at 0℃; Further byproducts given. Title compound not separated from byproducts;	A 33 % Spectr. B 27 % Spectr. C 7 % Spectr. D 18 % Spectr.

...Expand

: C6H4F3(1+)

: 71-43-2
benzene

A: 367-23-7
1,2,4-trifluorobenzene

B: 21246-79-7, 79431-04-2, 87044-94-8, 91808-22-9
cyclohexa-1->5-dienylium

Conditions

Conditions	Yield
at 26.9℃; Rate constant; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.);

...Expand

: 372-18-9
1,3-Difluorobenzene

A: 327-54-8
1,2,4,5-Tetrafluorobenzene

B: 367-23-7
1,2,4-trifluorobenzene

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; fluorine In trichlorofluoromethane at -15℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

: 540-36-3
para-difluorobenzene

A: 367-23-7
1,2,4-trifluorobenzene

B: 2713-31-7
2,5-difluorophenol

C: 703-16-2
4H/5H-3,3,4,5,6,6-Hexafluor-cyclohexen

D: 22060-77-1
3,3,6,6-tetrafluoro-1,4-cyclohexadiene

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; fluorine In trichlorofluoromethane at -25℃; for 3h; Further byproducts given. Title compound not separated from byproducts;

...Expand

: 367-23-7
1,2,4-trifluorobenzene

: 42096-74-2
1,2,4-trifluoro-3-nitrobenzene

Conditions

Conditions	Yield
With sulfuric acid; nitric acid at 50℃; for 4h; Temperature;	99.2%

: 773837-37-9
sodium cyanide

: 75-09-2
dichloromethane

: 367-23-7
1,2,4-trifluorobenzene

: 209995-38-0
(2,4,5-trifluorophenyl)acetic acid

Conditions

Conditions	Yield
Stage #1: sodium cyanide With sodium stearate; nitrobenzene; sodium hydroxide In water at 115℃; under 3420.23 Torr; for 0.75h; Inert atmosphere; Stage #2: dichloromethane; 1,2,4-trifluorobenzene at 6 - 142℃; under 2280.15 - 5320.36 Torr; for 6h; Solvent; Pressure; Reagent/catalyst; Further stages;	99.2%

...Expand

: 69550-28-3
(tri-tert-butylphosphane)gold(I) chloride

: 367-23-7
1,2,4-trifluorobenzene

: 1224321-78-1
((CH3)3C)3PAuC6H2F3

Conditions

Conditions	Yield
With Ag2O; K2CO3; pivalic acid In dimethylformamide react. gold complex with arene in DMF at 50°C for 2 h in the presence of Ag2O, K2CO3 and pivalic acid;	99%

: 367-23-7
1,2,4-trifluorobenzene

: 327-52-6
1-bromo-2,4,5-trifluorobenzene

Conditions

Conditions	Yield
With bromine; acetic acid at 20℃; for 2h; Reagent/catalyst; Temperature;	98.7%
With bromine; iron Reagent/catalyst; Inert atmosphere;	92%
With bromine; iron

: potassium cyanide

: 75-09-2
dichloromethane

: 367-23-7
1,2,4-trifluorobenzene

: 209995-38-0
(2,4,5-trifluorophenyl)acetic acid

Conditions

Conditions	Yield
Stage #1: potassium cyanide With sodium stearate; nitrobenzene; potassium hydroxide In water at 100℃; under 2280.15 Torr; for 0.5h; Inert atmosphere; Stage #2: dichloromethane; 1,2,4-trifluorobenzene at 6 - 130℃; under 2280.15 - 3800.26 Torr; Further stages;	98.2%

...Expand

: 367-23-7
1,2,4-trifluorobenzene

: 431-03-8
dimethylglyoxal

: 3-hydroxy-3-(2,3,6-trifluorophenyl)butan-2-one

Conditions

Conditions	Yield
Stage #1: 1,2,4-trifluorobenzene With n-butyllithium; diisopropylamine In tetrahydrofuran at -70 - -40℃; for 0.5h; Stage #2: dimethylglyoxal In tetrahydrofuran at -70 - -45℃; for 1h; Stage #3: With water; acetic acid In tetrahydrofuran	98%

: 367-23-7
1,2,4-trifluorobenzene

: 79-04-9
chloroacetyl chloride

: 129604-31-5
2,4,5-trifluoro-α-chloroacetophenone

Conditions

Conditions	Yield
With aluminium trichloride Acylation;	95%
With aluminum (III) chloride at 70℃; for 16h;	93%
aluminium chloride In ice-water; dichloromethane

: 5308-25-8
4-ethylpiperazine

: 367-23-7
1,2,4-trifluorobenzene

: 6952-68-7
1,2,4-triazolo<4,3-a>pyridin-3-thiol

: 3-((2-(4-(2,4-difluorophenyl)-piperazin-1-yl)ethyl)thio)-[1,2,4]triazolo[4,3-a]pyridine

Conditions

Conditions	Yield
With sodium sulfide; lithium hydroxide In N,N-dimethyl-formamide at 80℃; for 12h;	95%

...Expand

: 1117-71-1, 56699-18-4, 6000-00-6
methyl-4-bromo-2-butenoate

: 367-23-7
1,2,4-trifluorobenzene

: 1260029-44-4
(E)-4-(2,4,5-trifluoro-phenyl)-but-2-enoic acid methyl ester

Conditions

Conditions	Yield
Stage #1: 1,2,4-trifluorobenzene With isopropylmagnesium chloride In tetrahydrofuran at -20 - -10℃; for 1h; Inert atmosphere; Stage #2: methyl-4-bromo-2-butenoate With N,N,N,N,-tetramethylethylenediamine; cobalt(II) bromide In tetrahydrofuran at -20 - 0℃; Inert atmosphere; Stage #3: With ammonium chloride In tetrahydrofuran; water	93%

: 14243-64-2
(triphenylphosphine)gold(I) chloride

: 367-23-7
1,2,4-trifluorobenzene

: 2,3,6-trifluorophenyl(triphenylphosphine)gold(I)

Conditions

Conditions	Yield
With potassium carbonate; silver(l) oxide; Trimethylacetic acid In N,N-dimethyl-formamide at 50℃; for 16h; Inert atmosphere;	92%

: 3857-83-8
2-naphthyl triflate

: 367-23-7
1,2,4-trifluorobenzene

: 2-(1',3',4'-trifluorophenyl)naphthalene

Conditions

Conditions	Yield
With bis(1,5-cyclooctadiene)nickel (0); 18-crown-6 ether; 2-[bis((3,5-dimethyl-4-methoxyphenyl)phosphino)phenyl]ether; isopropylmagnesium chloride In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane at 40℃; for 2h;	91%

: 502-97-6
glycolide

: 367-23-7
1,2,4-trifluorobenzene

: 209995-38-0
(2,4,5-trifluorophenyl)acetic acid

Conditions

Conditions	Yield
With aluminum (III) chloride at 70℃; for 12h;	90.4%

: 367-23-7
1,2,4-trifluorobenzene

: 3-hydroxy-3-(2,3,6-trifluorophenyl)butan-2-one

Conditions

Conditions	Yield
With n-butyllithium; diisopropylamine In tetrahydrofuran at -70 - -45℃; for 0.5h;	90.2%

: 124-38-9
carbon dioxide

: 367-23-7
1,2,4-trifluorobenzene

: 2358-29-4
2,3,6-trifluorobenzoic acid

Conditions

Conditions	Yield
Stage #1: carbon dioxide With AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); potassium hydroxide In tetrahydrofuran at 20℃; under 1125.11 Torr; for 0.25h; Stage #2: 1,2,4-trifluorobenzene In tetrahydrofuran at 20℃; under 1125.11 Torr; for 12h; Stage #3: With hydrogenchloride In tetrahydrofuran; water regioselective reaction;	88%
Stage #1: carbon dioxide; 1,2,4-trifluorobenzene With cesium hydroxide; (hydroxido){N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene}copper(I) In tetrahydrofuran at 65℃; for 8h; Inert atmosphere; Stage #2: With hydrogenchloride In water Inert atmosphere; regioselective reaction;	85%
Stage #1: 1,2,4-trifluorobenzene With n-butyllithium In tetrahydrofuran at -70℃; Metallation; Stage #2: carbon dioxide In tetrahydrofuran Carboxylation;

: 367-23-7
1,2,4-trifluorobenzene

: 768-60-5
4-methoxyphenylacetylen

: 854266-72-1
1,2-difluoro-4-((4-methoxyphenyl)ethynyl)benzene

Conditions

Conditions	Yield
With butyl magnesium bromide; sodium methylate; sodium; calcium hydroxide In tetrahydrofuran at 0℃; for 0.0916667h; Sonogashira Cross-Coupling; Inert atmosphere; Reflux;	88%

: 367-23-7
1,2,4-trifluorobenzene

: 75-36-5
acetyl chloride

: 129322-83-4
2',4',5'-trifluoroacetophenone

Conditions

Conditions	Yield
With aluminium trichloride at 80℃; for 24h; Acylation;	87%
With aluminium trichloride 1.) 50 deg C, 1 h, 2.) 80 deg C, 22 h; Yield given. Multistep reaction;
Acetylation;

: 367-23-7
1,2,4-trifluorobenzene

: 582-52-5
1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

: 1,2:5,6-di-O-isopropylidene-3-O-(2',5'-difluoro)benzene-α-D-glucofuranoside

Conditions

Conditions	Yield
With potassium hexamethylsilazane In N,N-dimethyl-formamide; toluene at 0 - 20℃; for 16h; Inert atmosphere; Schlenk technique; regioselective reaction;	86%

: 120-72-9
indole

: 367-23-7
1,2,4-trifluorobenzene

: 1448804-18-9
1-(2,5-difluorophenyl)-1H-indole

Conditions

Conditions	Yield
With sodium hydroxide In N,N-dimethyl-formamide at 70℃; Sealed tube; Schlenk technique; Inert atmosphere;	85%

: 79-36-7
dichloroacethyl chloride

: 367-23-7
1,2,4-trifluorobenzene

: 375369-29-2
2,4,5-trifluoromandelic acid

Conditions

Conditions	Yield
Stage #1: dichloroacethyl chloride; 1,2,4-trifluorobenzene; aluminum (III) chloride at 60℃; Stage #2: With sodium hydroxide; water at 60℃; Stage #3: With hydrogenchloride In water at 0 - 20℃; pH=1;	84%

: 1458-98-6
2-methyl-3-bromo-1-propene

: 367-23-7
1,2,4-trifluorobenzene

: 1,2,4-trifluoro-3-(2-methylprop-1-en-1-yl)benzene

Conditions

Conditions	Yield
With [Cu(1,3-di-iso-propylimidazolin-2-ylidene)(Cl)]; sodium t-butanolate In tetrahydrofuran at 60℃; for 12h; Inert atmosphere; Schlenk technique; Glovebox;	84%

: 626-55-1
3-Bromopyridine

: 367-23-7
1,2,4-trifluorobenzene

: 3-(2,3,6-trifluorophenyl)pyridine

Conditions

Conditions	Yield
With palladium 10% on activated carbon; potassium acetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; regioselective reaction;	84%
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; regioselective reaction;	72%

: 367-23-7
1,2,4-trifluorobenzene

: 66684-57-9
1,2,5-trifluoro-3-nitrobenzene

Conditions

Conditions	Yield
With 2CF3SO3H-B(OSO2CF3)3; nitric acid at 20℃; for 3h;	83%

: 623-13-2
4-methylphenyl methylsulfide

: 367-23-7
1,2,4-trifluorobenzene

: 1422961-31-6
2,3,6-trifluoro-4′-methyl-1,1′-biphenyl

Conditions

Conditions	Yield
With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl) palladium(II) dichloride; 2,2,6,6-tetramethylpiperidinylzinc chloride lithium chloride complex In tetrahydrofuran at 80℃; for 7h; Inert atmosphere; regioselective reaction;	83%

: 367-23-7
1,2,4-trifluorobenzene

: 73183-34-3
bis(pinacol)diborane

: 2-(2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
With bis(1,3-dimesityl-1H-imidazol-2(3H)-ylidene)nickel(0); C32H41O6P2Rh; cesium fluoride In 1,3,5-trimethyl-benzene at 25℃; for 6h; Irradiation; Inert atmosphere; Sealed tube; regioselective reaction;	82%

: 367-23-7
1,2,4-trifluorobenzene

: C54H47B2ClN4

: C60H50B2ClF3N4

Conditions

Conditions	Yield
at 80℃; for 4h; Inert atmosphere; regioselective reaction;	82%

1,2,4-Trifluorobenzene Chemical Properties

The Molecular formula of 1,2,4-Trifluorobenzene(367-23-7) : C₆H₃F₃

The Molecular Weight of 1,2,4-Trifluorobenzene(367-23-7) : 132.08
Molecular Structure :

Boiling point : 88-91°C

Density: 1.264

Flash point: 4°C

Refractive index: 1.422-1.424

1,2,4-Trifluorobenzene Toxicity Data With Reference

1,2,4-Trifluorobenzene(367-23-7) is highly flammable.

1,2,4-Trifluorobenzene(367-23-7) is irritating to eyes、respiratory system and skin.

1,2,4-Trifluorobenzene Safety Profile

Keep 1,2,4-Trifluorobenzene(367-23-7) away from sources of ignition.

The Hazard Codes of 1,2,4-Trifluorobenzene(367-23-7) ： F, Xi
WGK Germany:3
RIDADR:UN 1993 3/PG 2
Hazard Note:Flammable
HazardClass:3

1,2,4-Trifluorobenzene Specification

Stability:Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities:Strong oxidizing agents.
Decomposition:Carbon monoxide, carbon dioxide, HYDROGEN FLUORIDE.
Combustion Products：Fire may produce irritating, corrosive and/or toxic gases.

Product Name

1,2,4-Trifluorobenzene

Synthetic route

1,2,4-Trifluorobenzene Chemical Properties

1,2,4-Trifluorobenzene Toxicity Data With Reference

1,2,4-Trifluorobenzene Safety Profile

1,2,4-Trifluorobenzene Specification

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