2,7-Dichlorofluorene supplier

Name
2,7-Dichlorofluorene
EINECS 676-989-3
CAS No. 7012-16-0
Article Data29
CAS DataBase
Density 1.365 g/cm³
Solubility
Melting Point 126-128 °C
Formula C₁₃H₈Cl₂
Boiling Point 370.7 °C at 760 mmHg
Molecular Weight 235.113
Flash Point 185.3 °C
Transport Information
Appearance Off-white solid
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols Xi
Synonyms Fluorene,2,7-dichloro- (6CI,7CI,8CI);2,7-Dichloro-9H-fluorene;NSC 73077;
PSA 0.00000
LogP 4.56460

Synthetic route

: 86-73-7
9H-fluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With hydrogenchloride; N-chloro-succinimide In acetonitrile Heating;	90%
With chlorine In acetic acid at 35 - 45℃; for 15h;	48%
With chlorine; acetic acid at 40℃; for 2h;	40.9%

: 67-56-1
methanol

: 888-01-7
2,7-Dichlor-9-diazofluoren

A: 56486-03-4
2,2',7,7'-tetrachloro-9-fluorenyl dimer

B: 7012-16-0
2,7-dichloro-9H-fluorene

C: 2,7-dichlorofluorenyl methyl ether

Conditions

Conditions	Yield
for 0.783333h; Irradiation;	A n/a B 5% C 90%
With 11H-Benzo[b]fluoren-11-one In acetonitrile for 0.833333h; Irradiation;	A 22% B 9% C 26%

...Expand

: 6297-11-6
2,7-dichlorofluorenone

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With iodine; magnesium In methanol at 20℃; for 1h;	85%
With phosphorus; hydrogen iodide at 115 - 120℃;

: 106112-42-9
2,7-dichloro-3,6-di-t-butylfluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With aluminium trichloride In benzene at 50℃; for 0.5h;	37%

: 86-73-7
9H-fluorene

A: 2523-44-6
2-chloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With chloroform; chlorine at 0 - 5℃;

: 58066-92-5
2,7,9,9-tetrachloro-9H-fluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With hydrogenchloride; zinc; benzene

: 16433-88-8
2,7-dibromo-9H-fluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With copper(l) chloride; copper dichloride Halogen exchange reaction;

: 86-73-7
9H-fluorene

: 7782-50-5
chlorine

A: 2523-44-6
2-chloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

...Expand

: 86-73-7
9H-fluorene

: 67-66-3
chloroform

: 7782-50-5
chlorine

A: 2523-44-6
2-chloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
at 0 - 5℃;

...Expand

: 86-73-7
9H-fluorene

: 7647-18-9
antimonypentachloride

: 7782-50-5
chlorine

A: 2523-44-6
2-chloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
verschiedene Loesungsmittel, bei verschiedenen Temperaturen;

...Expand

: 86-73-7
9H-fluorene

: 7553-56-2
iodine

: 7782-50-5
chlorine

A: 2523-44-6
2-chloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
verschiedene Loesungsmittel, bei verschiedenen Temperaturen;

...Expand

: 86-73-7
9H-fluorene

: 67-66-3
chloroform

: 7782-50-5
chlorine

A: 2523-44-6
2-chloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

C: 7061-81-6
2,4,7-trichlorofluorene

Conditions

Conditions	Yield
at 0 - 5℃;

...Expand

: 6297-11-6
2,7-dichlorofluorenone

: 10034-85-2
hydrogen iodide

red phosphorus: red phosphorus

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
at 115 - 120℃;

...Expand

: 19099-48-0
1,1-bis(4-t-butylphenyl)methane

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 54 percent / periodic acid, 98percent H2SO4 / H2O 2: 95 percent / copper / 4 h / 230 °C 3: 84 percent / iron, chlorine / CCl4 / 0.5 h / 30 °C 4: 37 percent / AlCl3 / benzene / 0.5 h / 50 °C View Scheme

: 58775-07-8
3,6-di-tert-butyl-9H-fluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 84 percent / iron, chlorine / CCl4 / 0.5 h / 30 °C 2: 37 percent / AlCl3 / benzene / 0.5 h / 50 °C View Scheme

: 58775-15-8
3,6-di-tert-butyl-9H-fluoren-9-one

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 93 percent / sodium borohydride / ethanol / 0.5 h / Heating 2: 90 percent / hydroiodic acid / acetic acid / 2 h / Heating 3: 84 percent / iron, chlorine / CCl4 / 0.5 h / 30 °C 4: 37 percent / AlCl3 / benzene / 0.5 h / 50 °C View Scheme

: 106112-40-7
3,6-di-t-butyl-9-fluorenol

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 90 percent / hydroiodic acid / acetic acid / 2 h / Heating 2: 84 percent / iron, chlorine / CCl4 / 0.5 h / 30 °C 3: 37 percent / AlCl3 / benzene / 0.5 h / 50 °C View Scheme

: 106112-39-4
2,2'-diiodo-4,4'-di(tert-butyl)diphenylmethane

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 95 percent / copper / 4 h / 230 °C 2: 84 percent / iron, chlorine / CCl4 / 0.5 h / 30 °C 3: 37 percent / AlCl3 / benzene / 0.5 h / 50 °C View Scheme

: 96463-26-2
2-bromo-7-chloro-9H-fluoren-9-one

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: PCl5 / 180 °C 2: benzene; zinc; aqueous HCl View Scheme

: 99515-75-0
2-bromo-9,9-dichlorofluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: benzene 2: acetic acid; Na2Cr2O7 3: PCl5 / 180 °C 4: benzene; zinc; aqueous HCl View Scheme
Multi-step reaction with 3 steps 1: benzene 2: PCl5 / 180 °C 3: benzene; zinc; aqueous HCl View Scheme

: 96463-27-3
2-bromo-7,9,9-trichloro-fluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: acetic acid; Na2Cr2O7 2: PCl5 / 180 °C 3: benzene; zinc; aqueous HCl View Scheme
Multi-step reaction with 2 steps 1: PCl5 / 180 °C 2: benzene; zinc; aqueous HCl View Scheme

: 54983-24-3
2,7-dibromo-9,9-dichloro-fluorene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: PCl5 2: benzene; zinc; aqueous HCl View Scheme

: 96462-70-3
(2-bromo-5-chlorophenyl)(3-chlorophenyl)methanol

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique 1.2: 0 - 20 °C / Inert atmosphere; Schlenk technique 2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 2.2: -78 - 20 °C / Inert atmosphere; Schlenk technique 3.1: tetrahydrothiophene gold(III) bromide; [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid / methanol; chloroform / 48 h / 27 °C / Schlenk technique; Inert atmosphere; Sealed tube View Scheme

Yield

Multi-step reaction with 3 steps
1.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique
1.2: 0 - 20 °C / Inert atmosphere; Schlenk technique
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique
2.2: -78 - 20 °C / Inert atmosphere; Schlenk technique
3.1: tetrahydrothiophene gold(III) bromide; [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid / methanol; chloroform / 48 h / 27 °C / Schlenk technique; Inert atmosphere; Sealed tube
View Scheme

: 96583-68-5
1-bromo-4-chloro-2-(3-chlorobenzyl)benzene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 1.2: -78 - 20 °C / Inert atmosphere; Schlenk technique 2.1: tetrahydrothiophene gold(III) bromide; [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid / methanol; chloroform / 48 h / 27 °C / Schlenk technique; Inert atmosphere; Sealed tube View Scheme

: [4-chloro-2-(3-chlorobenzyl)phenyl](trimethyl)silane

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid; tetrahydrothiophene gold(III) bromide In methanol; chloroform at 27℃; for 48h; Schlenk technique; Inert atmosphere; Sealed tube;

: 108-37-2
1-bromo-3-chlorobenzene

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 1.2: -78 - 20 °C / Inert atmosphere; Schlenk technique 2.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique 2.2: 0 - 20 °C / Inert atmosphere; Schlenk technique 3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 3.2: -78 - 20 °C / Inert atmosphere; Schlenk technique 4.1: tetrahydrothiophene gold(III) bromide; [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid / methanol; chloroform / 48 h / 27 °C / Schlenk technique; Inert atmosphere; Sealed tube View Scheme

Yield

Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique
1.2: -78 - 20 °C / Inert atmosphere; Schlenk technique
2.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique
2.2: 0 - 20 °C / Inert atmosphere; Schlenk technique
3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique
3.2: -78 - 20 °C / Inert atmosphere; Schlenk technique
4.1: tetrahydrothiophene gold(III) bromide; [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid / methanol; chloroform / 48 h / 27 °C / Schlenk technique; Inert atmosphere; Sealed tube
View Scheme

: 174265-12-4
2-bromo-5-chlorobenzaldehyde

: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 1.2: -78 - 20 °C / Inert atmosphere; Schlenk technique 2.1: trifluoroacetic acid / dichloromethane / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique 2.2: 0 - 20 °C / Inert atmosphere; Schlenk technique 3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 3.2: -78 - 20 °C / Inert atmosphere; Schlenk technique 4.1: tetrahydrothiophene gold(III) bromide; [bis(acetoxy)iodo]benzene; (R)-10-camphorsulfonic acid / methanol; chloroform / 48 h / 27 °C / Schlenk technique; Inert atmosphere; Sealed tube View Scheme

Yield

: 86-73-7
9H-fluorene

A: 2,5-dichloro-9H-fluorene

B: 7012-16-0
2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
With chlorine; acetic acid at 40 - 42℃;

: 109-65-9
1-bromo-butane

: 7012-16-0
2,7-dichloro-9H-fluorene

: 2,7-dichloro-9,9-dibutylfluorene

Conditions

Conditions	Yield
Stage #1: 2,7-dichloro-9H-fluorene With tetra-(n-butyl)ammonium iodide; sodium hydroxide In water at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: 1-bromo-butane In water at 70℃; for 12h; Inert atmosphere;	97%
With tetrabutylammomium bromide; potassium hydroxide In toluene for 16h; Inert atmosphere;	90%

: 7012-16-0
2,7-dichloro-9H-fluorene

: 79-04-9
chloroacetyl chloride

: 2-chloro-1-(2,7-dichloro-9H-fluoren-4-yl)-ethan-1-one

Conditions

Conditions	Yield
With aluminum (III) chloride In dichloromethane at -5 - 0℃;	94%
With aluminum (III) chloride In dichloromethane at 0 - 5℃; Friedel-Crafts Acylation;	94%
With aluminum (III) chloride In dichloromethane at 20℃; for 3h; Cooling;	87%
With aluminum (III) chloride In dichloromethane at 0 - 5℃; for 8h; Large scale;	297 kg

: 7012-16-0
2,7-dichloro-9H-fluorene

: 108-98-5
thiophenol

: 2,7-dichloro-9-phenylthiofluorene

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; potassium hydroxide In water; dimethyl sulfoxide at 20℃; for 2h; Schlenk technique; Sealed tube; Inert atmosphere; Green chemistry;	94%

: 7012-16-0
2,7-dichloro-9H-fluorene

: 6297-11-6
2,7-dichlorofluorenone

Conditions

Conditions	Yield
With copper(II) choride dihydrate; 4,7-bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-1,10-phenanthroline; oxygen; sodium hydroxide In water at 50℃; for 16h; Schlenk technique;	92%
With C38H60N2O12; nickel diacetate; cesium fluoride In water at 100℃; for 8h;	92%
With tert.-butylhydroperoxide; copper(II) acetate monohydrate In water at 80℃; for 8h;	90%

: 7012-16-0
2,7-dichloro-9H-fluorene

: 109-94-4
formic acid ethyl ester

: 122237-22-3
2,7-dichloro-9-(hydroxymethylene)fluorene

Conditions

Conditions	Yield
With potassium ethoxide In diethyl ether for 3h; Heating;	92%

: 75-21-8
oxirane

: 7012-16-0
2,7-dichloro-9H-fluorene

A: 9-(2-hydroxyethyl)-2,7-dichlorofluorene

B: 9,9-bis(2-hydroxyethyl)-2,7-dichlorofluorene

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; diethyl ether; hexane -40 deg C then rt., 10 h;	A 8% B 78%

...Expand

: 7012-16-0
2,7-dichloro-9H-fluorene

: 100-52-7
benzaldehyde

: 23000-29-5
9-benzylidene-2,7-dichloro-9H-fluorene

Conditions

Conditions	Yield
Stage #1: 2,7-dichloro-9H-fluorene With potassium tert-butylate In tert-butyl alcohol at 40℃; for 0.5h; Stage #2: benzaldehyde In tert-butyl alcohol at 40 - 50℃; for 3h;	74%
With sodium ethanolate

: 371-42-6
4-Fluorothiophenol

: 7012-16-0
2,7-dichloro-9H-fluorene

: 2,7-dichloro-9-((4-fluorophenyl)thio)-9H-fluorene

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; potassium hydroxide In water; dimethyl sulfoxide at 20℃; for 2h; Schlenk technique; Sealed tube; Inert atmosphere; Green chemistry;	63%

: 7012-16-0
2,7-dichloro-9H-fluorene

: 73183-34-3
bis(pinacol)diborane

: 467219-11-0
2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-fluorene

Conditions

Conditions	Yield
With p-phenylpyridine; sodium methylate In acetonitrile at 20℃; for 12h; Sealed tube; Inert atmosphere; Irradiation;	62%

: 7012-16-0
2,7-dichloro-9H-fluorene

: C15H16

: C41H36

Conditions

Conditions	Yield
In diethyl ether Cooling with ice; Reflux;	37%

: 7012-16-0
2,7-dichloro-9H-fluorene

: C15H16

: C41H32Cl4

Conditions

Conditions	Yield
In diethyl ether Cooling with ice; Reflux;	35%

: 7012-16-0
2,7-dichloro-9H-fluorene

: C20H26

: C46H42Cl4

Conditions

Conditions	Yield
In diethyl ether for 24h; Cooling with ice;	32%

: 120-57-0
piperonal

: 7012-16-0
2,7-dichloro-9H-fluorene

: 80918-82-7
2,7-dichloro-9-piperonylidene-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 3132-99-8
m-bromobenzoic aldehyde

: 7012-16-0
2,7-dichloro-9H-fluorene

: 80918-77-0
9-(3-bromo-benzylidene)-2,7-dichloro-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: bis-(2,7-dichloro-fluoren-9-yliden)-ethane

Conditions

Conditions	Yield
With ethanol; aromatic aldehyde; sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 7061-81-6
2,4,7-trichlorofluorene

Conditions

Conditions	Yield
With chloroform; iodine; chlorine

: 7012-16-0
2,7-dichloro-9H-fluorene

: 4-bromo-2,7-dichloro-fluorene

Conditions

Conditions	Yield
With chloroform; bromine; iron

: 7012-16-0
2,7-dichloro-9H-fluorene

: 104-88-1
4-chlorobenzaldehyde

: 4364-35-6
2,7-dichloro-9-(4-chloro-benzylidene)-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 623-27-8
terephthalaldehyde,

: 80918-86-1
9-(4-Aldehydobenzylidene)-2,7-dichlorofluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 623-27-8
terephthalaldehyde,

: 80918-88-3
2,2',7,7'-tetrachloro-terephthalal-9,9'-difluorene

Conditions

Conditions	Yield
With ethanol; sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 89-98-5
2-chloro-benzaldehyde

: 80918-75-8
2,7-dichloro-9-(2-chloro-benzylidene)-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 83-38-5
2,6-dichlorobenzaldehyde

: 2,7-dichloro-9-(2,6-dichloro-benzylidene)-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 99-61-6
3-nitro-benzaldehyde

: 4364-36-7
2,7-dichloro-9-(3-nitro-benzylidene)-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

: 7012-16-0
2,7-dichloro-9H-fluorene

: 555-16-8
4-nitrobenzaldehdye

: 80918-80-5
2,7-dichloro-9-(4-nitro-benzylidene)-fluorene

Conditions

Conditions	Yield
With sodium ethanolate

2,7-Dichlorofluorene Chemical Properties

Product Name: 2,7-Dichlorofluorene (CAS NO.7012-16-0)

Molecular Formula: C₁₃H₈Cl₂
Molecular Weight: 235.11g/mol
Mol File: 7012-16-0.mol
Melting Point: 126-128
Boiling point: 370.7 °C at 760 mmHg
Flash Point: 185.3 °C
Density: 1.365 g/cm³
Surface Tension: 50.2 dyne/cm
Enthalpy of Vaporization: 59.34 kJ/mol
Vapour Pressure: 2.32E-05 mmHg at 25°C
XLogP3-AA: 4.9
H-Bond Donor: 0
H-Bond Acceptor: 0
Structure Descriptors of 2,7-Dichlorofluorene (CAS NO.7012-16-0):
IUPAC Name: 2,7-Dichloro-9H-fluorene
Canonical SMILES: C1C2=C(C=CC(=C2)Cl)C3=C1C=C(C=C3)Cl
InChI: InChI=1S/C13H8Cl2/c14-10-1-3-12-8(6-10)5-9-7-11(15)2-4-13(9)12/h1-4,6-7H,5H2
InChIKey: SDPURBHAHVFTGX-UHFFFAOYSA-N
Product Categories: Electronic Chemicals

2,7-Dichlorofluorene Safety Profile

Safety Information of 2,7-Dichlorofluorene (CAS NO.7012-16-0):
Hazard Codes: Xi
Safety Statements: 22-24/25
22: Do not breathe dust
24: Avoid contact with skin
25: Avoid contact with eyes
Hazard Note: Irritant

2,7-Dichlorofluorene Specification

2,7-Dichlorofluorene , its CAS NO. is 7012-16-0, the synonym is 2,7-Dichloro-9H-fluorene .

Product Name

2,7-Dichlorofluorene

Synthetic route

2,7-Dichlorofluorene Chemical Properties

2,7-Dichlorofluorene Safety Profile

2,7-Dichlorofluorene Specification

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