2-Aminobenzenethiol supplier

Name
2-Aminobenzenethiol
EINECS 205-277-3
CAS No. 137-07-5
Article Data101
CAS DataBase
Density 1.2 g/cm³
Solubility insoluble in water
Melting Point 23 °C
Formula C₆H₇NS
Boiling Point 234.9 °C at 760 mmHg
Molecular Weight 125.194
Flash Point 95.8 °C
Transport Information UN 1760 8/PG 3
Appearance clear yellow to amber liquid
Safety 26-36/37/39-45-60-61-25-27
Risk Codes 22-34-50/53-37-20/21/22
Molecular Structure
Hazard Symbols C,N
Synonyms NSC 106635;o-Aminobenzenethiol;o-Aminophenyl mercaptan;o-Aminothiophenol;o-Mercaptoaniline;a-Aminothiophenol;Benzenethiol,2-amino-;Benzenethiol,o-amino- (6CI,8CI);1-Amino-2-mercaptobenzene;2-Amino-1-mercaptobenzene;2-Aminophenyl mercaptan;2-Mercaptoaniline;2-Thioaniline;
PSA 64.82000
LogP 2.13870

Synthetic route

: 615-43-0
2-iodophenylamine

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With copper(ll) sulfate pentahydrate; ethane-1,2-dithiol; potassium hydroxide In water; dimethyl sulfoxide at 90℃; for 20h; Inert atmosphere;	99%

: 95-16-9
1,3-Benzothiazole

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; iodine In water; dimethyl sulfoxide at 60℃;	98%
With potassium hydroxide at 110℃; for 24h; Reagent/catalyst;	87%
With iodine; potassium hydroxide In water; dimethyl sulfoxide at 100℃;	82%

: 1141-88-4
2-Aminophenyl disulfide

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With indium; ammonium chloride In ethanol for 2h; Reduction; Heating;	96%
With sodium tetrahydroborate; lithium chloride In tetrahydrofuran at 0 - 35℃;	93%
With magnesium In methanol for 2h; Ambient temperature;	85%

: 86333-20-2
2-(2-aminophenylthio)-4-phenyl-2,3-dihydro-1,5-benzothiazepine

A: 612-96-4
2-Phenylquinoline

B: 137-07-5
2-amino-benzenethiol

C: 1141-88-4
2-Aminophenyl disulfide

Conditions

Conditions	Yield
In toluene for 4h; Heating;	A 95% B n/a C n/a

...Expand

: 2987-53-3
2-(Methylthio)aniline

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With hydrogen bromide In water at 30℃; for 2h; Temperature; Inert atmosphere;	92.7%

: 1141-88-4
2-Aminophenyl disulfide

: 587-88-2
ethyl 2-(4-fluorophenyl)acetate

A: 100638-27-5
2-(4-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide; N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 92% B n/a

...Expand

: 1155-00-6
bis(2-nitrophenyl)disulfide

A: 4875-10-9
2-nitrothiophenol

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium tetrahydroborate; zirconium(IV) chloride In tetrahydrofuran at 35℃; for 0.5h; Reduction;	A 10% B 90%
With sodium tetrahydroborate; zirconium(IV) chloride In tetrahydrofuran at 35℃; for 0.166667h; Reduction;	A 80% B 20%

: 23786-14-3
4-methoxy-phenyl acetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 92552-87-9
2-(4-methoxy-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide; N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 88% B n/a

...Expand

: 101-41-7
benzeneacetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 38533-19-6
3,4-dihydro-2-phenyl-2H-1,4-benzothiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 86% B n/a
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h; other methyl or ethyl aryl- or pyridylacetates;

...Expand

: 2-(2-amino-phenyldisulfanyl)-pyridin-3-ylamine

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium tetrahydroborate; zirconium(IV) chloride In tetrahydrofuran at 35℃; for 0.25h; Reduction;	85%

: 2876-78-0
methyl 1-naphthylacetate

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-98-7
2-Naphthalen-1-yl-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 82% B n/a

...Expand

: 149-30-4
2-Mercaptobenzothiazole

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With potassium hydroxide at 110℃; for 24h; Reagent/catalyst;	82%

: 52449-43-1
(4-chloro-phenyl)-acetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 137-07-5
2-amino-benzenethiol

B: 4652-24-8
2-(4-chlorophenyl)-1,4-benzothiazin-3-one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A n/a B 81%

...Expand

: 19626-36-9
methyl 2-(3-bromo-4-methoxyphenyl)acetate

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-96-5
2-(3-Bromo-4-methoxy-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 80% B n/a

...Expand

: 57486-68-7
methyl (2-chlorophenyl)acetate

: 1141-88-4
2-Aminophenyl disulfide

A: 137-07-5
2-amino-benzenethiol

B: 58553-47-2
2-(2-chloro-phenyl)-4H-benzo[1,4]thiazin-3-one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A n/a B 79%

...Expand

: 136-95-8
2-amino-benzthiazole

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With potassium hydroxide; water In ethylene glycol at 125℃; for 15h;	78%
With potassium hydroxide at 110℃; for 24h; Reagent/catalyst;	75%
With hydroxide

: 14062-19-2
p-tolylacetic acid ethyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-92-1
2-(4-methylphenyl)-1,4-benzothiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 77% B n/a

...Expand

: 326-59-0
benzo[1,3]dioxol-5-yl-acetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-97-6
2-Benzo[1,3]dioxol-5-yl-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 73% B n/a

...Expand

: 39931-77-6
pyridin-3-yl-acetic acid ethyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 131603-00-4
2-(3-pyridyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 72% B n/a

...Expand

: 18066-68-7
ethyl 3,4-dimethoxyphenylacetate

: 1141-88-4
2-Aminophenyl disulfide

A: 117838-86-5
2-(3,4-Dimethoxy-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 71% B n/a

...Expand

: 113372-40-0
2,3-dihydro-3-methoxycarbonyl-2-benzothiazolecarbonitrile

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With potassium hydroxide In ethanol for 2h; Heating;	70%
With potassium hydroxide In ethanol for 2h; Heating;	70%

: 149-30-4
2-Mercaptobenzothiazole

A: 2203-24-9
N,N',N''-triaminoguanidine

B: 137-07-5
2-amino-benzenethiol

C: 615-21-4
2-hydrazono-2,3-dihydro-1,3-benzothiazole

D: 1141-88-4
2-Aminophenyl disulfide

Conditions

Conditions	Yield
With hydrazine hydrate at 105 - 110℃; for 76h; Product distribution; Mechanism; also reaction with ethylenediamine, propylenediamine; other temp. (150 deg C);	A n/a B 70% C 20% D n/a
With hydrazine hydrate at 105 - 110℃; for 76h;	A n/a B 70% C 20% D n/a

...Expand

: 2739-98-2
ethyl 2-(pyridinyl-2)acetate

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-99-8
2-(2-pyridyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 69% B n/a

...Expand

: 16216-94-7
methyl 2-(4-isopropylphenyl)acetate

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-93-2
2-(4-Isopropyl-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 69% B n/a

...Expand

: 62451-84-7
(3-trifluoromethyl-phenyl)-acetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-94-3
2-(3-Trifluoromethyl-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 65% B n/a

...Expand

: 95-16-9
1,3-Benzothiazole

A: 137-07-5
2-amino-benzenethiol

B: 1141-88-4
2-Aminophenyl disulfide

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate In water at 100℃;	A 63% B 33%

: 6325-92-4
2-(benzylsulfanyl)aniline

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With titanium(III) chloride; lithium In tetrahydrofuran for 20h; Heating;	55%

: 77053-20-4
2-(2-propen-1-ylsulfanyl)aniline

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With titanium(III) chloride; lithium In tetrahydrofuran at 25℃; for 2h;	47%

: 95479-50-8
2,3-dihydro-3-(4-methylbenzoyl)-2-benzothiazolecarbonitrile

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With potassium hydroxide In ethanol for 2h; Heating;	46%

: 108-94-1
cyclohexanone

: 137-07-5
2-amino-benzenethiol

: 182-53-6
3H-spiro{benzothiazole-2,1'-cyclohexane}

Conditions

Conditions	Yield
With trifluoroacetic acid at 80℃; for 16h; Reagent/catalyst;	100%
In toluene Heating;	93.8%
With aluminum oxide In neat (no solvent) at 20℃; for 0.5h; Inert atmosphere;	92%

: 100-52-7
benzaldehyde

: 137-07-5
2-amino-benzenethiol

: 883-93-2
2-Phenylbenzothiazole

Conditions

Conditions	Yield
With Yb/MCM-41 molecular sieve In ethanol at 80℃; for 4h; Concentration; Temperature;	100%
Stage #1: benzaldehyde; 2-amino-benzenethiol With oxygen; scandium tris(trifluoromethanesulfonate) In tetrahydrofuran; water for 3h; Cycloaddition; Stage #2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone for 0.25h; Oxidation;	99%
With 1-pentyl-3-methylimidazolium bromide for 0.05h; microwave irradiation;	99%

: 75-36-5
acetyl chloride

: 137-07-5
2-amino-benzenethiol

: 120-75-2
2-Methylbenzothiazole

Conditions

Conditions	Yield
In toluene at 20℃; for 0.25h;	100%
In neat (no solvent) for 4h; Time; Temperature; Green chemistry;	91%
In toluene at 20℃; for 0.416667h;	85%

: 137-07-5
2-amino-benzenethiol

: 67-64-1
acetone

: 25111-89-1
2,2-dimethyl-2,3-dihydro-benzothiazole

Conditions

Conditions	Yield
at 0℃; for 2h; gas/solid reaction;	100%
Stage #1: 2-amino-benzenethiol; acetone In neat (no solvent) at 50℃; for 1h; Green chemistry; Stage #2: With o-benzenedisulfonimide In neat (no solvent) at 50℃; for 48h; Green chemistry;	87%
With aluminum oxide at 20℃; for 0.5h;	84%

: 137-07-5
2-amino-benzenethiol

: 1141-88-4
2-Aminophenyl disulfide

Conditions

Conditions	Yield
With trifluoroacetic acid In dimethyl sulfoxide at 80℃; for 16h; Reagent/catalyst;	100%
With imino urea In methanol for 0.0833333h; Ambient temperature;	99%
With nanophase manganese (VII) oxide coated clay (NM7O coated clay) In chloroform at 20℃;	99%

: 100-52-7
benzaldehyde

: 137-07-5
2-amino-benzenethiol

: 31230-83-8
2-Phenylbenzothiazolin

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 60℃; for 2h; Molecular sieve;	100%
With yttrium(III) chloride In ethanol for 0.5h; Time; Reflux; Inert atmosphere;	98%
In ethanol for 0.666667h; Ambient temperature;	94%

: 104-88-1
4-chlorobenzaldehyde

: 137-07-5
2-amino-benzenethiol

: 56048-77-2
2-(4-chlorophenyl)-2,3-dihydrobenzo[d]thiazole

Conditions

Conditions	Yield
In ethanol for 0.666667h; Ambient temperature;	100%

: 75-03-6
ethyl iodide

: 137-07-5
2-amino-benzenethiol

: 13920-91-7
2-(ethylthio)aniline

Conditions

Conditions	Yield
With sodium hydride In acetonitrile at 0℃; for 7h;	100%
With sodium methylate In methanol for 6h; Reflux;	97%
Stage #1: 2-amino-benzenethiol With potassium tert-butylate In ethanol at 0℃; for 0.75h; Stage #2: ethyl iodide In ethanol at 0 - 20℃; for 0.75h; Further stages.;	85%

: 120-46-7
1,3-diphenylpropanedione

: 137-07-5
2-amino-benzenethiol

: 131526-02-8
1-(2-mercaptophenylimino)-1 3-diphenylpropan-3-one

Conditions

Conditions	Yield
With piperidine In ethanol Heating;	100%

: 31357-83-2, 31357-84-3, 39831-17-9
3-chloro-2-phenyl-but-2-enal

: 137-07-5
2-amino-benzenethiol

: 133205-45-5
2-Methyl-3-phenyl-benzo[b][1,4]thiazepine

Conditions

Conditions	Yield
	100%

: 1002-41-1
bis(2-chloroethyl)disulfide

: 137-07-5
2-amino-benzenethiol

: 220597-09-1
1,8-Bis(2-aminophenyl)-1,4,5,8-tetrathiaoctane

Conditions

Conditions	Yield
With potassium hydroxide In methanol for 2h; Heating;	100%

: 93-44-7
2-naphthyl benzoate

: 137-07-5
2-amino-benzenethiol

A: 883-93-2
2-Phenylbenzothiazole

B: 135-19-3
β-naphthol

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 100℃; for 0.75h; Hydrolysis; cyclization; debenzoylation;	A n/a B 100%

...Expand

: 1503-86-2
2-naphthyl pivalate

: 137-07-5
2-amino-benzenethiol

A: 17626-88-9
2-(tert-butyl)benzo[d]thiazole

B: 135-19-3
β-naphthol

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 100℃; for 2h; Hydrolysis; cyclization;	A n/a B 100%

...Expand

: 13031-41-9
4-cyanophenyl acetate

: 137-07-5
2-amino-benzenethiol

A: 120-75-2
2-Methylbenzothiazole

B: 767-00-0
4-cyanophenol

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 100℃; for 0.5h; Hydrolysis; cyclization;	A n/a B 100%

...Expand

: 137-07-5
2-amino-benzenethiol

: 180143-65-1
4-cyanophenyl pivalate

A: 17626-88-9
2-(tert-butyl)benzo[d]thiazole

B: 767-00-0
4-cyanophenol

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 100℃; for 1.5h; Hydrolysis; cyclization;	A n/a B 100%

...Expand

: 24424-99-5
di-tert-butyl dicarbonate

: 137-07-5
2-amino-benzenethiol

: 2-hydroxybenzothiazole

Conditions

Conditions	Yield
copper(II) bis(tetrafluoroborate) at 30 - 33℃; for 1h;	100%

: 19172-47-5
Lawessons reagent

: 137-07-5
2-amino-benzenethiol

: 1253576-24-7
2-(4-methoxyphenyl)-2,3-dihydro-1,3,2-benzothiazaphosphole 2-sulfide

Conditions

Conditions	Yield
at 190℃; for 0.0166667h; Neat (no solvent); Microwave irradiation;	100%

: 615-43-0
2-iodophenylamine

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With copper(ll) sulfate pentahydrate; ethane-1,2-dithiol; potassium hydroxide In water; dimethyl sulfoxide at 90℃; for 20h; Inert atmosphere;	99%

: 95-16-9
1,3-Benzothiazole

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; iodine In water; dimethyl sulfoxide at 60℃;	98%
With potassium hydroxide at 110℃; for 24h; Reagent/catalyst;	87%
With iodine; potassium hydroxide In water; dimethyl sulfoxide at 100℃;	82%

: 1141-88-4
2-Aminophenyl disulfide

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With indium; ammonium chloride In ethanol for 2h; Reduction; Heating;	96%
With sodium tetrahydroborate; lithium chloride In tetrahydrofuran at 0 - 35℃;	93%
With magnesium In methanol for 2h; Ambient temperature;	85%

: 86333-20-2
2-(2-aminophenylthio)-4-phenyl-2,3-dihydro-1,5-benzothiazepine

A: 612-96-4
2-Phenylquinoline

B: 137-07-5
2-amino-benzenethiol

C: 1141-88-4
2-Aminophenyl disulfide

Conditions

Conditions	Yield
In toluene for 4h; Heating;	A 95% B n/a C n/a

...Expand

: 2987-53-3
2-(Methylthio)aniline

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With hydrogen bromide In water at 30℃; for 2h; Temperature; Inert atmosphere;	92.7%

: 1141-88-4
2-Aminophenyl disulfide

: 587-88-2
ethyl 2-(4-fluorophenyl)acetate

A: 100638-27-5
2-(4-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide; N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 92% B n/a

...Expand

: 1155-00-6
bis(2-nitrophenyl)disulfide

A: 4875-10-9
2-nitrothiophenol

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium tetrahydroborate; zirconium(IV) chloride In tetrahydrofuran at 35℃; for 0.5h; Reduction;	A 10% B 90%
With sodium tetrahydroborate; zirconium(IV) chloride In tetrahydrofuran at 35℃; for 0.166667h; Reduction;	A 80% B 20%

: 23786-14-3
4-methoxy-phenyl acetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 92552-87-9
2-(4-methoxy-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide; N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 88% B n/a

...Expand

: 101-41-7
benzeneacetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 38533-19-6
3,4-dihydro-2-phenyl-2H-1,4-benzothiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 86% B n/a
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h; other methyl or ethyl aryl- or pyridylacetates;

...Expand

: 2-(2-amino-phenyldisulfanyl)-pyridin-3-ylamine

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium tetrahydroborate; zirconium(IV) chloride In tetrahydrofuran at 35℃; for 0.25h; Reduction;	85%

: 2876-78-0
methyl 1-naphthylacetate

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-98-7
2-Naphthalen-1-yl-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 82% B n/a

...Expand

: 149-30-4
2-Mercaptobenzothiazole

: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With potassium hydroxide at 110℃; for 24h; Reagent/catalyst;	82%

: 52449-43-1
(4-chloro-phenyl)-acetic acid methyl ester

: 1141-88-4
2-Aminophenyl disulfide

A: 137-07-5
2-amino-benzenethiol

B: 4652-24-8
2-(4-chlorophenyl)-1,4-benzothiazin-3-one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A n/a B 81%

...Expand

: 19626-36-9
methyl 2-(3-bromo-4-methoxyphenyl)acetate

: 1141-88-4
2-Aminophenyl disulfide

A: 131602-96-5
2-(3-Bromo-4-methoxy-phenyl)-4H-benzo[1,4]thiazin-3-one

B: 137-07-5
2-amino-benzenethiol

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 0.333333h;	A 80% B n/a

...Expand

2-Aminobenzenethiol Chemical Properties

IUPAC Name: 2-Aminobenzenethiol
Canonical SMILES: C1=CC=C(C(=C1)N)S
InChI: InChI=1S/C6H7NS/c7-5-3-1-2-4-6(5)8/h1-4,8H,7H2
InChIKey: VRVRGVPWCUEOGV-UHFFFAOYSA-N
Molecular Weight: 125.19148 [g/mol]
Molecular Formula: C₆H₇NS
XLogP3-AA: 1.4
H-Bond Donor: 1
H-Bond Acceptor: 1
EINECS: 205-277-3
Water Solubility: INSOLUBLE
Sensitive: Stench
Appearance: clear yellow to amber liquid
Melting Point: 23 °C
Index of Refraction: 1.663
Molar Refractivity: 38.66 cm³
Molar Volume: 104.3 cm³
Surface Tension: 53 dyne/cm
Density: 1.2 g/cm³
Flash Point: 95.8 °C
Enthalpy of Vaporization: 47.16 kJ/mol
Boiling Point: 234.9 °C at 760 mmHg
Vapour Pressure: 0.0517 mmHg at 25 °C
Product Categories of 2-Aminobenzenethiol (CAS NO.137-07-5): Phenol & Thiophenol & Mercaptan; Phenoles and thiophenoles; Carbonyl Group Labeling Reagents for Fluorescence HPLC; Fluorescence Detection (HPLC Labeling Reagents); HPLC Labeling Reagents; Analytical Chemistry

2-Aminobenzenethiol Uses

2-Aminobenzenethiol (CAS NO.137-07-5) is used as an antinematodal agent, as well as an intermediate of belfosdil.

2-Aminobenzenethiol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	25mg/kg (25mg/kg)		National Technical Information Service. Vol. AD277-689,
mouse	LD50	intravenous	100mg/kg (100mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02532,
rat	LDLo	oral	500mg/kg (500mg/kg)	BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 90, 1969.

2-Aminobenzenethiol Consensus Reports

Reported in EPA TSCA Inventory.

2-Aminobenzenethiol Safety Profile

Hazard Codes: Corrosive C, Dangerous N
Risk Statements: 22-34-50/53-37-20/21/22
R22:Harmful if swallowed.
R34:Causes burns.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R37:Irritating to respiratory system
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37/39-45-60-61-25-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S25:Avoid contact with eyes.
S27:Take off immediately all contaminated clothing.
RIDADR: UN 1760 8/PG 3
WGK Germany: 3
RTECS: DC0600000
Hazard Note: Corrosive/Stench
HazardClass: 8
PackingGroup of 2-Aminobenzenethiol (CAS NO.137-07-5): III

2-Aminobenzenethiol Specification

2-Aminobenzenethiol (CAS NO.137-07-5), its Synonyms are 1-Amino-2-mercaptobenzene ; 2-Aminothiophenol ; 2-Mercaptaniline ; 2-Mercaptoaniline ; o-Aminobenzenethiol ; o-Aminothiophenol ; o-Mercaptoaniline ; Benzenethiol, 2-amino- ; Benzenethiol, o-amino- .

Product Name

2-Aminobenzenethiol

Synthetic route

2-Aminobenzenethiol Chemical Properties

2-Aminobenzenethiol Uses

2-Aminobenzenethiol Toxicity Data With Reference

2-Aminobenzenethiol Consensus Reports

2-Aminobenzenethiol Safety Profile

2-Aminobenzenethiol Specification

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