Conditions | Yield |
---|---|
With lipase of Pseudomonas sp; water In various solvent(s) at 25℃; for 5h; Hydrolysis; deacetylation; | 100% |
With sodium hydrogen telluride; acetic acid In ethanol for 0.5h; Heating; | 98% |
With 2,2-dibutyl-1,3,2-dioxastannane; cesium fluoride In N,N-dimethyl-formamide at 20℃; for 0.5h; | 98% |
ethyl (naphthalene-2-yl)carbonate
β-naphthol
Conditions | Yield |
---|---|
With sodium hydrogen telluride In ethanol for 0.5h; Quantum yield; Heating; buffer: deoxygen. acetic acid; | 100% |
With potassium tert-butylate; hydrogen; C16H18BrCoINO2 In dibutyl ether at 160℃; under 45004.5 Torr; for 20h; Sealed tube; Autoclave; | 75% |
2-naphthyl benzoate
2-amino-benzenethiol
A
2-Phenylbenzothiazole
B
β-naphthol
Conditions | Yield |
---|---|
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 100℃; for 0.75h; Hydrolysis; cyclization; debenzoylation; | A n/a B 100% |
2-naphthyl pivalate
2-amino-benzenethiol
A
2-(tert-butyl)benzo[d]thiazole
B
β-naphthol
Conditions | Yield |
---|---|
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 100℃; for 2h; Hydrolysis; cyclization; | A n/a B 100% |
Conditions | Yield |
---|---|
With potassium carbonate In 1-methyl-pyrrolidin-2-one for 0.5h; Heating; | 100% |
With potassium fluoride; thiophenol In 1-methyl-pyrrolidin-2-one for 0.5h; Heating; | 92% |
With HEPES buffer; human liver microsomal carboxylesterase 1 In dimethyl sulfoxide pH=7.4; Enzyme kinetics; Further Variations:; Reagents; |
6-bromo-naphthalen-2-ol
β-naphthol
Conditions | Yield |
---|---|
With triethylamine In isopropyl alcohol UV-irradiation; | 100% |
2-naphthyl tetrahydro-2H-pyran-2-yl ether
β-naphthol
Conditions | Yield |
---|---|
poly(4-vinylpyridinium) p-toluenesulfonate In tetrahydrofuran; ethanol at 75℃; for 20h; Hydrolysis; | 99% |
silica-supported prop-1-ylsulfonic acid In methanol | 99.4% |
With methanol; zirconium(IV) chloride at 20℃; for 6h; | 96% |
Conditions | Yield |
---|---|
With copper(I) oxide; tetra(n-butyl)ammonium hydroxide; 1,10-phenanthroline-4,7-diol In water at 110℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube; Green chemistry; | 99% |
With copper(l) iodide; potassium hydroxide In water at 120℃; for 12h; Inert atmosphere; | 96% |
With tris(6,6'-diamino-2,2'-bipyridine); 4,4-diphenyl-1,3,5,7,8-pentamethyl-2,6-diethyl-4-bora-3a,4a-diaza-s-indacene; Br2Ni*3H2O; water; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide; acetonitrile at 20℃; for 24h; Glovebox; Irradiation; Inert atmosphere; | 92% |
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; Ti(OiPr)[{(O-2,4-Me2C6H2)-6-CH2}3N]; magnesium In tetrahydrofuran at 40 - 50℃; for 12h; Inert atmosphere; regioselective reaction; | 99% |
With chloro-trimethyl-silane; sodium iodide In acetonitrile for 0.0333333h; | 98% |
With chloro-trimethyl-silane; sodium cyanoborohydride In acetonitrile at 20℃; for 0.25h; ether cleavage; | 98% |
β-naphthol
Conditions | Yield |
---|---|
With bismuth(lll) trifluoromethanesulfonate In methanol at 20℃; for 0.0333333h; | 99% |
montmorillonite K-10 for 0.0833333h; Solid phase reaction; desilylation; microwave irradiation; | 98% |
With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.15h; Green chemistry; | 98% |
β-naphthol
Conditions | Yield |
---|---|
With (triphenylphosphine)gold(I) chloride; silver trifluoromethanesulfonate In ethanol; benzene at 20℃; for 0.5h; | 99% |
naphthalene-2-boronic acid
β-naphthol
Conditions | Yield |
---|---|
With 1,3-dimethyl-5-ethyl-4a-hydroperoxyalloxazine; oxygen; hydrazine hydrate In methanol; 2,2,2-trifluoroethanol at 20℃; under 760.051 Torr; for 1h; | 99% |
With oxygen; triethylamine In acetonitrile at 20℃; under 760.051 Torr; for 4h; Kinetics; Catalytic behavior; Reagent/catalyst; Irradiation; | 99% |
With dihydrogen peroxide at 30℃; for 5h; Green chemistry; | 98% |
naphth-2-yloxymethylacetylene
β-naphthol
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; Ti(OiPr)[{(O-2,4-Me2C6H2)-6-CH2}3N]; magnesium In tetrahydrofuran at 40 - 50℃; for 12h; Inert atmosphere; regioselective reaction; | 99% |
With palladium on activated charcoal; ethanolamine In water at 80℃; Inert atmosphere; | 73% |
Conditions | Yield |
---|---|
With copper(I) oxide; 2-(N,N-dimethylamino)ethanol; water; potassium hydroxide In dimethyl sulfoxide at 100℃; for 24h; Reagent/catalyst; Temperature; Inert atmosphere; | 99% |
With glycolic Acid; copper hydroxide; sodium hydroxide In water; dimethyl sulfoxide at 120℃; for 6h; Inert atmosphere; Schlenk technique; | 94% |
With basolite C300; potassium hydroxide In water; dimethyl sulfoxide at 125℃; for 12h; | 90% |
Conditions | Yield |
---|---|
With 0.5%Pd/TiO2; isopropyl alcohol In water at 24.84℃; for 2h; Inert atmosphere; Sealed tube; Irradiation; | A 99% B 97% |
Conditions | Yield |
---|---|
With 1-Methylpyrrolidine; lithium aluminium tetrahydride; zirconocene dichloride In 2-methyltetrahydrofuran at 70℃; for 4h; Inert atmosphere; Schlenk technique; | 99% |
With acetic acid In water for 0.166667h; Reflux; | 95% |
Conditions | Yield |
---|---|
With L-Selectride In tetrahydrofuran at 67℃; for 48h; | 98% |
With dimethylboron bromide In 1,2-dichloro-ethane at 70℃; for 36h; | 96% |
With boron trichloride; tetra-(n-butyl)ammonium iodide In dichloromethane at -78 - 0℃; for 1h; dealkylation; | 96% |
2-(dimethyl-1,1’-dimethylethylsilyloxy)naphthalene
β-naphthol
Conditions | Yield |
---|---|
With carbonochloridic acid 1-chloro-ethyl ester In methanol at 20℃; for 20h; | 98% |
With potassium fluoride; Tetraethylene glycol at 20℃; for 0.5h; | 98% |
With SO3H silica gel In n-heptane at 50℃; for 0.5h; | 98% |
4-(2-naphthoxy)-butanoic acid
β-naphthol
Conditions | Yield |
---|---|
With PPA at 100℃; | 98% |
2-(tert-butoxycarbonyloxy)naphthalene
β-naphthol
Conditions | Yield |
---|---|
With 3-butyl-1-methylimidazolium acetate In water for 3h; Reflux; | 98% |
With methanol; carbon tetrabromide; triphenylphosphine for 2h; Reflux; | 92% |
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; 1,3-bis(adamantan-2-yl)imidazolin-2-yliden chloride; 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane; sodium t-butanolate In toluene at 130℃; for 20h; Sealed tube; Inert atmosphere; |
2-(tri(1-methylethyl)-silyloxy)naphthalene
β-naphthol
Conditions | Yield |
---|---|
With potassium fluoride In Tetraethylene glycol at 20℃; for 0.25h; Inert atmosphere; | 98% |
With potassium fluoride; Tetraethylene glycol at 20℃; for 0.25h; | 98% |
(3-hydroxynaphthalen-2-yl) boronic acid
β-naphthol
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 120℃; for 18h; | 98% |
In dimethyl sulfoxide at 120℃; | 98% |
Conditions | Yield |
---|---|
With Hβ-zeolite; sodium sulfite In methanol for 48h; Heating; | 97% |
With pyridine for 5.5h; Heating; | 93% |
With pyridine; palladium diacetate In N,N-dimethyl-formamide at 120℃; under 760 Torr; for 24h; | 82% |
2-naphthyl diethylcarbamate
β-naphthol
Conditions | Yield |
---|---|
With zirconocene dichloride In tetrahydrofuran at 20℃; Inert atmosphere; | 97% |
With zirconocene dichloride; lithium tri-t-butoxyaluminum hydride In tetrahydrofuran at 0 - 20℃; Product distribution / selectivity; | 95% |
β-naphthol
Conditions | Yield |
---|---|
With Oxone; water In acetone at 20℃; for 0.0333333h; | 97% |
With caesium carbonate; 1-acetyl-2-phenylhydrazine at 100℃; for 15h; | 90% |
Conditions | Yield |
---|---|
With ammonium bicarbonate In water at 20℃; for 2h; Schlenk technique; | 97% |
C26H26OSi
β-naphthol
Conditions | Yield |
---|---|
With potassium fluoride; Tetraethylene glycol at 20℃; for 0.5h; | 96% |
Conditions | Yield |
---|---|
With triethylammonium formate; palladium on activated charcoal for 0.166667h; Ambient temperature; | 95% |
With biphenyl; lithium In tetrahydrofuran; methanol at -78℃; for 40h; | 71% |
With hydrogen; palladium diacetate; pyrographite In tetrahydrofuran; methanol at 25℃; under 760.051 Torr; for 12h; | 66% |
Conditions | Yield |
---|---|
H6P2W18O62; silica gel In tetrahydrofuran; methanol at 65℃; for 1h; | 95% |
With trimethylsilyl bromide; 4 A molecular sieve In dichloromethane at -30℃; for 7h; | 80% |
With bismuth(III) chloride In water; acetonitrile at 50℃; for 3h; | 80% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; | 100% |
Conditions | Yield |
---|---|
zeolite HSZ-360 In neat (no solvent) at 60℃; for 1.5h; | 100% |
With magnesium(II) perchlorate at 20℃; for 0.33h; | 100% |
With SBA-15-Ph-Pr-SO3H at 20℃; for 1.16667h; | 100% |
Conditions | Yield |
---|---|
In chlorobenzene at 20℃; for 1h; | 100% |
Conditions | Yield |
---|---|
Stage #1: acetic acid With trifluoroacetic anhydride; indium(III) chloride at 20℃; Stage #2: β-naphthol at 20℃; for 0.166667h; | 100% |
With bismuth(III) chloride for 1.66667h; Heating; | 98% |
With phosphoric acid; trifluoroacetic anhydride at 20℃; for 0.0833333h; | 96% |
Conditions | Yield |
---|---|
With magnesium bis(trifluoromethane solfonyl)imide at 20℃; for 1h; | 100% |
With magnesium(II) perchlorate at 20℃; for 1h; | 97% |
With Cl(1-)*C5H14NO(1+)*3ZnCl2 In neat (no solvent) at 20℃; for 1.66667h; Green chemistry; | 92% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; | 100% |
Conditions | Yield |
---|---|
With sodium hydroxide In tetrahydrofuran; water at 0 - 20℃; for 2h; Green chemistry; | 100% |
With dmap; triethylamine In dichloromethane for 2.25h; Inert atmosphere; | 99% |
With 1,4-diaza-bicyclo[2.2.2]octane In dichloromethane at 0 - 20℃; Inert atmosphere; | 96% |
Conditions | Yield |
---|---|
With TiO(acac)2 In xylene for 36h; Heating; | 100% |
Stage #1: benzoic acid With trifluoroacetic anhydride; indium(III) chloride at 20℃; Stage #2: β-naphthol at 20℃; for 0.166667h; | 98% |
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane for 1h; Ambient temperature; | 91% |
Conditions | Yield |
---|---|
With ammonium chloride In ethanol at 200℃; for 20h; | 100% |
With water at 200 - 220℃; unter Druck; | |
With sodium hydrogensulfite In water Bucherer reaction; Autoclave; |
β-naphthol
1-deuterio-naphthalen-2-ol
Conditions | Yield |
---|---|
With bismuth(lll) trifluoromethanesulfonate; water-d2 In 1,2-dichloro-ethane at 80℃; for 24h; Inert atmosphere; | 100% |
With water-d2 Behandeln des Reaktionsprodukts mit wss. NaOH; | |
With water-d2; toluene-4-sulfonic acid at 60℃; for 24h; Inert atmosphere; |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; potassium iodide In methanol at 20℃; regioselective reaction; | 100% |
Stage #1: β-naphthol With ammonium iodide In methanol for 0.0333333h; Stage #2: In methanol | 98% |
With tert-butylhypochlorite; sodium iodide In water; acetonitrile at 0℃; for 0.166667h; | 95% |
Conditions | Yield |
---|---|
With C24H13Cu2F9N4O7; oxygen In isopropyl alcohol at 90℃; under 760.051 Torr; for 24h; | 100% |
With manganese (IV) dioxide In acetonitrile at 25℃; under 760.051 Torr; | 99.3% |
With 2,6-dimethylpyridine; sodium perchlorate In acetonitrile electrolysis; | 98.6% |
Conditions | Yield |
---|---|
With potassium hydrogensulfate; water; sodium nitrite Diazotization; coupling; microwave irradiation; | 100% |
Stage #1: 4-methoxy-aniline With ferric hydrogen sulphate; silica gel; sodium nitrite In water Green chemistry; Stage #2: β-naphthol In water at 20℃; for 0.05h; Green chemistry; regioselective reaction; | 97% |
Stage #1: 4-methoxy-aniline With water; sodium nitrite In neat (no solvent) at 20℃; Stage #2: β-naphthol In neat (no solvent) at 20℃; for 0.25h; | 94% |
Conditions | Yield |
---|---|
With potassium hydrogensulfate; water; sodium nitrite for 0.0333333h; Diazotization; coupling; microwave irradiation; | 100% |
With hydrogenchloride; sodium nitrite In water at 20℃; for 1h; Time; | 99% |
With hydrogenchloride; sodium nitrite In water at 20℃; for 0.0833333h; Reagent/catalyst; Temperature; Green chemistry; | 99% |
3,4-dihydro-2H-pyran
β-naphthol
2-naphthyl tetrahydro-2H-pyran-2-yl ether
Conditions | Yield |
---|---|
With pyridinium p-toluenesulfonate In dichloromethane for 1h; Ambient temperature; | 100% |
With H6P2W18O62 In toluene at 20℃; for 2h; | 100% |
silica-supported prop-1-ylsulfonic acid In acetonitrile for 0.166667h; | 99.6% |
Conditions | Yield |
---|---|
for 24h; Heating; | 100% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h; Inert atmosphere; | 100% |
With potassium carbonate In tetrahydrofuran at 20℃; for 8h; | 94% |
With sodium hydride In N,N-dimethyl-formamide for 3h; Ambient temperature; | 70% |
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere; | 100% |
With pyridine In dichloromethane at 25℃; for 16h; Inert atmosphere; | 99% |
With pyridine In dichloromethane at 0 - 20℃; | 99% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In methanol; hexane; acetonitrile for 15h; Ambient temperature; | 100% |
N-<α-(benzotriazol-1-yl)benzyl>-3-pyridinecarboxamide
β-naphthol
N-[(2-Hydroxy-naphthalen-1-yl)-phenyl-methyl]-nicotinamide
Conditions | Yield |
---|---|
With aluminium trichloride In dichloromethane for 4h; Heating; | 100% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane for 0.5h; Ambient temperature; | 100% |
β-naphthol
1-fluoronaphthalen-2-ol
Conditions | Yield |
---|---|
With N-4-fluorobis(phenylsulfonyl)amine In acetonitrile Ambient temperature; | 100% |
Stage #1: β-naphthol With N,N'-difluoro-2,2'-bipyridinium bis(triflate) In carbon dioxide at 20℃; for 12h; Stage #2: With hydrogen; palladium on activated charcoal In ethanol at 20℃; for 8h; | 99% |
With N-fluorobis(benzenesulfon)imide; zirconium(IV) chloride In dichloromethane at 0 - 20℃; for 18h; | 51% |
Conditions | Yield |
---|---|
With caesium carbonate; copper(I) bromide; 1,1'-azobis(1-cyanocyclohexanenitrile) In N,N-dimethyl-formamide at 100℃; for 0.5h; Microwave irradiation; Green chemistry; | 100% |
With copper(l) iodide; 2-carbomethoxy-3-hydroxyquinoxaline-di-N-oxide; caesium carbonate In N,N-dimethyl-formamide at 100℃; for 12h; Schlenk technique; Inert atmosphere; | 93% |
With potassium carbonate In dimethyl sulfoxide at 80℃; for 12h; Catalytic behavior; Ullmann Condensation; Sealed tube; Schlenk technique; | 91% |
Conditions | Yield |
---|---|
With 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene on polystyrene.HL In acetonitrile at 80℃; Esterification; | 100% |
With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature; | 92% |
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h; Substitution; | 92% |
β-naphthol
(E)-o-carboxycinnamic acid
Conditions | Yield |
---|---|
With bis(o-nitrophenyl) diselenide; dihydrogen peroxide In tert-butyl alcohol at 55℃; for 6h; | 100% |
With poly(bis-1,2-diphenylene) diselenide; dihydrogen peroxide In tetrahydrofuran; water for 20h; Heating; | 98% |
With oxone In water; acetonitrile at 20℃; for 10h; | 80% |
β-naphthol
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 16h; | 100% |
With triethylamine In acetonitrile Substitution; Heating; | 93% |
With triethylamine In acetonitrile for 18h; Heating; | 93% |
β-naphthol
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 16h; | 100% |
With triethylamine In acetonitrile Substitution; Heating; | 99% |
2-Naphthol (CAS NO.135-19-3) is an intermediate of naphthalene acid which is a plant growth regulator.
2-Naphthol is used as a feed preservative and analytical reagent.
2-Naphthol is an important organic raw material and dyes intermediate, for the manufacture of Tobias acid, butyric acid, β-naphthol-3-carboxylic acid, and used to manufacture antioxidant, Antioxidant DNP, and other antioxidant, organic pigments and fungicides.
Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
The 2-Naphthol, with the CAS registry number 135-19-3,is also known as 2-Hydroxynaphthalene; 2-Naphthalenol; beta-Hydroxynaphthalene. It belongs to the product categories of Organic Building Blocks;Oxygen Compounds;Particles and Stains.Its EINECS number is 205-182-7. This chemical's molecular formula is C10H8O and molecular weight is 144.17. What's more,Its systematic name is 2-Naphthalenol.It is a white or off-white powder with a slight which is stable, Combustible,dust may form explosive mixture with air,incompatible with strong oxidizing agents,phenol.It is an important organic raw material and dyes intermediate, for the manufacture of Tobias acid, butyric acid, β-naphthol-3-carboxylic acid, and used to manufacture antioxidant, Antioxidant DNP, and other antioxidant, organic pigments and fungicides.
Physical properties about 2-Naphthol are:
(1)ACD/LogP: 2.724; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.72; (4)ACD/LogD (pH 7.4): 2.72; (5)ACD/BCF (pH 5.5): 69.26; (6)ACD/BCF (pH 7.4): 68.80; (7)ACD/KOC (pH 5.5): 722.79; (8)ACD/KOC (pH 7.4): 718.00; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.678; (13)Molar Refractivity: 45.977 cm3; (14)Molar Volume: 121.979 cm3; (15)Surface Tension: 51.0940017700195 dyne/cm; (16)Density: 1.182 g/cm3; (17)Flash Point: 144.002 °C; (18)Enthalpy of Vaporization: 54.56 kJ/mol; (19)Boiling Point: 285.499 °C at 760 mmHg; (20)Vapour Pressure: 0.0020000000949949 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES:c1ccc2cc(ccc2c1)O;
(2)Std. InChI:InChI=1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H;
(3)Std. InChIKey:JWAZRIHNYRIHIV-UHFFFAOYSA-N.
The toxicity data of 2-Naphthol are as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | oral | 100mg/kg (100mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
guinea pig | LD50 | oral | 1335mg/kg (1335mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 30(9), Pg. 22, 1965. | |
guinea pig | LDLo | subcutaneous | 2670mg/kg (2670mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 186, Pg. 195, 1937. |
mouse | LD50 | intraperitoneal | 97500mg/kg (97500mg/kg) | European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 381, 1978. | |
mouse | LDLo | oral | 100mg/kg (100mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
mouse | LDLo | subcutaneous | 100mg/kg (100mg/kg) | Zeitschrift fuer Hygiene und Infektionskrankheiten. Vol. 64, Pg. 113, 1909. | |
rabbit | LD50 | skin | > 10gm/kg (10000mg/kg) | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 26-4/1973, | |
rabbit | LDLo | oral | 3800mg/kg (3800mg/kg) | Yakkyoku. Pharmacy. Vol. 31, Pg. 1499, 1980. | |
rabbit | LDLo | subcutaneous | 3gm/kg (3000mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
rabbit | LDLo | unreported | 3800mg/kg (3800mg/kg) | Yakkyoku. Pharmacy. Vol. 32, Pg. 605, 1981. | |
rat | LC50 | inhalation | > 770mg/m3/1H (770mg/m3) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 26-4/1973, |
rat | LD50 | oral | 1960mg/kg (1960mg/kg) | Gigiena Truda i Professional'naya Patologiya v Estonskoi SSR. Labor Hygiene and Occupational Pathology in the Estonian SSR. Vol. 8, Pg. 145, 1972. | |
rat | LDLo | subcutaneous | 2940mg/kg (2940mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 186, Pg. 195, 1937. |
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