3-Butoxypropanamine supplier | CasNO.16499-88-0

Name
3-Butoxypropanamine
EINECS 240-566-8
CAS No. 16499-88-0
Article Data12
CAS DataBase
Density 0.851 g/cm³
Solubility miscible with water
Melting Point -65 °C
Formula C₇H₁₇NO
Boiling Point 169.7 °C at 760 mmHg
Molecular Weight 131.218
Flash Point 63.3 °C
Transport Information UN 2735 8/PG 2
Appearance clear colorless liquid
Safety 26-27-36/37/39-45
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms Propylamine,3-butoxy- (6CI,7CI,8CI);3-(Butyloxy)propylamine;3-(n-Butoxy)propylamine;3-Aminopropyl butyl ether;3-Butoxy-1-propanamine;
PSA 35.25000
LogP 1.85220

Synthetic route

: 6959-71-3
3-butoxypropanenitrile

: 16499-88-0
3-butoxypropylamine

Conditions

Conditions	Yield
With methanol; ammonia; nickel at 100℃; under 66195.7 - 88260.9 Torr; Hydrogenation;
With lithium aluminium tetrahydride; diethyl ether
With hydrogen; nickel In ethanol
With hydrogen; Ni(Raney)

: 107-13-1
acrylonitrile

: 71-36-3
butan-1-ol

: 16499-88-0
3-butoxypropylamine

Conditions

Conditions	Yield
With sodium; toluene

: 542-76-7
3-Chloropropionitrile

: 71-36-3
butan-1-ol

: 16499-88-0
3-butoxypropylamine

Conditions

Conditions	Yield
With sodium; toluene

: 1656-48-0
2-cyanoethyl ether

: 71-36-3
butan-1-ol

: 16499-88-0
3-butoxypropylamine

Conditions

Conditions	Yield
With sodium

: 6959-71-3
3-butoxypropanenitrile

: 71-36-3
butan-1-ol

: 16499-88-0
3-butoxypropylamine

Conditions

Conditions	Yield
With sodium

: 107-13-1
acrylonitrile

: 71-36-3
butan-1-ol

sodium: sodium

A: 107-10-8
propylamine

B: 16499-88-0
3-butoxypropylamine

...Expand

: 110-67-8
3-Methoxypropionitrile

: 71-36-3
butan-1-ol

sodium: sodium

: 16499-88-0
3-butoxypropylamine

...Expand

: 1656-48-0
2-cyanoethyl ether

: 71-36-3
butan-1-ol

sodium: sodium

: 16499-88-0
3-butoxypropylamine

...Expand

: 109-99-9
tetrahydrofuran

: 6959-71-3
3-butoxypropanenitrile

lithium alanate: lithium alanate

A: 16499-88-0
3-butoxypropylamine

B: 71-36-3
butan-1-ol

C hydrogen: hydrogen

Conditions

Conditions	Yield
at 30 - 35℃; Ausbeute bei unterschiedlichem Mengenverhaeltnis der Reaktionspartner;

...Expand

: 60-29-7
diethyl ether

: 6959-71-3
3-butoxypropanenitrile

lithium alanate: lithium alanate

A: 16499-88-0
3-butoxypropylamine

B: 71-36-3
butan-1-ol

C hydrogen: hydrogen

Conditions

Conditions	Yield
at 35℃; Ausbeute bei unterschiedlichem Mengenverhaeltnis der Reaktionspartner;

...Expand

: 16499-88-0
3-butoxypropylamine

: 273730-47-5
1-[(tert-butoxycarbonyl)methoxy]-2,6-bis{2'-[(tert-butoxycarbonyl)methoxy]-3'-formyl-5'-methylphenyl}-4-methylbenzene

: 243129-88-6
1-[(tert-butoxycarbonyl)methoxy]-2,6-bis{2'-[(tert-butoxycarbonyl)methoxy]-3'-(n-butoxypropylaminomethyl)-5'-methylphenyl}-4-methylbenzene

Conditions

Conditions	Yield
Stage #1: 3-butoxypropylamine; 1-[(tert-butoxycarbonyl)methoxy]-2,6-bis{2'-[(tert-butoxycarbonyl)methoxy]-3'-formyl-5'-methylphenyl}-4-methylbenzene In ethanol at 20℃; for 0.5h; Condensation; Stage #2: With hydrogen; palladium on activated charcoal In ethanol at 20℃; Catalytic hydrogenation; Further stages.;	100%

: 16499-88-0
3-butoxypropylamine

: S-acrylic acid-N-butoxypropyl dithiocarbamate

A: N,N'-dibutoxypropyl thiourea

B: 107-96-0
3-mercaptopropionic acid

Conditions

Conditions	Yield
With sodium hydroxide In water at 70℃; for 2h;	A 98.5% B 95.7%

...Expand

: 16499-88-0
3-butoxypropylamine

: 1603109-24-5
C15H21NO6

: C22H36N2O6

Conditions

Conditions	Yield
In toluene Reflux;	95%

: 16499-88-0
3-butoxypropylamine

: S-acrylic acid-N-isopropoxypropyl dithiocarbamate

A: N-isopropoxypropyl-N'-butoxypropyl thiourea

B: 107-96-0
3-mercaptopropionic acid

Conditions

Conditions	Yield
With sodium hydroxide In water at 70℃; for 2.5h;	A 94.9% B 93.6%

...Expand

: 620-08-6
4-methoxypyridine

: 16499-88-0
3-butoxypropylamine

: N-(3-butoxypropyl)pyridin-4-amine

Conditions

Conditions	Yield
Stage #1: 3-butoxypropylamine With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: 4-methoxypyridine In tetrahydrofuran; hexane at 60℃; for 0.5h; Inert atmosphere; Schlenk technique;	94%

: 686-69-1
diethylchlorophosphine

: 16499-88-0
3-butoxypropylamine

: C15H35NP2O

Conditions

Conditions	Yield
With triethylamine In dichloromethane	87%
With triethylamine In dichloromethane at 20℃; for 20h;	87%

: 16499-88-0
3-butoxypropylamine

: 965-66-2
2α,3α-epoxy-5α-androstan-17β-ol

: 1031816-30-4
2β-(3-butoxypropylamino)-5α-androstane-3α,17β-diol

Conditions

Conditions	Yield
With gadolinium(III) trifluoromethanesulfonate In toluene at 150 - 190℃; for 2h;	82%

: 1072-72-6
Tetrahydrothiopyran-4-one

: 50-00-0
formaldehyd

: 16499-88-0
3-butoxypropylamine

: 941579-43-7
7-(3-butoxypropyl)-3-thia-7-azabicyclo[3.3.1]nonan-9-one

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid In methanol for 8h; Mannich cyclization; Heating;	78%

...Expand

: 16499-88-0
3-butoxypropylamine

: 169499-08-5
N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-phenylalanine

: 174699-37-7
N-[N-[(2S,3S)-3-trans-ethoxycarbonyloxirane-2-carbonyl]-L-phenylalanyl]-1-amino-3-butoxypropane

Conditions

Conditions	Yield
	75%

: 16499-88-0
3-butoxypropylamine

: 3,6-difluoro-9-(3-(3-fluoro-9H-carbazol-9-yl)-2-(oxiran-2-ylmethoxy)propyl)-9H-carbazole

: 1-((3-butoxypropyl)amino)-3-((1-(3,6-difluoro-9H-carbazol-9-yl)-3-(3-fluoro-9H-carbazol-9-yl)propan-2-yl)oxy)propan-2-ol

Conditions

Conditions	Yield
In isopropyl alcohol at 60℃; Sealed tube;	73.02%

: 16499-88-0
3-butoxypropylamine

: 107-13-1
acrylonitrile

: 3-butoxypropyl-2-cyanoethylamine

Conditions

Conditions	Yield
In methanol at 25℃; for 2h;	69%

: 16499-88-0
3-butoxypropylamine

: 81-64-1
1,4-dihydroxy-9,10-anthracenedione

: 1-(n-butoxypropylamino)-4-hydroxy-9,10-anthracenedione

Conditions

Conditions	Yield
With morpholine; sodium tetrahydroborate In 1,4-dioxane; diethylene glycol dimethyl ether for 6h; Reflux;	61%

: 16499-88-0
3-butoxypropylamine

: 3-fluoro-9-(oxiran-2-ylmethyl)-9H-carbazole

: 1-((3-butoxypropyl)amine)-3-(3-fluoro-9H-carbazol-9-yl)-2-propanol

Conditions

Conditions	Yield
In ethanol at 60℃; Sealed tube;	59.09%

: 50-00-0
formaldehyd

: 16499-88-0
3-butoxypropylamine

: 81267-65-4
idronoxil

: 4-(3-(3-butoxypropyl)-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

Conditions

Conditions	Yield
Stage #1: formaldehyd; 3-butoxypropylamine In ethanol; water at 45℃; for 1h; Mannich Aminomethylation; Stage #2: idronoxil In ethanol; water at 20℃; for 48h; Mannich Aminomethylation;	54%

...Expand

: 827025-82-1
(E)-3-{(2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[(2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-((E)-2-methoxycarbonyl-vinyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-2-yl}-acrylic acid methyl ester

: 16499-88-0
3-butoxypropylamine

: 827025-92-3
(E)-N-(3-Butoxy-propyl)-3-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-{(2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-[(E)-2-(3-butoxy-propylcarbamoyl)-vinyl]-tetrahydro-pyran-2-yloxy}-tetrahydro-pyran-2-yl)-acrylamide

Conditions

Conditions	Yield
With trimethylaluminum In dichloromethane; toluene at 20℃;	39%

: 16499-88-0
3-butoxypropylamine

: 403-54-3
m-Fluorobenzonitrile

: 3-(3-butoxy-propylamino)-benzonitrile

Conditions

Conditions	Yield
In dimethyl sulfoxide at 100℃; for 60h; Substitution;	38%

: 16499-88-0
3-butoxypropylamine

: 3,6-difluoro-9-(oxiran-2-ylmethyl)-9H-carbazole

: 1-((3-butoxypropyl)amino)-3-(3,6-difluoro-9H-carbazol-9-yl)-2-propanol

Conditions

Conditions	Yield
In ethanol at 60℃; Sealed tube;	34.44%

: 16499-88-0
3-butoxypropylamine

: 95-96-5
D,L-lactide

: 950500-93-3
N-(3-butoxypropyl) lactamide

Conditions

Conditions	Yield
at 20℃; under 760.051 Torr; for 96h;	25%

: 16499-88-0
3-butoxypropylamine

: 2210-24-4
N-acryloylaniline

: N3-(3-anilino-3-oxopropyl)-N3-(3-butoxypropyl)-N1-phenyl-β-alaninamide

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile for 16h; Inert atmosphere; Reflux;	25%

: 16499-88-0
3-butoxypropylamine

: 81-30-1
1,4,5,8-naphthalenetetracarboxylic dianhydride

: 2,7-bis-(3-butoxy-propyl)-benzo[lmn][3,8]phenanthroline-1,3,6,8-tetraone

Conditions

Conditions	Yield
With quinoline; zinc diacetate at 200℃; imidation;	10%

: 110-52-1
1,4-dibromo-butane

: 16499-88-0
3-butoxypropylamine

: 1-(3-butoxy-propyl)-pyrrolidine

Conditions

Conditions	Yield
With potassium carbonate; benzene

: 111-24-0
1,5-dibromo-pentane

: 16499-88-0
3-butoxypropylamine

: 1-(3-butoxy-propyl)-piperidine

Conditions

Conditions	Yield
With potassium carbonate; benzene

: 16499-88-0
3-butoxypropylamine

: 91897-80-2
1-(1'-cyclohexenyl)-2-buten-1-one

: 91897-81-3
(Z)-1-(cyclohexen-1-yl)-2-buten-1-one

: 101572-81-0
1-(3-butoxy-propyl)-2-methyl-octahydro-quinolin-4-one

Conditions

Conditions	Yield
With methanol; water

...Expand

: 16499-88-0
3-butoxypropylamine

: 4083-64-1
Tosyl isocyanate

: 101261-39-6
N-(3-butoxy-propyl)-N'-(toluene-4-sulfonyl)-urea

: 16499-88-0
3-butoxypropylamine

: 129-64-6
3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride

: 101256-17-1
2-(3-butoxy-propyl)-(3ac,7ac)-3a,4,7,7a-tetrahydro-4r,7c-methano-isoindole-1,3-dione

Conditions

Conditions	Yield
With toluene at 160℃;

3-Butoxypropanamine Chemical Properties

IUPAC Name: 3-butoxypropan-1-amine
EINECS: 240-566-8
CAS NO: 16499-88-0
Molecular Formula of 3-Butoxypropanamine (CAS NO.16499-88-0): C₇H₁₇NO
Molecular Weight: 131.216
Molecular Structure:

Melting Point: -65 °C
Polar Surface Area: 12.47 Å²
Index of Refraction: 1.429
Molar Refractivity: 39.75 cm³
Molar Volume: 154.1 cm³
Surface Tension: 29.5 dyne/cm
Water solubility: miscible
Density of 3-Butoxypropanamine (CAS NO.16499-88-0): 0.851 g/cm³
Flash Point: 63.3 °C
Enthalpy of Vaporization: 40.61 kJ/mol
Boiling Point: 169.7 °C at 760 mmHg
Vapour Pressure: 1.52 mmHg at 25°C
Product Categories: Amino Alcohols; Organic Building Blocks; Oxygen Compounds
InChI
InChI=1/C7H17NO/c1-2-3-6-9-7-4-5-8/h2-8H2,1H3
Smiles
O(CCCC)CCCN

3-Butoxypropanamine Safety Profile

Hazard Codes: Corrosive C
Risk Statements: 34
R34: Causes burns.
Safety Statements: 26-27-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27: Take off immediately all contaminated clothing.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2735 8/PG 2
WGK Germany: 3
HazardClass: 8
PackingGroup: III

3-Butoxypropanamine Specification

3-Butoxypropanamine , with CAS number of 16499-88-0, can be called 1-propanamine, 3-butoxy- ; 3-Butoxy-1-propylamine ; 3-Butoxypropan-1-amine ; 3-N-Butoxypropylamine ; Propylamine,3-butoxy- (6CI,7CI,8CI). It is a clear colorless liquid.

Product Name

3-Butoxypropanamine

Synthetic route

3-Butoxypropanamine Chemical Properties

3-Butoxypropanamine Safety Profile

3-Butoxypropanamine Specification

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