3-Methylbenzyl chloride supplier

Name
3-Methylbenzyl chloride
EINECS 210-628-9
CAS No. 620-19-9
Article Data47
CAS DataBase
Density 1.054 g/cm³
Solubility insoluble in water
Melting Point -41.95°C (estimate)
Formula C₈H₉Cl
Boiling Point 197.9 °C at 760 mmHg
Molecular Weight 140.612
Flash Point 75.6 °C
Transport Information UN 3265 8/PG 2
Appearance clear colorless to slightly yellow liquid
Safety 23-26-27-36/37/39-45-37/39
Risk Codes 34-36/37-36/37/38
Molecular Structure
Hazard Symbols Xi, C
Synonyms m-Xylene, a-chloro- (7CI,8CI);1-Chloromethyl-3-methylbenzene;1-Methyl-3-chloromethylbenzene;3-(Chloromethyl)toluene;3-Methylphenylmethylchloride;NSC 76592;m-(Chloromethyl)toluene;m-Methylbenzyl chloride;m-Xylylchloride;m-Xylyl-a-chloride;a-Chloro-m-xylene;Benzene,1-(chloromethyl)-3-methyl-;
PSA 0.00000
LogP 2.73380

Synthetic route

: 620-23-5
m-tolyl aldehyde

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With chloro-trimethyl-silane; trimethylsilan In acetic acid methyl ester at 0℃; for 4h;	80%

: 36583-13-8
3-methylbenzyl Co(III)(dmgH)2py

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With chlorine In chloroform a solution of two equivalents of halogen added dropwise to a solution of organocobaloxime at room temperature under nitrogen in the dark; NMR, UV;	75%
With chlorine In acetic acid a solution of two equivalents of halogen added dropwise to a solution of organocobaloxime at room temperature under nitrogen in the dark; NMR, UV;	75%

: 108-38-3
m-xylene

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With N-chloro-succinimide In 1,2-dichloro-ethane at 80℃; regiospecific reaction;	70%
With N-hydroxyphthalimide; carbon tetrabromide; trichloroisocyanuric acid; copper(II) acetate monohydrate In dichloromethane at 25℃; for 42h;	33%
With N-chloro-succinimide; N-hydroxyphthalimide; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile at 80℃; for 16h; Time; Sealed tube; Inert atmosphere;	26%

: 128-09-6
N-chloro-succinimide

: 108-38-3
m-xylene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 626-16-4
3-(chloromethyl)benzyl chloride

Conditions

Conditions	Yield
Irradiation.UV-Licht;

...Expand

: 587-03-1
3-methylbenzyl alcohol

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With hydrogenchloride at 60 - 70℃;

: 56-23-5
tetrachloromethane

: 27876-29-5
acetic acid-(2,4,6,N-tetrachloro-anilide)

: 108-38-3
m-xylene

: 94-36-0
dibenzoyl peroxide

: 620-19-9
1-chloromethyl-3-methyl-benzene

...Expand

: 1711-06-4
3-Methylbenzoyl chloride

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With triethylsilane; zinc(II) chloride

: 60154-94-1
3-methyl-benzylium

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With tertiary butyl chloride In gaseous matrix at 600℃; chloride affinity;

: 24154-22-1
dichloro-phenyl-methylium

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With tertiary butyl chloride In gaseous matrix at 600℃; chloride affinity;

: 75366-05-1
3-methylbicyclo<4.1.0>hepta-1,3,5-triene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 104-82-5
4-Methylbenzyl chloride

Conditions

Conditions	Yield
With hydrogenchloride In tetrachloromethane for 1h; Yield given. Yields of byproduct given;

: 75366-04-0
2-methyl-1H-cyclopropabenzene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 552-45-4
1-chloromethyl-2-methylbenzene

Conditions

Conditions	Yield
With hydrogenchloride In tetrachloromethane for 1h; Product distribution; Mechanism; reaction regioselectivity; a series of reagents;

: 108-38-3
m-xylene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 626-16-4
3-(chloromethyl)benzyl chloride

C: 30220-25-8
m-chloromethylbenzylidene chloride

D: 2719-42-8
α,α-dichloro-m-xylene

E: 30430-40-1
α,α,α',α'-Tetrachloro-m-xylene

Conditions

Conditions	Yield
With 2,2'-azobis(isobutyronitrile); chlorine at 70℃; for 1.2h; Product distribution; various educt-reagent ratio, various time;

...Expand

: 38226-17-4
<(3-methylphenyl)methyl>trimethylsilane

: 1801-77-0
oxovanadium(V) ethoxydichloride

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 64988-09-6
α-ethoxy-m-xylene

Conditions

Conditions	Yield
In acetonitrile Product distribution; -30 deg C, 2 h; RT, 4 h;

...Expand

: 108-38-3
m-xylene

A: 95-66-9
2,4-dimethylchlorobenzene

B: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
With perchloric acid; trichloroisocyanuric acid In acetic acid at 35℃; Rate constant; Mechanism;
With perchloric acid; trichloroisocyanuric acid In acetic acid at 35℃;

: 626-16-4
3-(chloromethyl)benzyl chloride

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 4662-96-8
1,2-di-m-tolylethane

C: C16H17Cl

Conditions

Conditions	Yield
With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In tetrahydrofuran; N,N-dimethyl-formamide Ambient temperature; n-Bu4NBF4, Hg pool cathode, SCE reference electrode;	A 1 % Spectr. B 43 % Spectr. C 12 % Spectr.

...Expand

: 107-30-2
chloromethyl methyl ether

: 108-88-3
toluene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 552-45-4
1-chloromethyl-2-methylbenzene

C: 104-82-5
4-Methylbenzyl chloride

Conditions

Conditions	Yield
With tin(IV) chloride In dichloromethane at 25℃; Rate constant; Mechanism;	A 0.5 % Chromat. B 31 % Chromat. C 69 % Chromat.

...Expand

: 107-30-2
chloromethyl methyl ether

: 108-88-3
toluene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 552-45-4
1-chloromethyl-2-methylbenzene

C: 104-82-5
4-Methylbenzyl chloride

D: Methanol; compound with GENERIC INORGANIC NEUTRAL COMPONENT

Conditions

Conditions	Yield
With aluminium trichloride In nitromethane at 0℃; Product distribution; Mechanism;	A 0.37 % Chromat. B 31 % Chromat. C 68 % Chromat. D n/a

...Expand

: 38870-89-2
Methoxyacetyl chloride

: 108-88-3
toluene

A: 201230-82-2
carbon monoxide

B: 620-19-9
1-chloromethyl-3-methyl-benzene

C: 552-45-4
1-chloromethyl-2-methylbenzene

D: 104-82-5
4-Methylbenzyl chloride

Conditions

Conditions	Yield
With tin(IV) chloride In dichloromethane at 25℃; Rate constant;

...Expand

: 38870-89-2
Methoxyacetyl chloride

: 108-88-3
toluene

A: 201230-82-2
carbon monoxide

B: 620-19-9
1-chloromethyl-3-methyl-benzene

C: 552-45-4
1-chloromethyl-2-methylbenzene

D: 104-82-5
4-Methylbenzyl chloride

E: Methanol; compound with GENERIC INORGANIC NEUTRAL COMPONENT

Conditions

Conditions	Yield
With aluminium trichloride In nitromethane at 0℃; for 0.555h; Product distribution; Rate constant; Mechanism; effects of various periods of time (up to 1072.5 min) and conc. of AlCl3;	A n/a B 0.52 % Chromat. C 26.54 % Chromat. D 73.22 % Chromat. E n/a

...Expand

: 191402-56-9
4-(1-Chloro-2,2,2-trifluoro-ethyl)-1,2-dimethyl-benzene

: 60154-94-1
3-methyl-benzylium

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 128408-29-7
C10H10F3(1+)

Conditions

Conditions	Yield
at 69.85℃; Thermodynamic data; chloride-transfer;

...Expand

: 7782-50-5
chlorine

: 108-38-3
m-xylene

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
Dampfphase.Irradiation;
Irradiation;

: 56-23-5
tetrachloromethane

: 7791-25-5
sulfuryl dichloride

: 108-38-3
m-xylene

: 94-36-0
dibenzoyl peroxide

: 620-19-9
1-chloromethyl-3-methyl-benzene

...Expand

: 7647-01-0
hydrogenchloride

: 50-00-0
formaldehyd

: 7732-18-5
water

: 108-88-3
toluene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 552-45-4
1-chloromethyl-2-methylbenzene

C: 104-82-5
4-Methylbenzyl chloride

...Expand

: 99-04-7
m-Toluic acid

: 620-19-9
1-chloromethyl-3-methyl-benzene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aqueous-alcoholic sulfuric acid / bei der elektrolytischen Reduktion 2: hydrogen chloride / 60 - 70 °C View Scheme

: 108-38-3
m-xylene

A: 620-19-9
1-chloromethyl-3-methyl-benzene

B: 626-16-4
3-(chloromethyl)benzyl chloride

Conditions

Conditions	Yield
With 2,2'-azobis(isobutyronitrile); 1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril In tetrachloromethane at 81℃; for 2h; Inert atmosphere;	A 52 %Chromat. B 16 %Chromat.

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 603-35-0
triphenylphosphine

: 63368-37-6
(3-methylbenzyl)triphenylphosphonium chloride

Conditions

Conditions	Yield
In acetonitrile for 4.5h; Reflux;	100%
In benzene
Yield given;
In 5,5-dimethyl-1,3-cyclohexadiene at 20℃; Reflux;	28 g
In toluene at 20℃; Reflux;

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1178094-73-9
(Z)-6-methoxy-2-(pyridin-4-ylmethylene)benzofuran-3(2H)-one

: 1250364-34-1
(Z)-1-(3-methylbenzyl)-4-((6-methoxy-3-oxobenzofuran-2(3H)-ylidene)methyl)pyridinium chloride

Conditions

Conditions	Yield
In acetonitrile Reflux;	100%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1250364-18-1
(Z)-6-ethoxy-2-(pyridin-4-ylmethylene)benzofuran-3(2H)-one

: 1250364-49-8
(Z)-1-(3-methylbenzyl)-4-((6-ethoxy-3-oxobenzofuran-2(3H)-ylidene)methyl)pyridinium chloride

Conditions

Conditions	Yield
In acetonitrile Reflux;	100%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1250364-19-2
(Z)-6-propoxy-2-(pyridin-4-ylmethylene)benzofuran-3(2H)-one

: 1250364-60-3
(Z)-1-(3-methylbenzyl)-4-((6-propoxy-3-oxobenzofuran-2(3H)-ylidene)methyl)pyridinium chloride

Conditions

Conditions	Yield
In acetonitrile Reflux;	100%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 108-38-3
m-xylene

Conditions

Conditions	Yield
With palladium dichloride In methanol at 40℃; for 1h; Green chemistry; chemoselective reaction;	99%
With Perbenzoic acid; tri-n-butyl-tin hydride In benzene at 90℃; for 12h; Mechanism; in the presence of α-chlorotoluene (competitor), relative reactivity;

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 98-80-6
phenylboronic acid

: 620-47-3
1-methyl-3-(phenylmethyl)-benzene

Conditions

Conditions	Yield
With C58H82Cl4N6Pd2; potassium tert-butylate In water; isopropyl alcohol at 80℃; for 4h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere;	99%
With potassium phosphate; triphenylphosphine; palladium diacetate In toluene for 19h; Suzuki cross-coupling reaction;	96%
With potassium phosphate; C114H132Cl6N10Pd3 In water; isopropyl alcohol at 80℃; for 6h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;	96%
With potassium carbonate; N,N-dimethyl-formamide; palladium dichloride In water at 90℃; for 1h; Suzuki Coupling;	90%
With potassium carbonate; sodium chloride; palladium dichloride; cucurbituril In ethanol; water at 90℃; for 1h; Suzuki Coupling; Inert atmosphere;	76%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 31614-66-1
tributyl(p-tolyl)stannane

: 21895-16-9
1-methyl-3-(4-methylbenzyl)benzene

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; potassium fluoride; palladium diacetate In 1,4-dioxane at 80℃; for 3h; Stille cross-coupling;	99%

: 4394-85-8
4-morpholinecarboxaldehyde

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 90754-64-6
4-(3-methylbenzyl)morpholine

Conditions

Conditions	Yield
With NHC-Pd(II)-Im; sodium hydroxide In water at 50℃; for 3h; Inert atmosphere; Schlenk technique;	99%
With potassium hydroxide In water at 50℃; for 3h; Green chemistry;	80%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 106-45-6
para-thiocresol

: 1312161-87-7
1-methyl-3-((p-tolylsulfinyl)methyl)benzene

Conditions

Conditions	Yield
With iodine pentoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 90℃; for 6h;	99%
With iodine pentoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 100℃; for 6h;	98%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 620-23-5
m-tolyl aldehyde

Conditions

Conditions	Yield
With water; sodium hydroxide at 20℃; for 0.05h; Microwave irradiation;	98%
With 4-methylmorpholine N-oxide; 1-ethyl-3-methyl-1H-imidazol-3-ium chloride; potassium iodide at 100℃; for 0.0333333h; Microwave irradiation; Ionic liquid;	90%
With 4-methylmorpholine N-oxide In tetrahydrofuran at 20℃; for 12h; Reflux;	80%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 615-43-0
2-iodophenylamine

: 1211-32-1
2-(m-tolyl)benzo[d]thiazole

Conditions

Conditions	Yield
With copper(II) acetate monohydrate; sodium carbonate; sulfur In dimethyl sulfoxide at 130℃; for 24h; Schlenk technique; Inert atmosphere;	98%

: 100-02-7
4-nitro-phenol

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1-methyl-3-((4-nitrophenoxy)methyl)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 24h;	98%

: 1632-83-3
1-Methylbenzimidazole

: 620-19-9
1-chloromethyl-3-methyl-benzene

: C16H17N2(1+)*Cl(1-)

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 95℃; for 4h; Inert atmosphere; Schlenk technique;	97%

: 616-47-7
1-methyl-1H-imidazole

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 958445-59-5
1-methyl-3-(3’-methylbenzyl)imidazolium chloride

Conditions

Conditions	Yield
In acetonitrile for 48h; Inert atmosphere; Reflux;	96%
In tetrahydrofuran at 69.84℃; for 48h;	94%
In acetonitrile at 59.84℃; Kinetics; Mechanism; Solvent; Menshutkin reaction;
In toluene at 45 - 105℃; for 24.5h;

: 288-32-4
1H-imidazole

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1-(3-methylbenzyl)-1H-imidazole

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 120℃; for 2h;	96%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 88-73-3
2-Chloronitrobenzene

: 1211-32-1
2-(m-tolyl)benzo[d]thiazole

Conditions

Conditions	Yield
With N-methylcyclohexylamine; sulfur at 110℃; for 24h; Sealed tube; Inert atmosphere;	96%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 333-20-0
potassium thioacyanate

: 37141-50-7
3-methylbenzyl thiocyanate

Conditions

Conditions	Yield
With silica gel at 30℃; for 48h;	95%
With Fe3O4*SiO2/DABCO In water at 90℃; for 1.5h;	85%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 5059-30-3
2-chloroindole-3-carboxaldehyde

: 75621-55-5
2-Chloro-1-(3-methyl-benzyl)-1H-indole-3-carbaldehyde

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 60℃; for 6h;	95%
With potassium carbonate In acetone at 20℃; for 2h;

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 16635-23-7
phenyltriisopropoxytitanium(IV)

: 620-47-3
1-methyl-3-(phenylmethyl)-benzene

Conditions

Conditions	Yield
With palladium diacetate; Tri(p-tolyl)phosphine In toluene at 25℃; for 2h; Inert atmosphere;	95%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 104-81-4
4-Methylbenzyl bromide

: (3-methyl-benzyl)-(4-methyl-benzyl)-sulfide

Conditions

Conditions	Yield
Stage #1: 4-Methylbenzyl bromide With thiourea In methanol Inert atmosphere; Reflux; Stage #2: With sodium hydroxide In methanol Inert atmosphere; Reflux; Stage #3: 1-chloromethyl-3-methyl-benzene In methanol at 20℃; Inert atmosphere; Reflux;	95%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 126799-82-4
1-(azidomethyl)-3-methylbenzene

Conditions

Conditions	Yield
With sodium azide; potassium iodide In water; acetone at 20℃; for 60h; Inert atmosphere;	95%
With sodium azide In water at 90℃; for 0.25h;	88%
With sodium azide In water at 80℃; for 0.333333h; Green chemistry;	82%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 851233-80-2
potassium 2-cyano-2-methyl-propanoate

: 1228309-98-5
2,2-dimethyl-3-(m-tolyl)propanenitrile

Conditions

Conditions	Yield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(η3-allyl-μ-chloropalladium(II)) In toluene at 110℃; for 12h; Inert atmosphere;	95%

: 273-53-0
benzoxazole

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 2-(3-methylbenzyl)benzo[d]oxazole

Conditions

Conditions	Yield
With NHC-Pd(II)-Im; lithium tert-butoxide In toluene at 130℃; for 3h; Inert atmosphere; Sealed tube;	95%

: 204-02-4
1-H-perimidine

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1-(3-methylbenzyl)perimidine

Conditions

Conditions	Yield
Stage #1: 1-H-perimidine With potassium tert-butylate In dimethyl sulfoxide at 20℃; for 0.5h; Stage #2: 1-chloromethyl-3-methyl-benzene In dimethyl sulfoxide at 110℃; for 0.5h; Microwave irradiation;	95%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 613-84-3
2-hydroxy-5-methylbenzaldehyde

: 5-methyl-2-(3-methylbenzyloxy)benzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In acetone for 6h; Reflux; Inert atmosphere;	95%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 51646-17-4
5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol

: 51646-24-3
5,7-dimethyl-2-(3-methyl-benzylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Conditions

Conditions	Yield
With sodium hydroxide In methanol at 25℃;	94%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 536-74-3
phenylacetylene

: 126800-03-1
1‐(3‐methylbenzyl)‐4‐phenyl‐1H‐1,2,3‐triazole

Conditions

Conditions	Yield
With sodium azide; sodium L-ascorbate In water; tert-butyl alcohol at 70℃; for 0.75h; Huisgen Cycloaddition; Green chemistry; regioselective reaction;	94%
With sodium azide In water at 70℃; for 7h; Huisgen Cycloaddition; Green chemistry; regioselective reaction;	91%
With sodium azide; sodium L-ascorbate In water at 70℃; for 3h;	90%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 35286-92-1
(E)-3,3'-dimethylstilbene

Conditions

Conditions	Yield
With Benzyl phenyl selenoxide; potassium hexamethylsilazane In toluene at 25℃; for 4h; Inert atmosphere;	94%
With potassium phenyl selenide In 1,2-dimethoxyethane for 5h; Inert atmosphere; Sealed tube;	84%
With sodium 4-methylbenzenesulfinate; potassium hydroxide In dimethyl sulfoxide at 100℃; for 16h;	66%

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 552-45-4
1-chloromethyl-2-methylbenzene

: (2-methyl-benzyl)-(3-methyl-benzyl)-sulfide

Conditions

Conditions	Yield
Stage #1: 1-chloromethyl-3-methyl-benzene With thiourea In methanol Inert atmosphere; Reflux; Stage #2: With sodium hydroxide In methanol Inert atmosphere; Reflux; Stage #3: 1-chloromethyl-2-methylbenzene In methanol at 20℃; Inert atmosphere; Reflux;	94%

: 7751-38-4
Diisopropylsilyl dichloride

: 620-19-9
1-chloromethyl-3-methyl-benzene

: 1361982-34-4
diisopropyl(3-methylbenzyl)silanol

Conditions

Conditions	Yield
Stage #1: Diisopropylsilyl dichloride; 1-chloromethyl-3-methyl-benzene With iodine; magnesium In tetrahydrofuran at 20℃; for 1.5h; Inert atmosphere; Stage #2: With water; sodium hydrogencarbonate In tetrahydrofuran; N,N-dimethyl-formamide at 0 - 20℃; for 0.5h; Inert atmosphere;	94%
Stage #1: 1-chloromethyl-3-methyl-benzene With magnesium In diethyl ether at 0℃; Reflux; Stage #2: Diisopropylsilyl dichloride In tetrahydrofuran; diethyl ether at 0℃; for 12h; Reflux; Stage #3: With triethylamine; sodium chloride In tetrahydrofuran; diethyl ether at 0 - 20℃; for 1h;	76%

3-Methylbenzyl chloride Chemical Properties

IUPAC Name: 1-(Chloromethyl)-3-methylbenzene
Canonical SMILES: CC1=CC(=CC=C1)CCl
InChI: InChI=1S/C8H9Cl/c1-7-3-2-4-8(5-7)6-9/h2-5H,6H2,1H3
InChIKey: LZBOHNCMCCSTJX-UHFFFAOYSA-N
Molecular Weight: 140.61006 [g/mol]
Molecular Formula: C₈H₉Cl
XLogP3: 2.9
EINECS: 210-628-9
Index of Refraction: 1.524
Molar Refractivity: 40.84 cm³
Molar Volume: 133.4 cm³
Surface Tension: 33.1 dyne/cm
Density: 1.054 g/cm³
Flash Point: 75.6 °C
Enthalpy of Vaporization: 41.63 kJ/mol
Boiling Point: 197.9 °C at 760 mmHg
Vapour Pressure: 0.521 mmHg at 25 °C
storage temp.: Refrigerator (+4 °C)
Water Solubility: Insoluble
Appearance of m-Xylyl chloride (CAS NO.620-19-9): clear colorless to slightly yellow liquid

3-Methylbenzyl chloride Safety Profile

Hazard Codes: Corrosive C, Irritant Xi
Risk Statements: 34-36/37-36/37/38
R34:Causes burns.
R36/37:Irritating to eyes and respiratory system.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 23-26-27-36/37/39-45-37/39
S23:Do not breathe vapour.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27:Take off immediately all contaminated clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39:Wear suitable gloves and eye/face protection.
RIDADR: UN 3265 8/PG 2
WGK Germany: 2
Hazard Note: Irritant/Corrosive
HazardClass: 8
PackingGroup of m-Xylyl chloride (CAS NO.620-19-9): III

3-Methylbenzyl chloride Specification

m-Xylyl chloride (CAS NO.620-19-9), its Synonyms are 3-(Chloromethyl)toluene ; 3-Methylbenzyl chloride ; alpha-Chloro-m-xylene ; m-(Chloromethyl)toluene ; m-Methylbenzyl chloride ; m-Xylyl-alpha-chloride ; Benzene, 1-(chloromethyl)-3-methyl- (9CI) ; m-Xylene, alpha-chloro- (8CI) .

Product Name

3-Methylbenzyl chloride

Synthetic route

3-Methylbenzyl chloride Chemical Properties

3-Methylbenzyl chloride Safety Profile

3-Methylbenzyl chloride Specification

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