4-(Chloromethyl)benzaldehyde supplier

: 874-86-2
4-cyanobenzyl chloride

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With diisobutylaluminium hydride In chlorobenzene	96%
With hydrogenchloride; diethyl ether; tin(ll) chloride anschl. mit H2O;
With hydrogenchloride; tin(ll) chloride

: 16473-35-1
4-(hydroxymethyl)benzyl chloride

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With pyridinium chlorochromate In dichloromethane at 20℃; for 2h;	94%
With pyridinium chlorochromate In dichloromethane at 0℃;	90%
With manganese(IV) oxide In dichloromethane at 20℃; for 24h;	83%

: 1592-20-7
4-Vinylbenzyl chloride

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With dihydrogen peroxide In water at 100℃; for 4h;	92%
With [bis(acetoxy)iodo]benzene; [(2,2':6',2'-terpyridine)(Cl)RuII(9-oxidophenalenone)] In dichloromethane at 24.84℃; for 16h;

: 52889-83-5
1-(chloromethyl)-4-(methoxymethyl)benzene

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With nitric acid In dichloromethane at 20℃; for 1h;	91%

: 1592-20-7
4-Vinylbenzyl chloride

A: 54589-56-9
4-chloromethylacetophenone

B: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With water; copper(l) chloride In tetrahydrofuran at 20℃; for 48h; Reagent/catalyst; Wacker-Tsuji Olefin Oxidation;	A 89% B n/a

: 59138-96-4
1-bromomethyl-4-chloromethylbenzene

A: 73291-09-5
4-chloromethylbenzaldehyde

B: 623-27-8
terephthalaldehyde,

Conditions

Conditions	Yield
With dipotassium hydrogenphosphate; dimethyl selenoxide In 1,2-dichloro-ethane for 3h;	A 77% B 20%

: 52010-97-6
4-(hydroxylmethyl)benzaldehyde

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With 1-pyrrolidinecarboxaldehyde; benzoyl chloride In 1,4-dioxane at 20 - 40℃; for 24.25h; Sealed tube;	70%
With thionyl chloride; N,N-dimethyl-formamide In toluene at 0 - 20℃; for 16h;	62%
With thionyl chloride In dichloromethane at 0 - 10℃; for 3h;	45.5%
With 1-pyrrolidinecarboxaldehyde; benzoyl chloride In 1,4-dioxane at 20 - 40℃; for 24.25h;	108.3 mg

: 142651-25-0
4-(1',3'-dioxolan-2'-yl)benzyl alcohol

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With hydrogenchloride In water for 24h; Heating / reflux;	68.4%

: 929972-98-5
(4-(chloromethyl)phenyl)(pyrrolidin-1-yl)methanone

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Stage #1: (4-chloromethylphenyl)pyrrolidin-1-ylmethanone With chloromagnesium dimethylaminoborohydride In tetrahydrofuran at 25℃; for 0.5h; Inert atmosphere; Stage #2: With acetaldehyde; acetic acid In tetrahydrofuran; pentane for 4h; Inert atmosphere;	60%

: 174311-81-0
4-<(triphenylmethoxy)methyl>benzyl chloride

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In cyclohexane for 5h; Heating;	43%

: 183057-64-9
4-(hydroxymethyl)benzaldehyde dimethyl acetal

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With hydrogenchloride; thionyl chloride

: 2-(4-Chloromethyl-phenyl)-4-methoxymethyl-[1,3]dioxolane

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 1h; Ambient temperature;

: 2-azido-1-[4-(chloromethyl)phenyl]ethanol

A: (R)-2-azido-1-[4-(chloromethyl)phenyl]ethanol

B: (S)-2-azido-1-[4-(chloromethyl)phenyl]ethanol

C: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With Pd[(-)-sparteine](OAc)2 In toluene for 36h; Heating;

...Expand

: 1592-20-7
4-Vinylbenzyl chloride

A: 6-(chloromethyl)-4-[4-(chloromethyl)phenyl]-3,4-dihydronaphthalen-1(2H)-one

B: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
With oxygen In acetonitrile under 760.051 Torr; for 5h; Product distribution; Further Variations:; Reagents; Irradiation;

: 1642-81-5
p-(chloromethyl)benzoic acid

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 87 percent / K2CO3 / acetone 2: 91 percent / DIBAL-H / CH2Cl2 / -78 °C 3: 90 percent / PCC / CH2Cl2 / 0 °C View Scheme

: 34040-64-7
p-methyloxycarbonylbenzyl chloride

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 91 percent / DIBAL-H / CH2Cl2 / -78 °C 2: 90 percent / PCC / CH2Cl2 / 0 °C View Scheme
Multi-step reaction with 2 steps 1: 98 percent / BH3*THF / tetrahydrofuran / 2 h / 20 °C 2: 83 percent / MnO2 / CH2Cl2 / 24 h / 20 °C View Scheme

: 62172-89-8
4-methyloxymethylhydroxymethylhydroxymethylcyclohexane

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 89 percent / SOCl2 / CH2Cl2 2: 91 percent / HNO3 / CH2Cl2 / 1 h / 20 °C View Scheme

: 1719-82-0
p-methoxymethylbenzoic acid methyl ester

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 94 percent / LiAlH4 / diethyl ether 2: 89 percent / SOCl2 / CH2Cl2 3: 91 percent / HNO3 / CH2Cl2 / 1 h / 20 °C View Scheme

: 67003-50-3
4-(Methoxymethyl)benzoic acid

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 87 percent / SOCl2 / 4 h / -30 - 20 °C 2: 94 percent / LiAlH4 / diethyl ether 3: 89 percent / SOCl2 / CH2Cl2 4: 91 percent / HNO3 / CH2Cl2 / 1 h / 20 °C View Scheme

: 538316-01-7
1,1-dimethylethyl 4-(methoxymethyl)benzoate

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 91 percent / HNO3 / CH2Cl2 / 1 h / 20 °C 2: 87 percent / SOCl2 / 4 h / -30 - 20 °C 3: 94 percent / LiAlH4 / diethyl ether 4: 89 percent / SOCl2 / CH2Cl2 5: 91 percent / HNO3 / CH2Cl2 / 1 h / 20 °C View Scheme

: 182185-47-3
[4-(4-Methoxymethyl-[1,3]dioxolan-2-yl)-phenyl]-methanol

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: PPh3, CCl4 / 3 h / Heating 2: 2 M aq. HCl / ethanol / 1 h / Ambient temperature View Scheme

: 182185-45-1
4-(4-Methoxymethyl-[1,3]dioxolan-2-yl)-benzoic acid methyl ester

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: LiAlH4 / tetrahydrofuran / 16 h / 70 °C 2: PPh3, CCl4 / 3 h / Heating 3: 2 M aq. HCl / ethanol / 1 h / Ambient temperature View Scheme

: 1571-08-0
methyl 4-formylbenzoate

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: Bu4NBr / 72 h / 80 °C 2: LiAlH4 / tetrahydrofuran / 16 h / 70 °C 3: PPh3, CCl4 / 3 h / Heating 4: 2 M aq. HCl / ethanol / 1 h / Ambient temperature View Scheme
Multi-step reaction with 3 steps 1: NH4Cl / methanol 2: LiAlH4 3: HCl, SOCl2 View Scheme

: 589-29-7
p-xylylene glycol

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 75 percent / SOCl2 / CHCl3 / 1 h / 0 °C 2: 70 percent / aq. HCl / toluene; heptane / 2 h / Heating 3: 43 percent / TsOH*H2O / cyclohexane / 5 h / Heating View Scheme
Multi-step reaction with 3 steps 1: 75 percent / SOCl2 / CHCl3 / 1 h / 0 °C 2: 73 percent / DMAP, i-Pr2NEt / N,N-dimethyl-acetamide / 24 h / 40 °C 3: 43 percent / TsOH*H2O / cyclohexane / 5 h / Heating View Scheme
Multi-step reaction with 2 steps 1: 1.) SOCl2 / 1.) CH2Cl2, <10 deg C, 2 h; room temperature, 4 h, 2.) cyclohexane, 15-18 deg C, 3 h 2: 43 percent / TsOH*H2O / cyclohexane / 5 h / Heating View Scheme

: 42228-16-0
methyl 4-(dimethoxymethyl)benzoate

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: LiAlH4 2: HCl, SOCl2 View Scheme

: 81172-89-6
terephthalaldehyde mono(diethylacetal)

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: potassium hydroxide / methanol / 0.08 h 1.2: 16 h / 0 - 20 °C 2.1: hydrogenchloride / 1,4-dioxane; water / 21 h / 20 °C 3.1: 1-pyrrolidinecarboxaldehyde; benzoyl chloride / 1,4-dioxane / 24.25 h / 20 - 40 °C View Scheme

: 125734-44-3
4-(hydroxymethyl)benzaldehyde diethyl acetal

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / 1,4-dioxane; water / 21 h / 20 °C 2: 1-pyrrolidinecarboxaldehyde; benzoyl chloride / 1,4-dioxane / 24.25 h / 20 - 40 °C View Scheme

: 623-27-8
terephthalaldehyde,

: 73291-09-5
4-chloromethylbenzaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium tetrahydroborate / ethanol; tetrahydrofuran / 2 h / 0 °C 2: thionyl chloride; N,N-dimethyl-formamide / toluene / 16 h / 0 - 20 °C View Scheme

: 73291-09-5
4-chloromethylbenzaldehyde

: 74786-02-0
1-(tert-butyldimethylsilyloxy)-1-tert-butoxyethylene

: 839718-27-3
tert-butyl 3-(tert-butyldimethylsilyl)oxy-3-(4-chloromethylphenyl)propionate

Conditions

Conditions	Yield
With di-n-butylbis(trifluoromethanesulfonyloxy)stannane In dichloromethane at -78℃; for 4h; Mukaiyama aldol reaction;	100%
With di-n-butylbis(trifluoromethanesulfonyloxy)stannane In dichloromethane at -78℃; for 2h;	100%

: 73291-09-5
4-chloromethylbenzaldehyde

: 99848-46-1
4-(chloromethyl)benzaldehyde oxime

Conditions

Conditions	Yield
With hydroxylamine In ethanol at 50℃; for 5h;	99%
With hydroxylamine hydrochloride In ethanol at 50℃; for 3h;	98%
With hydroxylamine hydrochloride In ethanol at 50℃; for 3h;	97%
With hydroxylamine hydrochloride In ethanol at 50℃; for 3h;	8.1 g

: 73291-09-5
4-chloromethylbenzaldehyde

: 1349734-81-1
(1E)-4-(chloromethyl)benzaldehyde oxime

Conditions

Conditions	Yield
With hydroxylamine hydrochloride In ethanol at 50℃; for 3h;	98%

: 67-56-1
methanol

: 73291-09-5
4-chloromethylbenzaldehyde

: 130336-16-2
3,5-dichloro-2,2,2-trifluoroacetophenone

: C17H13Cl2F3O3

Conditions

Conditions	Yield
With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; caesium carbonate In tetrahydrofuran at 20℃;	95%

...Expand

: 67-56-1
methanol

: 651-70-7
2,2,2-trifluoro-1-(thiophen-2-yl)ethan-1-one

: 73291-09-5
4-chloromethylbenzaldehyde

: C15H13F3O3S

Conditions

Conditions	Yield
With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; caesium carbonate In tetrahydrofuran at 20℃;	94%

...Expand

: 67-56-1
methanol

: 384-67-8
2-chloro-2,2-difluoroacetophenone

: 73291-09-5
4-chloromethylbenzaldehyde

: C17H15ClF2O3

Conditions

Conditions	Yield
With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; caesium carbonate In tetrahydrofuran at 20℃;	94%

...Expand

: 2127-09-5
2-mercapto-5-nitropyridine

: 73291-09-5
4-chloromethylbenzaldehyde

: 866249-13-0
4-((5-nitropyridine-2-yl)thiomethyl)benzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In acetone	93.3%

: 73291-09-5
4-chloromethylbenzaldehyde

: 113451-59-5
(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

: tert-butyl (1S,4S)-5-(4-formylbenzyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 50℃;	93.1%

: 67-56-1
methanol

: 16184-89-7
4'-bromo-2,2,2-trifluoroacetophenone

: 73291-09-5
4-chloromethylbenzaldehyde

: C17H14BrF3O3

Conditions

Conditions	Yield
With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; caesium carbonate In tetrahydrofuran at 20℃;	93%

...Expand

: 5927-18-4
trimethyl phosphonoacetate

: 73291-09-5
4-chloromethylbenzaldehyde

: 731846-75-6
(E)-methyl 3-[4-(chloromethyl)phenyl]acrylate

Conditions

Conditions	Yield
With sodium methylate In methanol	91%

: 67-56-1
methanol

: 711-38-6
4'-methoxy-2,2,2-trifluoroacetophenone

: 73291-09-5
4-chloromethylbenzaldehyde

: C18H17F3O4

Conditions

Conditions	Yield
With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; caesium carbonate In tetrahydrofuran at 20℃;	91%

...Expand

: 67-56-1
methanol

: 434-45-7
1,1,1-trifluoroacetophenone

: 73291-09-5
4-chloromethylbenzaldehyde

: C17H15F3O3

Conditions

Conditions	Yield
With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; caesium carbonate In tetrahydrofuran at 20℃; for 12h; Reagent/catalyst; Solvent;	91%

...Expand