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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Gram

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Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply But-3-yn-1-ol

Cas:927-74-2

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 3-Butyn-1-ol 927-74-2 GMP Manufacturer

Cas:927-74-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Anhui Dexinjia Biopharm Co., Ltd

As a leading and professional manufacturer of APIs and API intermediates in China,Anhui Dexinjia Biopharm Co., Ltd founded in 2006, Except for the R&D center, our company has built a close cooperation relation with Chinese Academy of Sciences, T

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

High purity 3-Butyn-1-ol 98% TOP1 supplier in China

Cas:927-74-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Butyn-1-ol

Cas:927-74-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

3-Butyn-1-Ol CAS: 927-74-2 But-3-in-1-ol

Cas:927-74-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

CAS No.927-74-2 Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scie

CAS No.927-74-2 3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 927-74-2 with best quality

Cas:927-74-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

3-Butyn-1-ol/ LIDE PHARMA- Factory supply / Best price

Cas:927-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

3-Butyn-1-ol CAS927-74-2

Cas:927-74-2

Min.Order:1 Kilogram

FOB Price: $290.0 / 499.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: 3-Butyn-1-ol Synonyms: 1-Butyn-4-ol;3-butyn-1-0l;3-Butynol;3-Butynyl alcohol;4-Hydroxy-1-butyne;HCequivCCH2CH2OH;3-BUTYNE-1-OL;3-BUTYN-1-OL CAS: 927-74-2 MF

3-Butyn-1-ol

Cas:927-74-2

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Butyn-1-ol 927-74-2

Cas:927-74-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 3-Butyn-1-ol CAS: 927-74-2 MF: C4H6O MW: 70.09 EINECS: 213-161-9 Mol File: 927-74-2.mol 3-Butyn-1-ol Structure 3-Butyn-1-ol Chemical Properties Melting point -63.6 °C (lit.) Boiling point 128.9 °C (li

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

3-Butyn-1-ol CAS:927-74-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

3-Butyn-1-ol CAS:927-74-2

Cas:927-74-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail bes

Factory price 99% 3-Butyn-1-ol CAS:927-74-2

Cas:927-74-2

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:927-74-2

Cas:927-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3-Butyn-1-ol

Cas:927-74-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-Butyn-1-ol

Cas:927-74-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

but-3-yn-1-ol

Cas:927-74-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Butyn-1-Ol

Cas:927-74-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 3-Butyn-1-ol

Cas:927-74-2

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Factory Supply But-3-yn-1-ol

Cas:927-74-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3-Butyn-1-ol

Cas:927-74-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colourless liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Interme

3-Butyn-1-ol

Cas:927-74-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

3-Butyn-1-ol

Cas:927-74-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 3-Butyn-1-ol CAS No.:927-74-2 Molecule Formula:C4H6O Molecule Weight:70.09 Purity: 97.0% Package: 200kg/drum Description:Colorless or light yellow liquid Manufacture Standards:Enterprise Standard TESTING ITEMS

Best Quality 3-Butyn-1-ol with good supplier

Cas:927-74-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-(but-3-yn-1-yloxy)tetrahydropyran
40365-61-5

2-(but-3-yn-1-yloxy)tetrahydropyran

A

2-methoxytetrahydropyran
6581-66-4

2-methoxytetrahydropyran

B

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With methanol; DOWEX 50 W-X2 cation exchange resin at 40℃; for 1h;A n/a
B 98%
pyridine-2-carboxylic acid but-3-ynyl ester

pyridine-2-carboxylic acid but-3-ynyl ester

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With zinc diacetate In methanol; dichloromethane at 20℃; for 1.5h;97%
4-<(triphenylmethyl)oxy>-1-butyne
75014-48-1

4-<(triphenylmethyl)oxy>-1-butyne

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With indium(III) chloride; water In acetonitrile for 2h; Heating;93%
2-(but-3-yn-1-yloxy)tetrahydropyran
40365-61-5

2-(but-3-yn-1-yloxy)tetrahydropyran

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With silica-supported NaHSO4 In methanol at 20℃; for 0.25h;91%
With zinc(II) trifluoromethanesulfonate In methanol at 20℃; for 0.583333h;87%
With pyridinium p-toluenesulfonate In ethanol at 25℃; for 3h;
4-(tert-butyldimethylsilyloxy)-1-butyne
78592-82-2

4-(tert-butyldimethylsilyloxy)-1-butyne

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With sodium hydrogen sulfate; silica gel In dichloromethane at 20℃; for 0.5h;91%
With pyridinium hydrobromide perbromide In methanol at 0℃;81%
1-[(but-3-yn-1-yloxy)methoxy]-2-methoxyethane

1-[(but-3-yn-1-yloxy)methoxy]-2-methoxyethane

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With cerium(III) chloride In acetonitrile for 1.5h; Heating;90%
oxirane
75-21-8

oxirane

lithium acetylide
70277-75-7

lithium acetylide

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
In ammonia at -40℃;88%
In ammonia for 24h;80%
1-but-3-ynyloxymethyl-4-methoxy-benzene
218434-90-3

1-but-3-ynyloxymethyl-4-methoxy-benzene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With carbon tetrabromide In methanol for 3h; ether cleavage; Heating;86%
oxirane
75-21-8

oxirane

acetylene
74-86-2

acetylene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
Multistep reaction;75%
((but-3-yn-1-yloxy)methyl)benzene
22273-77-4

((but-3-yn-1-yloxy)methyl)benzene

A

benzoic acid
65-85-0

benzoic acid

B

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With bis(acetylacetonate)oxovanadium; methyl 3,5-bis((1H-1,2,4-triazol-1-yl)methyl)benzoate; oxygen; sodium acetate at 120℃; for 48h;A 66%
B 54%
formaldehyd
50-00-0

formaldehyd

propargyl bromide
106-96-7

propargyl bromide

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With aluminium; mercury dichloride In tetrahydrofuran55%
With zinc In tetrahydrofuran Addition;
oxirane
75-21-8

oxirane

sodium acetylide
1066-26-8

sodium acetylide

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With ammonia
With ammonia
oxirane
75-21-8

oxirane

sodium acetylide
1066-26-8

sodium acetylide

A

2-but-3-ynyloxy-ethanol
36697-85-5

2-but-3-ynyloxy-ethanol

B

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With ammonia
2,3-butadien-1-ol
18913-31-0

2,3-butadien-1-ol

A

methyl propargyl alcohol
764-01-2

methyl propargyl alcohol

B

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With sodium
3-bromobut-3-en-1-ol
76334-36-6

3-bromobut-3-en-1-ol

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With potassium hydroxide
oxirane
75-21-8

oxirane

ammonia
7664-41-7

ammonia

acetylene
74-86-2

acetylene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
beim Behandeln von Natriumacetylenid;
beim Behandeln von Natriumacetylenid;
3-bromobut-3-en-1-ol
76334-36-6

3-bromobut-3-en-1-ol

aqueous KOH-solution

aqueous KOH-solution

1-butyn-4-ol
927-74-2

1-butyn-4-ol

2,3-butadien-1-ol
18913-31-0

2,3-butadien-1-ol

sodium

sodium

A

methyl propargyl alcohol
764-01-2

methyl propargyl alcohol

B

1-butyn-4-ol
927-74-2

1-butyn-4-ol

oxirane
75-21-8

oxirane

acetylene
74-86-2

acetylene

A

1-butyn-4-ol
927-74-2

1-butyn-4-ol

B

2-bromoethanol
540-51-2

2-bromoethanol

Conditions
ConditionsYield
Stage #1: acetylene With acetylenemagnesium bromide In tetrahydrofuran at -10 - 10℃; for 0.5h;
Stage #2: oxirane In tetrahydrofuran at 35 - 40℃;
3-Hydroxypropanal
2134-29-4

3-Hydroxypropanal

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate
90965-06-3

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

1-butyn-4-ol
927-74-2

1-butyn-4-ol

Conditions
ConditionsYield
With potassium carbonate In methanol at 20℃; for 5.5h; Seyferth-Gilbert Homologation;
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

1-butyn-4-ol
927-74-2

1-butyn-4-ol

2-(but-3-yn-1-yloxy)tetrahydropyran
40365-61-5

2-(but-3-yn-1-yloxy)tetrahydropyran

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane for 16h; Ambient temperature;100%
With pyridinium p-toluenesulfonate In dichloromethane99%
With toluene-4-sulfonic acid In dichloromethane at 0 - 23℃; for 1.08333h; Inert atmosphere;99%
p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

1-butyn-4-ol
927-74-2

1-butyn-4-ol

3-butyn-1-yl p-toluenesulfonate
23418-85-1

3-butyn-1-yl p-toluenesulfonate

Conditions
ConditionsYield
In pyridine; benzene at 0℃; for 14h;100%
With pyridine In dichloromethane at 0℃;100%
With pyridine In dichloromethane at 23℃;100%
1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-bromo-but-3-yn-1-ol
4544-38-1

4-bromo-but-3-yn-1-ol

Conditions
ConditionsYield
With N-Bromosuccinimide; silver nitrate In acetone at 23℃; for 2h; Inert atmosphere;100%
With N-Bromosuccinimide; silver nitrate In acetone at 20℃; for 2h; Inert atmosphere;98%
With N-Bromosuccinimide; silver nitrate In acetone at 25℃; for 1h;95%
benzyl bromide
100-39-0

benzyl bromide

1-butyn-4-ol
927-74-2

1-butyn-4-ol

((but-3-yn-1-yloxy)methyl)benzene
22273-77-4

((but-3-yn-1-yloxy)methyl)benzene

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; sodium hydride In trichlorophosphate Heating;100%
With tetra-(n-butyl)ammonium iodide; sodium hydride In tetrahydrofuran at 23℃; for 5.5h;100%
With tetra-(n-butyl)ammonium iodide; sodium hydride In tetrahydrofuran; mineral oil at 0 - 23℃; for 18h; Inert atmosphere; Sealed tube;100%
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

1-butyn-4-ol
927-74-2

1-butyn-4-ol

methanesulfonic acid but-3-ynyl ester
72486-09-0

methanesulfonic acid but-3-ynyl ester

Conditions
ConditionsYield
With triethylamine at 0 - 20℃;100%
With triethylamine In dichloromethane at 0℃; for 3h;99%
With triethylamine In dichloromethane at 0℃; for 1.25h; Inert atmosphere;99.8%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(trimethylsilyl)but-3-yn-1-ol
2117-12-6

4-(trimethylsilyl)but-3-yn-1-ol

Conditions
ConditionsYield
Stage #1: 3-Butyn-1-ol With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 1h;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran; hexane at -78 - 20℃; for 2h;
100%
Stage #1: 3-Butyn-1-ol With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Schlenk technique; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Schlenk technique; Inert atmosphere;
100%
Stage #1: 3-Butyn-1-ol With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran; hexane at -78 - 20℃; for 2h;
98%
tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(tert-butyldimethylsilyloxy)-1-butyne
78592-82-2

4-(tert-butyldimethylsilyloxy)-1-butyne

Conditions
ConditionsYield
With dmap; triethylamine Substitution; Silylation;100%
With 1H-imidazole In tetrahydrofuran at 20℃; for 3h;100%
With 1H-imidazole In diethyl ether at 100℃; for 1h;100%
allyl bromide
106-95-6

allyl bromide

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(prop-2-en-1-yloxy)but-1-yne
75405-45-7

4-(prop-2-en-1-yloxy)but-1-yne

Conditions
ConditionsYield
With sodium hydride In tert-butyl methyl ether at -5 - 20℃; for 16.25h;100%
With sodium hydride In tetrahydrofuran; diethyl ether70%
With sodium hydride 1.) Et2O, HMPA, RT, 30 min, 2.) Et2O, HMPA, reflux, 2.5 h; Yield given. Multistep reaction;
Stage #1: 3-Butyn-1-ol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; Inert atmosphere;
Stage #2: allyl bromide With tetra-(n-butyl)ammonium iodide In tetrahydrofuran; hexane at 20℃; Inert atmosphere;
Stage #1: 3-Butyn-1-ol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.666667h; Inert atmosphere; Schlenk technique;
Stage #2: allyl bromide With tetra-(n-butyl)ammonium iodide In tetrahydrofuran; mineral oil at 0 - 25℃; for 16h; Inert atmosphere; Schlenk technique;
tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(tert-butyldiphenylsilyloxy)-1-butyne
88158-68-3

4-(tert-butyldiphenylsilyloxy)-1-butyne

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 2h;100%
With 1H-imidazole In dichloromethane at 20℃; for 2h;100%
With 1H-imidazole In N,N-dimethyl-formamide for 0.5h; Ambient temperature;100%
cis-1,2-Dichloroethylene
156-59-2

cis-1,2-Dichloroethylene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

(Z)-6-chlorohex-5-en-3-yn-1-ol
114534-21-3

(Z)-6-chlorohex-5-en-3-yn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-butylamine In benzene at 20℃; for 12h;100%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-butylamine In benzene for 16h;99%
Stage #1: cis-1,2-Dichloroethylene With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-butylamine In benzene for 0.416667h; Condensation;
Stage #2: 3-Butyn-1-ol In benzene at 20℃; for 3h; Condensation;
80%
iodobenzene
591-50-4

iodobenzene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-phenyl-but-3-yn-1-ol
10229-11-5

4-phenyl-but-3-yn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine for 16h; Sonogashira Cross-Coupling; Reflux; Inert atmosphere; Schlenk technique;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 10h; Inert atmosphere;99%
With copper(l) iodide; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp In N,N-dimethyl-formamide at 100℃; Sonogashira reaction;97%
1-butyn-4-ol
927-74-2

1-butyn-4-ol

D-glucal triacetate
2873-29-2

D-glucal triacetate

but-3-yn-1-yl 4,6-di-O-acetyl-2,3-dideoxy-α/β-D-erythro-hex-2-enopyranoside
135195-22-1, 142344-14-7

but-3-yn-1-yl 4,6-di-O-acetyl-2,3-dideoxy-α/β-D-erythro-hex-2-enopyranoside

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane Ambient temperature;100%
With 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; dysprosium(III) trifluoromethanesulfonate at 20℃; for 2h;90%
3-iodo-4-phenylthiophene
176168-47-1

3-iodo-4-phenylthiophene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

3-phenyl-4-(4'-hydroxybutyn-1'-yl)thiophene

3-phenyl-4-(4'-hydroxybutyn-1'-yl)thiophene

Conditions
ConditionsYield
With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) In acetonitrile Heating;100%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) In triethylamine; acetonitrile for 18h; Heating;100%
1-butyn-4-ol
927-74-2

1-butyn-4-ol

(3-iodo-pyridin-4-yl)-carbamic acid tert-butyl ester
211029-67-3

(3-iodo-pyridin-4-yl)-carbamic acid tert-butyl ester

[3-(4-Hydroxy-but-1-ynyl)-pyridin-4-yl]-carbamic acid tert-butyl ester

[3-(4-Hydroxy-but-1-ynyl)-pyridin-4-yl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride at 20℃;100%
1-butyn-4-ol
927-74-2

1-butyn-4-ol

4,6-dichloropyrimidine-5-carboxylic acid chloride
87600-97-3

4,6-dichloropyrimidine-5-carboxylic acid chloride

4,6-dichloro-pyrimidine-5-carboxylic acid but-3-ynyl ester
285991-67-5

4,6-dichloro-pyrimidine-5-carboxylic acid but-3-ynyl ester

Conditions
ConditionsYield
With triethylamine at 0 - 20℃;100%
With triethylamine Substitution;87%
1-butyn-4-ol
927-74-2

1-butyn-4-ol

N,N-dimethyl 3-trimethylsilyl-4-iodo-1H-pyrrole-1-sulfonamide
278167-18-3

N,N-dimethyl 3-trimethylsilyl-4-iodo-1H-pyrrole-1-sulfonamide

N,N-dimethyl 3-trimethylsilyl-4-(4-hydroxy-1-butynyl)-1H-pyrrole-1-sulfonamide

N,N-dimethyl 3-trimethylsilyl-4-(4-hydroxy-1-butynyl)-1H-pyrrole-1-sulfonamide

Conditions
ConditionsYield
With copper(l) iodide; diethylamine; bis-triphenylphosphine-palladium(II) chloride at 20℃; for 7h; cross-coupling; Sonogashira reaction;100%
3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(3-methoxyphenyl)-but-3-yn-1-ol
92587-68-3

4-(3-methoxyphenyl)-but-3-yn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 0℃; for 24h; Sonogashira coupling; Inert atmosphere; Reflux;100%
With tris-(dibenzylideneacetone)dipalladium(0); triethylamine; triphenylphosphine; copper(l) iodide at 70℃; for 24h;82%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 8h; Sonogashira Cross-Coupling; Inert atmosphere;73%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 12h; Inert atmosphere;
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 117℃; for 3h; Sonogashira Cross-Coupling; Inert atmosphere;
1,4-bromoiodobenzene
589-87-7

1,4-bromoiodobenzene

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(4-bromophenyl)-3-butyn-1-ol
59099-79-5

4-(4-bromophenyl)-3-butyn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In dichloromethane at 50℃; Sonogashira reaction;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran for 4h; Inert atmosphere; Reflux;85%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide Schlenk technique;82%
4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

1-butyn-4-ol
927-74-2

1-butyn-4-ol

4-(4-hydroxy-1-butyn-1-yl)benzaldehyde
544707-13-3

4-(4-hydroxy-1-butyn-1-yl)benzaldehyde

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 48h; Sonogashira-Hagihara coupling;91%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at 20℃; Sonogashira Cross-Coupling;
1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

1-butyn-4-ol
927-74-2

1-butyn-4-ol

but-3-yn-1-yl 1H-imidazole-1-carboxylate
909707-34-2

but-3-yn-1-yl 1H-imidazole-1-carboxylate

Conditions
ConditionsYield
In tetrahydrofuran; dichloromethane at 20℃; for 2h;100%
In dichloromethane at 0 - 20℃; for 17h; Inert atmosphere;88%
2-iodo-4-cyanophenol
2296-23-3

2-iodo-4-cyanophenol

1-butyn-4-ol
927-74-2

1-butyn-4-ol

2-(2-hydroxy-ethyl)-benzofuran-5-carbonitrile
919088-04-3

2-(2-hydroxy-ethyl)-benzofuran-5-carbonitrile

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 15h;100%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

1-butyn-4-ol
927-74-2

1-butyn-4-ol

but-3-ynyl-1-oxycarbonyl chloride
190774-49-3

but-3-ynyl-1-oxycarbonyl chloride

Conditions
ConditionsYield
Stage #1: bis(trichloromethyl) carbonate; 3-Butyn-1-ol In tetrahydrofuran at 0 - 20℃;
Stage #2: With pyridine In tetrahydrofuran at 0 - 20℃; for 2h;
100%
In diethyl ether for 12h;
In tetrahydrofuran for 12h; Cooling with ice;
With sodium carbonate In tetrahydrofuran at 0 - 20℃; for 12h;
4-iodopyridine-2-carboxylic acid methyl ester
380381-28-2

4-iodopyridine-2-carboxylic acid methyl ester

1-butyn-4-ol
927-74-2

1-butyn-4-ol

C11H11NO3

C11H11NO3

Conditions
ConditionsYield
With triethylamine; palladium diacetate; copper(l) iodide; triphenylphosphine at 20℃; for 3h;100%
trimethylsilyl trifluoromethanesulfonate
27607-77-8

trimethylsilyl trifluoromethanesulfonate

1-butyn-4-ol
927-74-2

1-butyn-4-ol

1-<(trimethylsilyl)oxy>-4-(trimethylsilyl)-3-butyne
58434-99-4

1-<(trimethylsilyl)oxy>-4-(trimethylsilyl)-3-butyne

Conditions
ConditionsYield
With zinc trifluoromethanesulfonate; triethylamine In dichloromethane at 23℃; for 12h;100%
(((C6H5)2PCH2)2)Pt(CH3CN)(CH(Cl)COOC2H5)(1+)*BF4(1-)=[(((C6H5)2PCH2)2)Pt(CH3CN)(CH(Cl)COOC2H5)]BF4
191790-03-1

(((C6H5)2PCH2)2)Pt(CH3CN)(CH(Cl)COOC2H5)(1+)*BF4(1-)=[(((C6H5)2PCH2)2)Pt(CH3CN)(CH(Cl)COOC2H5)]BF4

1-butyn-4-ol
927-74-2

1-butyn-4-ol

(((C6H5)2PCH2)2)Pt(C4H6O)(CH(Cl)COOC2H5)(1+)*BF4(1-)=[(((C6H5)2PCH2)2)Pt(C4H6O)(CH(Cl)COOC2H5)]BF4
191790-05-3

(((C6H5)2PCH2)2)Pt(C4H6O)(CH(Cl)COOC2H5)(1+)*BF4(1-)=[(((C6H5)2PCH2)2)Pt(C4H6O)(CH(Cl)COOC2H5)]BF4

Conditions
ConditionsYield
In dichloromethane 20°C (15 h);100%
(3-bromo-2-fluorophenyl)carbamic acid tert-butyl ester
848440-23-3

(3-bromo-2-fluorophenyl)carbamic acid tert-butyl ester

1-butyn-4-ol
927-74-2

1-butyn-4-ol

tert-butyl [3-(4-hydroxybut-1-yn-1-yl)-2-fluorophenyl]carbamate
1099766-43-4

tert-butyl [3-(4-hydroxybut-1-yn-1-yl)-2-fluorophenyl]carbamate

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); diisopropylamine for 3h; Reflux;100%
1-butyn-4-ol
927-74-2

1-butyn-4-ol

sodium but-3-yn-1-yl sulfate
1050479-30-5

sodium but-3-yn-1-yl sulfate

Conditions
ConditionsYield
With pyridine; chlorosulfonic acid In tetrachloromethane at 0 - 20℃;100%
C17H18N2O7S
1033702-73-6

C17H18N2O7S

1-butyn-4-ol
927-74-2

1-butyn-4-ol

C21H22N2O7S
1033702-74-7

C21H22N2O7S

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 0.5h; Mitsunobu reaction;100%
(1R,2R,3S,4R)-4-azido-1-<((tert-butyldiphenylsilyl)oxy)methyl>-2,3-(isopropylidenedioxy)cyclopentane
112543-78-9

(1R,2R,3S,4R)-4-azido-1-<((tert-butyldiphenylsilyl)oxy)methyl>-2,3-(isopropylidenedioxy)cyclopentane

1-butyn-4-ol
927-74-2

1-butyn-4-ol

(1R,2S,3R,4R)-4-[(tert-butyldiphenylsilyloxy)methyl]-1-[4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl]-2,3-isopropylidenedioxycyclopentane
1161113-46-7

(1R,2S,3R,4R)-4-[(tert-butyldiphenylsilyloxy)methyl]-1-[4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl]-2,3-isopropylidenedioxycyclopentane

Conditions
ConditionsYield
With copper; copper(II) sulfate In water; tert-butyl alcohol at 125℃; for 0.0166667h; Microwave irradiation;100%
C18H33NO3Si
1196880-24-6

C18H33NO3Si

1-butyn-4-ol
927-74-2

1-butyn-4-ol

C22H39NO4Si
1196880-29-1

C22H39NO4Si

Conditions
ConditionsYield
Stage #1: 3-Butyn-1-ol With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: C18H33NO3Si In tetrahydrofuran; hexane at -78 - 20℃; for 3h;
100%

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